Selection of Recent Publications (2001 to date)

• Circadian Rhythm Disorders and Treatment
• Light and Spectral Sensitivity of Human Circadian System
• Ageing and the circadian system
• Molecular Chronobiology
• Reviews

Circadian Rhythm Disorders and Treatment

• Arendt J, van Someren EJW, Appleton R, Skene DJ, and Akerstedt T (2008) Clinical update: melatonin and sleep disorders. Clinical Med 8: 381-383.
• Hack LM, Lockley SW, Arendt J, and Skene DJ (2003) The effects of low dose 0.5 mg melatonin on the free-running circadian rhythms of blind subjects. J Biol Rhythms 18:420-429.
• Lockley SW, Dijk DJ, Kosti O, Skene DJ, and Arendt J (2008) Alertness, mood and performance rhythm disturbances associated with circadian sleep disorders in the blind. J. Sleep Res17:207-216.
• Skene DJ, and Arendt J (2007) Circadian rhythm sleep disorders in the blind and their treatment with melatonin. Sleep Medicine 8: 651-655.
• Thorne H, Hampton S, Morgan L, Skene DJ, and Arendt J (2008) Differences in sleep, light, and circadian phase in offshore 18:00-06:00 h and 19:00-07:00 h shift workers. Chronobiol Int 25:225-235.

Light and Spectral Sensitivity of Human Circadian System

• Revell VL, Arendt J, Terman M, and Skene DJ (2005) Short-wavelength sensitivity of the human circadian system to phase-advancing light. J Biol Rhythms 20:270-272.
• Revell VL, Arendt J, Fogg LF, and Skene DJ (2006) Alerting effects of light are sensitive to very short wavelengths. Neurosci Letts 399:96-100.
• Revell VL, and Skene DJ (2007) Light-induced melatonin suppression in humans with polychromatic and monochromatic light. Chronobiol Int 24:1125-1137.
• Thapan K, Arendt J, and Skene DJ (2001) An action spectrum for melatonin suppression: evidence for a novel non-rod, non-cone photoreceptor system in humans. J Physiol 535:261-267.
• Warman VL, Dijk DJ, Warman GR, Arendt J, and Skene DJ (2003) Phase advancing human circadian rhythms with short wavelength light. Neurosci Letts 342:37-40.

Ageing and the circadian system

• Herljevic M, Middleton B, Thapan K, and Skene DJ (2005) Light-induced melatonin suppression: Age-related reduction in response to short wavelength light. Experimental Gerontol 40:237-242.
• Sletten TL, Revell VL, Middleton B, Lederle KA, and Skene DJ (2009) Age-related changes in acute and phase advancing responses to monochromatic light. J Biol Rhythms 24:73-84.
• Walters JF, Hampton SM, Ferns GAA, and Skene DJ (2005) Effect of menopause on melatonin and alertness rhythms investigated in constant routine conditions. Chronobiol Int 22:859-872.
• Walters JF, Hampton SM, Deanfield JE, Donald AE, Skene DJ, and Ferns GAA (2006) Circadian variation in endothelial function is attenuated in postmenopausal women. Maturitas 54:294-303.

Molecular Chronobiology

• Archer SN, Robilliard DL, Skene DJ, Smits M, Williams A, Arendt J, and von Schantz M (2003) A length polymorphism in the circadian clock gene Per3 is linked to delayed sleep phase syndrome and extreme diurnal preference. Sleep 26:413-415.
• Carpen JD, Archer SN, Skene DJ, Smits M, and von Schantz M (2005) A single-nucleotide polymorphism in the 5'-untranslated region of the hPER2 gene is associated with diurnal preference. J Sleep Res 14:293-297.
• Jones KHS, Ellis J, von Schantz M, Skene DJ, Dijk D-J, and Archer SN (2007) Age-related change in the association between a polymorphism in the PER3 gene and preferred timing of sleep and waking activities. J Sleep Res 16:12-16.
• Robilliard DL, Archer SN, Arendt J, Lockley SW, Hack LM, English J, Leger D, Smits MG, Williams A, Skene DJ, and Von Schantz M (2002) The 3111 Clock gene polymorphism is not associated with sleep and circadian rhythmicity in phenotypically characterized human subjects. J Sleep Res 11:305-312.
• Viola AU, Archer SN, James LM, Groeger JA, Lo JCY, Skene DJ, von Schantz M, and Dijk D-J (2007) PER3 polymorphism predicts sleep structure and waking performance. Current Biol 17:613-618.

Reviews

• Arendt J, and Skene DJ (2005) Melatonin as a Chronobiotic. Sleep Medicine Reviews 9:25-39.
• Dzaja A, Arber S, Hislop J, Kerkhofs M, Kopp C, Pollmächer T, Polo-Kantola P, Skene DJ, Stenuit P, Tobler I, and Porkka-Heiskanen T (2005) Women's sleep in health and disease. J Psychiatric Res 39:55-76.
• Mistlberger R, and Skene DJ (2004) Social influences on mammalian circadian rhythms: animal and human studies. Biological Rev Cambs Philos Soc 79:533-556.
• Mistlberger R and Skene DJ (2005) Nonphotic entrainment in humans? J Biol Rhythms 20:339-352.
• Skene DJ (2003) Optimization of light and melatonin to phase-shift human circadian rhythms. J Neuroendocrinol 15:438-441.
• Skene DJ, and Arendt J (2006) Human circadian rhythms: Physiological and therapeutic relevance of light and melatonin. Ann. Clin Biochem 43:344-353.
• Skene DJ, and Swaab DF (2003) Melatonin rhythmicity: effect of age and Alzheimer's disease. Exp Gerontol 38:199-206.