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Study Populations

The studies performed by Surrey Clinical Research Centre to date have covered many aspects of CNS research and drug development, and used a wide variety of different volunteers and patients.

Volunteers

Healthy

• Studies involved the following agents: antidepressants, anxiolytics, antihistamines, cognitive enhancers, hypnotics, neuroleptics, NSAIDs, cardiovascular agents, antidiarrhoeals, cognitive enhancers, social substances and antiepileptics
• Safety, tolerance, PK, PD
• Bioequivalence, PK, PD
• Dose ranging, PK, PD
• Shift workers
• Radar operatives

Special Populations

• Japanese subjects

Atypical Populations

• Ex-patients (anxiety, sleep disturbance)
• Caffeine-induced insomnia
• Sleep deprived subjects
• Tobacco smokers
• Benzodiazepine-impaired memory

Elderly

• Antidepressants, anxiolytics, cognitive enhancers, antidementia agents, hypnotics
• PK, PD
• Anxiety rated
• Nutritional/vitamin status rated

Patients (Including Elderly Populations) in Hospital and General Practice

• Major depression
• Mixed anxiety/depression
• Anxiety
• Sleep disturbance/insomnia
• Dementia (Alzheimer’s disease, vascular dementia)
• Organic psychosyndrome
• Generalised anxiety disorder (GAD)
• Surgical (anaesthesia/premedication)
• Allergy (rhinitis, hayfever)
• Accident victims
• Drug abusers