The corporate IT network is a battle-ground of a range of modern threats. Cybercriminals looking to make financial gain, attention-seekers trying to create headlines, professional hackers aiming to steal sensitive documents, and even moles acting as legitimate employees all create significant risks for those tasked with defending the network. To make matters worse, the traditional technology and methods of these defenders has failed to keep pace with the ingenuity of the attackers and the industrialisation of their methods. This seminar will give an overview of the threat landscape and draw on real case studies from investigations done by the Detica Treidan Cyber Intrusion Detection team. Examples of social engineering tricks, exploits, custom malware, and threat correlation will be presented along with descriptions of some of the cutting-edge techniques being used to detect them.