Dr Silvia Pani
Lecturer in Applied Radiation Physics
Qualifications: Laurea, PhD
Email: s.pani@surrey.ac.uk
Phone: Work: 01483 68 2276
Room no: 18 BB 03
Further information
Biography
Silvia Pani was born and brought up in Udine, Italy.
She obtained her "laurea" degree in 1996 and her PhD in 2001 from the University of Trieste. From 2000 to 2004 she worked there as a post-doctoral research assistant on the development of the first synchrotron beamline for “in vivo” mammography. During the same period she worked as a support scientist to external synchrotron users.
In 2004 she was awarded a two-year Marie Curie Intra-European Fellowship, based at University College London, to work on breast imaging using X-ray diffraction CT.
From Autumn 2006 to Summer 2007 she worked at UCL on imaging projects funded by the European Union and by a private company.
In 2007 she moved to Queen Mary, University of London/Barts and The London NHS Trust, where she worked on a Home Office funded project for drug detection using X-ray diffraction.
In 2008 she joined the Physics Department at Surrey as a Lecturer.
Research Interests
Development of X-ray techniques for medical imaging and non-destructive testing, in particular:
- Breast imaging using conventional and novel techniques (diffraction, CT, phase contrast, K-edge subtraction).
- Diffraction microCT for breast tissue characterization.
- Transfer and adaptation of synchrotron-based techniques to the laboratory environment.
- Homeland security (detection of illegal materials).
Research Collaborations
Current and past collaborations include:
Prof Robert Speller, Department of Medical Physics and Bioengineering, University College London
Dr Julie Horrocks, Barts and The London NHS Trust
SYRMEP Group, University of Trieste/Sincrotrone Trieste SCpA
Counter Drug Technologies Team, Home Office Scientific Development Branch
Publications
Highlights
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(2010) 'Characterization of breast tissue using energy-dispersive X-ray diffraction computed tomography'. PERGAMON-ELSEVIER SCIENCE LTD APPLIED RADIATION AND ISOTOPES, 68 (10), pp. 1980-1987.Full text is available at: http://epubs.surrey.ac.uk/715795/
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(2009) 'Modelling an Energy-Dispersive X-Ray Diffraction System for Drug Detection'. IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC IEEE TRANSACTIONS ON NUCLEAR SCIENCE, Berkeley, CA: 56 (3), pp. 1238-1241.Full text is available at: http://epubs.surrey.ac.uk/715789/
- . (2009) 'Multivariate Data Analysis for Drug Identification Using Energy-Dispersive X-Ray Diffraction'. IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC IEEE TRANSACTIONS ON NUCLEAR SCIENCE, Berkeley, CA: Symposium on Radiation Measurements and Applications 56 (3), pp. 1459-1464.
- . (2007) 'Use of a novel controlled drift detector for diffraction enhanced breast imaging'. ELSEVIER SCIENCE BV NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT, Univ Liverpool, Liverpool, ENGLAND: 7th International Conference on Position-Sensitive Detectors 573 (1-2), pp. 133-136.
Journal articles
- . (2012) 'Development and characterization of a laboratory based X-ray diffraction imaging system for material and tissue characterization'. Applied Radiation and Isotopes, 70 (7), pp. 1325-1330.
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(2012) 'Development and characterization of a laboratory based X-ray diffraction imaging system for material and tissue characterization.'. Elsevier Appl Radiat Isot, England: 70 (7), pp. 1325-1330.Full text is available at: http://epubs.surrey.ac.uk/715797/
Abstract
Soft tissues feature a degree of short-range order, giving rise to diffraction patterns with broader peaks than crystalline materials. For this reason, an X-ray diffraction system (XRD) for characterization of soft tissue has less stringent requirements in terms of momentum transfer resolution than the one aimed at characterizing crystalline materials. We present results on the characterization of two energy-dispersive XRD systems. The first was based on conical collimation at 5.9° and the second was based on linear collimation at varying angles between 2° and 10°. The systems include a CdTe detector and a W-anode X-ray source. The angular resolution was measured as a function of sample thickness and scattering angle. Preliminary results confirm the effectiveness of the method for the characterization of biological tissues, showing insensitivity to small changes in angular acceptance and sample thickness, also showing it is possible to combine scattering data obtained at different angles.
- . (2012) 'Applications of X-ray diffraction imaging to Mammography'. Recent Patents on Medical Imaging, 2 (2), pp. 111-119.
- . (2012) 'Breast tissue contrast-simulating materials using energy-dispersive X-ray diffraction'. Applied Radiation and Isotopes,
- . (2012) 'Breast tissue contrast-simulating materials using energy-dispersive X-ray diffraction'. Elsevier Applied Radiation and Isotopes,
- . (2011) 'Pixellated Cd(Zn)Te high-energy X-ray instrument'. JOURNAL OF INSTRUMENTATION, 6 Article number ARTN C12009
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(2010) 'Characterization of breast tissue using energy-dispersive X-ray diffraction computed tomography'. PERGAMON-ELSEVIER SCIENCE LTD APPLIED RADIATION AND ISOTOPES, 68 (10), pp. 1980-1987.Full text is available at: http://epubs.surrey.ac.uk/715795/
- .
(2009) 'Modelling an Energy-Dispersive X-Ray Diffraction System for Drug Detection'. IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC IEEE TRANSACTIONS ON NUCLEAR SCIENCE, Berkeley, CA: 56 (3), pp. 1238-1241.Full text is available at: http://epubs.surrey.ac.uk/715789/
- . (2008) 'Preliminary images from an adaptive imaging system'. IST EDITORIALI POLGRAFICI INT PHYSICA MEDICA, Pisa, ITALY: 24 (2), pp. 117-121.
- . (2008) 'Angular dispersive diffraction microCT of small breast tissue samples'. PERGAMON-ELSEVIER SCIENCE LTD RADIATION PHYSICS AND CHEMISTRY, 77 (4), pp. 373-380.
- . (2007) 'Application of controlled-drift detectors in diffraction enhanced Imaging of tissues'. IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC IEEE TRANSACTIONS ON NUCLEAR SCIENCE, 54 (5), pp. 1474-1480.
- . (2007) 'Adaptive image content-based exposure control for scanning applications in radiography'. Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), 4678 LNCS, pp. 543-552.
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(2005) 'The effects of the imaging system on the validity limits of the ray-optical approach to phase contrast imaging'. AMER ASSOC PHYSICISTS MEDICINE AMER INST PHYSICS MEDICAL PHYSICS, 32 (12), pp. 3617-3627.doi: 10.1118/1.2126207
- . (2005) 'High resolution Ca/P maps of bone architecture in 3D synchrotron radiation microtomographic images'. PERGAMON-ELSEVIER SCIENCE LTD APPLIED RADIATION AND ISOTOPES, 62 (4), pp. 569-575.
- . (2004) 'Breast tomography with synchrotron radiation: preliminary results.'. Phys Med Biol, England: 49 (9), pp. 1739-1754.
- . (2004) 'The I-Imas project: End-Users driven specifications for the design of a novel digital medical imaging system'. IEEE Nuclear Science Symposium Conference Record, 5, pp. 2742-2746.
- . (2004) 'A CCD-based high resolution CT system for analysis of trabecular bone tissue'. IEEE Nuclear Science Symposium Conference Record, 4, pp. 2273-2277.
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(2003) 'A multilayer edge-on single photon counting silicon microstrip detector for innovative imaging techniques in diagnostic radiology'. AMER INST PHYSICS REVIEW OF SCIENTIFIC INSTRUMENTS, 74 (7), pp. 3460-3465.doi: 10.1063/1.1582390
- . (2003) 'Multiple-energy X-ray radiography and digital subtraction for a particle-composition sensor'. PERGAMON-ELSEVIER SCIENCE LTD MINERALS ENGINEERING, 16 (7), pp. 609-617.
- . (2003) 'Diffraction enhanced breast imaging: Assessment of realistic system requirements to improve the diagnostic capabilities of mammography'. IEEE Nuclear Science Symposium Conference Record, 5, pp. 3230-3234.
- . (2003) 'X-Ray diffraction CT of excised breast tissue sections: First results from elettra'. IEEE Nuclear Science Symposium Conference Record, 4, pp. 2330-2334.
- . (2002) 'Signal-to-noise ratio evaluation radiography with synchrotron radiation'. IOP PUBLISHING LTD PHYSICS IN MEDICINE AND BIOLOGY, 47 (22) Article number PII S0031-9155(02)38088-6 , pp. 4093-4105.
- . (2002) 'Grade of fine composite mineral particles by dual-energy X-ray radiography'. ELSEVIER SCIENCE BV INTERNATIONAL JOURNAL OF MINERAL PROCESSING, 67 (1-4) Article number PII S0301-7516(02)00037-6 , pp. 101-122.
- . (2002) 'Preliminary study on extremely small angle x-ray scatter imaging with synchrotron radiation.'. Phys Med Biol, England: 47 (3), pp. 469-480.
- . (2001) 'An innovative digital imaging set-up allowing a low-dose approach to phase contrast applications in the medical field.'. Med Phys, United States: 28 (8), pp. 1610-1619.
- . (2000) 'Experimental evaluation of a simple algorithm to enhance the spatial resolution in scanned radiographic systems.'. Med Phys, United States: 27 (11), pp. 2609-2616.
- . (2000) 'Mammography with synchrotron radiation: phase-detection techniques.'. Radiology, UNITED STATES: 215 (1), pp. 286-293.
- . (2000) 'Imaging evaluation of CsI(Tl) arrays for scintimammography'. IEEE Nuclear Science Symposium and Medical Imaging Conference, 3
- . (2000) 'Feasibility study for SPECT mammography based on compact imagers rotating around breast vertical axis'. IEEE Nuclear Science Symposium and Medical Imaging Conference, 3
Conference papers
- . (2012) 'High resolution dual-tracer brain SPECT with a new high-performance CdTe detector'. SPRINGER EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, Milan, ITALY: 25th Annual Congress of the European-Association-of-Nuclear-Medicine (EANM) 39, pp. S230-S230.
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(2011) 'K-edge subtraction imaging using a pixellated energy-resolving detector'. Proceedings of SPIE: Progress in Biomedical Optics and Imaging, Lake Buena Vista, USA: Medical Imaging 2011: Physics of Medical Imaging 7961doi: 10.1117/12.876577Full text is available at: http://epubs.surrey.ac.uk/715788/
- . (2009) 'Multivariate Data Analysis for Drug Identification Using Energy-Dispersive X-Ray Diffraction'. IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC IEEE TRANSACTIONS ON NUCLEAR SCIENCE, Berkeley, CA: Symposium on Radiation Measurements and Applications 56 (3), pp. 1459-1464.
- . (2009) 'Characterisation of the Components of a Prototype Scanning Intelligent Imaging System for Use in Digital Mammography: The I-ImaS System'. IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC IEEE TRANSACTIONS ON NUCLEAR SCIENCE, Berkeley, CA: Symposium on Radiation Measurements and Applications 56 (3), pp. 1419-1425.
- . (2009) 'Designing an in-field system for illicit drug detection using X-ray diffraction'. IEEE 2009 IEEE Nuclear Science Symposium Conference Record, Orlando, USA: 2009 IEEE Nuclear Science Symposium, pp. 862-867.
- . (2007) 'Use of a novel controlled drift detector for diffraction enhanced breast imaging'. ELSEVIER SCIENCE BV NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT, Univ Liverpool, Liverpool, ENGLAND: 7th International Conference on Position-Sensitive Detectors 573 (1-2), pp. 133-136.
- . (2005) 'Edge on silicon microstrip detectors for medical imaging'. ELSEVIER SCIENCE BV NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT, Lake Windermere, ENGLAND: 12th International Workshop on Vertex Detectors Low Wood (VERTEX 2003) 549 (1-3), pp. 199-204.
- . (2005) 'Evaluation of the endodontic apical seal after post insertion by synchrotron radiation microtomography'. ELSEVIER SCIENCE BV NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT, Trieste, ITALY: 4th Workshop on Medical Applications of Synchrotron Radiation (MARS2004) 548 (1-2), pp. 253-256.
- . (2005) 'MicroCT analysis of calcium/phosphorus ratio maps at different bone sites'. ELSEVIER SCIENCE BV NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT, Trieste, ITALY: 4th Workshop on Medical Applications of Synchrotron Radiation (MARS2004) 548 (1-2), pp. 269-273.
- . (2005) 'Medical applications of synchrotron radiation at the SYRMEP beamline of ELETTRA'. ELSEVIER SCIENCE BV NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT, Trieste, ITALY: 4th Workshop on Medical Applications of Synchrotron Radiation (MARS2004) 548 (1-2), pp. 221-227.
- . (2005) 'Effect of spatial coherence on application of in-line phase contrast imaging to synchrotron radiation mammography'. ELSEVIER SCIENCE BV NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT, Trieste, ITALY: 4th Workshop on Medical Applications of Synchrotron Radiation (MARS2004) 548 (1-2), pp. 155-162.
- . (2005) 'A digital detector for breast computed tomography at the SYRMEP beam line'. ELSEVIER SCIENCE BV NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT, Trieste, ITALY: 4th Workshop on Medical Applications of Synchrotron Radiation (MARS2004) 548 (1-2), pp. 264-268.
- . (2004) 'A detection system for clinical breast tomography with synchrotron radiation'. ELSEVIER SCIENCE BV NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT, Vienna, AUSTRIA: 10th International Vienna Conference on Instrumentation 535 (1-2), pp. 88-92.
- . (2004) 'High-speed single photon counting read out electronics for a digital detection system for clinical synchrotron radiation mammography'. ELSEVIER SCIENCE BV NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT, LA BIODOLA, ITALY: 9th Pisa Meeting on Advanced Detectors 518 (1-2), pp. 415-417.
- . (2004) 'A digital detection system for synchrotron radiation breast tomography'. IEEE 2004 IEEE Nuclear Science Symposium Conference Record, Vols 1-7, Rome, ITALY: Nuclear Science Symposium/Medical Imaging Conference, pp. 4654-4656.
- . (2003) 'FROST: an ASIC for digital mammography with synchrotron radiation'. ELSEVIER SCIENCE BV NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT, UNIV SIEGEN, SIEGEN, GERMANY: 1st International Symposium on Applications of Particle Detectors in Medicine, Biology and Astrophysics (SAMBA 99) 510 (1-2), pp. 51-56.
- . (2003) 'A dedicated system for breast cancer study with combined SPECT-CT modalities'. ELSEVIER SCIENCE BV NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT, ROME, ITALY: 1st Topical Symposium on Functional Breast Imaging with Advanced Detectors 497 (1), pp. 129-134.
- . (2003) 'Morphological breast imaging: tomography and digital mammography with synchrotron radiation'. ELSEVIER SCIENCE BV NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT, ROME, ITALY: 1st Topical Symposium on Functional Breast Imaging with Advanced Detectors 497 (1), pp. 9-13.
- . (2003) 'Simultaneous acquisition of diffraction, scattering and phase-contrast images by means of a multi-layer edge-on microstrip detector'. SPRINGER-VERLAG BERLIN DIGITAL MAMMOGRAPHY, PROCEEDINGS, BREMEN, GERMANY: 6th International Workshop on Digital Mammography, pp. 48-50.
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(2002) 'Breast tomography with synchrotron radiation'. SPIE-INT SOC OPTICAL ENGINEERING MEDICAL IMAGING 2002: PHYSICS OF MEDICAL IMAGING, SAN DIEGO, CA: Medical Imaging 2002 Conference 4682, pp. 228-235.doi: 10.1117/12.465563
- . (2001) 'Combined CT-SPECT tomography system for breast cancer study'. ISTITUTI EDITORIALI E POLGRAFICI INTERNAZIONALI PHYSICA MEDICA, VIENNA, AUSTRIA: 3rd Workshop of the European-Federation-of-Organizations-for-Medical-Physics (ECR-2001) 17 (4), pp. 249-252.
- . (2001) 'FROST: a low-noise high-rate photon counting ASIC for X-ray applications'. ELSEVIER SCIENCE BV NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT, LA BIODOLA, ITALY: 8th Pisa Meeting on Advanced Detectors 461 (1-3), pp. 435-439.
- . (2001) 'Improvements in digital mammography with synchrotron radiation'. MEDICAL PHYSICS PUBLISHING IWDM 2000: 5TH INTERNATIONAL WORKSHOP ON DIGITAL MAMMOGRAPHY, TORONTO, CANADA: 5th International Workshop on Digital Mammography, pp. 65-71.
- . (2000) 'Tomographic imaging with synchrotron radiation'. ISTITUTI EDITORIALI E POLGRAFICI INTERNAZIONALI PHYSICA MEDICA, VIENNA, AUSTRIA: Satellite Symposium of the European-Congress-of-Radiology 16 (3), pp. 155-159.
- . (2000) 'Development of a small-field quasi-monochromatic computer tomography system'. ISTITUTI EDITORIALI E POLGRAFICI INTERNAZIONALI PHYSICA MEDICA, VIENNA, AUSTRIA: Satellite Symposium of the European-Congress-of-Radiology 16 (3), pp. 161-164.
Book chapters
- . (2010) 'Biomedical Sensors'. in Jones D (ed.) Biomedical Sensors Momentum Pr
Teaching
Level HE2 Laboratory
Level HE3 Medical Imaging
MSc in Radiation Detection and Instrumentation: MonteCarlo modelling
MSc in Medical Physics: Ultrasonics Lab
Departmental Duties
Admission Tutor for Physics Undergraduate Programmes
Radiation Protection Supervisor for X-ray labs
Personal Tutoring coordinator
Special Needs coordinator

