Dr Lisa Harris

Biography

I joined the Department of Psychology in October 2008 as a Postdoctoral Researcher in the Cognitive Neuroscience Research Team (CNRT), following the completion of my PhD in the use Magnetic Resonance Spectroscopy (MRS) in characterisation of childhood brain tumours at the University of Birmingham.

I have a range of interests in the use of neuroimaging techniques, but the two main focuses of my current research:

•         Using MRS to better understand the link between brain metabolite and female sex hormones

•         The application of MRS in the assessment of chronic post-concussion syndrome following a mild traumatic brain injury

Research Interests

The primary purpose of my research is to understand the link between brain metabolites and cognition.

Main Research Findings

•         Brain metabolites are modulated by progesterone in young women

•         Those having experienced an mTBI with post concussion syndrome show alterations in their brain metabolites over a year post-injury

Publications

JM Easton, LM Harris, MR Viant, AC Peet and TN Arvanitis
(2010) Linked Metabolites: A tool for the construction of directed metabolic graphs
BMC Bioinformatics, 40(3): p340-349

LM Harris, NP Davies, L MacPherson, S Lateef, K Natarajan, MA Brundler, S Sgouros, M English, TN Arvanitis, RG Grundy and AC Peet
(2008) Magnetic Resonance Spectroscopy in the assessment of Juvenile Pilocytic Astrocytomas
European Journal of Cancer, 44(17): p2640-2647

NP Davies, MP Wilson, LM Harris, K Natarajan, S Lateef, L MacPherson, S Sgouros, RG Grundy, TN Arvanitis and AC Peet
(2008) Identification and characterisation of childhood cerebellar tumours by in vivo proton MRS using discriminant analysis of metabolite profiles
NMR in Biomedicine, 21(8): p908-918

LM Harris, N Davies, L MacPherson, K Foster, S Lateef, K Natarajan, S Sgouros, MA Brundler, TN Arvanitis, RG Grundy and AC Peet
(2007) Use of short echo time 1H MRS for childhood cerebellar tumours prior to histopathological diagnosis
Pediatric Radiology, 37(11): p1101-1109

Conferences

LM Harris, A McNamara, K Moakes, N Masento and A Sterr
Measuring progesterone-related changes in brain metabolites using 3T MRS
7th International Congress of Neuroendocrinology, Rouen, France, July 2010

LM Harris, P Dean, A McNamara and A Sterr
Using 3T Magnetic Resonance Spectroscopy to Assess the Long Term Effects of Mild Traumatic Brain Injury (traditional poster)
ISMRM-ESMRMB Joint Annual Meeting, Stockholm, Sweden, May 2010

NP Davies, MP Wilson, LM Harris, L MacPherson, M-A Brundler, TN Arvanitis, RG Grundy, AC Peet
Pattern recognition of single voxel 1H MRS metabolite profiles for classification and characterisation of childhood brain tumours according to type and grade (oral presentation)
European Society of Magnetic Resonance in Medicine (ESMRMB) Congress, Valencia, October 2008

LM Harris, L MacPherson, TN Arvanitis, D Auer, RG Grundy, D Hargrave, F Howe, T Jaspan, M Leach, P Morgan, K Natarajan, G Payne, D Saunders and AC Peet
1H-Magnetic Resonance Spectroscopy as an aid to the diagnosis of brain stem tumours: a multicentre study (oral presentation)
13th International Symposium on Pediatric Neuro-Oncology, Chicago, June 2008
Neuro-oncology, 10 (3) – p428

LM Harris, NP Davies, L MacPherson, S Lateef, K Natarajan, MA Brundler, S Sgouros, M English, TN Arvanitis, RG Grundy and AC Peet
Magnetic Resonance Spectroscopy in the assessment of Juvenile Pilocytic Astrocytomas (oral presentation)
13th International Symposium on Pediatric Neuro-Oncology, Chicago 2008
Neuro-oncology, 10 (3) – p430

LM Harris, S Wilson, NP Davies, L MacPherson, S Lateef, K Natarajan, M English, TN Arvanitis, RG Grundy and AC Peet
Short echo time single voxel 1H Magnetic Resonance Spectroscopy in the diagnosis of pineal region tumours (oral presentation)
European Society of Paediatric Radiology Conference, Edinburgh, June 2008

MP Saleh, AJ Gibb, LM Harris, NP Davies, K Natarajan, L MacPherson, S Lateef, S Sgouros, RG Grundy, AC Peet and TN Arvanitis
Quantitative Analysis of MRI for Paediatric Cerebellar Tumours (traditional poster)
UK Radiological Conference, Birmingham, June 2008

NP Davies, LM Harris, MP Wilson, K Natarajan, S Lateef, L MacPherson, S Sgouros, MA Brundler, TN Arvanitis, RG Grundy and AC Peet
Correlation of metabolite concentrations estimated from in-vivo MRS of childhood cerebellar tumours with HR-MAS NMR of matched tumour samples - Prognosis of childhood brain tumours by in-vivo 1H MRS (oral presentation)
eTumour Plenary, Nijmegen, October 2007

LM Harris, NP Davies, L MacPherson, S Lateef, K Natarajan, MA Brundler, S Sgouros, RG Grundy, TN Arvanitis and AC Peet
1H-MRS detects differences with location in Juvenile Pilocytic Astrocytomas and predicts response to treatment in supratentorial tumours (oral presentation)
British Chapter of International Society of Magnetic Resonance in Medicine, Birmingham, September 2007

NP Davies, LM Harris, K Natarajan, S Lateef, L MacPherson, S Sgouros, M-A Brundler, TN Arvanitis, RG Grundy and AC Peet
Metabolite profile analysis of childhood brain tumours using quantitative in vivo short TE 1H MRS (oral presentation)
ISMRM-ESMRMB Joint Annual Meeting, Berlin, Germany, May 2007

LM Harris, NP Davies, Y Sun, K Natarajan, L MacPherson, S Sgouros, T Arvanitis, D Hargrave, S Riches, G Payne, M Leach, F Howe, P Morgan, D Auer, T Jaspan, R Grundy and AC Peet
A multicentre study of in vivo 1H MRS of paediatric brain stem tumours (traditional poster)
International Society of Magnetic Resonance in Medicine, Berlin, Germany, 2007

NP Davies, LM Harris, MP Wilson, S Lateef, LM MacPherson, S Sgouros, K Natarajan, T Arvanitis, R Grundy and AC Peet
In vivo 1H MRS and ex vivo MAS of Childhood Brain Tumours (oral presentation)
eTumour Plenary, Barcelona, Spain, January 2007

NP Davies, LM Harris, K Natarajan, S Lateef, L MacPherson, S Sgouros , TN Arvanitis, RG Grundy and AC Peet
Non-invasive identification of cerebellar brain tumours in children using pattern recognition of in vivo 1H Magnetic Resonance Spectroscopy (1H MRS) (traditional poster)
NCRI Cancer Conference, Birmingham, p158-9, September 2006

LM Harris, NP Davies, K Natarajan, S Lateef, L MacPherson, S Sgouros, TN Arvanitis, RG Grundy and AC Peet
In vivo 1H Magnetic Resonance Spectroscopy identifies key metabolite differences between diffuse pontine gliomas and other tumours of the brain stem in children (traditional poster)
NCRI Cancer Conference, Birmingham, p 156, September 2006

MP Wilson, MA Brundler, GM Reynolds, LM Harris, TN Arvanitis, RG Grundy, and AC Peet
1H Magic Angle Spinning Analysis of Childhood Brain Tumour Tissue (oral presentation)
eTumour Plenary, London, June 2006

NP Davies, LM Harris, K Natarajan, S Lateef, L MacPherson, S Sgouros , TN Arvanitis, RG Grundy and AC Peet
Non-invasive identification of cerebellar brain tumours in children using in vivo 1H Magnetic Resonance Spectroscopy (1H MRS): LCModel quantitation vs automatic pattern recognition (oral presentation)
eTumour Plenary, London, June 2006

LM Harris, NP Davies, K Natarajan, S Lateef, L MacPherson, S Sgouros, TN Arvanitis, RG Grundy and AC Peet
Metabolite Profiling of Childhood Brain Tumours (oral presentation)
In Research Meeting Abstracts, Children’s Brain Tumour Research Centre, The University of Nottingham, Nottingham: UK, April 2006