Dr Julie Seibt

Lecturer in Sleep and Plasticity

Qualifications: BSc, MSc, PhD

Email:
Phone: Work: 01483 68 4167
Room no: 21 MA 00

Office hours

Monday-Friday

Further information

Biography

2016-present   Lecturer in Sleep & Plasticity. Faculty of Health and Medical Sciences, University of Surrey, UK.

2010-2016      Post-doctoral Research Fellow in Neuroscience. University of Bern/ Charité Universtätsmedizin Berlin

2006-2010      Post-doctoral Research Fellow in Neuroscience. University of Pennsylvania, USA

2005-2006      Post-doctoral Research Fellow in Developmental Neurobiology. University of Brussels, Belgium

2001-2005      PhD in Neurobiology, Claude Bernard University - Lyon (France)

2001                MSc . in Neuroscience, Claude Bernard University - Lyon (France)

2000                BSc in Cognitive Science, Provence University - Marseille (France)

Research Interests

Sleep, circadian rhythms & plasticity
Influence on cortical dendritic functions (calcium activity and experience-dependent gene & protein expression)

Physiology of neural oscillations
Physiology of brain oscillations; interaction with cognition and plasticity

Sleep, circadian rhythms & endoplasmic reticulum (ER)
Influence of sleep deprivation, experience and aging on ER calcium activity

Funding received
. 2012-2016 - Marie Curie International Reintegration Grants (FP7-IRG), PERISLEEP-268273; 48 months (PI)
. 2008-2010 - Pickwick Postdoctoral Fellowship from the National Sleep Foundation; 24 months (PI)
. 2005-2006 - EMBO Short-Term Fellowship – 3 months
. 2004-2005 - End of PhD Grant, French Medical Research Foundation (FRM); 12 months
. 2002-2003 - Marie Curie Training Site Fellowship (EURON); 5 months
. 2001-2004 - Merit grant from the French Ministry of Research and Technology (MRT); 36 months

Research Collaborations

Dr. Jini Naidoo, Center for Sleep and Circadian Neurobiology, University of Pennsylvania, USA
Prof. Matthew Larkum, NeuroCure Cluster of Excellence, Charité-Universtätsmedizin Berlin, Germany

Publications

1. Dumoulin Bridi M.C. , Aton S.J. , Seibt J., Renouard L., Coleman T., Frank M.G. (2015) Rapid eye movement sleep promotes cortical plasticity in the developing cat, Sci. Adv. 1(e1500105)

2. Aton S.J., Broussard C., Dumoulin M.C., Seibt J., Watson A., Coleman T., Frank M.G. (2013) Visual experience and subsequent sleep induce sequential plastic changes in putative inhibitory and excitatory cortical neurons, PNAS 110(8):3101-6

3. Seibt J., Armant O., Le Digarcher A., Castro D., Ramesh V., Journot L., Guillemot F., Vanderhaeghen P., Bouschet T. (2012) Expression at the imprinted Dlk1-Gtl2 locus is regulated by proneural genes in the developing telencephalon, PLoS ONE 7(11)

4. Seibt J. and Frank M.G. (2012) Translation regulation in sleep: making experience last. Communicative & Integrative Biology. 5(5): 1-5.

5. Seibt J., Dumoulin M.C., Aton S.J., Coleman T., Watson A., Frank M.G.(2012) Protein synthesis consolidates sleep-dependent cortical plasticity in vivo, Current Biol. 22(8): 676 - 682.

6. Aton S.J., Seibt J., Frank M.G. (2009) Sleep and Memory. In: Encyclopedia of Life Sciences (Levitan I, ed), Chichester: John Wiley & Sons.

7. Aton S.J.*, Seibt J.*, Dumoulin M.C., Coleman T., Shiraishi M., Frank M.G. (2009) The sedating antidepressant trazodone impairs sleep-dependent cortical plasticity, PLoS ONE 4(7).
* These two authors contributed equally to this work

8. Uebele V.N., Nuss C.E., Santarelli V.P., Garson S.L., Kraus R.L., Stauffer S.R., Barrow  J.C.,  Koblan K.S., Renger J.J., Aton S., Seibt J., Dumoulin M., Jha SK., Coleman T., Frank M.G.(2009) T-type calcium channels regulate cortical plasticity in vivo. NeuroReport 20(3): 257- 62.

9. Aton S.J, Seibt J., Dumoulin M.C., Jha S.K., Steinmetz N., Coleman T., Naidoo N., Frank  M.G. (2009) Mechanisms of sleep-dependent consolidation of cortical plasticity. Neuron 61(3): 454-66.

10. Seibt J., Aton S.J., Jha S.K., Coleman T., Dumoulin M.C., Frank M.G.(2008) The non-benzodiazepine Zolpidem impairs sleep-dependent cortical plasticity. SLEEP 31(10): 1381-1392.

11. Schuurmans C., Armant O., Nieto M., Stenman J.M., Britz O., Klenin N., Brown C., Langevin L.M., Seibt J., Tang H., Cunningham J.M., Dyck R., Walsh C., Campbell K., Polleux F., Guillemot F. (2004) Sequential phases of cortical specification involve Neurogenin-dependent and -independent pathways. EMBO J. 23(14):2892-902.

12. Dufour A., Seibt J., Passante L., Depaepe V., Ciossek T., Frisén J., Kullander K., Flanagan J.G., Polleux F., Vanderhaeghen P. (2003) Area specificity and topography of thalamocortical projections are controlled by ephrin/Eph genes. Neuron. 39(3):453-65.

13. Seibt J., Schuurmans C., Gradwhol G., Dehay C., Vanderhaeghen P., Guillemot F., Polleux F. (2003) Neurogenin2 specifies the connectivity of thalamic neurons by controlling axon responsiveness to intermediate target cues. Neuron 39(3):439-52.

Affiliations

2007-Present Society of Neuroscience (SfN)
2007-Present Sleep Research Society (SRS)

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