Magnetic field effects in spin coupled radical pairs: Can oscillating magnetic fields be used to influence the efficacy of drugs?

This project explores computationally how oscillating magnetic fields influence the biology of reactive oxygen species by acting on spin-coupled radical pairs.

Start date
1 October 2021
Duration
Standard project duration is 3 years
Application deadline
Funding information
  • Full UK tuition fee covered
  • Stipend at £15,609 p.a.
  • Personal computer (provided by the department)

This research project is one of a number of projects at this institution. It is in competition for funding with one or more of these projects. Usually the project which receives the best applicant will be awarded the funding.

About

Degradable polymers containing thioesters in the backbone are promising for biomedical applications. This project will use computational methods to predict and rationalise the formation of such polymers and their degradation under biological conditions. Specifically, the influence of oscillating magnetic fields on the behaviour of reactive oxygen species (ROS) will be explored. The overarching goal is to understand how magnetic fields could be used to trigger a ROS-mediated degradation of injected degradable polymers (which, in turn, could cause the release of encapsulated drugs). A background/interest in computational chemistry is essential. If interested, you can also be trained on synthetic methods to accompany the theoretical work. 

Related links
Leverhulme Quantum Biology Doctoral Training Centre UK Research and Innovation

Eligibility criteria

Applicants should have an undergraduate or masters degree in a relevant field such as a physical science or chemistry. 

Applicants are welcomed from UK and international students. 

English language requirements

IELTS minimum 6.5 overall with 6.0 in Writing, or equivalent

How to apply

Applications should be submitted via the Quantum Biology programme page on the "Apply" tab. Please clearly state the studentship title and supervisor on your application.


Application deadline

Contact details

Peter Roth
34 AZ 03
Telephone: +44 (0)1483 686396
E-mail: p.roth@surrey.ac.uk

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