Textile diagnostic wound dressings
This PhD project will develop wearable biochemical sensors for wound model systems in collaboration with The University of Wollongong. Textile electrofluidics will allow separation of wound components for enhanced sensing. The sensors will conform to the wound to allow on-body measurements.
Start date1 October 2023
Funding sourceUniversity of Surrey
Full tuition fee cover, stipend of c £17,000 p.a. and a £3,000 Research Training Support Grant.
Chronic wounds are wounds that fail to show a timely improvement during treatment and those that exceed a 3-month healing process. Biomarkers that can predict chronic wounds include blood pressure, temperature, oxygen, pH, lactate, glucose and the proinflammatory cytokine interleukin-6 (IL-6). IL-6 can then lead to over-stimulated metalloprotease (MMP) production. Chronic wounds, often associated with infection, present excess protease expression, due to both MMPs and bacterial proteases since bacteria release proteases to create a more favourable growth environment during infection.
Wound fluids are complex matrices, which present difficulties for analysis. Separation of wound fluid components would improve analysis and allow more specific sensing with better outcomes. Electrofluidics are a developing textile-based approach to interrogate, manipulate, and quantify target species during electrodriven separations on threads/textiles.
Combining the separating power of electrofluidics with textile-based sensing for proteases will generate a sensor, capable of unambiguous sensing for infection in chronic wounds.
Related linksBio-sensing and wearables in healthcare
All facilities required to do the work are available at Surrey and/or Wollongong.
If applying please confirm your application by emailing Dr Carol Crean at email@example.com
Open to UK and international candidates.
Applicants are expected to hold a first or upper-second class degree in a relevant discipline or a lower second plus a good Masters degree (distinction normally required).
IELTS Academic: 6.5 or above (or equivalent) with 6.0 in each individual category.
How to apply
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