Davide Messina

Dr Davide Messina


Teaching Fellow in Veterinary Public Health
DVM, Resident ECVPH (PM), MRCVS

About

Teaching

Publications

Inaki Deza-Cruz, Alexandre de Menezes, Brian Gardner, Ilknur Aktan, Sarhad Alnajjar, Martha Elizabeth Betson, Adriana Cabal Rosel, Manuela Caniça, Mark Chambers, Georgina Tarrant, Francesca Marie Contadini, Olukayode Daramola, Rani de la Rivière, Mary Bernadette Egan, Abel Bulamu Ekiri, Catherine Finnegan, Laura Cristina Gonzalez Villeta, Richard Green, Belinda Suzette Hall, Marwa Hassan, Martin Hawes, Sara Rebecca Healy, Lisa Marie Holbrook, Guldane Damla Kaya, Prashant Kumar, Roberto Marcello La Ragione, Daniel James Maupin, Jai W. Mehat, Davide Messina, Kelly Moon, Elizabeth Mumford, Gordon Nichols, Daniel V. Olivença, Joaquin Prada, Claire Price, Christopher John Proudman, Retha Queenan, Miguel Ramos, Jaime Riccomini Closa, Jennifer Ritchie, Lorenzo Santorelli, Nick Selemetas, Matt Spick, Yashwanth Subbannayya, Shelini Surendran, Pedro Teixeira, Mukunthan Tharmakulasingam, Damian Valle, Arnoud H. M. Van Vliet, Marco Videira, Hazel Wallace-Williams, Klara Wanelik, Markus Woegerbauer, Danika Wright, Giovanni Lo Iacono (2025)Mapping the evidence of the effects of environmental factors on the prevalence of antibiotic resistance in the non-built environment, In: Environment international Elsevier

Background: Antibiotic resistance increasingly threatens the interconnected health of humans, animals, and the environment. While misuse of antibiotics is a known driver, environmental factors also play a critical role. A balanced One Health approach—including the environmental sector—is necessary to understand the emergence and spread of resistance. Methods: We systematically searched English-language literature (1990–2021) in MEDLINE, Embase, and Web of Science, plus grey literature. Titles, abstracts, and keywords were screened, followed by full-text reviews using a structured codebook and dual-reviewer assessments. Results: Of 13,667 records screened, 738 met the inclusion criteria. Most studies focused on freshwater and terrestrial environments, particularly associated with wastewater or manure sources. Evidence of research has predominantly focused on Escherichia coli and Pseudomonas spp., with a concentration on ARGs conferring resistance to sulphonamides (sul1–3), tetracyclines (tet), and beta-lactams. Additionally, the People’s Republic of China has produced a third of the studies—twice that of the next country, the United States—and research was largely domestic, with closely linked author networks. Conclusion: Significant evidence gaps persist in understanding antibiotic resistance in non-built environments, particularly in marine, atmospheric, and non-agricultural set65 tings. Stressors such as climate change and microplastics remain notably under-explored. There is also an urgent need for more research in low-income regions, which face higher risks of antibiotic resistance, to support the development of targeted, evidence-based interventions.

Nadia Maria Lopez Urena, UMER CHAUDHRY, Rafael Calero Bernal, Santiago Cano Alsua, DAVIDE MESSINA, FRANCISCO MIGUEL EVANGELISTA, MARTHA ELIZABETH BETSON, Marco Lalle, Pikka Jokelainen, Luis Miguel Ortega Mora, Gema Alvarez Garcia (2022)Contamination of Soil, Water, Fresh Produce, and Bivalve Mollusks with Toxoplasma gondii Oocysts: A Systematic Review, In: Microorganisms (Basel)10(3)517 MDPI

Toxoplasma gondii is a major foodborne pathogen capable of infecting all warm-blooded animals, including humans. Although oocyst-associated toxoplasmosis outbreaks have been documented, the relevance of the environmental transmission route remains poorly investigated. Thus, we carried out an extensive systematic review on T. gondii oocyst contamination of soil, water, fresh produce, and mollusk bivalves, following the PRISMA guidelines. Studies published up to the end of 2020 were searched for in public databases and screened. The reference sections of the selected articles were examined to identify additional studies. A total of 102 out of 3201 articles were selected: 34 articles focused on soil, 40 focused on water, 23 focused on fresh produce (vegetables/fruits), and 21 focused on bivalve mollusks. Toxoplasma gondii oocysts were found in all matrices worldwide, with detection rates ranging from 0.09% (1/1109) to 100% (8/8) using bioassay or PCR-based detection methods. There was a high heterogeneity (I-2 = 98.9%), which was influenced by both the sampling strategy (e.g., sampling site and sample type, sample composition, sample origin, season, number of samples, cat presence) and methodology (recovery and detection methods). Harmonized approaches are needed for the detection of T. gondii in different environmental matrices in order to obtain robust and comparable results.