Understanding how redox regulation processes facilitate platelet activation.

This exciting new project aims to explore how redox mediators interact with platelets, how they can regulate signalling proteins and pathways and how these interactions can be targeted to develop better therapeutics. 

The studentship is fully funded.

Start date

1 October 2024


3.5 years

Application deadline

Funding information

The University of Surrey offers a stipend of £19,237 p/a (UKRI rate).


Platelets are tiny circulating blood cells which prevent bleeding from damaged blood vessels (haemostasis) by becoming active at the site of injury. In addition to this crucial role, platelets can be activated inappropriately (thrombosis) leading to heart attack or stroke. 

Platelets release a range of redox-active substances which can bind to adjacent platelets and mediate chemical changes to surface receptors to modulate downstream cell signalling.  The successful student will investigate how these platelet-released substances regulate platelet signalling pathways and how this can be targeted for the development of better therapies.

This project will equip the student with skills in a wide range of techniques including the use of specialist tests of platelet function, cell migration, cell and molecular biology assays, mass spectrometry and microscopy.

Eligibility criteria

You will need to meet the minimum entry requirements for our Veterinary medicine and Science PHD programme.

Applicants should have a first-class or upper second-class honours or equivalents in:

  • Biochemistry
  • Biomedical Sciences,
  • Biomedical Engineering
  • Biological Sciences
  • Physiology

Or similar subjects.

Practical experience of cell biology, platelet biology or cell signalling is desirable but not essential.

How to apply

Applications should be submitted via the Veterinary medicine and Science PHD programme page. In place of a research proposal you should upload a document stating the title of the project that you wish to apply for and the name of the relevant supervisor.

Veterinary Medicine and Science PhD

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Application deadline

Contact details

Lisa Holbrook
E-mail: l.holbrook@surrey.ac.uk

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