University of Surrey joins global effort to combat a devastating tropical disease
A devastating tropical disease that affects over 240 million people worldwide is the subject of a new international project co-led by the University of Surrey. The project, known as DRIVERS, is funded to the tune of £8.1 million by the Wellcome Trust.

Schistosomiasis is a major public health issue caused by parasitic worms and particularly affecting populations in sub-Saharan Africa. Despite decades of mass drug administration, the disease remains entrenched in many communities. The DRIVERS project aims to uncover why current treatments are failing and provide evidence-based recommendations to improve disease control and move closer to elimination.
By joining forces with experts in epidemiology, immunology, genetics and health policy from Cameroon, Côte D’Ivoire, Malawi and the UK, the team will investigate the key factors driving poor treatment outcomes and rapid reinfection.
The DRIVERS project will analyse data from affected communities in Côte d’Ivoire and Malawi to identify the root causes of reduced drug efficacy and help develop improved models to better predict the impact of targeted treatment strategies, which will be shared with other affected countries and with the World Health Organization (WHO).
I am excited to be working with global experts to really tease out why drug treatment is not effective in some people, and why certain communities continue to have such high transmission despite repeated mass drug treatments. Findings will be rapidly shared with other affected countries and colleagues at the World Health Organization, to provide evidence-based recommendations to help us move towards eliminating this debilitating disease as a public health problemProfessor Poppy Lamberton, study lead from the University of Glasgow
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