Dr Ayman M. Ibrahim , PhD
Academic and research departments
Department of Comparative Biomedical Sciences, Faculty of Health and Medical Sciences.About
Biography
Ayman Ibrahim is a cardiovascular scientist with a multidisciplinary research background including extracellular matrix (ECM) biology, cardiac electrophysiology, induced pluripotent stem cell (iPSC) modeling, and translational cardiovascular medicine. He earned his PhD from the University of Glasgow, where his research focused on ECM remodeling and fibroblast–epithelial interactions during tissue morphogenesis and cancer progression. Dr. Ibrahim has been part of the Magdi Yacoub Heart Foundation’s Aswan Heart Centre Research team, working in collaboration with Imperial College London and the Magdi Yacoub Institute in Harefield. His projects have bridged basic science with clinical cardiology, exploring myocardial and vascular remodeling, fibrosis, and inflammation in hypertrophic cardiomyopathy (HCM). He used patient-specific induced pluripotent stem cells -derived cardiomyocytes model to investigate genotype–phenotype relationships, particularly the impact of myosin heavy chain-7 mutations on calcium handling, contractility, and electrophysiological properties.
In addition to his ECM research, Dr. Ibrahim’s recent work at the University of Göttingen has focused on compartment-specific reactive oxygen species (ROS) production in cardiomyocytes, linking mitochondrial dysfunction to electrophysiological and contractile abnormalities.