Dr Kourosh R Ahmadi

1: Sobczyńska-Malefora A, Delvin E, McCaddon A, Ahmadi KR, Harrington DJ.

Vitamin B₁₂ status in health and disease: a critical review.

Diagnosis of deficiency and insufficiency - clinical and laboratory pitfalls.

Crit Rev Clin Lab Sci. 2021 Apr 21:1-31. doi: 10.1080/10408363.2021.1885339.

Epub ahead of print. PMID: 33881359.

2: Darling AL, Blackbourn DJ, Ahmadi KR, Lanham-New SA. Very high prevalence of

25-hydroxyvitamin D deficiency in 6433 UK South Asian adults: analysis of the UK

Biobank Cohort. Br J Nutr. 2021 Feb 28;125(4):448-459. doi:

10.1017/S0007114520002779. Epub 2020 Jul 22. PMID: 32693845; PMCID: PMC7844605.

3: Dib MJ, Elliott R, Ahmadi KR. A critical evaluation of results from genome-

wide association studies of micronutrient status and their utility in the

practice of precision nutrition. Br J Nutr. 2019 Jul 28;122(2):121-130. doi:

10.1017/S0007114519001119. Epub 2019 Jul 31. PMID: 31362796.

4: Dalmia A, Dib MJ, Maude H, Harrington DJ, Sobczyńska-Malefora A, Andrew T,

Ahmadi KR. A genetic epidemiological study in British adults and older adults

shows a high heritability of the combined indicator of vitamin B₁₂

status (cB₁₂) and connects B₁₂ status with utilization of

mitochondrial substrates and energy metabolism. J Nutr Biochem. 2019

Aug;70:156-163. doi: 10.1016/j.jnutbio.2019.04.008. Epub 2019 May 14. PMID:

31203192.

5: Nash AJ, Mandaviya PR, Dib MJ, Uitterlinden AG, van Meurs J, Heil SG, Andrew

T, Ahmadi KR. Interaction between plasma homocysteine and the MTHFR c.677C > T

polymorphism is associated with site-specific changes in DNA methylation in

humans. FASEB J. 2019 Jan;33(1):833-843. doi: 10.1096/fj.201800400R. Epub 2018

Aug 6. PMID: 30080444.

6: Darling AL, Blackbourn DJ, Ahmadi KR, Lanham-New SA. Vitamin D supplement use

and associated demographic, dietary and lifestyle factors in 8024 South Asians

aged 40-69 years: analysis of the UK Biobank cohort. Public Health Nutr. 2018

Oct;21(14):2678-2688. doi: 10.1017/S1368980018001404. Epub 2018 Jun 25. PMID:

29936916.

7: Mao J, Vanderlelie JJ, Perkins AV, Redman CW, Ahmadi KR, Rayman MP. Genetic

polymorphisms that affect selenium status and response to selenium

supplementation in United Kingdom pregnant women. Am J Clin Nutr. 2016

Jan;103(1):100-6. doi: 10.3945/ajcn.115.114231. Epub 2015 Dec 16. PMID:

26675765; PMCID: PMC4691667.

8: Allum F, Shao X, Guénard F, Simon MM, Busche S, Caron M, Lambourne J, Lessard

J, Tandre K, Hedman ÅK, Kwan T, Ge B; Multiple Tissue Human Expression Resource

Consortium, Rönnblom L, McCarthy MI, Deloukas P, Richmond T, Burgess D, Spector

TD, Tchernof A, Marceau S, Lathrop M, Vohl MC, Pastinen T, Grundberg E. Erratum:

Characterization of functional methylomes by next-generation capture sequencing

identifies novel disease-associated variants. Nat Commun. 2015 Jul 29;6:8016.

doi: 10.1038/ncomms9016. Erratum for: Nat Commun. 2015;6:7211. PMID: 26219997;

PMCID: PMC7188456.

9: Allum F, Shao X, Guénard F, Simon MM, Busche S, Caron M, Lambourne J, Lessard

J, Tandre K, Hedman ÅK, Kwan T, Ge B; Multiple Tissue Human Expression Resource

Consortium, Rönnblom L, McCarthy MI, Deloukas P, Richmond T, Burgess D, Spector

TD, Tchernof A, Marceau S, Lathrop M, Vohl MC, Pastinen T, Grundberg E.

Characterization of functional methylomes by next-generation capture sequencing

identifies novel disease-associated variants. Nat Commun. 2015 May 29;6:7211.

doi: 10.1038/ncomms8211. Erratum in: Nat Commun. 2015;6:8016. PMID: 26021296;

PMCID: PMC4544751.

10: Locke AE, Kahali B, Berndt SI, Justice AE, Pers TH, Day FR, Powell C,

Vedantam S, Buchkovich ML, Yang J, Croteau-Chonka DC, Esko T, Fall T, Ferreira

T, Gustafsson S, Kutalik Z, Luan J, Mägi R, Randall JC, Winkler TW, Wood AR,

Workalemahu T, Faul JD, Smith JA, Zhao JH, Zhao W, Chen J, Fehrmann R, Hedman

ÅK, Karjalainen J, Schmidt EM, Absher D, Amin N, Anderson D, Beekman M, Bolton

JL, Bragg-Gresham JL, Buyske S, Demirkan A, Deng G, Ehret GB, Feenstra B,

Feitosa MF, Fischer K, Goel A, Gong J, Jackson AU, Kanoni S, Kleber ME,

Kristiansson K, Lim U, Lotay V, Mangino M, Leach IM, Medina-Gomez C, Medland SE,

Nalls MA, Palmer CD, Pasko D, Pechlivanis S, Peters MJ, Prokopenko I, Shungin D,

Stančáková A, Strawbridge RJ, Sung YJ, Tanaka T, Teumer A, Trompet S, van der

Laan SW, van Setten J, Van Vliet-Ostaptchouk JV, Wang Z, Yengo L, Zhang W,

Isaacs A, Albrecht E, Ärnlöv J, Arscott GM, Attwood AP, Bandinelli S, Barrett A,

Bas IN, Bellis C, Bennett AJ, Berne C, Blagieva R, Blüher M, Böhringer S,

Bonnycastle LL, Böttcher Y, Boyd HA, Bruinenberg M, Caspersen IH, Chen YI,

Clarke R, Daw EW, de Craen AJM, Delgado G, Dimitriou M, Doney ASF, Eklund N,

Estrada K, Eury E, Folkersen L, Fraser RM, Garcia ME, Geller F, Giedraitis V,

Gigante B, Go AS, Golay A, Goodall AH, Gordon SD, Gorski M, Grabe HJ, Grallert

H, Grammer TB, Gräßler J, Grönberg H, Groves CJ, Gusto G, Haessler J, Hall P,

Haller T, Hallmans G, Hartman CA, Hassinen M, Hayward C, Heard-Costa NL, Helmer

Q, Hengstenberg C, Holmen O, Hottenga JJ, James AL, Jeff JM, Johansson Å, Jolley

J, Juliusdottir T, Kinnunen L, Koenig W, Koskenvuo M, Kratzer W, Laitinen J,

Lamina C, Leander K, Lee NR, Lichtner P, Lind L, Lindström J, Lo KS, Lobbens S,

Lorbeer R, Lu Y, Mach F, Magnusson PKE, Mahajan A, McArdle WL, McLachlan S,

Menni C, Merger S, Mihailov E, Milani L, Moayyeri A, Monda KL, Morken MA, Mulas

A, Müller G, Müller-Nurasyid M, Musk AW, Nagaraja R, Nöthen MM, Nolte IM, Pilz

S, Rayner NW, Renstrom F, Rettig R, Ried JS, Ripke S, Robertson NR, Rose LM,

Sanna S, Scharnagl H, Scholtens S, Schumacher FR, Scott WR, Seufferlein T, Shi

J, Smith AV, Smolonska J, Stanton AV, Steinthorsdottir V, Stirrups K, Stringham

HM, Sundström J, Swertz MA, Swift AJ, Syvänen AC, Tan ST, Tayo BO, Thorand B,

Thorleifsson G, Tyrer JP, Uh HW, Vandenput L, Verhulst FC, Vermeulen SH, Verweij

N, Vonk JM, Waite LL, Warren HR, Waterworth D, Weedon MN, Wilkens LR, Willenborg

C, Wilsgaard T, Wojczynski MK, Wong A, Wright AF, Zhang Q; LifeLines Cohort

Study, Brennan EP, Choi M, Dastani Z, Drong AW, Eriksson P, Franco-Cereceda A,

Gådin JR, Gharavi AG, Goddard ME, Handsaker RE, Huang J, Karpe F, Kathiresan S,

Keildson S, Kiryluk K, Kubo M, Lee JY, Liang L, Lifton RP, Ma B, McCarroll SA,

McKnight AJ, Min JL, Moffatt MF, Montgomery GW, Murabito JM, Nicholson G, Nyholt

DR, Okada Y, Perry JRB, Dorajoo R, Reinmaa E, Salem RM, Sandholm N, Scott RA,

Stolk L, Takahashi A, Tanaka T, van 't Hooft FM, Vinkhuyzen AAE, Westra HJ,

Zheng W, Zondervan KT; ADIPOGen Consortium; AGEN-BMI Working Group;

CARDIOGRAMplusC4D Consortium; CKDGen Consortium; GLGC; ICBP; MAGIC

Investigators; MuTHER Consortium; MIGen Consortium; PAGE Consortium; ReproGen

Consortium; GENIE Consortium; International Endogene Consortium, Heath AC,

Arveiler D, Bakker SJL, Beilby J, Bergman RN, Blangero J, Bovet P, Campbell H,

Caulfield MJ, Cesana G, Chakravarti A, Chasman DI, Chines PS, Collins FS,

Crawford DC, Cupples LA, Cusi D, Danesh J, de Faire U, den Ruijter HM,

Dominiczak AF, Erbel R, Erdmann J, Eriksson JG, Farrall M, Felix SB, Ferrannini

E, Ferrières J, Ford I, Forouhi NG, Forrester T, Franco OH, Gansevoort RT,

Gejman PV, Gieger C, Gottesman O, Gudnason V, Gyllensten U, Hall AS, Harris TB,

Hattersley AT, Hicks AA, Hindorff LA, Hingorani AD, Hofman A, Homuth G, Hovingh

GK, Humphries SE, Hunt SC, Hyppönen E, Illig T, Jacobs KB, Jarvelin MR, Jöckel

KH, Johansen B, Jousilahti P, Jukema JW, Jula AM, Kaprio J, Kastelein JJP,

Keinanen-Kiukaanniemi SM, Kiemeney LA, Knekt P, Kooner JS, Kooperberg C, Kovacs

P, Kraja AT, Kumari M, Kuusisto J, Lakka TA, Langenberg C, Marchand LL,

Lehtimäki T, Lyssenko V, Männistö S, Marette A, Matise TC, McKenzie CA, McKnight

B, Moll FL, Morris AD, Morris AP, Murray JC, Nelis M, Ohlsson C, Oldehinkel AJ,

Ong KK, Madden PAF, Pasterkamp G, Peden JF, Peters A, Postma DS, Pramstaller PP,

Price JF, Qi L, Raitakari OT, Rankinen T, Rao DC, Rice TK, Ridker PM, Rioux JD,

Ritchie MD, Rudan I, Salomaa V, Samani NJ, Saramies J, Sarzynski MA, Schunkert

H, Schwarz PEH, Sever P, Shuldiner AR, Sinisalo J, Stolk RP, Strauch K, Tönjes

A, Trégouët DA, Tremblay A, Tremoli E, Virtamo J, Vohl MC, Völker U, Waeber G,

Willemsen G, Witteman JC, Zillikens MC, Adair LS, Amouyel P, Asselbergs FW,

Assimes TL, Bochud M, Boehm BO, Boerwinkle E, Bornstein SR, Bottinger EP,

Bouchard C, Cauchi S, Chambers JC, Chanock SJ, Cooper RS, de Bakker PIW,

Dedoussis G, Ferrucci L, Franks PW, Froguel P, Groop LC, Haiman CA, Hamsten A,

Hui J, Hunter DJ, Hveem K, Kaplan RC, Kivimaki M, Kuh D, Laakso M, Liu Y, Martin

NG, März W, Melbye M, Metspalu A, Moebus S, Munroe PB, Njølstad I, Oostra BA,

Palmer CNA, Pedersen NL, Perola M, Pérusse L, Peters U, Power C, Quertermous T,

Rauramaa R, Rivadeneira F, Saaristo TE, Saleheen D, Sattar N, Schadt EE,

Schlessinger D, Slagboom PE, Snieder H, Spector TD, Thorsteinsdottir U, Stumvoll

M, Tuomilehto J, Uitterlinden AG, Uusitupa M, van der Harst P, Walker M,

Wallaschofski H, Wareham NJ, Watkins H, Weir DR, Wichmann HE, Wilson JF, Zanen

P, Borecki IB, Deloukas P, Fox CS, Heid IM, O'Connell JR, Strachan DP,

Stefansson K, van Duijn CM, Abecasis GR, Franke L, Frayling TM, McCarthy MI,

Visscher PM, Scherag A, Willer CJ, Boehnke M, Mohlke KL, Lindgren CM, Beckmann

JS, Barroso I, North KE, Ingelsson E, Hirschhorn JN, Loos RJF, Speliotes EK.

Genetic studies of body mass index yield new insights for obesity biology.

Nature. 2015 Feb 12;518(7538):197-206. doi: 10.1038/nature14177. PMID: 25673413;

PMCID: PMC4382211.

11: Shungin D, Winkler TW, Croteau-Chonka DC, Ferreira T, Locke AE, Mägi R,

Strawbridge RJ, Pers TH, Fischer K, Justice AE, Workalemahu T, Wu JMW,

Buchkovich ML, Heard-Costa NL, Roman TS, Drong AW, Song C, Gustafsson S, Day FR,

Esko T, Fall T, Kutalik Z, Luan J, Randall JC, Scherag A, Vedantam S, Wood AR,

Chen J, Fehrmann R, Karjalainen J, Kahali B, Liu CT, Schmidt EM, Absher D, Amin

N, Anderson D, Beekman M, Bragg-Gresham JL, Buyske S, Demirkan A, Ehret GB,

Feitosa MF, Goel A, Jackson AU, Johnson T, Kleber ME, Kristiansson K, Mangino M,

Leach IM, Medina-Gomez C, Palmer CD, Pasko D, Pechlivanis S, Peters MJ,

Prokopenko I, Stančáková A, Sung YJ, Tanaka T, Teumer A, Van Vliet-Ostaptchouk

JV, Yengo L, Zhang W, Albrecht E, Ärnlöv J, Arscott GM, Bandinelli S, Barrett A,

Bellis C, Bennett AJ, Berne C, Blüher M, Böhringer S, Bonnet F, Böttcher Y,

Bruinenberg M, Carba DB, Caspersen IH, Clarke R, Daw EW, Deelen J, Deelman E,

Delgado G, Doney AS, Eklund N, Erdos MR, Estrada K, Eury E, Friedrich N, Garcia

ME, Giedraitis V, Gigante B, Go AS, Golay A, Grallert H, Grammer TB, Gräßler J,

Grewal J, Groves CJ, Haller T, Hallmans G, Hartman CA, Hassinen M, Hayward C,

Heikkilä K, Herzig KH, Helmer Q, Hillege HL, Holmen O, Hunt SC, Isaacs A,

Ittermann T, James AL, Johansson I, Juliusdottir T, Kalafati IP, Kinnunen L,

Koenig W, Kooner IK, Kratzer W, Lamina C, Leander K, Lee NR, Lichtner P, Lind L,

Lindström J, Lobbens S, Lorentzon M, Mach F, Magnusson PK, Mahajan A, McArdle

WL, Menni C, Merger S, Mihailov E, Milani L, Mills R, Moayyeri A, Monda KL,

Mooijaart SP, Mühleisen TW, Mulas A, Müller G, Müller-Nurasyid M, Nagaraja R,

Nalls MA, Narisu N, Glorioso N, Nolte IM, Olden M, Rayner NW, Renstrom F, Ried

JS, Robertson NR, Rose LM, Sanna S, Scharnagl H, Scholtens S, Sennblad B,

Seufferlein T, Sitlani CM, Smith AV, Stirrups K, Stringham HM, Sundström J,

Swertz MA, Swift AJ, Syvänen AC, Tayo BO, Thorand B, Thorleifsson G, Tomaschitz

A, Troffa C, van Oort FV, Verweij N, Vonk JM, Waite LL, Wennauer R, Wilsgaard T,

Wojczynski MK, Wong A, Zhang Q, Zhao JH, Brennan EP, Choi M, Eriksson P,

Folkersen L, Franco-Cereceda A, Gharavi AG, Hedman ÅK, Hivert MF, Huang J,

Kanoni S, Karpe F, Keildson S, Kiryluk K, Liang L, Lifton RP, Ma B, McKnight AJ,

McPherson R, Metspalu A, Min JL, Moffatt MF, Montgomery GW, Murabito JM,

Nicholson G, Nyholt DR, Olsson C, Perry JR, Reinmaa E, Salem RM, Sandholm N,

Schadt EE, Scott RA, Stolk L, Vallejo EE, Westra HJ, Zondervan KT; ADIPOGen

Consortium; CARDIOGRAMplusC4D Consortium; CKDGen Consortium; GEFOS Consortium;

GENIE Consortium; GLGC; ICBP; International Endogene Consortium; LifeLines

Cohort Study; MAGIC Investigators; MuTHER Consortium; PAGE Consortium; ReproGen

Consortium, Amouyel P, Arveiler D, Bakker SJ, Beilby J, Bergman RN, Blangero J,

Brown MJ, Burnier M, Campbell H, Chakravarti A, Chines PS, Claudi-Boehm S,

Collins FS, Crawford DC, Danesh J, de Faire U, de Geus EJ, Dörr M, Erbel R,

Eriksson JG, Farrall M, Ferrannini E, Ferrières J, Forouhi NG, Forrester T,

Franco OH, Gansevoort RT, Gieger C, Gudnason V, Haiman CA, Harris TB, Hattersley

AT, Heliövaara M, Hicks AA, Hingorani AD, Hoffmann W, Hofman A, Homuth G,

Humphries SE, Hyppönen E, Illig T, Jarvelin MR, Johansen B, Jousilahti P, Jula

AM, Kaprio J, Kee F, Keinanen-Kiukaanniemi SM, Kooner JS, Kooperberg C, Kovacs

P, Kraja AT, Kumari M, Kuulasmaa K, Kuusisto J, Lakka TA, Langenberg C, Le

Marchand L, Lehtimäki T, Lyssenko V, Männistö S, Marette A, Matise TC, McKenzie

CA, McKnight B, Musk AW, Möhlenkamp S, Morris AD, Nelis M, Ohlsson C, Oldehinkel

AJ, Ong KK, Palmer LJ, Penninx BW, Peters A, Pramstaller PP, Raitakari OT,

Rankinen T, Rao DC, Rice TK, Ridker PM, Ritchie MD, Rudan I, Salomaa V, Samani

NJ, Saramies J, Sarzynski MA, Schwarz PE, Shuldiner AR, Staessen JA,

Steinthorsdottir V, Stolk RP, Strauch K, Tönjes A, Tremblay A, Tremoli E, Vohl

MC, Völker U, Vollenweider P, Wilson JF, Witteman JC, Adair LS, Bochud M, Boehm

BO, Bornstein SR, Bouchard C, Cauchi S, Caulfield MJ, Chambers JC, Chasman DI,

Cooper RS, Dedoussis G, Ferrucci L, Froguel P, Grabe HJ, Hamsten A, Hui J, Hveem

K, Jöckel KH, Kivimaki M, Kuh D, Laakso M, Liu Y, März W, Munroe PB, Njølstad I,

Oostra BA, Palmer CN, Pedersen NL, Perola M, Pérusse L, Peters U, Power C,

Quertermous T, Rauramaa R, Rivadeneira F, Saaristo TE, Saleheen D, Sinisalo J,

Slagboom PE, Snieder H, Spector TD, Stefansson K, Stumvoll M, Tuomilehto J,

Uitterlinden AG, Uusitupa M, van der Harst P, Veronesi G, Walker M, Wareham NJ,

Watkins H, Wichmann HE, Abecasis GR, Assimes TL, Berndt SI, Boehnke M, Borecki

IB, Deloukas P, Franke L, Frayling TM, Groop LC, Hunter DJ, Kaplan RC, O'Connell

JR, Qi L, Schlessinger D, Strachan DP, Thorsteinsdottir U, van Duijn CM, Willer

CJ, Visscher PM, Yang J, Hirschhorn JN, Zillikens MC, McCarthy MI, Speliotes EK,

North KE, Fox CS, Barroso I, Franks PW, Ingelsson E, Heid IM, Loos RJ, Cupples

LA, Morris AP, Lindgren CM, Mohlke KL. New genetic loci link adipose and insulin

biology to body fat distribution. Nature. 2015 Feb 12;518(7538):187-196. doi:

10.1038/nature14132. PMID: 25673412; PMCID: PMC4338562.

12: Cotlarciuc I, Malik R, Holliday EG, Ahmadi KR, Paré G, Psaty BM, Fornage M,

Hasan N, Rinne PE, Ikram MA, Markus HS, Rosand J, Mitchell BD, Kittner SJ,

Meschia JF, van Meurs JB, Uitterlinden AG, Worrall BB, Dichgans M, Sharma P;

METASTROKE and the International Stroke Genetics Consortium. Effect of genetic

variants associated with plasma homocysteine levels on stroke risk. Stroke. 2014

Jul;45(7):1920-4. doi: 10.1161/STROKEAHA.114.005208. Epub 2014 May 20. PMID:

24846872; PMCID: PMC4083192.

13: Ahmadi KR, Andrew T. Opportunism: a panacea for implementation of whole-

genome sequencing studies in nutrigenomics research? Genes Nutr. 2014

Mar;9(2):387. doi: 10.1007/s12263-014-0387-5. Epub 2014 Feb 18. PMID: 24535715;

PMCID: PMC3968294.

14: Bell JT, Loomis AK, Butcher LM, Gao F, Zhang B, Hyde CL, Sun J, Wu H, Ward

K, Harris J, Scollen S, Davies MN, Schalkwyk LC, Mill J; MuTHER Consortium,

Williams FM, Li N, Deloukas P, Beck S, McMahon SB, Wang J, John SL, Spector TD.

Differential methylation of the TRPA1 promoter in pain sensitivity. Nat Commun.

2014;5:2978. doi: 10.1038/ncomms3978. PMID: 24496475; PMCID: PMC3926001.

15: Grundberg E, Meduri E, Sandling JK, Hedman AK, Keildson S, Buil A, Busche S,

Yuan W, Nisbet J, Sekowska M, Wilk A, Barrett A, Small KS, Ge B, Caron M, Shin

SY; Multiple Tissue Human Expression Resource Consortium, Lathrop M, Dermitzakis

ET, McCarthy MI, Spector TD, Bell JT, Deloukas P. Global analysis of DNA

methylation variation in adipose tissue from twins reveals links to disease-

associated variants in distal regulatory elements. Am J Hum Genet. 2013 Nov

7;93(5):876-90. doi: 10.1016/j.ajhg.2013.10.004. Epub 2013 Oct 31. Erratum in:

Am J Hum Genet. 2013 Dec 5;93(6):1158. PMID: 24183450; PMCID: PMC3824131.

16: Glass D, Viñuela A, Davies MN, Ramasamy A, Parts L, Knowles D, Brown AA,

Hedman AK, Small KS, Buil A, Grundberg E, Nica AC, Di Meglio P, Nestle FO, Ryten

M; UK Brain Expression consortium; MuTHER consortium, Durbin R, McCarthy MI,

Deloukas P, Dermitzakis ET, Weale ME, Bataille V, Spector TD. Gene expression

changes with age in skin, adipose tissue, blood and brain. Genome Biol. 2013 Jul

26;14(7):R75. doi: 10.1186/gb-2013-14-7-r75. PMID: 23889843; PMCID: PMC4054017.

17: van Meurs JB, Pare G, Schwartz SM, Hazra A, Tanaka T, Vermeulen SH,

Cotlarciuc I, Yuan X, Mälarstig A, Bandinelli S, Bis JC, Blom H, Brown MJ, Chen

C, Chen YD, Clarke RJ, Dehghan A, Erdmann J, Ferrucci L, Hamsten A, Hofman A,

Hunter DJ, Goel A, Johnson AD, Kathiresan S, Kampman E, Kiel DP, Kiemeney LA,

Chambers JC, Kraft P, Lindemans J, McKnight B, Nelson CP, O'Donnell CJ, Psaty

BM, Ridker PM, Rivadeneira F, Rose LM, Seedorf U, Siscovick DS, Schunkert H,

Selhub J, Ueland PM, Vollenweider P, Waeber G, Waterworth DM, Watkins H,

Witteman JC, den Heijer M, Jacques P, Uitterlinden AG, Kooner JS, Rader DJ,

Reilly MP, Mooser V, Chasman DI, Samani NJ, Ahmadi KR. Common genetic loci

influencing plasma homocysteine concentrations and their effect on risk of

coronary artery disease. Am J Clin Nutr. 2013 Sep;98(3):668-76. doi:

10.3945/ajcn.112.044545. Epub 2013 Jul 3. PMID: 23824729; PMCID: PMC4321227.

18: Andrew T, Gill R, Gillham-Nasenya I, Ahmadi KR. Unravelling the basis of

variability in cobalamin levels in the general population. Br J Nutr. 2013 Nov

14;110(9):1672-9. doi: 10.1017/S0007114513000974. Epub 2013 Apr 29. PMID:

23628113.

19: Saxena R, Saleheen D, Been LF, Garavito ML, Braun T, Bjonnes A, Young R, Ho

WK, Rasheed A, Frossard P, Sim X, Hassanali N, Radha V, Chidambaram M, Liju S,

Rees SD, Ng DP, Wong TY, Yamauchi T, Hara K, Tanaka Y, Hirose H, McCarthy MI,

Morris AP; DIAGRAM; MuTHER; AGEN, Basit A, Barnett AH, Katulanda P, Matthews D,

Mohan V, Wander GS, Singh JR, Mehra NK, Ralhan S, Kamboh MI, Mulvihill JJ,

Maegawa H, Tobe K, Maeda S, Cho YS, Tai ES, Kelly MA, Chambers JC, Kooner JS,

Kadowaki T, Deloukas P, Rader DJ, Danesh J, Sanghera DK. Genome-wide association

study identifies a novel locus contributing to type 2 diabetes susceptibility in

Sikhs of Punjabi origin from India. Diabetes. 2013 May;62(5):1746-55. doi:

10.2337/db12-1077. Epub 2013 Jan 8. PMID: 23300278; PMCID: PMC3636649.

20: Rahmioglu N, Heaton J, Clement G, Gill R, Surdulescu G, Zlobecka K, Hodgkiss

D, Smith NW, Ahmadi KR. Genome-wide association study reveals a complex genetic

architecture underpinning-induced CYP3A4 enzyme activity. Eur J Drug Metab

Pharmacokinet. 2013 Mar;38(1):63-7. doi: 10.1007/s13318-012-0103-z. Epub 2012

Sep 4. PMID: 22945461.

21: Grundberg E, Small KS, Hedman ÅK, Nica AC, Buil A, Keildson S, Bell JT, Yang

TP, Meduri E, Barrett A, Nisbett J, Sekowska M, Wilk A, Shin SY, Glass D,

Travers M, Min JL, Ring S, Ho K, Thorleifsson G, Kong A, Thorsteindottir U,

Ainali C, Dimas AS, Hassanali N, Ingle C, Knowles D, Krestyaninova M, Lowe CE,

Di Meglio P, Montgomery SB, Parts L, Potter S, Surdulescu G, Tsaprouni L, Tsoka

S, Bataille V, Durbin R, Nestle FO, O'Rahilly S, Soranzo N, Lindgren CM,

Zondervan KT, Ahmadi KR, Schadt EE, Stefansson K, Smith GD, McCarthy MI,

Deloukas P, Dermitzakis ET, Spector TD; Multiple Tissue Human Expression

Resource (MuTHER) Consortium. Mapping cis- and trans-regulatory effects across

multiple tissues in twins. Nat Genet. 2012 Oct;44(10):1084-9. doi:

10.1038/ng.2394. Epub 2012 Sep 2. PMID: 22941192; PMCID: PMC3784328.

22: Okada Y, Sim X, Go MJ, Wu JY, Gu D, Takeuchi F, Takahashi A, Maeda S,

Tsunoda T, Chen P, Lim SC, Wong TY, Liu J, Young TL, Aung T, Seielstad M, Teo

YY, Kim YJ, Lee JY, Han BG, Kang D, Chen CH, Tsai FJ, Chang LC, Fann SJ, Mei H,

Rao DC, Hixson JE, Chen S, Katsuya T, Isono M, Ogihara T, Chambers JC, Zhang W,

Kooner JS; KidneyGen Consortium; CKDGen Consortium, Albrecht E; GUGC consortium,

Yamamoto K, Kubo M, Nakamura Y, Kamatani N, Kato N, He J, Chen YT, Cho YS, Tai

ES, Tanaka T. Meta-analysis identifies multiple loci associated with kidney

function-related traits in east Asian populations. Nat Genet. 2012 Jul

15;44(8):904-9. doi: 10.1038/ng.2352. PMID: 22797727; PMCID: PMC4737645.

23: Manning AK, Hivert MF, Scott RA, Grimsby JL, Bouatia-Naji N, Chen H, Rybin

D, Liu CT, Bielak LF, Prokopenko I, Amin N, Barnes D, Cadby G, Hottenga JJ,

Ingelsson E, Jackson AU, Johnson T, Kanoni S, Ladenvall C, Lagou V, Lahti J,

Lecoeur C, Liu Y, Martinez-Larrad MT, Montasser ME, Navarro P, Perry JR,

Rasmussen-Torvik LJ, Salo P, Sattar N, Shungin D, Strawbridge RJ, Tanaka T, van

Duijn CM, An P, de Andrade M, Andrews JS, Aspelund T, Atalay M, Aulchenko Y,

Balkau B, Bandinelli S, Beckmann JS, Beilby JP, Bellis C, Bergman RN, Blangero

J, Boban M, Boehnke M, Boerwinkle E, Bonnycastle LL, Boomsma DI, Borecki IB,

Böttcher Y, Bouchard C, Brunner E, Budimir D, Campbell H, Carlson O, Chines PS,

Clarke R, Collins FS, Corbatón-Anchuelo A, Couper D, de Faire U, Dedoussis GV,

Deloukas P, Dimitriou M, Egan JM, Eiriksdottir G, Erdos MR, Eriksson JG, Eury E,

Ferrucci L, Ford I, Forouhi NG, Fox CS, Franzosi MG, Franks PW, Frayling TM,

Froguel P, Galan P, de Geus E, Gigante B, Glazer NL, Goel A, Groop L, Gudnason

V, Hallmans G, Hamsten A, Hansson O, Harris TB, Hayward C, Heath S, Hercberg S,

Hicks AA, Hingorani A, Hofman A, Hui J, Hung J, Jarvelin MR, Jhun MA, Johnson

PC, Jukema JW, Jula A, Kao WH, Kaprio J, Kardia SL, Keinanen-Kiukaanniemi S,

Kivimaki M, Kolcic I, Kovacs P, Kumari M, Kuusisto J, Kyvik KO, Laakso M, Lakka

T, Lannfelt L, Lathrop GM, Launer LJ, Leander K, Li G, Lind L, Lindstrom J,

Lobbens S, Loos RJ, Luan J, Lyssenko V, Mägi R, Magnusson PK, Marmot M, Meneton

P, Mohlke KL, Mooser V, Morken MA, Miljkovic I, Narisu N, O'Connell J, Ong KK,

Oostra BA, Palmer LJ, Palotie A, Pankow JS, Peden JF, Pedersen NL, Pehlic M,

Peltonen L, Penninx B, Pericic M, Perola M, Perusse L, Peyser PA, Polasek O,

Pramstaller PP, Province MA, Räikkönen K, Rauramaa R, Rehnberg E, Rice K, Rotter

JI, Rudan I, Ruokonen A, Saaristo T, Sabater-Lleal M, Salomaa V, Savage DB,

Saxena R, Schwarz P, Seedorf U, Sennblad B, Serrano-Rios M, Shuldiner AR,

Sijbrands EJ, Siscovick DS, Smit JH, Small KS, Smith NL, Smith AV, Stančáková A,

Stirrups K, Stumvoll M, Sun YV, Swift AJ, Tönjes A, Tuomilehto J, Trompet S,

Uitterlinden AG, Uusitupa M, Vikström M, Vitart V, Vohl MC, Voight BF,

Vollenweider P, Waeber G, Waterworth DM, Watkins H, Wheeler E, Widen E, Wild SH,

Willems SM, Willemsen G, Wilson JF, Witteman JC, Wright AF, Yaghootkar H,

Zelenika D, Zemunik T, Zgaga L; DIAbetes Genetics Replication And Meta-analysis

(DIAGRAM) Consortium; Multiple Tissue Human Expression Resource (MUTHER)

Consortium, Wareham NJ, McCarthy MI, Barroso I, Watanabe RM, Florez JC, Dupuis

J, Meigs JB, Langenberg C. A genome-wide approach accounting for body mass index

identifies genetic variants influencing fasting glycemic traits and insulin

resistance. Nat Genet. 2012 May 13;44(6):659-69. doi: 10.1038/ng.2274. PMID:

22581228; PMCID: PMC3613127.

24: Bell JT, Tsai PC, Yang TP, Pidsley R, Nisbet J, Glass D, Mangino M, Zhai G,

Zhang F, Valdes A, Shin SY, Dempster EL, Murray RM, Grundberg E, Hedman AK, Nica

A, Small KS; MuTHER Consortium, Dermitzakis ET, McCarthy MI, Mill J, Spector TD,

Deloukas P. Epigenome-wide scans identify differentially methylated regions for

age and age-related phenotypes in a healthy ageing population. PLoS Genet.

2012;8(4):e1002629. doi: 10.1371/journal.pgen.1002629. Epub 2012 Apr 19. PMID:

22532803; PMCID: PMC3330116.

25: Chambers JC, Zhang W, Sehmi J, Li X, Wass MN, Van der Harst P, Holm H, Sanna

S, Kavousi M, Baumeister SE, Coin LJ, Deng G, Gieger C, Heard-Costa NL, Hottenga

JJ, Kühnel B, Kumar V, Lagou V, Liang L, Luan J, Vidal PM, Mateo Leach I,

O'Reilly PF, Peden JF, Rahmioglu N, Soininen P, Speliotes EK, Yuan X,

Thorleifsson G, Alizadeh BZ, Atwood LD, Borecki IB, Brown MJ, Charoen P, Cucca

F, Das D, de Geus EJ, Dixon AL, Döring A, Ehret G, Eyjolfsson GI, Farrall M,

Forouhi NG, Friedrich N, Goessling W, Gudbjartsson DF, Harris TB, Hartikainen

AL, Heath S, Hirschfield GM, Hofman A, Homuth G, Hyppönen E, Janssen HL, Johnson

T, Kangas AJ, Kema IP, Kühn JP, Lai S, Lathrop M, Lerch MM, Li Y, Liang TJ, Lin

JP, Loos RJ, Martin NG, Moffatt MF, Montgomery GW, Munroe PB, Musunuru K,

Nakamura Y, O'Donnell CJ, Olafsson I, Penninx BW, Pouta A, Prins BP, Prokopenko

I, Puls R, Ruokonen A, Savolainen MJ, Schlessinger D, Schouten JN, Seedorf U,

Sen-Chowdhry S, Siminovitch KA, Smit JH, Spector TD, Tan W, Teslovich TM,

Tukiainen T, Uitterlinden AG, Van der Klauw MM, Vasan RS, Wallace C,

Wallaschofski H, Wichmann HE, Willemsen G, Würtz P, Xu C, Yerges-Armstrong LM;

Alcohol Genome-wide Association (AlcGen) Consortium; Diabetes Genetics

Replication and Meta-analyses (DIAGRAM+) Study; Genetic Investigation of

Anthropometric Traits (GIANT) Consortium; Global Lipids Genetics Consortium;

Genetics of Liver Disease (GOLD) Consortium; International Consortium for Blood

Pressure (ICBP-GWAS); Meta-analyses of Glucose and Insulin-Related Traits

Consortium (MAGIC), Abecasis GR, Ahmadi KR, Boomsma DI, Caulfield M, Cookson WO,

van Duijn CM, Froguel P, Matsuda K, McCarthy MI, Meisinger C, Mooser V,

Pietiläinen KH, Schumann G, Snieder H, Sternberg MJ, Stolk RP, Thomas HC,

Thorsteinsdottir U, Uda M, Waeber G, Wareham NJ, Waterworth DM, Watkins H,

Whitfield JB, Witteman JC, Wolffenbuttel BH, Fox CS, Ala-Korpela M, Stefansson

K, Vollenweider P, Völzke H, Schadt EE, Scott J, Järvelin MR, Elliott P, Kooner

JS. Genome-wide association study identifies loci influencing concentrations of

liver enzymes in plasma. Nat Genet. 2011 Oct 16;43(11):1131-8. doi:

10.1038/ng.970. PMID: 22001757; PMCID: PMC3482372.

26: Nicholson G, Rantalainen M, Li JV, Maher AD, Malmodin D, Ahmadi KR, Faber

JH, Barrett A, Min JL, Rayner NW, Toft H, Krestyaninova M, Viksna J, Neogi SG,

Dumas ME, Sarkans U; MolPAGE Consortium, Donnelly P, Illig T, Adamski J, Suhre

K, Allen M, Zondervan KT, Spector TD, Nicholson JK, Lindon JC, Baunsgaard D,

Holmes E, McCarthy MI, Holmes CC. A genome-wide metabolic QTL analysis in

Europeans implicates two loci shaped by recent positive selection. PLoS Genet.

2011 Sep;7(9):e1002270. doi: 10.1371/journal.pgen.1002270. Epub 2011 Sep 8.

PMID: 21931564; PMCID: PMC3169529.

27: International Consortium for Blood Pressure Genome-Wide Association Studies,

Ehret GB, Munroe PB, Rice KM, Bochud M, Johnson AD, Chasman DI, Smith AV, Tobin

MD, Verwoert GC, Hwang SJ, Pihur V, Vollenweider P, O'Reilly PF, Amin N, Bragg-

Gresham JL, Teumer A, Glazer NL, Launer L, Zhao JH, Aulchenko Y, Heath S, Sõber

S, Parsa A, Luan J, Arora P, Dehghan A, Zhang F, Lucas G, Hicks AA, Jackson AU,

Peden JF, Tanaka T, Wild SH, Rudan I, Igl W, Milaneschi Y, Parker AN, Fava C,

Chambers JC, Fox ER, Kumari M, Go MJ, van der Harst P, Kao WH, Sjögren M, Vinay

DG, Alexander M, Tabara Y, Shaw-Hawkins S, Whincup PH, Liu Y, Shi G, Kuusisto J,

Tayo B, Seielstad M, Sim X, Nguyen KD, Lehtimäki T, Matullo G, Wu Y, Gaunt TR,

Onland-Moret NC, Cooper MN, Platou CG, Org E, Hardy R, Dahgam S, Palmen J,

Vitart V, Braund PS, Kuznetsova T, Uiterwaal CS, Adeyemo A, Palmas W, Campbell

H, Ludwig B, Tomaszewski M, Tzoulaki I, Palmer ND; CARDIoGRAM consortium; CKDGen

Consortium; KidneyGen Consortium; EchoGen consortium; CHARGE-HF consortium,

Aspelund T, Garcia M, Chang YP, O'Connell JR, Steinle NI, Grobbee DE, Arking DE,

Kardia SL, Morrison AC, Hernandez D, Najjar S, McArdle WL, Hadley D, Brown MJ,

Connell JM, Hingorani AD, Day IN, Lawlor DA, Beilby JP, Lawrence RW, Clarke R,

Hopewell JC, Ongen H, Dreisbach AW, Li Y, Young JH, Bis JC, Kähönen M, Viikari

J, Adair LS, Lee NR, Chen MH, Olden M, Pattaro C, Bolton JA, Köttgen A, Bergmann

S, Mooser V, Chaturvedi N, Frayling TM, Islam M, Jafar TH, Erdmann J, Kulkarni

SR, Bornstein SR, Grässler J, Groop L, Voight BF, Kettunen J, Howard P, Taylor

A, Guarrera S, Ricceri F, Emilsson V, Plump A, Barroso I, Khaw KT, Weder AB,

Hunt SC, Sun YV, Bergman RN, Collins FS, Bonnycastle LL, Scott LJ, Stringham HM,

Peltonen L, Perola M, Vartiainen E, Brand SM, Staessen JA, Wang TJ, Burton PR,

Soler Artigas M, Dong Y, Snieder H, Wang X, Zhu H, Lohman KK, Rudock ME,

Heckbert SR, Smith NL, Wiggins KL, Doumatey A, Shriner D, Veldre G, Viigimaa M,

Kinra S, Prabhakaran D, Tripathy V, Langefeld CD, Rosengren A, Thelle DS, Corsi

AM, Singleton A, Forrester T, Hilton G, McKenzie CA, Salako T, Iwai N, Kita Y,

Ogihara T, Ohkubo T, Okamura T, Ueshima H, Umemura S, Eyheramendy S, Meitinger

T, Wichmann HE, Cho YS, Kim HL, Lee JY, Scott J, Sehmi JS, Zhang W, Hedblad B,

Nilsson P, Smith GD, Wong A, Narisu N, Stančáková A, Raffel LJ, Yao J,

Kathiresan S, O'Donnell CJ, Schwartz SM, Ikram MA, Longstreth WT Jr, Mosley TH,

Seshadri S, Shrine NR, Wain LV, Morken MA, Swift AJ, Laitinen J, Prokopenko I,

Zitting P, Cooper JA, Humphries SE, Danesh J, Rasheed A, Goel A, Hamsten A,

Watkins H, Bakker SJ, van Gilst WH, Janipalli CS, Mani KR, Yajnik CS, Hofman A,

Mattace-Raso FU, Oostra BA, Demirkan A, Isaacs A, Rivadeneira F, Lakatta EG,

Orru M, Scuteri A, Ala-Korpela M, Kangas AJ, Lyytikäinen LP, Soininen P,

Tukiainen T, Würtz P, Ong RT, Dörr M, Kroemer HK, Völker U, Völzke H, Galan P,

Hercberg S, Lathrop M, Zelenika D, Deloukas P, Mangino M, Spector TD, Zhai G,

Meschia JF, Nalls MA, Sharma P, Terzic J, Kumar MV, Denniff M, Zukowska-

Szczechowska E, Wagenknecht LE, Fowkes FG, Charchar FJ, Schwarz PE, Hayward C,

Guo X, Rotimi C, Bots ML, Brand E, Samani NJ, Polasek O, Talmud PJ, Nyberg F,

Kuh D, Laan M, Hveem K, Palmer LJ, van der Schouw YT, Casas JP, Mohlke KL,

Vineis P, Raitakari O, Ganesh SK, Wong TY, Tai ES, Cooper RS, Laakso M, Rao DC,

Harris TB, Morris RW, Dominiczak AF, Kivimaki M, Marmot MG, Miki T, Saleheen D,

Chandak GR, Coresh J, Navis G, Salomaa V, Han BG, Zhu X, Kooner JS, Melander O,

Ridker PM, Bandinelli S, Gyllensten UB, Wright AF, Wilson JF, Ferrucci L,

Farrall M, Tuomilehto J, Pramstaller PP, Elosua R, Soranzo N, Sijbrands EJ,

Altshuler D, Loos RJ, Shuldiner AR, Gieger C, Meneton P, Uitterlinden AG,

Wareham NJ, Gudnason V, Rotter JI, Rettig R, Uda M, Strachan DP, Witteman JC,

Hartikainen AL, Beckmann JS, Boerwinkle E, Vasan RS, Boehnke M, Larson MG,

Järvelin MR, Psaty BM, Abecasis GR, Chakravarti A, Elliott P, van Duijn CM,

Newton-Cheh C, Levy D, Caulfield MJ, Johnson T. Genetic variants in novel

pathways influence blood pressure and cardiovascular disease risk. Nature. 2011

Sep 11;478(7367):103-9. doi: 10.1038/nature10405. PMID: 21909115; PMCID:

PMC3340926.

28: Wain LV, Verwoert GC, O'Reilly PF, Shi G, Johnson T, Johnson AD, Bochud M,

Rice KM, Henneman P, Smith AV, Ehret GB, Amin N, Larson MG, Mooser V, Hadley D,

Dörr M, Bis JC, Aspelund T, Esko T, Janssens AC, Zhao JH, Heath S, Laan M, Fu J,

Pistis G, Luan J, Arora P, Lucas G, Pirastu N, Pichler I, Jackson AU, Webster

RJ, Zhang F, Peden JF, Schmidt H, Tanaka T, Campbell H, Igl W, Milaneschi Y,

Hottenga JJ, Vitart V, Chasman DI, Trompet S, Bragg-Gresham JL, Alizadeh BZ,

Chambers JC, Guo X, Lehtimäki T, Kühnel B, Lopez LM, Polašek O, Boban M, Nelson

CP, Morrison AC, Pihur V, Ganesh SK, Hofman A, Kundu S, Mattace-Raso FU,

Rivadeneira F, Sijbrands EJ, Uitterlinden AG, Hwang SJ, Vasan RS, Wang TJ,

Bergmann S, Vollenweider P, Waeber G, Laitinen J, Pouta A, Zitting P, McArdle

WL, Kroemer HK, Völker U, Völzke H, Glazer NL, Taylor KD, Harris TB, Alavere H,

Haller T, Keis A, Tammesoo ML, Aulchenko Y, Barroso I, Khaw KT, Galan P,

Hercberg S, Lathrop M, Eyheramendy S, Org E, Sõber S, Lu X, Nolte IM, Penninx

BW, Corre T, Masciullo C, Sala C, Groop L, Voight BF, Melander O, O'Donnell CJ,

Salomaa V, d'Adamo AP, Fabretto A, Faletra F, Ulivi S, Del Greco F, Facheris M,

Collins FS, Bergman RN, Beilby JP, Hung J, Musk AW, Mangino M, Shin SY, Soranzo

N, Watkins H, Goel A, Hamsten A, Gider P, Loitfelder M, Zeginigg M, Hernandez D,

Najjar SS, Navarro P, Wild SH, Corsi AM, Singleton A, de Geus EJ, Willemsen G,

Parker AN, Rose LM, Buckley B, Stott D, Orru M, Uda M; LifeLines Cohort Study,

van der Klauw MM, Zhang W, Li X, Scott J, Chen YD, Burke GL, Kähönen M, Viikari

J, Döring A, Meitinger T, Davies G, Starr JM, Emilsson V, Plump A, Lindeman JH,

Hoen PA, König IR; EchoGen consortium, Felix JF, Clarke R, Hopewell JC, Ongen H,

Breteler M, Debette S, Destefano AL, Fornage M; AortaGen Consortium, Mitchell

GF; CHARGE Consortium Heart Failure Working Group, Smith NL; KidneyGen

consortium, Holm H, Stefansson K, Thorleifsson G, Thorsteinsdottir U; CKDGen

consortium; Cardiogenics consortium; CardioGram, Samani NJ, Preuss M, Rudan I,

Hayward C, Deary IJ, Wichmann HE, Raitakari OT, Palmas W, Kooner JS, Stolk RP,

Jukema JW, Wright AF, Boomsma DI, Bandinelli S, Gyllensten UB, Wilson JF,

Ferrucci L, Schmidt R, Farrall M, Spector TD, Palmer LJ, Tuomilehto J, Pfeufer

A, Gasparini P, Siscovick D, Altshuler D, Loos RJ, Toniolo D, Snieder H, Gieger

C, Meneton P, Wareham NJ, Oostra BA, Metspalu A, Launer L, Rettig R, Strachan

DP, Beckmann JS, Witteman JC, Erdmann J, van Dijk KW, Boerwinkle E, Boehnke M,

Ridker PM, Jarvelin MR, Chakravarti A, Abecasis GR, Gudnason V, Newton-Cheh C,

Levy D, Munroe PB, Psaty BM, Caulfield MJ, Rao DC, Tobin MD, Elliott P, van

Duijn CM. Genome-wide association study identifies six new loci influencing

pulse pressure and mean arterial pressure. Nat Genet. 2011 Sep

11;43(10):1005-11. doi: 10.1038/ng.922. PMID: 21909110; PMCID: PMC3445021.

29: Nicholson G, Rantalainen M, Maher AD, Li JV, Malmodin D, Ahmadi KR, Faber

JH, Hallgrímsdóttir IB, Barrett A, Toft H, Krestyaninova M, Viksna J, Neogi SG,

Dumas ME, Sarkans U, The Molpage Consortium, Silverman BW, Donnelly P, Nicholson

JK, Allen M, Zondervan KT, Lindon JC, Spector TD, McCarthy MI, Holmes E,

Baunsgaard D, Holmes CC. Human metabolic profiles are stably controlled by

genetic and environmental variation. Mol Syst Biol. 2011 Aug 30;7:525. doi:

10.1038/msb.2011.57. PMID: 21878913; PMCID: PMC3202796.

30: Min JL, Taylor JM, Richards JB, Watts T, Pettersson FH, Broxholme J, Ahmadi

KR, Surdulescu GL, Lowy E, Gieger C, Newton-Cheh C, Perola M, Soranzo N, Surakka

I, Lindgren CM, Ragoussis J, Morris AP, Cardon LR, Spector TD, Zondervan KT. The

use of genome-wide eQTL associations in lymphoblastoid cell lines to identify

novel genetic pathways involved in complex traits. PLoS One. 2011;6(7):e22070.

doi: 10.1371/journal.pone.0022070. Epub 2011 Jul 15. PMID: 21789213; PMCID:

PMC3137612.

31: Rahmioglu N, Heaton J, Clement G, Gill R, Surdulescu G, Zlobecka K, Hodgkiss

D, Ma Y, Hider RC, Smith NW, Ahmadi KR. Genetic epidemiology of induced CYP3A4

activity. Pharmacogenet Genomics. 2011 Oct;21(10):642-51. doi:

10.1097/FPC.0b013e3283498ecf. PMID: 21750469.

32: Ahmadi KR. Role of common genetic variants on the risk of Stevens-Johnson

syndrome and toxic epidermal necrolysis. Pharmacogenomics. 2011 Jun;12(6):761-4.

doi: 10.2217/pgs.11.39. PMID: 21692608.

33: Cotlarciuc I, Andrew T, Dew T, Clement G, Gill R, Surdulescu G, Sherwood R,

Ahmadi KR. The basis of differential responses to folic acid supplementation. J

Nutrigenet Nutrigenomics. 2011;4(2):99-109. doi: 10.1159/000327768. Epub 2011

May 28. PMID: 21625172.

34: Small KS, Hedman AK, Grundberg E, Nica AC, Thorleifsson G, Kong A,

Thorsteindottir U, Shin SY, Richards HB; GIANT Consortium; MAGIC Investigators;

DIAGRAM Consortium, Soranzo N, Ahmadi KR, Lindgren CM, Stefansson K, Dermitzakis

ET, Deloukas P, Spector TD, McCarthy MI; MuTHER Consortium. Identification of an

imprinted master trans regulator at the KLF14 locus related to multiple

metabolic phenotypes. Nat Genet. 2011 Jun;43(6):561-4. doi: 10.1038/ng.833. Epub

2011 May 15. Erratum in: Nat Genet. 2011 Oct;43(10):1040. PMID: 21572415; PMCID:

PMC3192952.

35: Rahmioglu N, Le Gall G, Heaton J, Kay KL, Smith NW, Colquhoun IJ, Ahmadi KR,

Kemsley EK. Prediction of variability in CYP3A4 induction using a combined 1H

NMR metabonomics and targeted UPLC-MS approach. J Proteome Res. 2011 Jun

3;10(6):2807-16. doi: 10.1021/pr200077n. Epub 2011 Apr 27. PMID: 21491888.

36: Heaton J, Rahmioglu N, Ahmadi KR, Legido-Quigley C, Smith NW. Rapid

quantification of quinine and its major metabolite (3S)-3-hydroxyquinine in

diluted urine by UPLC-MS/MS. J Pharm Biomed Anal. 2011 Jun 1;55(3):494-9. doi:

10.1016/j.jpba.2011.02.004. Epub 2011 Mar 5. PMID: 21377309.

37: Chambers JC, Zhang W, Lord GM, van der Harst P, Lawlor DA, Sehmi JS, Gale

DP, Wass MN, Ahmadi KR, Bakker SJ, Beckmann J, Bilo HJ, Bochud M, Brown MJ,

Caulfield MJ, Connell JM, Cook HT, Cotlarciuc I, Davey Smith G, de Silva R, Deng

G, Devuyst O, Dikkeschei LD, Dimkovic N, Dockrell M, Dominiczak A, Ebrahim S,

Eggermann T, Farrall M, Ferrucci L, Floege J, Forouhi NG, Gansevoort RT, Han X,

Hedblad B, Homan van der Heide JJ, Hepkema BG, Hernandez-Fuentes M, Hypponen E,

Johnson T, de Jong PE, Kleefstra N, Lagou V, Lapsley M, Li Y, Loos RJ, Luan J,

Luttropp K, Maréchal C, Melander O, Munroe PB, Nordfors L, Parsa A, Peltonen L,

Penninx BW, Perucha E, Pouta A, Prokopenko I, Roderick PJ, Ruokonen A, Samani

NJ, Sanna S, Schalling M, Schlessinger D, Schlieper G, Seelen MA, Shuldiner AR,

Sjögren M, Smit JH, Snieder H, Soranzo N, Spector TD, Stenvinkel P, Sternberg

MJ, Swaminathan R, Tanaka T, Ubink-Veltmaat LJ, Uda M, Vollenweider P, Wallace

C, Waterworth D, Zerres K, Waeber G, Wareham NJ, Maxwell PH, McCarthy MI,

Jarvelin MR, Mooser V, Abecasis GR, Lightstone L, Scott J, Navis G, Elliott P,

Kooner JS. Genetic loci influencing kidney function and chronic kidney disease.

Nat Genet. 2010 May;42(5):373-5. doi: 10.1038/ng.566. Epub 2010 Apr 11. PMID:

20383145; PMCID: PMC3748585.

38: Rahmioğlu N, Ahmadi KR. Classical twin design in modern pharmacogenomics

studies. Pharmacogenomics. 2010 Feb;11(2):215-26. doi: 10.2217/pgs.09.171. PMID:

20136360.

39: Soranzo N, Rivadeneira F, Chinappen-Horsley U, Malkina I, Richards JB,

Hammond N, Stolk L, Nica A, Inouye M, Hofman A, Stephens J, Wheeler E, Arp P,

Gwilliam R, Jhamai PM, Potter S, Chaney A, Ghori MJ, Ravindrarajah R, Ermakov S,

Estrada K, Pols HA, Williams FM, McArdle WL, van Meurs JB, Loos RJ, Dermitzakis

ET, Ahmadi KR, Hart DJ, Ouwehand WH, Wareham NJ, Barroso I, Sandhu MS, Strachan

DP, Livshits G, Spector TD, Uitterlinden AG, Deloukas P. Meta-analysis of

genome-wide scans for human adult stature identifies novel Loci and associations

with measures of skeletal frame size. PLoS Genet. 2009 Apr;5(4):e1000445. doi:

10.1371/journal.pgen.1000445. Epub 2009 Apr 3. PMID: 19343178; PMCID:

PMC2661236.

40: McEvoy BP, Montgomery GW, McRae AF, Ripatti S, Perola M, Spector TD, Cherkas

L, Ahmadi KR, Boomsma D, Willemsen G, Hottenga JJ, Pedersen NL, Magnusson PK,

Kyvik KO, Christensen K, Kaprio J, Heikkilä K, Palotie A, Widen E, Muilu J,

Syvänen AC, Liljedahl U, Hardiman O, Cronin S, Peltonen L, Martin NG, Visscher

PM. Geographical structure and differential natural selection among North

European populations. Genome Res. 2009 May;19(5):804-14. doi:

10.1101/gr.083394.108. Epub 2009 Mar 5. PMID: 19265028; PMCID: PMC2675969.

41: Rahmioglu N, Andrew T, Cherkas L, Surdulescu G, Swaminathan R, Spector T,

Ahmadi KR. Epidemiology and genetic epidemiology of the liver function test

proteins. PLoS One. 2009;4(2):e4435. doi: 10.1371/journal.pone.0004435. Epub

2009 Feb 11. PMID: 19209234; PMCID: PMC2636884.

42: Crockford DJ, Maher AD, Ahmadi KR, Barrett A, Plumb RS, Wilson ID, Nicholson

JK. 1H NMR and UPLC-MS(E) statistical heterospectroscopy: characterization of

drug metabolites (xenometabolome) in epidemiological studies. Anal Chem. 2008

Sep 15;80(18):6835-44. doi: 10.1021/ac801075m. Epub 2008 Aug 14. Erratum in:

Anal Chem. 2008 Nov 1;80(21):8353. PMID: 18700783.

43: Richards JB, Rivadeneira F, Inouye M, Pastinen TM, Soranzo N, Wilson SG,

Andrew T, Falchi M, Gwilliam R, Ahmadi KR, Valdes AM, Arp P, Whittaker P,

Verlaan DJ, Jhamai M, Kumanduri V, Moorhouse M, van Meurs JB, Hofman A, Pols HA,

Hart D, Zhai G, Kato BS, Mullin BH, Zhang F, Deloukas P, Uitterlinden AG,

Spector TD. Bone mineral density, osteoporosis, and osteoporotic fractures: a

genome-wide association study. Lancet. 2008 May 3;371(9623):1505-12. doi:

10.1016/S0140-6736(08)60599-1. PMID: 18455228; PMCID: PMC2679414.

44: Chinappen-Horsley U, Blake GM, Fogelman I, Kato B, Ahmadi KR, Spector TD.

Quantitative trait loci for bone lengths on chromosome 5 using dual energy X-Ray

absorptiometry imaging in the Twins UK cohort. PLoS One. 2008 Mar 12;3(3):e1752.

doi: 10.1371/journal.pone.0001752. PMID: 18335030; PMCID: PMC2262137.

45: Zhang F, Kato BS, Gardner JP, Kimura M, Spector TD, Ahmadi KR. Lack of

association between leukocyte telomere length and genetic variants in two

ageing-related candidate genes. Mech Ageing Dev. 2007 Jul-Aug;128(7-8):415-22.

doi: 10.1016/j.mad.2007.05.007. Epub 2007 May 25. PMID: 17624411.

46: Zhang F, Zhai G, Kato BS, Hart DJ, Hunter D, Spector TD, Ahmadi KR.

Association between KLOTHO gene and hand osteoarthritis in a female Caucasian

population. Osteoarthritis Cartilage. 2007 Jun;15(6):624-9. doi:

10.1016/j.joca.2006.12.002. Epub 2007 Jan 30. PMID: 17270470.

47: Healy DG, Abou-Sleiman PM, Ahmadi KR, Gandhi S, Muqit MM, Bhatia KP, Quinn

NP, Lees AJ, Holton JL, Revesz T, Wood NW. NR4A2 genetic variation in sporadic

Parkinson's disease: a genewide approach. Mov Disord. 2006 Nov;21(11):1960-3.

doi: 10.1002/mds.21018. PMID: 16977628.

48: Need AC, Ahmadi KR, Spector TD, Goldstein DB. Obesity is associated with

genetic variants that alter dopamine availability. Ann Hum Genet. 2006 May;70(Pt

3):293-303. doi: 10.1111/j.1529-8817.2005.00228.x. PMID: 16674552.

49: Spector TD, Ahmadi KR, Valdes AM. When is a replication not a replication?

Or how to spot a good genetic association study. Arthritis Rheum. 2006

Apr;54(4):1051-4. doi: 10.1002/art.21730. PMID: 16572439.

50: Shah PR, Ahmad-Annuar A, Ahmadi KR, Russ C, Sapp PC, Horvitz HR, Brown RH

Jr, Goldstein DB, Fisher EM. No association of DYNC1H1 with sporadic ALS in a

case-control study of a northern European derived population: a tagging SNP

approach. Amyotroph Lateral Scler. 2006 Mar;7(1):46-56. doi:

10.1080/14660820500397057. PMID: 16546759.

51: Ozawa T, Healy DG, Abou-Sleiman PM, Ahmadi KR, Quinn N, Lees AJ, Shaw K,

Wullner U, Berciano J, Moller JC, Kamm C, Burk K, Josephs KA, Barone P, Tolosa

E, Goldstein DB, Wenning G, Geser F, Holton JL, Gasser T, Revesz T, Wood NW;

European MSA study group. The alpha-synuclein gene in multiple system atrophy. J

Neurol Neurosurg Psychiatry. 2006 Apr;77(4):464-7. doi:

10.1136/jnnp.2005.073528. PMID: 16543523; PMCID: PMC2077505.

52: Healy DG, Abou-Sleiman PM, Casas JP, Ahmadi KR, Lynch T, Gandhi S, Muqit MM,

Foltynie T, Barker R, Bhatia KP, Quinn NP, Lees AJ, Gibson JM, Holton JL, Revesz

T, Goldstein DB, Wood NW. UCHL-1 is not a Parkinson's disease susceptibility

gene. Ann Neurol. 2006 Apr;59(4):627-33. doi: 10.1002/ana.20757. PMID: 16450370.

53: Healy DG, Abou-Sleiman PM, Quinn N, Ahmadi KR, Ozawa T, Kamm C, Wullner U,

Oertel WH, Burk K, Dupont E, Pellecchia MT, Tolosa E, Gasser T, Holton JL,

Revesz T, Goldstein DB, Lees AJ, Wood NW; European MSA Study Group. UCHL-1 gene

in multiple system atrophy: a haplotype tagging approach. Mov Disord. 2005

Oct;20(10):1338-43. doi: 10.1002/mds.20575. PMID: 16007636.

54: Ahmadi KR, Weale ME, Xue ZY, Soranzo N, Yarnall DP, Briley JD, Maruyama Y,

Kobayashi M, Wood NW, Spurr NK, Burns DK, Roses AD, Saunders AM, Goldstein DB. A

single-nucleotide polymorphism tagging set for human drug metabolism and

transport. Nat Genet. 2005 Jan;37(1):84-9. doi: 10.1038/ng1488. Epub 2004 Dec

19. PMID: 15608640.

55: Healy DG, Abou-Sleiman PM, Ahmadi KR, Muqit MM, Bhatia KP, Quinn NP, Lees

AJ, Latchmann DS, Goldstein DB, Wood NW. The gene responsible for PARK6

Parkinson's disease, PINK1, does not influence common forms of parkinsonism. Ann

Neurol. 2004 Sep;56(3):329-35. doi: 10.1002/ana.20206. PMID: 15349859.

56: Goldstein DB, Cavalleri GL, Ahmadi KR. The genetics of common diseases: 10

million times as hard. Cold Spring Harb Symp Quant Biol. 2003;68:395-401. doi:

10.1101/sqb.2003.68.395. PMID: 15338641.

57: Healy DG, Abou-Sleiman PM, Jain S, Ahmadi KR, Wood NW. Assessment of a DJ-1

(PARK7) polymorphism in Finnish PD. Neurology. 2004 Jun 22;62(12):2335. doi:

10.1212/wnl.62.12.2335-a. PMID: 15210917.

58: Healy DG, Abou-Sleiman PM, Ozawa T, Lees AJ, Bhatia K, Ahmadi KR, Wullner U,

Berciano J, Moller JC, Kamm C, Burk K, Barone P, Tolosa E, Quinn N, Goldstein

DB, Wood NW. A functional polymorphism regulating dopamine beta-hydroxylase

influences against Parkinson's disease. Ann Neurol. 2004 Mar;55(3):443-6. doi:

10.1002/ana.20063. Erratum in: Ann Neurol. 2004 Aug;56(2):311. Barrone P

[corrected to Barone P]. PMID: 14991826.

59: Goldstein DB, Ahmadi KR, Weale ME, Wood NW. Genome scans and candidate gene

approaches in the study of common diseases and variable drug responses. Trends

Genet. 2003 Nov;19(11):615-22. doi: 10.1016/j.tig.2003.09.006. PMID: 14585613.

60: Ahmadi KR, Lanchbury JS, Reed P, Chiano M, Thompson D, Galley M, Line A,

Lank E, Wong HJ, Strachan D, Spector TD. Novel association suggests multiple

independent QTLs within chromosome 5q21-33 region control variation in total

humans IgE levels. Genes Immun. 2003 Jun;4(4):289-97. doi:

10.1038/sj.gene.6363968. PMID: 12761566.

61: Ahmadi KR, Goldstein DB. Multifactorial diseases: asthma genetics point the

way. Curr Biol. 2002 Oct 15;12(20):R702-4. doi: 10.1016/s0960-9822(02)01211-3.

PMID: 12401189.

62: Ahmadi KR, Hall MA, Norman P, Vaughan RW, Snieder H, Spector TD, Lanchbury

JS. Genetic determinism in the relationship between human CD4+ and CD8+ T

lymphocyte populations? Genes Immun. 2001 Nov;2(7):381-7. doi:

10.1038/sj.gene.6363796. PMID: 11704804.

63: Hall MA, Ahmadi KR, Norman P, Snieder H, MacGregor AJ, Vaughan RW, Spector

TD, Lanchbury JS. Genetic influence on peripheral blood T lymphocyte levels.

Genes Immun. 2000 Oct;1(7):423-7. doi: 10.1038/sj.gene.6363702. PMID: 11196672.