Development and use of new and derived data to facilitate the optimisation and evaluation of breast screening AI tools

A 4-year, fully funded (tuition fees and stipend) project commencing in October 2022. This PhD studentship its funded by the University of Surrey Physics PhD programme, and is a collaboration between the University of Surrey, the National Physical Laboratory (NPL) and the Royal Surrey NHS Foundation Trust (RSNFT).

Start date
1 July 2022
Application deadline
Funding source
The University of Surrey (matched iCase studentship)
Funding information
  • The studentship is fully funded by University of Surrey
  • Stipend: £15,609/year plus living allowance top up of £2,200/year (Total: £17,809/year)
  • The studentship also covers the tuition fee at the home rate (£4,500/year) and additional funds are available for training, and travel costs for visits to NPL, other project partners and academic conferences.

About

Artificial Intelligence (AI) tools for diagnosis of cancer on breast screening images are becoming available. It is vital that these tools are able to be applied and effective in any setting across the UK and must be adaptable to varying populations, manufacturers, image processing and varying image acquisition techniques. It is therefore important that appropriately diverse and representative training and validation datasets are available. This can be achieved through the large-scale collection of de-identified data from large numbers of sites, and this is what the OPTIMAM Mammographic Image Database (OMI-DB) (containing 3.5 million images from over 200,000 women) is attempting to achieve. However, there are additional techniques that can be applied to supplement this dataset, enriching it so that it can be used to improve and optimise AI tools.

This PhD project will use techniques to alter an unprocessed image to make it appear as if it was captured with lower dose or different beam quality or x-ray detector, or processed using different manufactures image processing software to generate additional data to supplement OMI-DB. It will also develop image processing software to understand the effect of this on the images that are used for AI tool development. This project will involve the use of this data to investigate and evaluate how varying factors in the images may confound or affect an AI tools performance. This will involve retraining in-house algorithms and subsequent validation to evaluate the resulting effects that varying the training and validation datasets have.  Is it anticipated that in addition to the use of in-house or open-source algorithms the project will involve utilising the groups' existing collaboration with Google Health to investigate these same factors in the Google Health Breast AI tool.

This project will develop physics-based methodology to derive new data to assess AI based tools for medical imaging. This requires the development of new knowledge and fundamental research in a way which is well-suited to a PhD project. The project brings together metrological analysis and data science skills with medical imaging, and involves working with specialists from several different disciplines, preparing the candidate for a career in either medical research or data-intensive metrology.

The project is a collaboration between the University of Surrey (Radiation and Medical Physics Group), the National Physical Laboratory (Data Science and Medical Physics) and the Royal Surrey NHS Foundation Trust (Scientific Computing). The student will be predominately based at the University of Surrey and RSNFT with possibility of placements at NPL for up to 3 months a year.

Related links
Radiation and Medical Physics Group NPL Scientific Computing OPTIMAM Mammography Image Database (OMI-DB)
Main supervision team:
  • Prof Rebecca Nutbrown, University of Surrey and Royal Surrey NHS Foundation Trust
  • Dr Nadia Smith, NPL Data Science and Royal Surrey NHS Foundation Trust
  • Dr Mark Halling-Brown, Royal Surrey NHS Foundation Trust and Visiting Professor at the University of Surrey
  • Dr Lucy Warren, Royal Surrey NHS Foundation Trust

Eligibility criteria

UK applicants who hold a First or 2:1 UK honours degree in a relevant subject area, or a 2:2 alongside a good masters degree (a distinction is usually required).

English language requirements: If English is not your first language, you will be required to have an IELTS Academic of 6.5 or above (or equivalent), with no sub-test score below 6.

How to apply

Applications should be submitted via the Physics PhD programme page on the "Apply" tab. Please clearly state the studentship title and supervisor on your application.


Application deadline

Contact details

Rebecca Nutbrown
E-mail: r.nutbrown@surrey.ac.uk
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