Dr Huggett read genetics in Liverpool University followed by a PhD in Cardiff University where he studied the potential role of mechanically regulated genes in bone remodeling. Particularly interested in the application of advanced molecular methods to clinical scenarios he moved to UCL in 2002 to take up a Senior Research Fellow position with Professor Alimuddin Zumla. Here he investigated approaches to diagnose infectious diseases in developing world settings before moving to LGC in 2009. At LGC, which is the UK's designated national measurement institute role for chemical and bio-analytical measurement, he has led a large number of molecular diagnostics, genomics and nucleic acid research projects. This work focuses on high accuracy measurement as well as strengthening the traceability of measurements that underpin legislation, regulation and standardisation. In 2016 Dr Huggett joined the University of Surrey while retaining a joint appointment with LGC, where his focus is on analytical microbiology and diagnosis of infectious diseases.
Molecular diagnosis and routes to support translation of preclinical methods to patient care. My interest are in applying the concepts of metrology (the science of measurement) to improve accuracy and reproducibility of molecular analysis and this has enabled me to investigate a wide range of fascinating subjects ranging from pathogen identification and genotyping to the detection of surrogate markers of infection. Research has investigated methodologies ranging from high throughput centralised approaches to point of care.
Main internal collaboratorsProfessor Graham StewartDr Jose JimenezDr Emma LaingProfessor David BlackbournProfessor Mike Taylor
Main External Collaborators• Professor Stephen Bustin, Anglia Ruskin University, http://www.anglia.ac.uk/medical-science/about/our-staff/stephen-bustin• Professor Taane Clark, LSHTM http://www.lshtm.ac.uk/aboutus/people/clark.taane• Dr Vladimir Benes, EMBL http://www.embl.de/services/core_facilities/genecore/members/index.php?s_personId=CP-60003318• Dr Jeremy Garson, University College London https://iris.ucl.ac.uk/iris/browse/profile?upi=JAGAR94• Dr Kathryn Harris, Great Ormond Street Hospital http://www.labs.gosh.nhs.uk/research/microbiology-virology• Professor Tim McHugh, University College London http://www.ucl.ac.uk/infection-immunity/research/res_ccm• Professor Martin Taylor, MRC Human Genetics Unit MRC IGMM http://www.hgu.mrc.ac.uk/people/taylor.html
Principal Investigator of the AntiMicroResist consortium https://www.euramet.org/research-innovation/search-research-projects/details/?eurametCtcp_project_show%5Bproject%5D=1421&eurametCtcp_project%5Bback%5D=831&cHash=734440252cd62064b7857441e6a1fe4c
Committee membershipGenetics Society, http://www.genetics.org.ukCCQM-NAWG, http://www.bipm.org/en/committees/cc/wg/nawg.html
Society membershipsESGMD (ESCMID), https://www.escmid.org/index.php?id=151RSTMH https://rstmh.orgComMet
Principal Scientist at LGC http://www.lgcgroup.comManaging editor of BDQ http://www.journals.elsevier.com/biomolecular-detection-and-quantification