My research project
Hunting for bladder carcinogens
Epidemiological studies have shown long-term consumption of chlorinated drinking water is associated with an enhanced risk of developing bladder cancer. The cause of this link remains obscure, although it is assumed that disinfection by-products are implicated. These are generated during drinking water treatment from reactions between precursor compounds (both organic and inorganic) and disinfectants (chlorine being the commonest). Many hundreds of disinfection by-products are known to occur in drinking water, which reflects both precursor diversity and the complexity of the chemistry involved. However, the identity of the disinfection by-products responsible for increasing the risk of bladder cancer remain unknown. Thus, there is a mismatch between the evidence from analytical chemistry, toxicology and epidemiology. A plausible explanation is that bladder carcinogens in drinking water are being missed or overlooked. This research aims at identifying and prioritising DBPs that may be responsible for the risk of bladder cancer observed, the carcinogenicity of which can be assessed in future work.
Comparison of advanced oxidation processes for metaldehyde removal and downstream disinfection by-product formation.
Project sponsored by Severn Trent Water
Specialisation in environmental and analytical chemistry
Affiliations and memberships
Occurrence, toxicity and removal of micropollutants in drinking water
- ENG1077 - Integrated design: AutoCAD tutorials
- CHE1044 - Principles of analytical chemistry: Lab demonstrations
- CHE1043 - Physical processes in chemistry: Lab demonstrations