Dr Natalie Belsey CChem FRSC
Associate Professor & Principal Scientist at NPL
MChem, DPhil
About
Biography
Natalie Belsey is an Associate Professor in the School of Chemistry and Chemical Engineering at Surrey, and a Principal Scientist in the Surface Technology Group at NPL. Natalie graduated with MChem in 2005 from Lincoln College, Oxford, where she remained for her DPhil in protein film electrochemistry under the supervision of Prof Fraser Armstrong FRS. In 2009, she joined the University of Bath for postdoctoral research in the group of Prof Richard Guy, initially investigating the percutaneous absorption of pesticide residues and subsequently imaging transdermal drug delivery with SRS, CARS and two photon fluorescence microscopies in collaboration with the University of Exeter. Natalie is a Fellow of the Royal Society of Chemistry, a Chartered Chemist and a Fellow of the Community for Analytical Measurement Science (CAMS).
Areas of specialism
Raman spectroscopy; Stimulated Raman scattering (SRS) microscopy; Topical drug delivery; Formulated product characterisation; Nanomaterial characterisation ; Skin imaging ; Dermal absoption
Affiliations and memberships
CChem
Chartered Chemist
ResearchResearch interests
Natalie's research focuses on the use of Raman and non-linear optical spectroscopies, in particular stimulated Raman scattering (SRS) microscopy. Her research interests include the characterisation of formulated products (including nanocarriers), and their fate post-application to the skin.
Research interests
Natalie's research focuses on the use of Raman and non-linear optical spectroscopies, in particular stimulated Raman scattering (SRS) microscopy. Her research interests include the characterisation of formulated products (including nanocarriers), and their fate post-application to the skin.
Publications
T. Sainsbury, S. Gnaniah, S. J. Spencer, S. Mignuzzi, N. A. Belsey, K. R. Paton, A. Satti. (2017) Extreme mechanical reinforcement in graphene oxide based thin-film nanocomposites via covalently tailored nanofiller matrix compatibilization
B. Brennan, S. J. Spencer, N. A. Belsey, T. Faris, H. Cronin, S. R. P. Silva, T. Sainsbury, I. S. Gilmore, Z. Stoeva, A. J. Pollard (2017) Structural, Chemical and Electrical Characterisation of Conductive Graphene-Polymer Composite Films
N.A. Belsey et al (2016) Versailles project on advanced materials and standards interlaboratory study on measuring the thickness and chemistry of nanoparticle coatings using XPS and LEIS
N. A. Belsey, A. G. Shard, and C. Minelli (2015) Analysis of protein coatings on gold nanoparticles by XPS and liquid-based particle sizing techniques.
N. A. Belsey, A. G. Shard, and C. Minelli (2016) Surface Chemistry in 'Nanomaterial Characterisation: An Introduction'. Edited by R. Tantra. Wiley, 2016. Chapter 8, 153-178.
W. S. Chiu, N. A. Belsey, N. L. Garrett, J. Moger, G. J. Price, M. B. Delgado-Charro, R. H. Guy. (2015) Drug delivery into microneedle-porated nails from nanoparticle reservoirs
W. S. Chiu, N. A. Belsey, N. L. Garrett, J. Moger, M. B. Delgado-Charro, and R. H. Guy. (2015) Molecular diffusion in the human nail measured by stimulated Raman scattering microscopy
N. A. Belsey, L. R. Contreras-Rojas, N. L. Garrett, A. J. Pickup-Gerlaugh, G. J. Price, J. Moger, and R. H. Guy. (2014) Evaluation of drug delivery to intact and porated skin by coherent Raman scattering and fluorescence microscopies.
N. A. Belsey, S. F. Cordery, A. L. Bunge, and R. H. Guy. (2011) Assessment of dermal exposure to pesticide residues during re-entry
N. A. Belsey, L. R. Contreras-Rojas, and R. H. Guy (2014) 'Imaging drug delivery to skin with coherent Raman scattering microscopy' in 'Non Invasive Diagnostic Techniques in Clinical Dermatology'. Edited by E. Berardesca, H. Maibach and K. P. Wilhelm. Springer
F. A. Armstrong, N. A. Belsey, J. A. Cracknell, G. Goldet, A. Parkin, E. Reisner, K. A. Vincent and A. F. Wait (2009) Dynamic electrochemical investigations of hydrogen oxidation and production by enzymes and implications for future technology.
K. A. Vincent, X. Li, C. F. Blanford, N. A. Belsey, J. H. Weiner, and F. A. Armstrong. (2007) Enzymatic catalysis on conducting graphite particles
K. A. Vincent, N. A. Belsey, W. Lubitz, and F. A. Armstrong (2006) Rapid and reversible reactions of [NiFe]-hydrogenases with sulfide
A. Dexter, D. Tsikritsis, N. A. Belsey, S. A. Thomas, J. Venton, J. Bunch, M. Romanchikova (2022) Next generation digital pathology: emerging trends and measurement challenges for molecular pathology
A. J. Taylor, D. Tsikritsis, A. Dexter, A. Burton, J. Bunch, N. A. Belsey (2022) Classification of tablet formulations by desorption electrospray ionisation mass spectrometry and transmission Raman spectroscopy
D. Tsikritsis, E. J. Legge, N. A. Belsey (2022) Practical considerations for quantitative and reproducible measurements with stimulated Raman scattering microscopy
M. A. M. Tabosa, P. Vitry, P. Zarmpi, A. L. Bunge, N. A. Belsey, D. Tsikritsis, T. J Woodman, K. A. J. White, M. B. Delgado-Charro, R. H. Guy (2023) Quantification of Chemical Uptake into the Skin by Vibrational Spectroscopies and Stratum Corneum Sampling
A. Goel, D. Tsikritsis, N. A. Belsey, R. Pendlington, S. Glavin, T. Chen (2023) Measurement of chemical penetration in skin using Stimulated Raman scattering microscopy and multivariate curve resolution-alternating least squares
P. Zarmpi, M. A. M. Tabosa, P. Vitry, A. L. Bunge, N. A. Belsey, D. Tsikritsis, T. J. Woodman, M. B. Delgado-Charro, R. H. Guy (2023) Confocal Raman Spectroscopic Characterization of Dermatopharmacokinetics Ex Vivo
N. A. Belsey, A. Dexter, J-L. Vorng, D. Tsikritsis, C. J. Nikula, T. Murta, M-V. Tiddia, J. Zhang, E. Gurdak, G. F. Trindade, I. S. Gilmore, L. Page, C. S. Roper, R. H. Guy, M. Boncheva Bettex (2023) Visualisation of drug distribution in skin using correlative optical spectroscopy and mass spectrometry imaging
N. A. Belsey, V. Tyagi, J-L. Vorng, A. Dexter, D. Tsikritsis, P. Zarmpi, R. H. Guy (2024) Visualization of topical drug delivery with label-free chemical imaging
P. Zarmpi, D. Tsikritsis, J-L. Vorng, N. A. Belsey, A. L. Bunge, T. J. Woodman, M. B. Delgado-Charro, R. H. Guy (2024) Evaluation of chemical disposition in skin by stimulated Raman scattering microscopy
E. J. Legge, M. Stewart, L. P. Contreras Chávez, H. Zhang, D. Tsikritsis, N. A. Belsey, M. McAllister, J. R. Murphy, K. Mingard, C. Minelli (2024) Advanced Chemical and Imaging Methods for Studying Structure Morphology and Excipients Solid State Transformations in Pharmaceutical Multiparticulate Formulations
A. Goel, R. Pendlington, S. Glavin, T. Chen, N. A. Belsey (2024) Characterisation of skin penetration pathways using stimulated Raman scattering microscopy
E. J. Legge, R. T. Coones, W. A. Lee, Y. Pei, N. A. Belsey, C. Minelli (2025) Non-invasive quantitative chemical measurements of liposomal formulations using Raman spectroscopy
C. Dondi, D. Tsikritsis, J-L. Vorng, G. Greenidge, I. E. Kepiro, N. A. Belsey, G. McMahon, I. S. Gilmore, M. G. Ryadnov, M. Shaw (2025) Multiparametric physicochemical analysis of a type 1 collagen 3D cell culture model using light and electron microscopy and mass spectrometry imaging
N. A. Belsey, D. Tsikritsis, C. Dondi, J-L. Vorng, A. Dexter, M. Shaw (2025) Combining vibrational and fluorescence microscopies with mass spectrometry imaging for visualization of drug delivery