Yuxiu Chen

Dr Yuxiu (Phil) Chen

My publications


Yuxiu Chen, Simone Krings, Joshua R. Booth, Stefan A.F Bon, Suzie Hingley-Wilson, Joseph Keddie (2020)Introducing Porosity in Colloidal Biocoatings to Increase Bacterial Viability, In: Biomacromolecules American Chemical Society

A biocoating confines non-growing, metabolically-active bacteria within a synthetic colloidal polymer (i.e. latex) film. Bacteria encapsulated inside biocoatings can perform useful functions, such as a biocatalyst in wastewater treatment. A biocoating needs to have high a permeability to allow a high rate of mass transfer for rehydration and the transport of both nutrients and metabolic products. It therefore requires an interconnected porous structure. Tuning the porosity architecture is a challenge. Here, we exploited rigid tubular nanoclays (halloysite) and non-toxic latex particles (with a relatively high glass transition temperature) as the colloidal “building blocks” to tailor the porosity inside biocoatings containing Escherichia coli bacteria as a model organism. Electron microscope images revealed inefficient packing of the rigid nanotubes and proved the existence of nanovoids along the halloysite/polymer interfaces. Single-cell observations using confocal laser scanning microscopy provided evidence for metabolic activity of the E. coli within the biocoatings through the expression of yellow fluorescent protein. A custom-built apparatus was used to measure the permeability of a fluorescein sodium salt in the biocoatings. Whereas there was no measurable permeability in a coating made from only latex particles, the permeability coefficient of the composite biocoatings increased with increasing halloysite content up to a value of 110-4 m h-1. The effects of this increase in permeability was demonstrated through a specially-developed resazurin reduction assay. Bacteria encapsulated in halloysite composite biocoatings had statistically significant higher metabolic activities in comparison to bacteria encapsulated in a non-optimized coating made from latex particles alone.

JS Sharpe, YL Chen, RM Gwilliam, AK Kewell, S Ledain, CN McKinty, MA Lourenco, T Butler, KP Homewood, KJR Kirkby, G Shao (2000)Structural characterisation of ion beam synthesised Ru2Si3, In: NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION B-BEAM INTERACTIONS WITH MATERIALS AND ATOMS161pp. 937-940
JS Sharpe, YL Chen, RM Gwilliam, AK Kewell, CN McKinty, MA Lourenco, G Shao, KP Homewood, KR Kirkby (1999)Ion beam synthesized Ru2Si3, In: APPLIED PHYSICS LETTERS75(9)pp. 1282-1283 AMER INST PHYSICS
BB Skorodumov, GV Rogachev, P Boutachkov, A Aprahamian, VZ Goldberg, A Mukhamedzhanov, S Almaraz, H Amro, FD Becchetti, S Brown, Y Chen, H Jiang, JJ Kolata, LO Lamm, M Quinn, A Woehr (2007)Lowest excited states of O-13, In: PHYSICAL REVIEW C75(2)ARTN 0pp. ?-? AMERICAN PHYSICAL SOC
H Aihara, CA Prieto, D An, SF Anderson, E Aubourg, E Balbinot, TC Beers, AA Berlind, SJ Bickerton, D Bizyaev, M Blanton, JJ Bochanski, AS Bolton, J Bovy, WN Brandt, J Brinkmann, P Brown, JR Brownstein, NG Busca, H Campbell, MA Carr, Y Chen, C Chiappini, J Comparat, N Connolly, M Cortes, RAC Croft, A Cuesta, LN Da Costa, JRA Davenport, K Dawson, S Dhital, A Ealet, G Ebelke, EM Edmondson, DJ Eisenstein, S Escoffier, M Esposito, ML Evans, X Fan, BF Castellá, A Font-Ribera, P Frinchaboy, J Ge, BA Gillespie, G Gilmore, JIG Hernández, JR Gott, A Gould, EK Grebel, JE Gunn, JC Hamilton, P Harding, DW Harris, SL Hawley, FR Hearty, S Ho, DW Hogg, JA Holtzman, K Honscheid, N Inada, II Ivans, L Jiang, JA Johnson, C Jordan, W Jordan, EA Kazin, D Kirkby, MA Klaene, GR Knapp, JP Kneib, CS Kochanek, L Koesterke, JA Kollmeier, RG Kron, H Lampeitl, D Lang, JM Le Goff, YS Lee, YT Lin, DC Long, CP Loomis, S Lucatello, B Lundgren, RH Lupton, Z Ma (2011)Erratum: The eighth data release of the sloan digital sky survey: First data from SDSS-III (The Astrophysical Journal Supplement Series (2011) 193 (29)), In: Astrophysical Journal, Supplement Series195(2)
JR Varcoe, RCT Slade, GL Wright, Y Chen (2006)Steady-state dc and impedance investigations of H-2/O-2 alkaline membrane fuel cells with commercial Pt/C, Ag/C, and Au/C cathodes, In: JOURNAL OF PHYSICAL CHEMISTRY B110(42)pp. 21041-21049 AMER CHEMICAL SOC