University of Surrey
- Appointed Reader (Clinical) 2019
- Clinical Senior Lecturer 2016
Royal Surrey County Hospital
- Consultant intensivist 2012.
- Chairman of SPACeR group.
Royal Brompton Hospital / Natonal Heart and Lung Institute, Imperial College
- Out of programme research, culmination in the award of a PhD in 2011.
Clinical trainee in respiratory, intensive care and general medicine, London 2005-2012
Graduated University of Southampton, Bachelor of Medicine 1999
Areas of specialism
Critical care medicine;
Ben Creagh-Brown’s main research interests are the prevention of complications of surgery (pulmonary, cardiovascular, gastrointestinal, neurological and muscular), and the complications of sepsis, particularly pneumonia.
Methodologies: observational studies, interventional trials, ‘big data’ analyses, healthy volunteer studies.
Postgraduate research supervision
Current higher degree students (2019):
- MD Dr Elizabeth Potter, Anaesthesia & Intensive Care Medicine
- PhD Dr Gabor Dudas, Anaesthesia & Intensive Care Medicine
- PhD Miss Ismita Chhetri, Physiology
- MD Dr Katerina Papadopoulou, Anaesthesia
- MD Mr Paul MacKenzie, GI Surgery
Design: A retrospective cohort study of all patients who had gastrointestinal surgery and were admitted directly to the ICU between 2008 and 2012.
Setting: Two hundred forty-nine hospitals in the United Kingdom.
Patients: One hundred twenty-one thousand nine hundred ninety patients.
Measurements and Main Results: Peak blood lactate in the first 24 hours of admission to critical care, acute hospital mortality, length of stay, and other variables routinely collected within the U.K. Intensive Care National Audit and Research Centre Case Mix Programme database. Elevated blood lactate was associated with increased risk of death and prolonged duration of stay, and the relationship was maintained once adjusted for confounding variables. The positive association between mortality and levels of blood lactate continued down into the ?normal range,? without evidence of a plateau. There was no difference in the extent to which hyperlactatemia was related to mortality between patients admitted following elective and emergency surgery.
Conclusions: These findings have implications for our understanding of the role of lactate in critically ill patients.