Daniel Sebastia Saez

Dr Daniel Sebastia Saez

Associate Tutor & Research Fellow in Chemical Engineering
+44 (0)1483 686568
33 BC 02

Academic and research departments

Department of Chemical and Process Engineering.



Research interests



List of Publications

Book Chapters

  1. D. Sebastia-Saez et al. Advancing CCSU technologies with Computational Fluid Dynamics (CFD): A look at the future by linking CFD and Process Simulations. In: T. Reina, J. Odriozola, H. Arellano-Garcia (Eds.): Engineering Solutions for CO2 Conversion. Wiley, Weinheim, Germany. ISBN-13: 978-3527346394. 2021.https://www.wiley.com/en-am/Engineering+Solutions+for+CO2+Conversion-p-9783527346394

Journal Articles Under Review

  1. D. Sebastia-Saez, et al. In-silico modelling and analysis of transdermal permeation of large molecules assisted by hypobaric pressure. Pharmaceutical Research.
  2. D. Sebastia-Saez, Panayiotis Kattou, et al. In silico study of the lipophilicity of the follicular route during topical drug delivery. Link to arXiv: https://arxiv.org/abs/2012.02728

Published Journal Articles

  1. F. Benaouda, …, D. Sebastia-Saez, et al. Needleless administration of advanced therapies into the skin via the appendages using a hypobaric patch. PNAS 119(18):e2120340119, 2022. https://doi.org/10.1073/pnas.2120340119
  2. I. Nascu, D. Sebastia-Saez, et al. Global sensitivity analysis for a perfusion bioreactor based on CFD modelling. Computers and Chemical Engineering 163:107829, 2022. https://doi.org/10.1016/j.compchemeng.2022.107829

  3. D. Sebastia-Saez, Faiza Benaouda, Charlie Lim, et al. Numerical analysis of the strain distribution in skin domes formed upon the application of hypobaric pressure. Skin Research and Technology 00:1–11, 2021. http://doi.org/10.1111/srt.13047
  4. Francisco M. Baena-Moreno, D. Sebastia-Saez, et al. Analysis of the potential for biogas upgrading to syngas via catalytic reforming in the United Kingdom. Renewable and Sustainable Energy Research 144:110939. 2021. https://doi.org/10.1016/j.rser.2021.110939
  5. Jun Liang, …, D. Sebastia-Saez, et al. Optimal separation of acetonitrile and pyridine from industrial wastewater. Chemical Engineering Research & Design 169:54–65, 2021. https://doi.org/10.1016/j.cherd.2021.03.009
  6. D. Sebastia-Saez, A. Burbidge, J. Engmann, M. Ramaioli. New trends in mechanistic transdermal drug delivery modelling: Towards an accurate geometric description of the skin microstructure. Computers and Chemical Engineering 141:106976, 2020. https://doi.org/10.1016/j.compchemeng.2020.106976
  7. F.M. Baena-Moreno, D. Sebastia-Saez, et al. Is the production of biofuels and bio-chemicals always profitable? Co-production of biomethane and urea from biogas as case study. Energy Conversion and Management 220:113058, 2020. https://doi.org/10.1016/j.enconman.2020.113058
  8. A. Anagnostopoulos, D. Sebastia-Saez, et al. Finite element modelling of the thermal performance of salinity gradient solar ponds. Energy 203:117861, 2020. https://doi.org/10.1016/j.energy.2020.117861
  9. E. Stephenson..., D. Sebastia-Saez, et al. Numerical modelling of the interaction between eccrine sweat and textile fabric for the development of smart clothing. International Journal of Clothing Science and Technology. Article in Press. 2020. https://doi.org/10.1108/IJCST-07-2019-0100
  10. D. Sebastia-Saez, T.R. Reina, R. Silva, H. Arellano-Garcia. Synthesis and characterisation of n-octacosane@silica nanocapsules for thermal storage applications. International Journal of Energy Research 44(3):2306–2315, 2020. https://doi.org/10.1002/er.5039
  11. H. Arellano-Garcia..., D. Sebastia-Saez. Hydrogen Production via Load-Matched Coupled Solar-Proton Exchange Membrane Electrolysis Using Aqueous Methanol. Chemical Engineering and Technology 42(11):2340-2347, 2019https://doi.org/10.1002/ceat.201900285
  12. F.M. Baena-Moreno..., D. Sebastia-Saez et al. Physicochemical comparison of precipitated calcium carbonate for different configurations of a biogas upgrading unit. Journal of Chemical Technology and Biotechnology 94(7):2256–2262, 2019https://doi.org/10.1002/jctb.6013
  13. D. Sebastia-Saez et al. Numerical and experimental characterization of the hydrodynamics and drying kinetics of a barbotine slurry spray. Chemical Engineering Science 195:83–94, 2019. https://doi.org/10.1016/j.ces.2018.11.040
  14. D. Sebastia-Saez et al. Effect of the contact angle on the morphology, residence time distribution and mass transfer into liquid rivulets: A CFD study. Chemical Engineering Science 176:356– 366, 2018. https://doi.org/10.1016/j.ces.2017.09.046
  15. D. Sebastia-Saez et al. On the effect of the liquid phase Froude number on the interface area of gravity-driven liquid films in structured packing. Chemical Engineering Research and Design 130:208–218, 2018. https://doi.org/10.1016/j.cherd.2017.12.003
  16. S. Hoeser, ..., D. Sebastia-Saez et al. Adaption of control structure design methods to an industrial plant engineering workflow. Industrial and Engineering Chemistry Research 56(48):14270–14281, 2017. https://doi.org/10.1021/acs.iecr.7b02582
  17. D. Sebastia-Saez et al. Numerical modelling of braiding and meandering instabilities in gravity-driven liquid rivulets. Chemie Ingenieur Technik 89(11):1515–1522, 2017https://doi.org/10.1002/cite.201700034
  18. D. Sebastia-Saez, et al. Meso-scale CFD study of the pressure drop, liquid hold-up, interfacial area and mass transfer in structured packing materials. International Journal of Greenhouse Gas Control 42:388–399, 2015. https://doi.org/10.1016/j.ijggc.2015.08.016
  19. D. Sebastia-Saez, et al. Micro-scale CFD modeling of reactive mass transfer in falling liquid films within structured packing materials. International Journal of Greenhouse Gas Control 33:40–50, 2015. https://doi.org/10.1016/j.ijggc.2014.11.019
  20. D. Sebastia-Saez, et al. Micro-scale CFD study about the influence of operative parameters on physical mass transfer within structured packing elements. International Journal of Greenhouse Gas Control 28:180–188, 2014. https://doi.org/10.1016/j.ijggc.2014.06.029
  21. D. Sebastia-Saez, et al. 3D modeling of hydrodynamics and physical mass transfer characteristics of liquid film flows in structured packing elements. International Journal of Greenhouse Gas Control 19:492–502, 2013. https://doi.org/10.1016/j.ijggc.2013.10.013

Peer-Reviewed Conference Articles

  1. M. Hamdan, D. Sebastia-Saez, M. Hamdan, H. Arellano-Garcia. CFD analysis of the use of desert sand as thermal energy storage medium in a solar powered fluidised bed harvesting unit. Computer Aided Chemical Engineering. To appear. https://doi.org/10.1016/B978-0-12-823377-1.50059-8
  2. A. Al Hmoud, D. Sebastia-Saez, et al. Comparative numerical analysis of different materials in photovoltaic thermal solar hybrid panels. Computer Aided Chemical Engineering 46:793–798, 2019. https://doi.org/10.1016/B978-0-12-818634-3.50133-8
  3. D. Sebastia-Saez et al. CFD modelling of the evaporation of biphasic (solid- liquid) individual droplets in a spray dryer. Chemical Engineering Transactions 74:421–426, 2019. DOI: 10.3303/CET1974071
  4. N. Foster, D. Sebastia-Saez, et al. Fractal branch-like shell and tube heat exchanger: A CFD study of the shell side performance. IFAC-PapersOnLine 52–1:100–105, 2019. https://doi.org/10.1016/j.ifacol.2019.06.044
  5. S. Hajizeinalibioki, D. Sebastia-Saez, et al. Dull or bright you still get electric delight: A new approach to the design of all-weather panels. Computer Aided Chemical Engineering 43:211–216, 2018. https://doi.org/10.1016/B978-0-444-64235-6.50038-3
  6. D. Sebastia-Saez, et al. A model-based approach to design miniaturised structured packings for highly efficient mass transfer in gas/liquid multiphase flows. Computer Aided Chemical Engineering 821–826, 2018. https://doi.org/10.1016/B978-0-444-64235-6.50144-3
  7. D. Sebastia-Saez, et al. CFD modelling of structured packings at small- and meso-scale. Energy Procedia 114:1601–1614, 2017.https://doi.org/10.1016/j.egypro.2017.03.1290 
  8. D. Sebastia-Saez, et al. Volume of fluid modeling of the reactive mass transfer of CO2 into aqueous amine solutions in structured packed elements at microscale. Energy Procedia 63:1229–1242, 2017. https://doi.org/10.1016/j.egypro.2014.11.133  

List of National and International Invited and Contributed Talks

  • 2020 3DbioNet Meeting 14–15 September, On-line. The effect of the application of hypobaric pressure on transdermal drug delivery – A numerical analysis. 
  • 2020 Joint IBIN/3DbioNet Meeting 20–21 January, London (United Kingdom). Numerical study of enhanced topical drug delivery through mechanically stretched hair follicles.
  • 2019 ICheap14. 14th International Congress of Chemical and Process Engineering. 26–29 May, Bologna (Italy). CFD modelling of the evaporation of biphasic (solid-liquid) individual droplets in a spray dryer.
  • 2018 Invited Talk. Technische Universität Berlin. 1 February, Berlin (Germany). CFD modelling of the multiphase flow in structured packings.
  • 2017 AEM 2017. 1st International Conference on Solar Energy Materials. 13 September, Guildford (United Kingdom). A novel power unit concept using CSP and desert sand.
  • 2017 Process Systems Engineering Research Day. 27 June. London, United Kingdom. A novel power unit concept using CSP and desert sand.
  • 2017 ChemEngDayUK 2017. 27–28 March. Birmingham, United Kingdom. CFD study of the gas-liquid interface in structured packings.
  • 2015 UKCCSRC Autumn Biannual Meeting 2015, CCS in the UK - Taking Stock. 8–9 September. Glasgow, United Kingdom