
Dr Daniel Sebastia-Saez
About
Biography
A passionate computational scientist with 10+ years' experience in the development of mathematical models for a range of applications in Bioengineering and Energy Engineering.
An effective communicator with 20+ scientific publications in top tier journals and 10+ contributions to international conferences.
ResearchResearch interests
My research has been carried out in the frame of the following projects:
- From 10.2019-To date. Engineering a topical hypobaric patch: A needle free solution for biopharmaceutical drug administration into the skin. EPSRC (United Kingdom). King’s College London & University of Surrey. Project No. EP/S021159/1. https://gow.epsrc.ukri.org/NGBOViewGrant.aspx?GrantRef=EP/S021167/1#:~:text=The%20device%20uses%20a%20small,blood%20flow%20underneath%20the%20chamber.
- 02.2018–09.2019. Stepping towards the industrial 6th sense. EPSRC (United Kingdom). University of Surrey. Project No. EP/R001588/1. https://gow.epsrc.ukri.org/NGBOViewGrant.aspx?GrantRef=EP/R001588/1
- 10.2017–01.2018. Industrial Funding from Nestle Research Center (Switzerland). Computational modelling of transdermal drug delivery.
- 01.2013–09.2017. Computational Modelling and optimisation of carbon capture reactors. EPSRC (United Kingdom). Project No. EP/J020184/1 (Cranfield University) and EP/J020184/2 (University of Surrey) https://gow.epsrc.ukri.org/NGBOViewGrant.aspx?GrantRef=EP/J020184/2
Research interests
My research has been carried out in the frame of the following projects:
- From 10.2019-To date. Engineering a topical hypobaric patch: A needle free solution for biopharmaceutical drug administration into the skin. EPSRC (United Kingdom). King’s College London & University of Surrey. Project No. EP/S021159/1. https://gow.epsrc.ukri.org/NGBOViewGrant.aspx?GrantRef=EP/S021167/1#:~:text=The%20device%20uses%20a%20small,blood%20flow%20underneath%20the%20chamber.
- 02.2018–09.2019. Stepping towards the industrial 6th sense. EPSRC (United Kingdom). University of Surrey. Project No. EP/R001588/1. https://gow.epsrc.ukri.org/NGBOViewGrant.aspx?GrantRef=EP/R001588/1
- 10.2017–01.2018. Industrial Funding from Nestle Research Center (Switzerland). Computational modelling of transdermal drug delivery.
- 01.2013–09.2017. Computational Modelling and optimisation of carbon capture reactors. EPSRC (United Kingdom). Project No. EP/J020184/1 (Cranfield University) and EP/J020184/2 (University of Surrey) https://gow.epsrc.ukri.org/NGBOViewGrant.aspx?GrantRef=EP/J020184/2
Teaching
ENGM255 Advanced Process Control
ENG2094 Control
Publications
List of Publications
Journal Articles Under Review
1. D. Sebastia-Saez, Panayiotis Kattou, et al. In silico study of the lipophilicity of the follicular route during topical drug delivery. Link to arXiv: https://arxiv.org/abs/2012.02728
Published Journal Articles
1. D. Sebastia-Saez, et al. In-silico modelling and analysis of transdermal permeation of large molecules assisted by hypobaric pressure. Pharmaceutical Research. 2022. https://doi.org/10.1007/s11095-022-03423-7
2. F. Benaouda, …, D. Sebastia-Saez, et al. Needleless administration of advanced therapies into the skin via the appendages using a hypobaric patch PNAS 119(18):e2120340119, 2022. https://doi.org/10.1073/pnas.2120340119
3. I. Nascu, D. Sebastia-Saez, et al. Global sensitivity analysis for a perfusion bioreactor based on CFD modelling. Computers and Chemical Engineering 163:107829, 2022. https://doi.org/10.1016/j.compchemeng.2022.107829
4. J. Gonzalez-Arias, ..., D. Sebastia-Saez, et al. Biogas upgrading to biomethane as a local source of renewable energy to power light marine transport: Profitability analysis for the county of Cornwall. Waste Management 137:81–88, 2022. https://doi.org/10.1016/j.wasman.2021.10.037
5. D. Sebastia-Saez, Faiza Benaouda, Charlie Lim, et al. Numerical analysis of the strain distribution in skin domes formed upon the application of hypobaric pressure. Skin Research and Technology 00:1–11, 2021. http://doi.org/10.1111/srt.13047
6. Francisco M. Baena-Moreno, D. Sebastia-Saez, et al. Analysis of the potential for biogas upgrading to syngas via catalytic reforming in the United Kingdom. Renewable and Sustainable Energy Research 144:110939. 2021. https://doi.org/10.1016/j.rser.2021.110939
7. Jun Liang, …, D. Sebastia-Saez, et al. Optimal separation of acetonitrile and pyridine from industrial wastewater. Chemical Engineering Research & Design 169:54–65, 2021. https://doi.org/10.1016/j.cherd.2021.03.009
8. D. Sebastia-Saez, A. Burbidge, J. Engmann, M. Ramaioli. New trends in mechanistic transdermal drug delivery modelling: Towards an accurate geometric description of the skin microstructure. Computers and Chemical Engineering 141:106976, 2020. https://doi.org/10.1016/j.compchemeng.2020.106976
9. F.M. Baena-Moreno, D. Sebastia-Saez, et al. Is the production of biofuels and bio-chemicals always profitable? Co-production of biomethane and urea from biogas as case study. Energy Conversion and Management 220:113058, 2020. https://doi.org/10.1016/j.enconman.2020.113058
10. A. Anagnostopoulos, D. Sebastia-Saez, et al. Finite element modelling of the thermal performance of salinity gradient solar ponds. Energy 203:117861, 2020. https://doi.org/10.1016/j.energy.2020.117861
11. E. Stephenson..., D. Sebastia-Saez, et al. Numerical modelling of the interaction between eccrine sweat and textile fabric for the development of smart clothing. International Journal of Clothing Science and Technology. Article in Press. 2020. https://doi.org/10.1108/IJCST-07-2019-0100
12. D. Sebastia-Saez, T.R. Reina, R. Silva, H. Arellano-Garcia. Synthesis and characterisation of n-octacosane@silica nanocapsules for thermal storage applications. International Journal of Energy Research 44(3):2306–2315, 2020. https://doi.org/10.1002/er.5039
13. H. Arellano-Garcia..., D. Sebastia-Saez. Hydrogen Production via Load-Matched Coupled Solar-Proton Exchange Membrane Electrolysis Using Aqueous Methanol. Chemical Engineering and Technology 42(11):2340-2347, 2019. https://doi.org/10.1002/ceat.201900285
14. F.M. Baena-Moreno..., D. Sebastia-Saez et al. Physicochemical comparison of precipitated calcium carbonate for different configurations of a biogas upgrading unit. Journal of Chemical Technology and Biotechnology 94(7):2256–2262, 2019. https://doi.org/10.1002/jctb.6013
15. D. Sebastia-Saez et al. Numerical and experimental characterization of the hydrodynamics and drying kinetics of a barbotine slurry spray. Chemical Engineering Science 195:83–94, 2019. https://doi.org/10.1016/j.ces.2018.11.040
16. D. Sebastia-Saez et al. Effect of the contact angle on the morphology, residence time distribution and mass transfer into liquid rivulets: A CFD study. Chemical Engineering Science 176:356– 366, 2018. https://doi.org/10.1016/j.ces.2017.09.046
17. D. Sebastia-Saez et al. On the effect of the liquid phase Froude number on the interface area of gravity-driven liquid films in structured packing. Chemical Engineering Research and Design 130:208–218, 2018. https://doi.org/10.1016/j.cherd.2017.12.003
18. S. Hoeser, ..., D. Sebastia-Saez et al. Adaption of control structure design methods to an industrial plant engineering workflow. Industrial and Engineering Chemistry Research 56(48):14270–14281, 2017. https://doi.org/10.1021/acs.iecr.7b02582
19. D. Sebastia-Saez et al. Numerical modelling of braiding and meandering instabilities in gravity-driven liquid rivulets. Chemie Ingenieur Technik 89(11):1515–1522, 2017. https://doi.org/10.1002/cite.201700034
20. D. Sebastia-Saez, et al. Meso-scale CFD study of the pressure drop, liquid hold-up, interfacial area and mass transfer in structured packing materials. International Journal of Greenhouse Gas Control 42:388–399, 2015. https://doi.org/10.1016/j.ijggc.2015.08.016
21. D. Sebastia-Saez, et al. Micro-scale CFD modeling of reactive mass transfer in falling liquid films within structured packing materials. International Journal of Greenhouse Gas Control 33:40–50, 2015. https://doi.org/10.1016/j.ijggc.2014.11.019
22. D. Sebastia-Saez, et al. Micro-scale CFD study about the influence of operative parameters on physical mass transfer within structured packing elements. International Journal of Greenhouse Gas Control 28:180–188, 2014. https://doi.org/10.1016/j.ijggc.2014.06.029
23. D. Sebastia-Saez, et al. 3D modeling of hydrodynamics and physical mass transfer characteristics of liquid film flows in structured packing elements. International Journal of Greenhouse Gas Control 19:492–502, 2013. https://doi.org/10.1016/j.ijggc.2013.10.013