Dr Debruin is an Early Career Researcher specialised in muscle physiology and pre-clinical trials. Dr Debruin completed her PhD at Victoria University, (Melbourne, Australia) under the supervision of Prof Hayes, where she won the prestigious University Medal for Academic Excellence in Research. Dr Debruin’s PhD explored how vitamin D in combination with other treatments, improves skeletal muscle and cardiac function in health and disease, an area of increasing clinical significance. Dr Debruin’s expertise in muscle function testing under in vivo, in situ and ex vivo conditions are highly sought after, with multiple collaborations established with various research groups and industry partners. She has exceptional expertise in developing, and working with, animal models of muscle atrophy and employing a variety of techniques. Dr Debruin has years of experience working with industry as a co-investigator on multiple projects centred around Duchenne Muscular Dystrophy and other muscle wasting conditions. She is an active member at the Australian Institute for Musculoskeletal Science (AIMSS) in the Geroscience and Regenerative Medicine programs and is an Anjunct Fellow at the Institue of Health and Sport at Victoria University.
Danielle's previous Post-Doctoral Fellowship role at the University of Melbourne (Australia) primarily focused on understanding the complex nature of the extracellular matrix (ECM), and its components, in various muscle diseases. The work undertaken has lead to her current post in the Department of Biochemical and Physiological Sciences Faculty at the University of Surrey under the supervision of Dr Salvatore Santamaria.
- Zanker, J., Scott, D., Alajlouni, D., Kirk, B., Bird, S., Debruin, D.A., Vogrin, S., Bliuc, D., Tran, T., Cawthon, P., Duque, G., & Center, J. R. (2023). Mortality, falls and slow walking speed are predicted by different muscle strength and physical performance measures in women and men. Archives of gerontology and geriatrics, 114, 105084
- Arman B. M., Binder N. K., de Alwis N., Beard S., Debruin D. A., Hayes A., Tong S., Kaitu’u-Lino T.J. & Hannan N. J. (2023). Assessment of the tocolytic nifedipine in preclinical primary models of preterm birth. Sci Rep 13, 5646
- Saedi A., Debruin D. A. Hayes, A. & Hamrick M. (2022). Lipid metabolism in sarcopenia. Bone.
- Sligar, J., Debruin, D. A., Saner, N. J., Philp, A. M., & Philp, A. (2022). The importance of mitochondrial quality control for maintaining skeletal muscle function across health span. American journal of physiology; Cell physiology, 322(3), C461–C467.
- Campelj, D.G., Debruin, D.A., Timpani, C.A. et al. Sodium nitrate co-supplementation does not exacerbate low dose metronomic doxorubicin-induced cachexia in healthy mice. (2020) Sci Rep 10, 15044 .
- Debruin D.A., Timpani, C.A., Rybalka, E., Goodman, C.G., Hayes, A. (2020) Exercise may ameliorate the detrimental effects of high vitamin D supplementation on muscle function in mice. Journal of Bone and Mineral Research.
- Kirk B, Phu S, Debruin D.A., Hayes A, Duque G. Aging Muscle and Sarcopenia. In: Rattan SIS, editor. Encyclopedia of Biomedical Gerontology. Oxford: Academic Press; 2020. p. 120-31
- Hayes A., Rybalka E., Debruin D.A., Hanson E.D., Scott D. & Sanders K. (2019) The Effect of Yearly-Dose Vitamin D Supplementation on Muscle Function in Mice. Nutrients. May 17;11(5). pii: E1097.
- Rybalka, E.; Timpani, C.A.; Debruin, D.A.; Bagaric, R.M.; Campelj, D.G.; Hayes, A. (2020) The Failed Clinical Story of Myostatin Inhibitors against Duchenne Muscular Dystrophy: Exploring the Biology behind the Battle. Cells. 9, 2657.
- Debruin D.A., Andreacchio N., Hanson E.D., Timpani C.A., Rybalka E. & Hayes A. (2019) The Effect of Vitamin D Supplementation on Skeletal Muscle in the mdx Mouse Model of Duchenne Muscular Dystrophy. Sports (Basel). Apr 26;7(5). pii: E96.