Dr Federica Orsenigo
Academic and research departments
Faculty of Health and Medical Sciences, Department of Biochemical Sciences, School of Biosciences, Section of Immunology.About
Biography
I obtained a BSc in Biotechnologies in 2017 and a MSc in Industrial Biotechnologies in 2019 at University of Milano-Bicocca (Milan, Italy), joining a Molecular and Cellular Immunology lab for a 1-year internship during my MSc. My focus during my MSc internship was understanding calcium fluxes in innate immune cells and their impact on inflammatory processes and in pathologies such as rheumatoid arthritis.
I then obtained my dual PhD in Molecular and Translational Medicine at University of Milano-Bicocca (Milan, Italy) and in Immunology at University of Surrey, both awarded in 2023. During my PhD, I focused on human innate immune cells in the context of infections (SARS-CoV-2 and sepsis), in response to vaccine administration and in cancer (specifically non-small cell lung cancer and colorectal cancer). I specialised in in vitro models, flow cytometry, cell sorting, western blotting, single-cell RNA sequencing and tissue imaging.
I then joined Prof. Clare Mills’ lab at University of Surrey in 2023 as Research Fellow in Food and Molecular Immunology.
ResearchResearch interests
I joined Prof. Clare Mills’ lab as Research Fellow A in February 2023 on a project funded by the European Food Safety Authority (EFSA) (https://www.efsa.europa.eu/en) and focused on assessing in silico tools for allergenicity prediction in the context of food allergies.
For my new project, part of the Giant Leaps EU project (https://giantleaps.eu/), my research interest is to develop new approaches for allergenicity risk assessment of innovative/novel proteins. This is being realised through developing in vitro methods, including the use of human immune cell models, for assessing allergenic potential of alternative proteins, and through linking the readouts of the cell models with clinical phenotypes and HLA genotypes of food allergic patients.
Research interests
I joined Prof. Clare Mills’ lab as Research Fellow A in February 2023 on a project funded by the European Food Safety Authority (EFSA) (https://www.efsa.europa.eu/en) and focused on assessing in silico tools for allergenicity prediction in the context of food allergies.
For my new project, part of the Giant Leaps EU project (https://giantleaps.eu/), my research interest is to develop new approaches for allergenicity risk assessment of innovative/novel proteins. This is being realised through developing in vitro methods, including the use of human immune cell models, for assessing allergenic potential of alternative proteins, and through linking the readouts of the cell models with clinical phenotypes and HLA genotypes of food allergic patients.