I am Professor of Medical Radiation Imaging in The Centre for Vision Speech and Signal Processing (CVSSP). I joined the university in 2012 with a track record of 25 years in the field of medical radiation imaging and radiotherapy technology. Joining a world leading centre in CVSSP, and a university with such a great portfolio of science and engineering activity as Surrey, was a great opportunity to contribute to the development of the next generation of medical technology.
I have a first degree from The University of Aston and a DPhil from The University of Oxford. I have published over 150 papers in primary journals and over 500 papers in total. I have won grant funding from: Cancer Research UK, The Wellcome Trust, The National Institute for Healthcare Research, The Medical Research Council, EPSRC and STFC.
I am mamber of the Trial Management Group for the IMPORT LOW and IMPORT HIGH Breast Radiotherapy Trials. For more information see: http://www.cancerresearchuk.org/about-cancer/find-a-clinical-trial/a-trial-comparing-different-ways-of-giving-radiotherapy-for-low-risk-early-stage-breast-cancer http://www.cancerresearchuk.org/about-cancer/find-a-clinical-trial/a-trial-comparing-different-ways-of-giving-radiotherapy-for-early-stage-breast-cancer My main interest in these trials has been in medical imaging. This work has led to a NIHR/MRC funded project, IMPORT-IGRT and national recommendations for imaging to verify the accuracy of radiotherapy for breast cancer: https://www.journalslibrary.nihr.ac.uk/programmes/eme/0915016/#/
I am a member of The National Cancer Research Institute CTRad (Clinical and Translational Radiotherapy Research Working Group) since 2015 I have been joint chair of Workstream 4 and an Executive Board Member. For more information see: http://ctrad.ncri.org.uk/
In January 2018 I took on the role of CVSSP and NPL (National Physical Laboratory) Professor of Medical Imaging. The purpose of this activity is to develop the relationship between Surrey University and NPL in medical related research and other activities.
Contact the press team
Phone: +44 (0)1483 684380 / 688914 / 684378
Out-of-hours: +44 (0)7773 479911
Senate House, University of Surrey
Guildford, Surrey GU2 7XH
My main research interests involve the application of physics and engineering to medical imaging problems, particularly in radiotherapy. Below are listed some of my current projects:
With researchers at The Royal Surrey Hospital, Alliance Medical Limited and The National Physical Laboratory we are developing quantitative radiomics methods with application to cancer. The main application is to lung cancer where we have developed some promising biomarkers and have evaluated the robustness of some common raidomics markers. In this context there is strong evidence that some features in medical images are a good indication of the likely outcome of the treatment. Such features include metabolism and measures of texture. We are investigating how this may be used to improve patient treatments and predict outcome. We are also investigating how methods of analysis of “big data” might be used to provide greater power in understanding the relationship between imaging and other patient measurements and the success of the treatment.
A major project has evaluated the use of imaging during treatment to improve accuracy of breast radiotherapy. This was carried out as part of a national trial called IMPORT HIGH: http://www.cancerresearchuk.org/about-cancer/trials/a-trial-comparing-different-ways-of-giving-radiotherapy-for-early-stage-breast-cancer. The results of the study are shortly to be published by The National Institute of Healthcare Research and show a clear benefit from using “image guidance” in terms of reduced dose to non-target tissues: http://www.nets.nihr.ac.uk/projects/eme/0915016.
With Elekta Limited and the National Physical Laboratory we are developing methods to allow standardisation of imaging and treatment in MRI guided radiotherapy to support the exciting new concept of the MR Linac dveloped by Elekta.
Ultrasound is a very important imaging method in cancer. It is often used in in conjunction with CT in a treatment called brachytherapy, in which radioactive sources are placed inside the body. Our collaborators at the Royal Surrey are leaders in this treatment method. We are investigating how new approaches to ultrasound, tracking methods and image processing may be used to help develop highly accurate treatments in image guided brachytherapy.
Proton beam radiotherapy is an advanced form of cancer treatment that is seeing great investment in the UK. A major challenge with proton radiotherapy is imaging the patient to ensure the treatment is delivered accurately. Ideally this would be carried out using the proton beam, but this presents several major challenges. The CVSSP medical imaging group were originating members of the Pravda consortium which has developing new imaging methods to obtain 3D images of the patient using the proton beam. This work combining novel detectors and methods of “reconstructing” an image of the patient. Surrey's contribution is in developing the image reconstruction: We presented our work at the 2014 Royal Society Summer Science Exhibition: http://sse.royalsociety.org/2014. This work continues with collaborations within the university and with proton radiotherapy providers.
The National Physical Laboratory
The Royal Surrey Hospital NHS Foundation Trust
The Royal Marsden Hospital NHS Foundation Trust and The Institute of Cancer Research
Ashford and St Peter's Hospitals NHS Foundation Trust
University Hospitals Birmingham NHS Foundation Trust
The University of Birmingham
Alliance Medical Limited
BEng/MEng - Electronics 1: Electronic Circuits
BEng/MEng - Electronics 2: Analogue and Digital Electronics
MSc - Therapy Physics
Postgraduate research supervision
Aaron Axford is researching for a PhD in "Standardisation of Magnetic Resonance Imaging in Radiotherapy". This project is in partnership with Elekta Limited and The National Physical Laboratory
Helen Wang is researching for a PhD in "Texture Analysis in Radiotherapy". This project is in partnership with Alliance Medical Limited, The Royal Surrey Hospital and The National Physical Laboratory
George Papachristodoulou is researching for a PhD in "New Imaging Techniques for Brachytherapy". This project is in partnership with The Royal Surrey Hospital
Dr Sheaka Alobaidli completed a PhD in "Functional Imaging and Texture Analysis in Radiotherapy Planning (FiNiTe RT)". This project was in partnership with The Royal Surrey Hospital and Alliance Medical Limited
Postgraduate research supervision
Greg Smyth at the Royal Marsden NHS Foundation Trust and Institute of Cancer Research is research for a PhD in "Dynamic couch rotation during volumetric modulated arc therapy (DCR-VMAT)". His supervisors and Dr James Bedford and Prof Jeff Bamber at RMH/ICR and me.