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Metabolomics core facility

Metabolomics, or metabonomics, refers to the measurement of metabolites (compounds with a molecular mass < 1000 daltons) in biological materials such as blood, urine, cells. 

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About us

In the Faculty we are able to perform both untargeted and targeted metabolomics. Untargeted metabolomics, also referred to as global metabolite profiling, is used to identify metabolic pathways that can be linked to biological mechanisms or clinical outcomes. Targeted metabolomics focuses on specific compounds (or pathways) and is usually more quantitative than untargeted metabolomics. 

The FHMS metabolomics facility contains 2 liquid chromatography mass spectrometers (LC-MS) and one gas chromatography MS (GC-MS).

We routinely use targeted LC-MS metabolomics  to investigate 24 h rhythms, circadian and sleep/wake processing in a range of species, including humans. Our targeted method (AbsoluteIDQ® p180 Kit, Biocrates) measures amino acids, biogenic amines, acylcarnitines, glycerophospholipids and sphingolipids.  

Instruments

Enquiries

Please contact Dr Dovile Lingaityte regarding analyses (d.lingaityte@surrey.ac.uk). 

People

Academic lead

Debra J. Skene profile image

Professor Debra Skene

Professor of Neuroendocrinology; Section Lead Chronobiology

Support staff

Dr Dovile Lingaityte

Senior Research Technician (LC-MS), Chronobiology

Contact us

  • Phone: +44 (0)1483 686700

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Address

School of Biosciences and Medicine
University of Surrey
Guildford
Surrey
GU2 7XH