I studied biochemistry and obtained a PhD at the University of Lyon, France, in 2000, working on DNA immunization as a therapeutic approach against chronic Hepatitis B Virus infection, in collaboration with the Institut National de la Sante et Recherche Medicale (INSERM), Lyon, France. I proceeded to work on novel vaccine development and cellular immunity against Hepatitis C Virus chronic infection at the Biomedical Primate Research Center, The Netherlands.
In 2007 I joined the Jenner Institute at the University of Oxford as a senior immunologist, to work on improvements of vaccine vectors against malaria. I then moved to the Oxford Vaccine Group in 2010, bringing my expertise of viral vectored vaccine platform and preclinical research, and became Associate Professor in Vaccinology. I started, developed and led the Novel Vaccine Development team involved in the creation, design, preclinical and early clinical studies of new and improved vaccines against bacterial diseases and infectious diseases affecting children. My research activities, funded by the Medical research Council, Innovate UK, the Oxford Biomedical Research Centre, and several charities, include the conception, design, pre-clinical and early clinical development of new and improved vaccines against bacterial infections such as caspular group B meningococcus, plague, Q fever, enteric fever, pertussis, gonorrhoea and Respiratory Syncitial Virus.
In 2021 I joined the University of Surrey as Professor of Vaccinology.
Areas of specialism
In the media
My research interest are in vaccine development from design and preclinical studies to early clinical development. I have expertise in different vaccine platforms and approaches and seek to adapt those to the target pathogen and to the target population, with a focus on OneHealth, anti-microbial resistance and vulnerable populations (children, elderly and low-and-middle-income countries).
PhD project led by Dr Elma Tchilian, The Pirbright Institute
PhD project led by Dr Chris Netherton, The Pirbright Institute
Vaccine development against gonorrhoea, led by Prof Calman MacLennan, The Jenner Institute, University of Oxford
Indicators of esteem
Jenner Institute Investigator (since 2014)
Visiting scientist at The University of Oxford (since 2021)