
Dr Lisa Holbrook
Academic and research departments
School of Veterinary Medicine, Faculty of Health and Medical Sciences.About
Biography
Lisa graduated with a degree in Biological Sciences in 2005 and a PhD in Protein Biochemistry and Cell Biology in 2010 from the University of Reading. The focus of Lisa's PhD thesis was to identify and characterise novel thiol isomerase enzymes in platelets. Following her PhD, Lisa was a successful postdoctoral researcher with roles at Imperial College London, Oxford University, University of Reading and King's College London. In these roles she continued to develop her interests in how platelet function is controlled by redox modulation. Lisa joined the University of Surrey as a lecturer in 2022.
University roles and responsibilities
- PBL Coordinator
My qualifications
ResearchResearch interests
Lisa's research focuses on understanding how redox proteins such as thiol isomerases and NADPH Oxidases regulate the development and progression of disease in humans and animals. Much of Lisa's work to date has focused on investigating the impact of these proteins in the regulation of platelet activation, platelet signalling and thrombosis. Her current research aims to explore how these platelet-secreted proteins regulate cell migration and metastasis in cancer.
Indicators of esteem
Editor's Awards finalist, JTH 2017.
ISTH 2009 Young Investigator Award Recipient.
Research interests
Lisa's research focuses on understanding how redox proteins such as thiol isomerases and NADPH Oxidases regulate the development and progression of disease in humans and animals. Much of Lisa's work to date has focused on investigating the impact of these proteins in the regulation of platelet activation, platelet signalling and thrombosis. Her current research aims to explore how these platelet-secreted proteins regulate cell migration and metastasis in cancer.
Indicators of esteem
Editor's Awards finalist, JTH 2017.
ISTH 2009 Young Investigator Award Recipient.
Publications
without altering bleeding times.
enhance antiplatelet effects.
association of phosphatidylinositol 3-kinase with Grb-2-associated binding protein-1 and linker for activation of T cells.
protein Hsp47 is exposed on the surface of activated human platelets.