Dr Lucy Cogdell-Brooke


My research project

My qualifications

2014
2:1, BSc Psychology
University of Bath
2017-09-01
Distinction, MSc Research Methods in Psychology
University of Surrey
2021
PhD
University of Surrey

Affiliations and memberships

British Neuropsychological Society
Full member of the British Neuropsychological Society
British Psychological Society
Graduate Member of the British Psychological Society

Research

Research interests

Research projects

Research collaborations

My publications

Publications

Lucy Cogdell-Brooke, Sara Stampacchia, Elizabeth Jefferies, Inês R Violante, Hannah E Thompson (2020)Consistently inconsistent: Multimodal episodic deficits in semantic aphasia, In: Neuropsychologia140107392 Elsevier Ltd

Semantic Aphasia (SA) patients have difficulty accessing semantic knowledge in both verbal and non-verbal tasks appropriately for the current context. Automatically activated semantic knowledge overwhelms the system, because it is no longer able to inhibit interference from dominant meanings in order to select weaker alternatives. Episodic memory, like semantic memory, requires control to select relevant memories amongst competing episodes. For example, our memory for what we ate for breakfast last Saturday is affected by competition from numerous other breakfast meals eaten on other days. Where one is unable to guide retrieval, we may rely on automatically activated knowledge about “breakfast foods”, and therefore experience false memories. Brain systems that support semantic control are also implicated in episodic control, and therefore deficits in semantic control are likely to cause more widespread problems. Despite this, nearly all research to date focuses on semantic performance alone. This study explored the impact of this semantic impairment on episodic recall. We used a verbal and non-verbal episodic memory task: participants remembered nursery rhymes in the verbal condition and logos and their associated products in the visual condition (e.g. bowl of cereal and coco-pops). For both tasks, we manipulated a) congruency with pre-existing knowledge (e.g. expectancy of trials: baa baa blackbuild – instead of sheep) and b) whether these trial types were blocked by congruency or mixed, as well as (c) distractor strength. If SA patients experience overwhelming automatic activation, they should find incongruent items more difficult to suppress, particularly when presented in an unpredictable task format. A total of 13 SA patients were compared to 33 controls across three experiments. In line with our predictions, SA patients found it more difficult to retrieve episodic memories which were in conflict with pre-existing semantic knowledge. This was true across modalities. Moreover, these deficits were accentuated when the congruency was presented in a mixed fashion, and so unpredictable across trials. Evidence of these episodic control impairments in SA cases supports the idea of a shared mechanism for semantic and episodic memory control. •Deficits of control in semantic aphasia affect episodic retrieval.•Semantic aphasia patients demonstrate an over-reliance on automatic activation.•Patients will select semantically related information over correct newly encoded information.•They display inconsistent performance across experiments which probe similar processes.•A shared mechanism may exist between semantic and episodic retrieval.

Lucy S Cogdell‐Brooke, Paul T Sowden, Inês R Violante, Hannah E Thompson (2020)A meta‐analysis of functional magnetic resonance imaging studies of divergent thinking using activation likelihood estimation, In: Human Brain Mapping41(17)pp. 5057-5077 John Wiley & Sons, Inc

There are conflicting findings regarding brain regions and networks underpinning creativity, with divergent thinking tasks commonly used to study this. A handful of meta‐analyses have attempted to synthesise findings on neural mechanisms of divergent thinking. With the rapid proliferation of research and recent developments in fMRI meta‐analysis approaches, it is timely to reassess the regions activated during divergent thinking creativity tasks. Of particular interest is examining the evidence regarding large‐scale brain networks proposed to be key in divergent thinking and extending this work to consider the role of the semantic control network. Studies utilising fMRI with healthy participants completing divergent thinking tasks were systematically identified, with 20 studies meeting the criteria. Activation Likelihood Estimation was then used to integrate the neuroimaging results across studies. This revealed four clusters: the left inferior parietal lobe; the left inferior frontal and precentral gyrus; the superior and medial frontal gyrus and the right cerebellum. These regions are key in the semantic network, important for flexible retrieval of stored knowledge, highlighting the role of this network in divergent thinking. A meta‐analysis of fMRI studies into divergent thinking, with a comparison to default mode, multiple demand and semantic control networks. This found four clusters; the left inferior parietal lobe; the left inferior frontal and precentral gyrus; the superior and medial frontal gyrus and the right cerebellum. The largest overlap is with the semantic control network, highlighting the role of this network in divergent thinking.

Lucy Cogdell-Brooke (2020)Consistently inconsistent: Multimodal episodic deficits in semantic aphasia, In: Neuropsychologia140107392 Elsevier

Semantic Aphasia (SA) patients have difficulty accessing semantic knowledge in both verbal and non-verbal tasks appropriately for the current context. Automatically activated semantic knowledge overwhelms the system, because it is no longer able to inhibit interference from dominant meanings in order to select weaker alternatives. Episodic memory, like semantic memory, requires control to select relevant memories amongst competing episodes. For example, our memory for what we ate for breakfast last Saturday is affected by competition from numerous other breakfast meals eaten on other days. Where one is unable to guide retrieval, we may rely on automatically activated knowledge about “breakfast foods”, and therefore experience false memories. Brain systems that support semantic control are also implicated in episodic control, and therefore deficits in semantic control are likely to cause more widespread problems. Despite this, nearly all research to date focuses on semantic performance alone. This study explored the impact of this semantic impairment on episodic recall. We used a verbal and non-verbal episodic memory task: participants remembered nursery rhymes in the verbal condition and logos and their associated products in the visual condition (e.g. BOWL OF CEREAL and COCO-POPS). For both tasks, we manipulated a) congruency with pre-existing knowledge (e.g. expectancy of trials: BAA BAA BLACK BUILD – instead of SHEEP) and b) whether these trial types were blocked by congruency or mixed, as well as (c) distractor strength. If SA patients experience overwhelming automatic activation, they should find incongruent items more difficult to suppress, particularly when presented in an unpredictable task format. A total of 13 SA patients were compared to 33 controls across three experiments. In line with our predictions, SA patients found it more difficult to retrieve episodic memories which were in conflict with pre-existing semantic knowledge. This was true across modalities. Moreover, these deficits were accentuated when the congruency was presented in a mixed fashion, and so unpredictable across trials. Evidence of these episodic control impairments in SA cases supports the idea of a shared mechanism for semantic and episodic memory control.