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Professor Nick Bacon


Professor of Surgical Oncology

My publications

Publications

Bacon NJ (2013)Primary Hyperparathyroidism, In: Small Animal Soft Tissue Surgerypp. 1-16
© 2013 John Wiley & Sons, Ltd.The parathyroid glands in dogs and cats are tan-colored ovoid structures closely associated with each thyroid gland. Parathyroid hormone (PTH) release is controlled by calcium receptors on the chief cells in the parathyroid glands in response to hypocalcemia. PTH has a short half-life (3-5 min) in serum and so a steady rate of secretion is necessary to maintain serum PTH concentrations. Natural variations in PTH concentration occur in healthy dogs. Exploratory surgery with parathyroidectomy in dogs with primary hyperparathyroidism serves as both a diagnostic test and definitive therapy. Surgery should be advocated to reduce the risk of urolithiasis and urinary tract infection, as well as improving the clinical signs seen with hypercalcemia such as polydipsia, polyuria, weakness, and decreased appetite. Surgical excision alone is the most widely performed treatment for primary hyperparathyroidism and a cure rate of 94% is reported if all autonomously functioning parathyroid tissue is removed.
Kirkby KA, Wheeler JL, Farese JP, Ellison GW, Bacon NJ, Sereda CW, Lewis DD (2009)Vacuum-Assisted Wound Closure: Application and Mechanism of Action, In: COMPENDIUM-CONTINUING EDUCATION FOR VETERINARIANS31(12)pp. 568-+ VETERINARY LEARNING SYSTEMS
Day MJ, Henderson SM, Belshaw Z, Bacon NJ (2004)An immunohistochemical investigation of 18 cases of feline nasal lymphoma, In: JOURNAL OF COMPARATIVE PATHOLOGY130(2-3)pp. 152-161 ACADEMIC PRESS LTD ELSEVIER SCIENCE LTD
Kirkby KA, Wheeler JL, Farese JP, Ellison GW, Bacon NJ, Sereda CW, Lewis DD (2010)Vacuum-assisted wound closure: Clinical applications, In: Compendium: Continuing Education For Veterinarians32(3)
Vacuum-assisted closure (VAC) is a wound management system that exposes a wound bed to local negative pressure to promote healing. Benefits of VAC therapy include removal of fluid from the extravascular space, improved circulation, enhanced granulation tissue formation, and increased bacterial clearance. VAC therapy has been used extensively in human patients to treat a variety of acute and chronic wound conditions. This article reviews the use of VAC therapy in a variety of wound conditions and describes our experiences with using VAC therapy in dogs and cats at the University of Florida. © Copyright 2010 MediMedia Animal Health.
Bacon NJ, Anderson DM, Baines EA, White RAS (2002)Post-traumatic para-ureteral urinoma (uriniferous pseudocyst) in a cat, In: VETERINARY AND COMPARATIVE ORTHOPAEDICS AND TRAUMATOLOGY15(2)pp. 123-126 SCHATTAUER GMBH-VERLAG MEDIZIN NATURWISSENSCHAFTEN
Kishi EN, Holmes SP, Abbott JR, Bacon NJ (2014)Functional metastatic parathyroid adenocarcinoma in a dog, In: CANADIAN VETERINARY JOURNAL-REVUE VETERINAIRE CANADIENNE55(4)pp. 383-388 CANADIAN VET MED ASSOC
Gear RNA, Bacon NJ, Langley-Hobbs S, Watson PJ, Woodger N, Herrtage ME (2006)Panniculitis, polyarthritis and osteomyelitis associated with pancreatic neoplasia in two dogs, In: JOURNAL OF SMALL ANIMAL PRACTICE47(7)pp. 400-404 BLACKWELL PUBLISHING
Covey JL, Farese JP, Bacon NJ, Schallberger SP, Amsellem P, Cavanaugh RP, Milner RJ (2014)Stereotactic radiosurgery and fracture fixation in 6 dogs with appendicular osteosarcoma., In: Vet Surg43(2)pp. 174-181
OBJECTIVE: To evaluate clinical outcome of dogs with appendicular osteosarcoma (OSA) treated with stereotactic radiosurgery (SRS) and subsequent internal fixation of a pathologic fracture. STUDY DESIGN: Retrospective case series. ANIMALS: Dogs with spontaneous-occurring appendicular OSA (n = 6). METHODS: Medical records (May 2002-January 2008) of dogs that had SRS for appendicular OSA were reviewed. Dogs were included if they had a pathologic fracture either before or after SRS and were treated with internal fixation. Signalment, history, physical examination findings, clinicopathologic data, diagnostic imaging findings, biopsy results, surgical complications, number of surgeries, adjuvant therapy, development of metastatic disease and cause of death were recorded. RESULTS: Six dogs met the inclusion criteria. Two dogs had a pathologic fracture at admission and 4 dogs developed a fracture after SRS with a mean ± SD time to fracture development of 6.25 ± 1.65 months. The first 3 fractures were repaired using an open approach and the latter three using minimally invasive percutaneous osteosynthesis (MIPO). Infection occurred in 5 dogs and implant failure in 3. Limb function was subjectively assessed as good in all dogs when the implants were stable and infections were subclinical. Survival times ranged from 364-897 days; 1 dog was lost to follow-up. CONCLUSIONS: Fracture repair using internal fixation should be considered a viable limb-sparing alternative for pathologic fractures that have been treated with SRS.
Bacon N, Souza CHDM, Franz S (2016)Total cysto-prostatectomy: Technique description and results in 2 dogs, In: CANADIAN VETERINARY JOURNAL-REVUE VETERINAIRE CANADIENNE57(2)pp. 141-146 CANADIAN VET MED ASSOC
Boston SE, Bacon NJ, Culp WTN, Bhandal J, Bruce C, Cavanaugh RP, Hamilton MH, Lincoln JD, Liptak JM, Scharvogel S (2011)Outcome after Repair of a Sarcoma-Related Pathologic Fracture in Dogs: A Veterinary Society of Surgical Oncology Retrospective Study, In: VETERINARY SURGERY40(4)pp. 431-437 WILEY-BLACKWELL
Parfitt SL, Milner RJ, Salute ME, Hintenlang DE, Farese JP, Bacon NJ, Bova FJ, Rajon DA, Lurie DM (2011)Radiosensitivity and capacity for radiation-induced sublethal damage repair of canine transitional cell carcinoma (TCC) cell lines, In: VETERINARY AND COMPARATIVE ONCOLOGY9(3)pp. 232-240 WILEY-BLACKWELL
Kim SE, Giglio RF, Reese DJ, Reese SL, Bacon NJ, Ellison GW (2013)Comparison of computed tomographic angiography and ultrasonography for the detection and characterization of portosystemic shunts in dogs., In: Vet Radiol Ultrasound54(6)pp. 569-574
The purpose of this retrospective study was to compare the accuracy of computed tomographic angiography (CTA) and abdominal ultrasonography in detecting and characterizing portosystemic shunts (PSS) in dogs. Medical records of 76 dogs that underwent CTA and/or abdominal ultrasonography suspected to have PSS were reviewed. Presence or absence, and characterization of PSS (when present) on CTA were reviewed by a board-certified veterinary radiologist that was blinded to the clinical findings. The abdominal ultrasonography findings were reviewed from the medical records. Visualization and description of the origin and insertion of PSS on CTA and abdominal ultrasonography were related with laboratory, surgical, or mesenteric portographic confirmation of the presence or absence of PSS. The sensitivity for detection of PSS with CTA (96%) was significantly higher than abdominal ultrasonography (68%; P < 0.001). The specificities for CTA and abdominal ultrasonography were 89% and 84%, respectively (P = 0.727). Computed tomographic angiography detected the correct origin in 15 of 16 dogs and correct insertion in 15 of 16 dogs with congenital PSS. Abdominal ultrasonography detected the correct origin in 24 of 30 dogs and correct insertion in 20 of 33 dogs with congenital PSS. Multiple acquired PSS were seen in four of five dogs and in one of six dogs on CTA and abdominal ultrasonography, respectively. Computed tomographic angiography was 5.5 times more likely to correctly ascertain the presence or absence of PSS when compared to abdominal ultrasonography (P = 0.02). Findings indicated that CTA is a noninvasive diagnostic modality that is superior to abdominal ultrasonography for the detection and characterization of PSS in dogs.
McCally RE, Kim SE, Bacon NJ, Winter MD, Cords AA, Conway JA (2012)Surgical Management of a Subepiglottic Thyroglossal Duct Cyst in a Dog, In: JOURNAL OF THE AMERICAN ANIMAL HOSPITAL ASSOCIATION48(3)pp. 198-202 AMER ANIMAL HOSPITAL ASSOC
Rubin JA, Kim SE, Bacon NJ (2013)Traumatic tympanic bulla fracture, In: JOURNAL OF SMALL ANIMAL PRACTICE54(11)pp. 605-609 WILEY-BLACKWELL
Wirth KA, Kow K, Salute ME, Bacon NJ, Milner RJ (2014)In vitro effects of Yunnan Baiyao on canine hemangiosarcoma cell lines., In: Vet Comp Oncol
Yunnan Baiyao is a Chinese herbal medicine that has been utilized for its anti-inflammatory, haemostatic, wound healing and pain relieving properties in people. It has been utilized in the veterinary profession to control bleeding in dogs with hemangiosarcoma (HSA) and has been anecdotally reported to prolong survival times in dogs with this neoplasm. This study evaluated the in vitro activity of Yunnan Baiyao against three canine HSA cell lines after treatment with increasing concentrations of Yunnan Baiyao (50, 100, 200, 400, 600 and 800 µg mL(-1) ) at 24, 48 and 72 h. Mean half maximum inhibitory concentration (IC50 ) at 72 h for DEN, Fitz, SB was 369.9, 275.9 and 325.3 µg mL(-1) , respectively. Caspase-3/7 activity increased in correlation with the IC50 in each cell line which was confirmed by the terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL, APO-BRDU Kit; BD Biosciences, San Jose, CA, USA) assay. VEGF in cell supernatant was also quantified. Overall, the study found that Yunnan Baiyao causes dose and time dependent HSA cell death through initiation of caspase-mediated apoptosis, which supports future studies involving Yunnan Baiyao.
Cavanaugh RP, Farese JP, Bacon NJ, Lurie DM, Milner RJ (2011)Oronasal Fistula Repair Utilizing a Temporalis Muscle Flap in a Dog with Severe Trismus, In: JOURNAL OF THE AMERICAN ANIMAL HOSPITAL ASSOCIATION47(6)pp. 447-454 AMER ANIMAL HOSPITAL ASSOC
Thieman KM, Kirkby KA, Flynn-Lurie A, Grooters AM, Bacon NJ (2011)Diagnosis and treatment of truncal cutaneous pythiosis in a dog, In: JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION239(9)pp. 1232-1235 AMER VETERINARY MEDICAL ASSOC
Fahey CE, Milner RJ, Kow K, Bacon NJ, Salute ME (2013)Apoptotic effects of the tyrosine kinase inhibitor, masitinib mesylate, on canine osteosarcoma cells, In: ANTI-CANCER DRUGS24(5)pp. 519-526 LIPPINCOTT WILLIAMS & WILKINS
Kubicek L, Milner R, An Q, Kow K, Chang M, Cooke K, Fox L, Farese J, Bacon N, Lurie D (2016)OUTCOMES AND PROGNOSTIC FACTORS ASSOCIATED WITH CANINE SINONASAL TUMORS TREATED WITH CURATIVE INTENT CONE-BASED STEREOTACTIC RADIOSURGERY (1999-2013), In: VETERINARY RADIOLOGY & ULTRASOUND57(3)pp. 331-340 WILEY-BLACKWELL
Belshaw Z, Bacon NJ, Foale RD, Mannion PM, Reuter R (2005)Pancreatic mixed acinar-endocrine carcinoma in a dog., In: Vet Comp Oncol3(3)pp. 145-148
A 10.5-year-old crossbreed dog was presented with a history of hypoglycaemic episodes and elevated serum insulin concentration. A pancreatic mass was removed at surgery along with an enlarged draining lymph node. An unresectable hepatic nodule was also present. Immunohistochemistry confirmed the pancreatic and lymph node masses as functional mixed acinar-endocrine carcinoma, previously unreported in domestic species. Persistent hypoglycaemia and hyperinsulinaemia post-operatively was highly suggestive of the hepatic mass being a functional metastasis. The dog was managed on prednisolone and remained asymptomatic 9 months post-operatively. This tumour type has only been rarely reported in human patients and may highlight the need for more rigorous immunohistochemical staining of pancreatic masses in veterinary species to identify the prevalence of this tumour type.
Jeffery ND, Talbot CE, Smith PM, Bacon NJ (2006)Acquired idiopathic laryngeal paralysis as a prominent feature of generalised neuromuscular disease in 39 dogs, In: VETERINARY RECORD158(1)pp. 17-21 BRITISH VETERINARY ASSOC
Guérios SD, Silva DM, Souza CH, Bacon NJ (2015)Surgical placement and management of jugular vascular access ports in dogs and cats: Description of technique<sup>¤</sup>, In: Revista Colombiana de Ciencias Pecuarias28(3)pp. 165-171
© 2015, Universidad de Antioquia. All rights reserved.Background: vascular access ports (VAPs) are designed to allow repeated access to the vascular system with minimum patient distress. Objective: to describe the surgical technique, care and complications of jugular VAPs currently used at the Veterinary Oncology Service of the University of Florida Small Animal Hospital. Conclusion: the VAPs can remain in site for long terms (months) with minimum complications, and its placement is a reliable technique that should be considered by veterinarians, particularly for a long-term treatment.
Novella L, Carobbi B, Bacon NJ, White RAS (2008)Hypobaric intrathecal anaesthesia for partial hemipelvectomy in a dog, In: VETERINARY AND COMPARATIVE ORTHOPAEDICS AND TRAUMATOLOGY21(1)pp. 89-93 SCHATTAUER GMBH-VERLAG MEDIZIN NATURWISSENSCHAFTEN
Schmidt AF, Groenwold RHH, Amsellem P, Bacon N, Klungel OH, Hoes AW, de Boer A, Kow K, Maritato K, Kirpensteijn J, Nielen M (2016)Which dogs with appendicular osteosarcoma benefit most from chemotherapy after surgery? Results from an individual patient data meta-analysis, In: PREVENTIVE VETERINARY MEDICINE125pp. 116-125 ELSEVIER SCIENCE BV
Coomer AR, Bacon N (2009)Primary anastomosis of segmental external auditory canal atresia in a cat, In: JOURNAL OF FELINE MEDICINE AND SURGERY11(10)pp. 864-868 SAGE PUBLICATIONS LTD
Sissener TR, Bacon NJ, Friend E, Anderson DM, White RAS (2006)Combined clotrimazole irrigation and depot therapy for canine nasal aspergillosis, In: JOURNAL OF SMALL ANIMAL PRACTICE47(6)pp. 312-315 BLACKWELL PUBLISHING
Boston SE, Duerr F, Bacon N, Larue S, Ehrhart EJ, Withrow S (2007)Intraoperative radiation for limb sparing of the distal aspect of the radius without transcarpal plating in five dogs., In: Vet Surg36(4)pp. 314-323
OBJECTIVES: To evaluate intraoperative irradiation (IORT) as a method of limb spare with preservation of the radiocarpal joint. STUDY DESIGN: Prospective case series. ANIMALS: Dogs (n=5) with stage II sarcoma of the distal aspect of the radius. METHODS: A bone segment containing the tumor was isolated surgically, treated by IORT, reimplanted, and secured by internal fixation. In 1 dog, the postradiation tumor bed was curetted and filled with bone cement. Dogs were administered alternating adriamycin and carboplatin starting 2 weeks after IORT and monitored at regular intervals. RESULTS: Four dogs had osteosarcoma and 1 had undifferentiated sarcoma. Implant failure (n=3), deep tissue infection (3), and pathologic fracture (3) resulted in amputation (3) or pancarpal plating (2). The dog with undifferentiated sarcoma was euthanatized because of suspected tumor recurrence 4 months postoperatively. Osteotomy healing was documented by radiography (1), histopathology (2), or by direct observation (2). CONCLUSIONS: A technique for limb-sparing surgery of the distal portion of the radius in dogs using IORT had advantages include healing of the autograft and a source for a perfectly fitting autograft but did not appear to offer any advantage with respect to infection rate. Long-term preservation of the radiocarpal joint was not successful. CLINICAL RELEVANCE: It was not possible to preserve the function of the radiocarpal joint and so this technique cannot be recommended currently. Further study is needed to evaluate whether or not IORT can be considered in combination with pancarpal plating and possibly curettage and cementation of the tumor to prevent subchondral bone collapse.
Farese JP, Bacon NJ, Ehrhart NP, Bush J, Ehrhart EJ, Withrow SJ (2008)Oesophageal leiomyosarcoma in dogs: surgical management and clinical outcome of four cases, In: VETERINARY AND COMPARATIVE ONCOLOGY6(1)pp. 31-38 BLACKWELL PUBLISHING
Coomer A, Farese J, Milner R, Liptak J, Bacon N, Lurie D (2009)Radiation therapy for canine appendicular osteosarcoma, In: VETERINARY AND COMPARATIVE ONCOLOGY7(1)pp. 15-27 WILEY-BLACKWELL PUBLISHING, INC
Bacon NJ, Ehrhart NR, Dernell WS, Lafferty M, Withrow SJ (2008)Use of alternating administration of carboplatin and doxorubicin in dogs with microscopic metastases after amputation for appendicular osteosarcoma: 50 cases (1999-2006), In: JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION232(10)pp. 1504-1510 AMER VETERINARY MEDICAL ASSOC
Bacon NJ, Dernell WS, Ehrhart N, Powers BE, Withrow SJ (2007)Evaluation of primary re-excision after recent inadequate resection of soft tissue sarcomas in dogs: 41 cases (1999-2004), In: JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION230(4)pp. 548-554 AMER VETERINARY MEDICAL ASSOC
Bova FJ, Rajon DA, Parfitt SL, Milner RJ, Salute ME, Farese JP, Bacon NJ (2010)RADIOSENSTIVITY AND CAPACITY FOR RADIATION-INDUCED SUBLETHAL DAMAGE REPAIR OF CANINE TRANSITIONAL CELL CARCINOMA CELL LINES, In: JOURNAL OF VETERINARY INTERNAL MEDICINE24(3)pp. 675-675 WILEY-BLACKWELL PUBLISHING, INC
Covey JL, Farese JP, Bacon NJ, Schallberger SP, Amsellem P, Cavanaugh RP, Milner RJ (2014)Stereotactic Radiosurgery and Fracture Fixation in 6 Dogs With Appendicular Osteosarcoma, In: VETERINARY SURGERY43(2)pp. 174-181 WILEY-BLACKWELL
Guerios SD, Silva DM, Souza CHM, Bacon NJ (2015)Surgical placement and management of jugular vascular access ports in dogs and cats: description of technique, In: REVISTA COLOMBIANA DE CIENCIAS PECUARIAS28(3)pp. 265-271 UNIV ANTIOQUIA, FAC CIENCIAS AGRARIAS
Dennis MM, McSporran KD, Bacon NJ, Schulman FY, Foster RA, Powers BE (2011)Prognostic Factors for Cutaneous and Subcutaneous Soft Tissue Sarcomas in Dogs, In: VETERINARY PATHOLOGY48(1)pp. 73-84 SAGE PUBLICATIONS INC
Bacon NJ, White RAS (2003)Extrahepatic biliary tract surgery in the cat: a case series and review, In: JOURNAL OF SMALL ANIMAL PRACTICE44(5)pp. 231-235 BRITISH VETERINARY ASSOC
Webster JD, Dennis MM, Dervisis N, Heller J, Bacon NJ, Bergman PJ, Bienzle D, Cassali G, Castagnaro M, Goldschmidt MH, Cullen J, Esplin DG, Pena L, Hahn KA, Henry CJ, Hellmen E, Kamstock D, Kirpensteijn J, Kitchell BE, McEntee M, Amorim RL, Lenz SD, Lipscomb TP, McGill LD, McKnight CA, McManus PM, Moore AS, Moore PF, Moroff SD, Scase T, Nakayama H, Northrup NC, Sarli G, Sorenmo K, Schulman FY, Shoieb AM, Smedley RC, Spangler WL, Teske E, von Euler H, Thamm DH, Valli VE, Vernau W, Withrow SJ, Weisbrode SE, Yager J, Kiupel M (2011)Recommended Guidelines for the Conduct and Evaluation of Prognostic Studies in Veterinary Oncology, In: VETERINARY PATHOLOGY48(1)pp. 7-18 SAGE PUBLICATIONS INC
Wypij JM, Bacon NJ, Culp WTN, Ehrhart NP, Powers BE, Stryhn H, Farese JP, Amsellem PM, Selmic LE (2014)Appendicular osteosarcoma in small-breed dogs: 51 cases (1986-2011), In: JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION245(2)pp. 203-210 AMER VETERINARY MEDICAL ASSOC
Phelps HA, Kuntz CA, Milner RJ, Powers BE, Bacon NJ (2011)Radical excision with five-centimeter margins for treatment of feline injection-site sarcomas: 91 cases (1998-2002), In: JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION239(1)pp. 97-106 AMER VETERINARY MEDICAL ASSOC
Bacon NJ, Gilbert RL, Bostock DE, White RAS (2003)Total ear canal ablation in the cat: indications, morbidity and long-term survival, In: JOURNAL OF SMALL ANIMAL PRACTICE44(10)pp. 430-434 BRITISH VETERINARY ASSOC
Bacon NJ, Oni O, White RAS (2002)Treatment of urethral sphincter mechanism incompetence in 11 bitches with a sustained-release formulation of phenylpropanolamine hydrochloride, In: VETERINARY RECORD151(13)pp. 373-376 BRITISH VETERINARY ASSOC
Cuddy LC, Bacon NJ, Coomer AR, Jeyapaul CJ, Sheppard BJ, Winter MD (2010)Excision of a congenital laryngeal cyst in a five-month-old dog via a lateral extraluminal approach, In: JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION236(12)pp. 1328-1333 AMER VETERINARY MEDICAL ASSOC
Bray JP, Worley DR, Henderson RA, Boston SE, Mathews KG, Romanelli G, Bacon NJ, Liptak JM, Scase TJ (2014)Hemipelvectomy: Outcome in 84 Dogs and 16 Cats. A Veterinary Society of Surgical Oncology Retrospective Study, In: VETERINARY SURGERY43(1)pp. 27-37 WILEY-BLACKWELL
Chang MN, Jiang Y, Withrow SJ, Farese JP, Kirpensteijn J, Kik M, Bacon NJ, Waltman SS, Seguin B, Kent M, Liptak J, Straw R (2009)Biologic Behavior and Clinical Outcome of 25 Dogs with Canine Appendicular Chondrosarcoma Treated by Amputation: A Veterinary Society of Surgical Oncology Retrospective Study, In: VETERINARY SURGERY38(8)pp. 914-919 WILEY-BLACKWELL PUBLISHING, INC
Risselada M, Ellison GW, Bacon NJ, Polyak MMR, van Gilder J, Kirkby K, Kim SE (2010)Comparison of 5 Surgical Techniques for Partial Liver Lobectomy in the Dog for Intraoperative Blood Loss and Surgical Time, In: VETERINARY SURGERY39(7)pp. 856-862 WILEY-BLACKWELL
Kirkby K, Wheeler J, Farese J, Ellison G, Bacon N, Sereda C, Lewis D (2009)Surgical views: Vacuum-assisted wound closure: application and mechanism of action., In: Compend Contin Educ Vet31(12)pp. E1-E7
Vacuum-assisted closure (VAC) is a wound management therapy that creates local negative pressure over a wound bed to promote healing. Benefits of VAC therapy include removal of fluid from the extravascular space, improved circulation, enhanced granulation tissue formation, increased bacterial clearance, and hastening of wound closure. This article describes the mechanism of action of VAC therapy, reviews application techniques, and lists potential complications and contraindications.
Bacon NJ, Kamstock DA (2013)Spleenpp. 387-392
McGill LD, Miller MA, Mouser PJ, O'Toole D, Pool RR, Powers BE, Ramos-Vara JA, Roccabianca P, Ross AD, Sailasuta A, Sarli G, Scase TJ, Bacon NJ, Kamstock DA, Ehrhart EJ, Getzy DM, Straw RC, Rassnick KM, Moroff SD, Liu SM, McKnight CA, Amorim RL, Bienzle D, Dennis MM, Schulman FY, Shoieb AM, Singh K, Cassali GD, Cullen JM, Esplin DG, Foster RA, Goldschmidt MH, Gruber AD, Hellmen E, Spangler WL, Sledge D, Smedley RC, Smith KC, Steficek B, Stromberg PC, Valli VE, Yager J, Kiupel M, Lipscomb TP, Howerth EW, Labelle P, Lenz SD, Locke E (2011)Recommended Guidelines for Submission, Trimming, Margin Evaluation, and Reporting of Tumor Biopsy Specimens in Veterinary Surgical Pathology, In: VETERINARY PATHOLOGY48(1)pp. 19-31 SAGE PUBLICATIONS INC
Kligman KC, Kim SE, Winter MD, Bacon NJ, Krellner HL, Levy JK (2009)What Is Your Diagnosis?, In: JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION235(8)pp. 945-946 AMER VETERINARY MEDICAL ASSOC
Kirkby KA, Wheeler JL, Farese JP, Ellison GW, Bacon NJ, Sereda CW, Lewis DD (2010)Surgical views: Vacuum-assisted wound closure: clinical applications., In: Compend Contin Educ Vet32(3)pp. E1-E6
Vacuum-assisted closure (VAC) is a wound management system that exposes a wound bed to local negative pressure to promote healing. Benefits of VAC therapy include removal of fluid from the extravascular space, improved circulation, enhanced granulation tissue formation, and increased bacterial clearance. VAC therapy has been used extensively in human patients to treat a variety of acute and chronic wound conditions. This article reviews the use of VAC therapy in a variety of wound conditions and describes our experiences with using VAC therapy in dogs and cats at the University of Florida.
Batlivala TP, Bacon NJ, Avery AC, Barabas K, Gunn-Christie RG, Conway J, Avery PR (2010)Paraneoplastic T cell lymphocytosis associated with a thymoma in a dog, In: JOURNAL OF SMALL ANIMAL PRACTICE51(9)pp. 491-494 WILEY-BLACKWELL
Villedieu Erika J., Petite Audrey, Godolphin Janet, Bacon Nick Prevalence of pulmonary nodules suggestive of metastasis at presentation in dogs referred for treatment of cutaneous and subcutaneous soft tissue sarcomas: 146 cases (2014-2018)., In: JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION AMER VETERINARY MEDICAL ASSOC
Objective: The aim of this study was to investigate the prevalence of pulmonary nodules at presentation in cases of soft tissue sarcoma (STS) in dogs with no previous thoracic imaging. Animals: Client-owned dogs with a histologic diagnosis of STS. Procedures: Dogs were retrospectively included in this study if the first thoracic imaging performed was at the time of presentation to our referral center. De novo and recurrent tumors were included, and information regarding tumor grade, history (primary mass vs scar vs recurrence), duration, location and size was also collected. Results: One hundred and forty-six dogs were included. Routine staging was performed with computed tomography (131 dogs, 89.7%) or 3-view thoracic radiographs (15 dogs, 10.3%). STS were grade 1 in 55.5% of dogs, grade 2 in 27.4% and grade 3 in 17.1%. Pulmonary nodules suggestive of metastasis were present in 11.7% of cases overall and in 6.5%, 5.6% and 37.5% of grade 1, grade 2 and grade 3 STS cases, respectively. Tumor grade (low/intermediate versus high) and tumor duration (<= 3 months versus > 3 months) were significantly associated with presence of pulmonary nodules at presentation. Conclusions and Clinical Relevance: This is the first large study reporting prevalence of pulmonary nodules at presentation in dogs with STS having had no previous thoracic imaging. The prevalence of pulmonary nodules suggestive of metastasis at presentation is low (<7%) in grade 1 and grade 2 canine STS.
Bacon NJ, Farese JP (2013)Urinary Tractpp. 365-382
Risselada M, Polyak MMR, Ellison GW, Bacon NJ, Van Gilder JM, Coomer AR, Thieman KE (2010)Postmortem evaluation of surgery site leakage by use of in situ isolated pulsatile perfusion after partial liver lobectomy in dogs, In: AMERICAN JOURNAL OF VETERINARY RESEARCH71(3)pp. 262-267 AMER VETERINARY MEDICAL ASSOC
Kelsey KL, Kubicek LN, Bacon NJ, Torres T, Robertson SA (2017)Neuromuscular blockade and inspiratory breath hold during stereotactic body radiation therapy for treatment of heart base tumors in four dogs, In: Journal of the American Veterinary Medical Association250(2)pp. 199-204
CASE DESCRIPTION 4 dogs were examined because of pleural effusion and ventricular tachycardia, coughing and supraventricular tachycardia, appendicular osteosarcoma, and syncopal episodes. CLINICAL FINDINGS In all 4 dogs, a heart base tumor was identified by means of thoracic CT. TREATMENT AND OUTCOME In all 4 dogs, the heart base tumors were treated by means of stereotactic body radiation therapy. Dogs were anesthetized, and neuromuscular blockade was achieved with atracurium or vecuronium. A circle rebreathing system with 15 m (50 feet) of anesthetic tubing coursing through the vault wall was used to connect the patient to the anesthesia machine, which was located in the control room. After a brief period of hyperventilation, an inspiratory breath was held at 20 cm H2O for the duration of beam delivery. Each beam delivery lasted between 30 and 100 seconds. Immediately following the breath hold, assisted ventilation was resumed. Mean treatment delivery time for each patient was 26 minutes; mean total anesthesia time was 89 minutes. All patients recovered without complications. There was no evidence of hemoglobin desaturation or hypercapnia during the anesthetic procedure.