Dr Oleksiy Klymenko
Biography
My research focuses on the development and application of mathematical techniques for system and process modelling, design and optimisation in process systems engineering, physical chemistry and biochemistry. I was trained as an Applied Mathematician at Kharkov National University of Radio Electronics (Ukraine) where I obtained my BSc (2000) and MSc (2001) degrees before doing a D.Phil. in Computational Electrochemistry from the University of Oxford (2004) and a PhD in Computational Mathematics and Numerical Methods from Kharkov National University of Radioelectronics (2006). Since then I have held a number of researcher and senior scientist positions in Ukraine, France (Ecole Normale Supérieure, Paris) and the UK (Imperial College London) before joining the Department of Chemical and Process Engineering of the University of Surrey in 2016 as a Lecturer.
Research
Research interests
Model-based design and optimisation of process systems
Mathematical modelling in the natural and life sciences
Uncertainty quantification in process models, particularly Global Sensitivity Analysis
My teaching
I am currently module leader of two M-level modules:
- ENGM071 Process and Energy Integration (MSc only)
- ENGM214 Process Modelling and Simulation (MSc and Year 4 MEng)
and contribute the Numerical Methods component of the Year 2 BEng/MEng module
- ENG2113 Reaction Engineering and Numerical Methods
In the past, I have been involved in the delivery of a number of other undergraduate modules:
- ENG1083 Transferable Skills and Laboratory Skills
- ENG2120 Engineering Systems and Dynamics
- ENG3186 Energy and Industrial Systems
I regularly supervise Year 4 MEng and MSc research projects.
My publications
Publications
Costello Katherine M. (2020)A multi-scale analysis of the microbial response of Listeria to novel processing technologies, as affected by system (micro)structure and natural microflora University of Surrey
Hajizeinalibioki Sahar, Sebastia Saez Daniel, Klymenko Oleksiy, Arellano-Garcia Harvey (2018)Dull or bright you still get electric delight: A new approach to the design of all-weather panels, In: Friedl Anton, Klemeš Jiri K, Radl Stefan, Varbanov Petar S, Wallek Thomas (eds.), Computer Aided Chemical Engineering (Part of volume: 28th European Symposium on Computer Aided Process Engineering)43pp. 211-216 Elsevier
Oleinick A, Amatore C, Klymenko O, Svir I (2007)Mathematical modelling of nitric oxide release caused by exocytosis and determination of a stellate neuron activity function in rat brain, In: Nonlinear Analysis: Modelling and Control12(3)pp. 399-408
Amatore C, Klymenko OV, Oleinick A, Svir I (2007)In situ and on-line monitoring of hydrodynamic flow profiles in microfluidic channels based on microelectrochemistry: optimization of channel geometrical parameters for best performance of flow profile reconstruction., In: Chemphyschem8(12)pp. 1870-1874
Amatore C, Klymenko OV, Svir I (2006)Erratum: In situ and online monitoring of hydrodynamic flow profiles in microfluidic channels based upon microelectrochemistry: Optimization of electrode locations (Chemical Physics and Physical Chemistry (2006) 7, (482-487)), In: ChemPhysChem7(4)pp. 779-779
Klymenko OV, Amatore C, Svir I (2007)Time-dependent diffusion-migration at cylindrical and spherical microelectrodes: steady- and quasi-steady-state analytical solution can be used under transient conditions., In: Anal Chem79(16)pp. 6341-6347
Klymenko OV, Gavaghan DJ, Harriman KE, Compton RG (2002)Finite element simulation of electrochemically reversible, quasi-reversible and irreversible linear sweep voltammetry at the wall tube electrode, In: Journal of Electroanalytical Chemistry531(1)pp. 25-31
Klymenko O, Oleinick A, Amatore C, Svir I (2008)A new approach to the determination of the stellate neuron activity function in rat’s brain, In: Russian Journal of Physical Chemistry A82(9)pp. 1428-1433
Amatore C, Klymenko O, Svir I (2010)A new strategy for simulation of electrochemical mechanisms involving acute reaction fronts in solution: Application to model mechanisms, In: Electrochemistry Communications12(9)pp. 1165-1169
Amatore C, Klymenko OV, Svir I (2011)Replies to comments contained in "the True History of Adaptive Grids in Electrochemical Simulations" by D. Britz [Electrochim. Acta 56 (2011) 4420-4421], In: Electrochimica Acta56(11)pp. 4422-4423
Klymenko OV, Svir I, Amatore C (2010)Theoretical study of the EE reaction mechanism with comproportionation and different diffusivities of reactants, In: Electrochemistry Communications12(10)pp. 1378-1382
Wadhawan JD, Davies TJ, Clegg AD, Lawrence NS, Ball JC, Klymenko OV, Rees NV, Bethell D, Woolfall MP, France RR, Compton RG (2002)Photoelectrochemistry of bromonitrobenzenes: Mechanism and photoelectrochemically-induced halex reactions, In: Journal of Electroanalytical Chemistry533(1-2)pp. 33-70
Amatore C, Oleinick A, Klymenko OV, Svir I (2009)Capacitive and solution resistance effects on voltammetric responses at a disk microelectrode covered with a self-assembled monolayer in the presence of electron hopping., In: Anal Chem81(20)pp. 8545-8556
Amatore C, Oleinick A, Klymenko OV, Delacôte C, Walcarius A, Svir I (2008)Theory and simulation of diffusion-reaction into nano- and mesoporous structures. Experimental application to sequestration of mercury(II)., In: Anal Chem80(9)pp. 3229-3243
Klymenko OV, Oleinick AI, Svir I, Amatore C (2012)A new strategy for simulation of electrochemical mechanisms involving acute reaction fronts in solution under spherical or cylindrical diffusion, In: Russian Journal of Electrochemistry48(6)pp. 593-599
Klymenko OV, Oleinick AI, Amatore C, Svir I (2007)Reconstruction of hydrodynamic flow profiles in a rectangular channel using electrochemical methods of analysis, In: Electrochimica Acta53(3 SPEC)pp. 1100-1106
Amatore C, Klymenko OV, Oleinick AI, Svir I (2009)Electrochemical determination of flow velocity profile in a microfluidic channel from steady-state currents: numerical approach and optimization of electrode layout., In: Anal Chem81(18)pp. 7667-7676
Rees NV, Klymenko OV, Maisonhaute E, Coles BA, Compton RG (2003)The application of fast scan cyclic voltammetry to the high speed channel electrode, In: Journal of Electroanalytical Chemistry542pp. 23-32
Amatore C, Klymenko OV, Svir I (2012)Importance of correct prediction of initial concentrations in voltammetric scans: contrasting roles of thermodynamics, kinetics, and natural convection., In: Anal Chem84(6)pp. 2792-2798
Klymenko OV, Svir I, Oleinick A, Amatore C (2012)A novel approach to the simulation of electrochemical mechanisms involving acute reaction fronts at disk and band microelectrodes., In: Chemphyschem13(3)pp. 845-859
Banks CE, Klymenko OV, Compton RG (2003)Liquid-liquid processes and kinetics in acoustically emulsified media, In: Physical Chemistry Chemical Physics5(8)pp. 1652-1656
Amatore C, Oleinick AI, Klymenko OV, Svir I (2009)Theory of long-range diffusion of proteins on a spherical biological membrane: application to protein cluster formation and actin-comet tail growth., In: Chemphyschem10(9-10)pp. 1586-1592
Amatore C, Klymenko O, Svir I (2010)A new strategy for simulation of electrochemical mechanisms involving acute reaction fronts in solution: Principle, In: Electrochemistry Communications12(9)pp. 1170-1173
Platz MS, Svir IB, Oleinick AI, Klymenko OV (2003)KinFitSim: A powerful kinetic simulator and mechanism fitting tool, In: Proceedings of the International Conference on Advanced Optoelectronics and Lasers, CAOL1pp. 78-83
Shulyk VN, Klymenko OV, Svir IB (2008)Numerical solution of stiff ODEs describing complex homogeneous chemical processes, In: Journal of Mathematical Chemistry43(1)pp. 252-264
Rees NV, Klymenko OV, Coles BA, Compton RG (2002)The high speed channel electrode applied to heterogeneous kinetics: The oxidation of 1,4-phenylenediamines and related species in acetonitrile, In: Journal of Electroanalytical Chemistry534(2)pp. 151-161
Hyde ME, Klymenko OV, Compton RG (2002)The theory of electrodeposition in the presence of forced convection: Transport controlled nucleation of hemispheres, In: Journal of Electroanalytical Chemistry534(1)pp. 13-17
Giovanelli D, Lawrence NS, Klymenko OV, Jiang L, Jones TGJ, Compton RG (2003)The electrochemically initiated reaction of sulfide with N,N-diethyl-p-phenylenediamine in dimethylfonnamide. Part II: Implications for sensing strategies, In: Electroanalysis15(11)pp. 961-968
Kucherenko S., Klymenko Oleksiy, Shah N. (2017)Sobol' indices for problems defined in non-rectangular domains, In: Reliability Engineering & System Safety167pp. 218-231 Elsevier
Amatore C, Oleinick A, Klymenko OV, Thouin L, Servant L, Svir I (2007)Confocal microscopy imaging of electrochemiluminescence at double band microelectrode assemblies: numerical solution of the inverse optical problem., In: Chemphyschem8(11)pp. 1664-1676
Svir IB, Klymenko OV, Platz MS (2002)’KINFITSIM’–a software to fit kinetic data to a user selected mechanism., In: Comput Chem26(4)pp. 379-386
Rees NV, Klymenko OV, Compton RG, Oyama M (2002)The electro-oxidation of N,N-dimethyl-p-toluidine in acetonitrile: A microdisk voltammetry study, In: Journal of Electroanalytical Chemistry531(1)pp. 33-42
Rees NV, Wadhawan JD, Klymenko OV, Coles BA, Compton RG (2004)An electrochemical study of the oxidation of 1,3,5-Tris[4-[(3-methylphenyl)phenylamino]phenyl]benzene, In: Journal of Electroanalytical Chemistry563(2)pp. 191-202
Clegg AD, Rees NV, Klymenko OV, Coles BA, Compton RG (2004)Experimental validation of Marcus theory for outer-sphere heterogeneous electron-transfer reactions: the oxidation of substituted 1,4-phenylenediamines., In: Chemphyschem5(8)pp. 1234-1240
Klymenko OV, Compton RG (2004)Mass transport corrected Tafel analysis for electrochemically reversible systems of complex stoichiometry, In: Journal of Electroanalytical Chemistry571(2)pp. 207-210
Klymenko OV, Svir I, Amatore C (2013)New theoretical insights into the competitive roles of electron transfers involving adsorbed and homogeneous phases, In: Journal of Electroanalytical Chemistry688pp. 320-327
Wildgoose GG, Giovanelli D, Klymenko OV, Lawrence NS, Jiang L, Jones TGJ, Compton RG (2004)Electrochemical determination of sulfide at high temperatures via its electrochemically initiated reaction with diethyl-p-phenylenediamine in dimethylformamide, In: Electroanalysis16(5)pp. 337-344
Amatore C, Klymenko OV, Oleinick AI, Svir I (2009)Diffusion with moving boundary on spherical surfaces., In: Chemphyschem10(9-10)pp. 1593-1602
Klymenko OV, Evans RG, Hardacre C, Svir IB, Compton RG (2004)Double potential step chronoamperometry at microdisk electrodes: simulating the case of unequal diffusion coefficients, In: JOURNAL OF ELECTROANALYTICAL CHEMISTRY571(2)pp. 211-221 ELSEVIER SCIENCE SA
Chevallier FG, Klymenko OV, Jiang L, Jones TGJ, Compton RG (2005)Mathematical modelling and numerical simulation of adsorption processes at microdisk electrodes, In: Journal of Electroanalytical Chemistry574(2)pp. 217-237
Klymenko OV, Amatore C, Sun W, Zhou YL, Tian ZW, Svir I (2012)Theory and computational study of electrophoretic ion separation and focusing in microfluidic channels, In: Nonlinear Analysis: Modelling and Control17(4)pp. 431-447
Rees NV, Clegg AD, Klymenko OV, Coles BA, Compton RG (2004)Marcus theory for outer-sphere heterogeneous electron transfer: Predicting electron-transfer rates for quinones, In: Journal of Physical Chemistry B108(34)pp. 13047-13051
Rees NV, Klymenko OV, Coles BA, Compton RG (2003)Hydrodynamics and mass transport in wall-tube and microjet electrodes: An experimental evaluation of current theory, In: Journal of Physical Chemistry B107(49)pp. 13649-13660
Buzzeo MC, Klymenko OV, Wadhawan JD, Hardacre C, Seddon KR, Compton RG (2003)Voltammetry of oxygen in the room-temperature ionic liquids 1-ethyl-3-methylimidazolium bis((trifluoromethyl)sulfonyl)imide and hexyltriethylammonium bis((trifluoromethyl)sulfonyl)imide: One-electron reduction to form superoxide. Steady-state and transient behavior in the same cyclic voltammogram resulting from widely different diffusion coefficients of oxygen and superoxide, In: Journal of Physical Chemistry A107(42)pp. 8872-8878
Wain AJ, Thompson M, Klymenko OV, Compton RG (2004)An improved configuration for simultaneous electrochemical ESR studies: A tubular electrode in a cylindrical cavity, In: Physical Chemistry Chemical Physics6(15)pp. 4018-4027
Thompson M, Klymenko OV, Compton RG (2005)Mass transport limited currents at the tubular electrode, In: Journal of Electroanalytical Chemistry575(2)pp. 329-337
Clegg AD, Rees NV, Klymenko OV, Coles BA, Compton RG (2004)Marcus theory of outer-sphere heterogeneous electron transfer reactions: dependence of the standard electrochemical rate constant on the hydrodynamic radius from high precision measurements of the oxidation of anthracene and its derivatives in nonaqueous solvents using the high-speed channel electrode., In: J Am Chem Soc126(19)pp. 6185-6192
Buzzeo MC, Klymenko OV, Wadhawan JD, Hardacre C, Seddon KR, Compton RG (2004)Kinetic Analysis of the Reaction between Electrogenerated Superoxide and Carbon Dioxide in the Room Temperature Ionic Liquids 1-Ethyl-3-methylimidazolium Bis(trifluoromethylsulfonyl)imide and Hexyltriethylammonium Bis(trifluoromethylsulfonyl)imide, In: Journal of Physical Chemistry B108(12)pp. 3947-3954
Klymenko OV, Shah N, Kontoravdi C, Royle KE, Polizzi KM (2016)Designing an Artificial Golgi Reactor to Achieve Targeted Glycosylation of Monoclonal Antibodies, In: AICHE JOURNAL62(9)pp. 2959-2973 WILEY-BLACKWELL
Evans RG, Klymenko OV, Saddoughi SA, Hardacre C, Compton RG (2004)Electroreduction of oxygen in a series of room temperature ionic liquids composed of group 15-centered cations and anions, In: JOURNAL OF PHYSICAL CHEMISTRY B108(23)pp. 7878-7886 AMER CHEMICAL SOC
Klymenko OV, Amatore C, Svir I, Oleinick A (2015)Strong and Unexpected Effects of Diffusion Rates on the Generation of Electrochemiluminescence by Amine/Transition-Metal(II) Systems, In: ChemElectroChem2(6)pp. 811-818
Klymenko OV, Svir I, Amatore C (2013)A new approach for the simulation of electrochemiluminescence (ECL)., In: Chemphyschem14(10)pp. 2237-2250
Muir Luke, McKay Paul F., Petrova Velislava N., Klymenko Oleksiy V., Kratochvil Sven, Pinder Christopher L., Kellam Paul, Shattock Robin J. (2018)Optimisation of ex vivo memory B cell expansion/differentiation for interrogation of rare peripheral memory B cell subset responses, In: Wellcome Open Research297pp. 1-25 F1000Research
Forryan CL, Klymenko OV, Brennan CM, Compton RG (2005)Reactions at the solid-liquid interface: surface-controlled dissolution of solid particles. The dissolution of potassium bicarbonate in dimethylformamide., In: J Phys Chem B109(7)pp. 2862-2872
Tippmann EM, Platz MS, Svir IB, Klymenko OV (2004)Evidence for specific solvation of two halocarbene amides., In: J Am Chem Soc126(18)pp. 5750-5762
Oleinick A, Klymenko Oleksiy, Svir I, Amatore C (2017)Theoretical Insights in ECL, In: Miomandre F, Audebert P (eds.), Luminescence in Electrochemistrypp. 215-256 Springer International Publishing
Forryan CL, Klymenko OV, Wilkins SJ, Brennan CM, Compton RG (2005)Experimental and theoretical study of the surface-controlled dissolution of cylindrical particles. Application to solubilization of potassium hydrogen carbonate in hot dimethylformamide., In: J Phys Chem B109(44)pp. 20786-20793
Forryan CL, Compton RG, Klymenko OV, Brennan CM, Taylor CL, Lennon M (2006)Comparative solubilisation of potassium carbonate, sodium bicarbonate and sodium carbonate in hot dimethylformamide: application of cylindrical particle surface-controlled dissolution theory., In: Phys Chem Chem Phys8(5)pp. 633-641
Oleinick AI, Amatore C, Guille M, Arbault S, Klymenko OV, Svir I (2006)Modelling release of nitric oxide in a slice of rat’s brain: describing stimulated functional hyperemia with diffusion-reaction equations., In: Math Med Biol23(1)pp. 27-44
Amatore C, Klymenko OV, Svir I (2006)In situ and online monitoring of hydrodynamic flow profiles in microfluidic channels based upon microelectrochemistry: optimization of electrode locations., In: Chemphyschem7(2)pp. 482-487
Chevallier FG, Davies TJ, Klymenko OV, Jiang L, Jones TGJ, Compton RG (2005)Influence of the block geometry on the voltammetric response of partially blocked electrodes: Application to interfacial liquid-liquid kinetics of aqueous vitamin B12S with random arrays of femtolitre microdroplets of dibromocyclohexane, In: Journal of Electroanalytical Chemistry580(2)pp. 265-274
Clegg AD, Rees NV, Klymenko OV, Coles BA, Compton RG (2005)Marcus theory of outer-sphere heterogeneous electron transfer reactions: High precision steady-state measurements of the standard electrochemical rate constant for ferrocene derivatives in alkyl cyanide solvents, In: Journal of Electroanalytical Chemistry580(1)pp. 78-86
Forryan CL, Klymenko OV, Brennan CM, Compton RG (2005)Heterogeneous kinetics of the dissolution of an inorganic salt, potassium carbonate, in an organic solvent, dimethylformamide., In: J Phys Chem B109(16)pp. 8263-8269
Chevallier FG, Davies TJ, Klymenko OV, Jiang L, Jones TGJ, Compton RG (2005)Numerical simulation of partially blocked electrodes under cyclic voltammetry conditions: Influence of the block unit geometry on the global electrochemical properties, In: Journal of Electroanalytical Chemistry577(2)pp. 211-221
Klymenko OV, Giovanelli D, Lawrence NS, Rees NV, Jiang L, Jones TGJ, Compton RG (2003)The electrochemical oxidation of N,N-diethyl-p-phenylenediamine in DMF and analytical applications. Part I: Mechanistic study, In: Electroanalysis15(11)pp. 949-960
Rees NV, Klymenko OV, Coles BA, Compton RG (2003)Fast scan linear sweep voltammetry at a high-speed wall-tube electrode, In: Journal of Electroanalytical Chemistry557pp. 99-107
Kotidis Pavlos, Demis Panagiotis, Goey Cher H., Correa Elisa, McIntosh Calum, Trepekli Stefania, Shah Nilay, Klymenko Oleksiy V., Kontoravdi Cleo (2019)Constrained global sensitivity analysis for bioprocess design space identification, In: Computers and Chemical Engineering125pp. 558-568 Elsevier
Casula Elisa, Traversari Gabriele, Fadda S, Klymenko Oleksiy V., Kontoravdi Cleo, Cincotti Alberto (2019)Modelling the osmotic behaviour of human mesenchymal stem cells, In: Biochemical Engineering Journal151107296 Elsevier
Klymenko Oleksiy V., Kucherenko Sergei, Shah Nilay Constrained Global Sensitivity Analysis: Sobol’ indices for problems in non-rectangular domains, In: 27th European Symposium on Computer Aided Process Engineering40pp. 151-156 Elsevier
Thompson M, Klymenko OV, Compton RG (2005)Modelling homogeneous kinetics in the double channel electrode, In: Journal of Electroanalytical Chemistry576(2)pp. 333-338
Klymenko OV, Buriez O, Labbé E, Zhan D-P, Rondinini S, Tian Z-Q, Svir I, Amatore C (2014)Uncovering the Missing Link between Molecular Electrochemistry and Electrocatalysis: Mechanism of the Reduction of Benzyl Chloride at Silver Cathodes, In: ChemElectroChem1(1)pp. 227-240
Klymenko OV, Svir I, Amatore C (2014)Molecular electrochemistry and electrocatalysis: A dynamic view, In: Molecular Physics112(9-10)pp. 1273-1283
Evans RG, Klymenko OV, Hardacre C, Seddon KR, Compton RG (2003)Oxidation of N,N,N ’,N ’-tetraalkyl-para-phenylenediamines in a series of room temperature ionic liquids incorporating the bis(trifluoromethylsulfonyl)imide anion, In: JOURNAL OF ELECTROANALYTICAL CHEMISTRY556pp. 179-188 ELSEVIER SCIENCE SA
Amatore C, Oleinick A, Klymenko OV, Svir I (2005)In situ and online monitoring of hydrodynamic flow profiles in microfluidic channels based upon microelectrochemistry: concept, theory, and validation., In: Chemphyschem6(8)pp. 1581-1589
Evans RG, Klymenko OV, Price PD, Davies SG, Hardacre C, Compton RG (2005)A comparative electrochemical study of diffusion in room temperature ionic liquid solvents versus acetonitrile, In: CHEMPHYSCHEM6(3)pp. 526-533 WILEY-V C H VERLAG GMBH