Deborah Dunn Walters

Professor Deborah Dunn-Walters FRSB


Professor of Immunology, Lead for University Research Theme Lifelong Health
BSc (Hons I), PhD
Flexible, Zoom/Teams by appointment. Drop me an email to arrange

Biography

University roles and responsibilities

  • Section Lead Immunology
  • Lead for University Research Theme Lifelong Health

    Previous roles

    2017 - 2019
    School of Biosciences and Medicine Research Director

    Affiliations and memberships

    FRSB
    Fellow of the Royal Society of Biology
    BSI
    Member of the British Society for Immunology
    BSRA
    Member of the British Society for Research on Ageing

    Research

    Research interests

    My publications

    Publications

    Liu Hongxiang, Goodlad John, Ashton-Key Margaret, Raderer Markus, Bi Yingwen, Du Ming-Qing, Moody Sarah, Escudero-Ibarz Leire, Wang Ming, Xue Xuemin, Clipson Alexandra, Ochoa Ruiz Eguzkine, Dunn-Walters Deborah, Zeng Naiyan, Robson Alistair, Cogliatti Sergio, Chuang Shih-Sung (2017)Significant association between TNFAIP3 inactivation and biased IGHV4-34 usage in MALT lymphoma, In: Journal of Pathology243(1)pp. 3-8 Wiley
    Martin VG, Wu Y-CB, Townsend CL, Lu GH, O'Hare JS, Mozeika A, Coolen AC, Kipling D, Fraternali F, Dunn-Walters Deborah (2016)Transitional B cells in early human B cell development - time to revisit the paradigm?, In: Frontiers in Immunology7546 Frontiers Media
    Michaeli M, Tabibian-Keissar H, Schiby G, Shahaf G, Pickman Y, Hazanov L, Rosenblatt K, Dunn-Walters D, Barshack I, Mehr R (2014)Immunoglobulin gene repertoire diversification and selection in the stomach – from gastritis to gastric lymphomas, In: Frontiers in Immunology5264pp. 1-14 Frontiers Media
    Fraser LD, Zhao Y, Lutalo PMK, D’Cruz DP, Cason J, Silva JS, Dunn-Walters D, Nayar S, Cope AP, Spencer J (2016)Immunoglobulin light chain allelic inclusion in systemic lupus erythematosus, In: European Journal of Immunology45(8)pp. 2409-2419 Wiley
    Sabouria Z, Schofield P, Horikawa K, Spierings E, Kipling D, Randall KL, Langley D, Roome B, Vazquez-Lombardi R, Rouet R, Hermes J, Chan TD, Brink R, Dunn-Walters D, Christ D, Goodnow CC (2014)Redemption of autoantibodies on anergic B cells by variable-region glycosylation and mutation away from self-reactivity, In: PNAS111(25)pp. E2567-E2575 National Academy of Sciences
    Martin V, Wu Y-C, Kipling D, Dunn-Walters D (2015)Ageing of the B-cell repertoire, In: Philosophical Transactions of the Royal Society B370(1676) The Royal Society Publishing
    Wu Y-C, Kipling D, Dunn-Walters D (2015)Assessment of B cell repertoire in humans, In: Methods in Molecular Biology1343pp. 199-218 Humana Press
    Martin V, Wu Y-C, Kipling D, Dunn-Walters D (2015)Age-related aspects of human IgM+ B cell heterogeneity, In: Annals of the New York Academy of Sciences1362(B-1 Ce)pp. 153-163 Wiley
    Sáez de Guinoa Julia, Jimeno Rebeca, Gaya Mauro, Kipling David, Garzón María José, Dunn-Walters Deborah, Ubeda Carles, Barral Patricia (2018)CD1d-mediated lipid presentation by CD11c+ cells regulates intestinal homeostasis, In: The EMBO Journal37(5)e97537pp. 1-17 EMBO Press
    Kipling David, Dunn-Walters Deborah, Pan-Hammarström Qiang, Björkman Andrea, Du Likun, van der Burg Mirjam, Cormier-Daire Valerie, Borck Guntram, Pié Juan, Anderlid Britt-Marie, Hammarström Lennart, Ström Lena, de Villartay Jean-Pierre (2017)Reduced immunoglobulin gene diversity in patients with Cornelia de Lange syndrome, In: Journal of Allergy and Clinical Immunology141(1)pp. 408-411.e8 Elsevier
    Dunn-Walters Deborah, Stewart Alexander, Sinclair Emma, Serangeli Ilaria (2019)Age-related changes in B cells relevant to vaccine responses, In: Interdisciplinary Topics in Gerontology and Geriatrics S. Karger AG, Basel
    Margreitter Christian, Lu Hui-Chun, Townsend Catherine, Stewart Alexander, Dunn-Walters Deborah, Fraternali Franca (2018)BRepertoire: A user-friendly web server for analysing antibody repertoire data, In: Nucleic Acids Research46(W1)pp. W264-W270 Oxford University Press (OUP)
    Dunn-Walters Deborah, Townsend C, Sinclair Emma, Stewart Alexander (2018)Immunoglobulin gene analysis as a tool for investigating human immune responses, In: Immunological Reviews284(1)pp. 132-147 Wiley
    Laffy JMJ, Dodev T, Macpherson JA, Townsend C, Lu HC, Dunn-Walters Deborah, Fraternali F (2016)Promiscuous antibodies characterised by their physico-chemical properties: From sequence to structure and back, In: Progress in Biophysics and Molecular Biology128pp. 47-56 Elsevier
    Dunn-Walters D (2015)The ageing human B cell repertoire: A failure of selection?, In: Clinical & Experimental Immunology183(1)pp. 50-56 Wiley
    Crawford Greg, Hayes Mark David, Seoane Rocio Castro, Ward Sophie, Dalessandri Tim, Lai Chester, Healy Eugene, Kipling David, Proby Charlotte, Moyes Colin, Green Kile, Best Katie, Haniffa Muzlifah, Botto Marina, Dunn-Walters Deborah, Strid Jessica (2018)Epithelial damage and tissue γδ T cells promote a unique tumor-protective IgE response, In: Nature Immunology19pp. 859-870 Nature Publishing Group
    Tabibian-Keissar∗ H, Hazanov L, Schiby G, Rosenthal N, Rakovsky A, Rosenblatt K, Michaeli M, Shahaf GL, Pickman Y, Melamed D, Dunn-Walters D, Mehr R, Barshack I (2015)Aging affects B-cell antigen receptor repertoire diversity in primary and secondary lymphoid tissues, In: European Journal of Immunology46(2)pp. 480-492 2015 WILEY-VCH Verlag GmbH & Co
    Da Silva L, Weller S, Dunn-Walters D, Weill J-C, Reynaud C-A, Bagnara D, Squillario M, Kipling D, Mora T, Walczak AM (2015)A reassessment of IgM memory subsets in humans, In: Journal of Immunology195(8)pp. 3716-3724 American Association of Immunologists
    Pawelec Graham, Müller Ludmila, Fülöp Tamas, Dunn-Walters Deborah (2017)Immune system changes and immunosenescence, In: Michel Jean-Pierre, Beattie B. Lynn, Martin Finbarr C., Walston Jeremy D. (eds.), Oxford Textbook of Geriatric Medicine Oxford University Press
    Townsend CL, Laffy JMJ, Wu Y-C, O’Hare JS, Martin V, Kipling D, Fraternali F, Dunn-Walters Deborah (2016)Significant differences in physicochemical properties of human immunoglobulin kappa and lambda CDR3 regions, In: Frontiers in Immunology216 Frontiers Media
    Dunn-Walters Deborah, O’Hare Joselli Silva (2017)Older Human B Cells and Antibodies, In: Fulop Tamas, Franceschi Claudio, Hirokawa Katsuiku, Pawelec Graham (eds.), Handbook of Immunosenescencepp. 1-34 Springer International Publishing