Dr Denise Marston


Teaching Fellow (Veterinary Virology)
PhD
I work Monday-Friday for 3-4 hrs each day between 9am and 4pm

Biography

Areas of specialism

Veterinary Virology; Virus evolution

My qualifications

2017
PhD (Infectious Diseases)
AIX Marseille University
1997
BSc (Hons) Biological Science (Microbiology)
University of Leicester

In the media

My publications

Publications

Arran J. Folly, Denise A. Marston, Megan Golding, Shweta Shukla, Rebekah Wilkie, Fabian Z. X. Lean, Alejandro Núñez, Lisa Worledge, James Aegerter, Ashley C. Banyard, Anthony R. Fooks, Nicholas Johnson, Lorraine M. McElhinney (2021)Incursion of European Bat Lyssavirus 1 (EBLV-1) in Serotine Bats in the United Kingdom, In: Viruses13(10)1979 MDPI

Lyssaviruses are an important genus of zoonotic viruses which cause the disease rabies. The United Kingdom is free of classical rabies (RABV). However, bat rabies due to European bat lyssavirus 2 (EBLV-2), has been detected in Daubenton’s bats (Myotis daubentonii) in Great Britain since 1996, including a fatal human case in Scotland in 2002. Across Europe, European bat lyssavirus 1 (EBLV-1) is commonly associated with serotine bats (Eptesicus serotinus). Despite the presence of serotine bats across large parts of southern England, EBLV-1 had not previously been detected in this population. However, in 2018, EBLV-1 was detected through passive surveillance in a serotine bat from Dorset, England, using a combination of fluorescent antibody test, reverse transcription-PCR, Sanger sequencing and immunohistochemical analysis. Subsequent EBLV-1 positive serotine bats have been identified in South West England, again through passive surveillance, during 2018, 2019 and 2020. Here, we confirm details of seven cases of EBLV-1 and present similarities in genetic sequence indicating that emergence of EBLV-1 is likely to be recent, potentially associated with the natural movement of bats from the near continent