Ines is a Lecturer in Psychological Neuroscience in the School of Psychology, FHMS.
She received BSc in Biochemistry and PhD in Biomedical Sciences from the University of Coimbra, Portugal.
Following her PhD, Ines was awarded a Sir Henry Wellcome Fellowship to perform her research project at Imperial College London and University College London.
Areas of specialism
University roles and responsibilities
- Year 2 Tutor (BSc Psychology Programme)
- CUBIC Management Committee
- Research Committee
My research focuses on understanding the role of brain networks on cognitive functions and the use of brain stimulation as a neuromodulator. My research combines functional magnetic resonance imaging (fMRI) and electroencephalography (EEG) to understand how brain stimulation (TMS, tACS, tDCS) can be used to modulate brain dynamics and behavioural performance. I am interested in how brain oscillations mediate long-range connectivity and particularly how neurostimulation can be used to improve network communication following neurological disorders.
A second strand of research that started during my PhD, has been focused on understanding the neurobiological basis of the cognitive deficits in neurodevelopmental disorders, particularly Neurofibromatosis type 1 (NF1). My research in this field is characterized by being interdisciplinary and translational, applying neuroimaging and neurophysiological techniques to translate the inhibitory hypothesis in NF1. I have used spectroscopy (MRS), molecular imaging (PET) and magnetic resonance imaging to provide a comprehensive understanding of the pathophysiological alterations present in NF1.
Prof. Robert Leech, King's College London
Dr. Adam Hampshire, Imperial College London
Dr. Nir Grossman, Imperial College London
Prof. David Sharp, Imperial College London
Prof. John Rothwell, University College London
Dr. David Carmichael, King's College London
Dr. Miguel Castelo-Branco, University of Coimbra
Indicators of esteem
2019 - 2021: Dynamic modulation of brain states using brain stimulation and neuroadaptive Bayesian optimization. BBSRC (PI)
2018 - 2019: Developing a measure of conscious level with electroencephalography and transcranial electrical stimulation. Imperial Confidence in Concept (Co-PI)
2016 - 2017: Tailored non-invasive brain stimulation for rehabilitation of TBI using real-time time fMRI. NIHR Imperial Biomedical Research Centre (PI)
2014 - 2018: Stimulating brain network oscillations to improve attention after traumatic brain injury. Wellcome Trust (Sir Henry Wellcome Postdoctoral Fellow)
Honours, Awards and Fellowships
2013 Sir Henry Wellcome Postdoctoral Fellowship
2014 Finalist Young Investigator Award, World Molecular Imaging Conference, Seoul, South Korea
2013 Best Scientific Article - Clinical Research, Faculty of Medicine, University of Coimbra
2012 Certificate of Merit Award, ESMRMB 29th Annuak Scientific Meeting
2012 Trainee Abstract Travel Award, Organization for Human Brain Mapping
2011 Best Scientific Poster, 3rd Annual Meeting, IBILI, Portugal
2009 International Society for Magnetic Resonance in Medicine and Biology Travel Award
2008 International Society for Magnetic Resonance in Medicine and Biology Travel Award
2008 European Society for Magnetic Resonance in Medicine and Biology Travel Award
2008 PhD Fellowship, Portuguese Foundation for Science and Technology
2006 Erasmus Student Fellowship
Postgraduate research supervision
Postgraduate research supervision
If you are a student who is interested in undertaking PhD or postdoctoral research in my lab then please feel free to email me directly at ines.violante_at_surrey.ac.uk.
Danielle Kurtin (PhD Candidate)
Henry Hebron (PhD Candidate)
Will Mayes (PhD Candidate) - Multi-sensory integration in Developmental Coordination Dirorder
Paul Knytl (PhD Candidate) - Dopamine & Meditation
Biological Psychology with Research Methods (Year 1)
Brain and Behaviour with Research Methods (MSc Conversion)
Ekhtiari, H., Ghobadi-Azbari, P., Thielscher, A. et al. A checklist for assessing the methodological quality of concurrent tES-fMRI studies (ContES checklist): a consensus study and statement. Nature Protocols (2022), 17, 596–617.
Bernardino I, Dionisio A, Violante IR, Monteiro R, Castelo-Branco M. Motor cortex excitation/inhibition imbalance in young adults with autism spectrum disorder: a multimodal approach. Frontiers in Psychiatry (2022)
Mayes W, Gentle J, Parisi I, Dixon L, van Velzen J, Violante IR. Top-down inhibitory motor control is preserved in adults with Developmental Coordination Disorder. Developmental Neuropsychology (2021), https://doi.org/10.1080/87565641.2021.1966431
Kurtin DL, Violante IR, Zimmerman K, Leech R, Hampshire A, Patel MC, Carmichael DW, Sharp DJ, Li LM. Investigating the interaction between white matter and brain state on tDCS-induced changes in brain network activity. Brain Stimulation (2021), 14:5, 1261-1270
Soreq E, Violante IR, Daws R, Hampshire A. Neuroimaging evidence for a network sampling theory of individual differences in human intelligence test performance. Nature Communications (2021), DOI: 10.1038/s41467-021-22199-9
Parkin B, Daws RE, Das Neves I, Violante IR, Soreq E, Martin-Bastida A, Sandrone S, Roussakis AA, Lao-Kaim NP, Piccini P, Hampshire A. Dissociable Effects of Age and Parkinson’s Disease on Instruction Based Learning. Brain Communications (2021)
Beppi C, Violante IR, Scott G, Sandrone S. EEG, MEG and neuromodulatory approaches to explore cognition: Current status and future directions. Brain and Cognition (2021) 148, 105677
Ekhtiari H, et al. A Checklist for Assessing the Methodological Quality of Concurrent tES-fMRI Studies (ContES Checklist): A Consensus Study and Statement. medRxiv 2020.12.23.20248579; doi: https://doi.org/10.1101/2020.12.23.20248579
Goldthorpe RA, Rapley JM, Violante IR. A Systematic Review of Non-invasive Brain Stimulation Applications to Memory in Healthy Aging. Front. Neurol., (2020)
Cogdell-Brooke, L., Sowden, P., Violante, IR., and Thompson, HE. A meta-analysis of functional magnetic resonance imaging studies of divergent thinking using activation likelihood estimation. Human Brain Mapping (2020) 1:21
Cogdell-Brooke L, Stampacchia S, Jefferies E, Violante IR, Thompson HE. Consistently inconsistent: Multimodal episodic deficits in semantic aphasia. Neuropsychologia (2020)
Fagerholm ED, Tangwiriyasakul C, Friston KJ, Violante IR, Williams S, Carmichael DW, Perani S, Turkheimer FE, Moran RJ, Leech R, Richardson MP. Neural diffusivity and pre-emptive epileptic seizure intervention. PLOS Computational Biology (2020)
Fagerholm, ED, Moran, RJ, Violante, IR, Leech R, Friston KJ. Dynamic causal modelling of phase-amplitude interactions. NeuroImage (2020) 208: 116452
Arana-Oiarbide G, Daws RE, Lorenz R, Violante IR, Hampshire A. Preferential activation of the posterior Default-Mode Network with sequentially predictable task switches. bioRxiv
Beppi C, Violante IR, Hampshire A, Grossman N, Sandrone S. Patterns of Focal-and Large-Scale Synchronization in Cognitive Control and Inhibition: A Review. Frontiers in Human Neuroscience (2020) 14: 196
d’Almeida OC, Violante IR, Quendera B, Moreno C, Gomes L, Castelo-Branco M. The neurometabolic profiles of GABA and Glutamate as revealed by proton magnetic resonance spectroscopy in type 1 and type 2 diabetes. PLoS ONE (2020), 15(10): e0240907.
Li LM, Violante IR, Zimmerman K, Leech R, Hampshire A, Patel M, Opitz A, McArthur D, Jolly A, Carmichael DW, Sharp DJ. Traumatic axonal injury influences the cognitive effect of non-invasive brain stimulation. Brain (2019) 142:3280-3293
Lorenz R, Simmons LE, Monti RP, Arthur JL, Limal S, Laakso I, Leech R, Violante IR. Efficiently searching through large tACS parameter spaces using closed-loop Bayesian optimization. Brain Stimulation (2019) 12:1484-1489
Hampshire A, Daws RE, Neves ID, Soreq E, Sandrone S, Violante IR. Probing cortical and sub-cortical contributions to instruction-based learning: Regional specialisation and global network dynamics. NeuroImage (2019) 192:88-100
Li LM, Violante IR, Leech R, Hampshire A, Opitz A, McArthur D, Carmichael DW, Sharp DJ. Cognitive enhancement with Salience Network electrical stimulation is influenced by network structural connectivity. NeuroImage (2019) 185:425-433
Li LM, Violante IR, Leech R, Ross E, Hampshire A, Opitz A, Rothwell JC, Carmichael DW, Sharp DJ. Brain state and polarity dependent modulation of brain networks by transcranial direct current stimulation. Hum Brain Mapp. (2019) 40(3):904-915
Lorenz R, Violante IR, Monti RP, Montana G, Hampshire A, Leech R. Dissociating frontoparietal brain networks with neuroadaptive Bayesian optimization. Nature Communications (2018) 26;9(1):1227. doi: 10.1038/s41467-018-03657-3.
Silva G, Duarte IC, Bernardino I, Marques T, Violante IR, Castelo-Branco M. Oscillatory motor patterning is impaired in neurofibromatosis type 1: a behavioural, EEG and fMRI study. J Neurodev Disord. (2018) 22;10(1):11. doi: 10.1186/s11689-018-9230-4.
Carvalho Pereira A, Violante IR, Mouga S, Oliveira G, Castelo-Branco M. Medial Frontal Lobe Neurochemistry in Autism Spectrum Disorder is Marked by Reduced N-Acetylaspartate and Unchanged Gamma-Aminobutyric Acid and Glutamate + Glutamine Levels. J Autism Dev Disord. (2018) 48(5):1467-1482. doi: 10.1007/s10803-017-3406-8.
d’Almeida OC, Violante IR, Quendera B, Castelo-Branco M. Mitochondrial pathophysiology beyond the retinal ganglion cell: occipital GABA is decreased in autosomal dominant optic neuropathy. Graefe's Archive for Clinical and Experimental Ophthalmology (2018) 256(12),2341-2348.
Violante IR, Li LM, Carmichael DW, Lorenz R, Leech R, Hampshire A, Rothwell JC, Sharp DJ. Externally induced frontoparietal synchronization modulates network dynamics and enhances working memory performance. eLife (2017), Mar 14;6. pii: e22001. doi: 10.7554/eLife.22001.
Sliwinska M, Violante IR, Wise R, Leech R, Devlin J, Geranmayeh F, Hampshire A. Stimulating domain-general neural networks improves vocabulary learning. Journal of Neuroscience (2017), 3857-16; DOI: https://doi.org/10.1523/JNEUROSCI.3857-16.2017
Gonçalves J, Violante IR, Sereno J, Leitão R, Cai Y, Abrunhosa A, Silva AP, Silva A, Castelo- Branco M. Testing the excitation/inhibition imbalance hypothesis in a mouse model of the autism spectrum disorder: in vivo neurospectroscopy and molecular evidence for regional phenotypes. Mol Autism. (2017) Sep 19;8:47. doi: 10.1186/s13229-017-0166-4. eCollection 2017.
Datta G, Violante IR, Scott G, Zimmerman K, Santos-Ribeiro A, Rabiner EA, Gunn RN, Malik O, Ciccarelli O, Nicholas R, Matthews PM. Translocator positron-emission tomography and magnetic resonance spectroscopic imaging of brain glial cell activation in multiple sclerosis. Multiple Sclerosis Journal (2017) 23(11):1469-1478.
Violante IR, Ribeiro MJ, Patricio M, Bernardino I, Rebola J, Abrunhosa AJ, Ferreira N, Castelo-Branco M. GABA deficiency in NF1: a multimodal [11C]-Flumazenil and spectroscopy study. Neurology (2016) 87(9):897-904
Silva G, Ribeiro MJ, Costa GN, Violante IR, Ramos F, Saraiva J, Castelo-Branco M. Peripheral Attentional Targets under Covert Attention Lead to Paradoxically Enhanced Alpha Desynchronization in Neurofibromatosis Type 1. PLoS One (2016) 11(2):e0148600. doi: 10.1371/journal.pone.0148600.
Lorenz R, Monti RP, Violante IR, Anagnostopoulos C, Faisal AA, Montana G, Leech R. The Automatic Neuroscientist: A framework for optimizing experimental design with closed-loop real-time fMRI. Neuroimage (2016) 129:320-34.
Ribeiro MJ, Violante IR, Bernardino I, Edden RAE, Castelo-Branco M. Abnormal relationship between GABA, neurophysiology and impulsive behavior in neurofibromatosis type 1. Cortex (2015) 64:194-208.
Violante IR, Ribeiro MJ, Edden RAE, Guimarães P, Bernardino I, Rebola J, Cunha G, Silva E, Castelo-Branco M. GABA deficit in the visual cortex of patients with NF1: genotype-phenotype correlations and functional impact. Brain 136:3 (2013) 918-25.
Violante IR, Ribeiro MJ, Silva E, Castelo-Branco M. Gyrification, cortical and subcortical morphometry in Neurofibromatosis type 1: an uneven profile of developmental abnormalities. Journal of Neurodevelopmental Disorders 5:3 (2013) doi: 10.1186/1866-1955-5-3.
Violante IR, Ribeiro MJ, Cunha G, Bernardino I, Duarte JV, Ramos F, Saraiva J, Silva E, Castelo-Branco M. Abnormal brain activation in neurofibromatosis type 1: a link between visual processing and the default mode network. PLoS One. 7:6 (2012) e38785.
Duarte JV, Ribeiro MJ, Violante IR, Cunha G, Silva E, Castelo-Branco M. Multivariate Pattern Analysis Reveals Subtle Brain Anomalies Relevant to the Cognitive Phenotype in Neurofibromatosis Type 1. Human Brain Mapping (2012) doi: 10.1002/hbm.22161
Ribeiro MJ, Violante IR, Bernardino I, Ramos F, Saraiva J, Reviriego P, Upadhyaya M, Silva ED, Castelo-Branco M. Abnormal achromatic and chromatic contrast sensitivity in neurofibromatosis type 1. Invest Ophthalmol Vis Sci. 53:1 (2012) 287-293.
2007 - 2011
Delgado TC, Violante IR, Nieto-Charques L, Cerdan S. Neuroglial metabolic compartmentation underlying leptin deficiency in the obese ob/ob mice as detected by magnetic resonance imaging and spectroscopy methods. J Cereb Blood Flow Metab. 31:12 (2011) 2257-2266.
Rodrigues TB, Violante IR, Cerdan S. Unambiguous assignment of the H3S and H3R deuterations of cerebral (2-13C) glutamate by 13C NMR at 18.8 Tesla. Magn Reson Med. 63:4 (2010) 1088-1091.
Violante IR, Anastasovska J, Sanchez-Canon GJ, Rodrigues TB, Righi V, Nieto-Charques L, Parkinson JR, Bloom SR, Bell JD, Cerdan S. Cerebral activation by fasting induces lactate accumulation in the hypothalamus. Magn Reson Med. 62:2 (2009) 279-283.
Ramirez BG, Rodrigues TB, Violante IR, Cruz F, Fonseca LL, Ballesteros P, Castro MM, Garcia-Martin ML, Cerdan S. Kinetic properties of the redox switch/redox coupling mechanism as determined in primary cultures of cortical neurons and astrocytes from rat brain. J Neurosci Res. 85:15 (2007) 3244-3253.
Lorenz R, Monti RP, Hampshire A, Koush Y, Anagnostopoulos C, Faisal A, Sharp D, Montana G, Leech R, Violante IR. Towards tailoring non-invasive brain stimulation using real-time fMRI and Bayesian optimization. (2016) 6th International Workshop on Pattern Recognition in Neuroimaging (PRNI) - Best Paper Award
Lorenz R, Monti RP, Violante IR, Faisal A, Anagnostopoulos C, Leech R, Montana G. Stopping criteria for boosting automatic experimental design using real-time fMRI with Bayesian optimization. (2015) 5th NIPS Workshop on Machine Learning and Interpretation in Neuroimaging: Beyond the Scanner