Dr Jonathan Brown

Papers

Al-Mssallem, M., Frost G., Hampton S. and Brown J.E. (2010) A study of Hassawi rice (Oryza sativa L.) in terms of its carbohydrate hydrolysis in vitro and glycaemic and insulinaemic indices in vivo. (submitted to EJCN)

Rizzo, V., Clifford, M.N. and Brown, J.E. (2010) The effects of processing on polyphenol and phenolic acid content and antioxidant activity of semi-dried cherry tomatoes (Lycopersicon esculentum M.) (in preparation)

Jamil, D.M., Howell, N.K. and Brown, J.E. (2010) Protection of low density lipoprotein from copper-mediated oxidation by the volatile oils of Thymus Syriacus Boiss. var syriacus and Thymbra spicata L. and their primary constituents (in preparation)

Jamil, D.M., Brown, J.E., Driscoll, D. and Howell, N.K. (2010) Characterization of the volatile oil content and composition of Thymus Syriacus Boiss. var syriacus and Thymbra spicata L. by gas chromatography (GC) and GC-mass spectrometry (in preparation)

Stoupi, S., Williamson, G., Viton F., Barron D., King, L.J. Brown, J.E. and Clifford M.N. (2010) In vivo bioavailability, absorption, excretion and pharmacokinetics of [14C] procyanidin in male rats. Drug Metabolism and Disposition, 38(2), 287-291

Brown, J.E. and Kelly M.F. (2008) Influence of dietary cholesterol and stress on the metabolism of linoleic acid: Δ6-desaturase activity vs. product precursor ratios. International Journal of Food Safety, Nutrition and Public Health 1: 5-15

Gannon, R.H.T., Millward D.J., Brown J.E., MacDonald H.M., Lovell D.P., Frasetto L.A., Remer T. and Lanham-New S.A. (2008) Estimates of net acid excretion (NAEind) and net rate of endogenous non-carbonic acid production (NEAP) in the elderly UK population: analysis of the National Diet and Nutrition Survey (NDNS) of British adults aged 65 years and over. British Journal of Nutrition 100:615-623

Rahimuddin, S.A., Khoja, S.M., Zuhair, M.M., Howell N.K. and Brown, J.E. (2007) Inhibition of lipid peroxidation in UVA-treated skin fibroblasts by luteolin and its glucosides. European Journal of Lipid Science Technology 109 (7): 647-655

Brown, J.E. and Kelly M.F. (2007) Inhibition of lipid peroxidation by anthocyanins, anthocyanidins and phenolic degradation products. European Journal of Lipid Science Technology 109 (1):66-71

Cassidy A., Brown J.E., Hawdon, A., Faughnan M.S., King L.J., Millward J., Zimmer-Nechemias L., Wolfe B. and Setchell K.D.R. (2006) Factors affecting the bioavailability of soy isoflavones in humans after ingestion of physiologically relevant levels from different soy foods. Journal of Nutrition 136:45-51

Clifford, M.N. and Brown J.E. (2006) Dietary flavonoids and health - broadening the perspective in - Flavonoids: Chemistry, Biochemistry and Application, Edited by Andersen and Markham CRC Press. pp 320-370

Harmer J. and Brown J.E. (2005) Properties of cyanidin-3-glucoside and malvidin-3-glucoside in relation to their ability to prevent low density lipoprotein oxidation at physiological concentrations. Nutrition and Health Current Topics IV, Edited by T. Carr and K. Descheemaeker, Garant Publishers pp. 167-168

Brown J.E. (2005) A critical review of methods used to estimate linoleic acid Δ6-desaturation ex vivo and in vivo. European Journal of Lipid Science Technology 107 (2):119-134

Faughnan M.S., Hawdon A., Ah-Singh E., Brown J.E., Millward D.J. and Cassidy A. (2004) Urinary isoflavone kinetics: the effect of age, gender, food matrix and chemical composition. British Journal of Nutrition 91 (4): 567-574

Au A., and Brown J.E. (2002) The role of glycosylation on the antioxidant properties of polyphenols. Free Radical Biology and Medicine 33 (S1) S198

Tyrrell R.M., Pourzand C.A., Brown J.E., Hejmadi V., Kvam E., Ryter S. and Watkin R.D. (2000) Cellular studies with UVA radiation: A role for iron. Radiation Protection Dosimetry 91 (1-3): 37-39

Brown J.E., Lindsay, R.M. and Riemersma, R.A.(2000) Linoleic acid metabolism in the spontaneously diabetic rat. Δ6-desaturase activity vs. product precursor ratios. Lipids 35 (12) 1319-1323

Shafi, S., Welzel, D., Weidinger, G., Brown J.E. and Born G.V. (2000) Effect of reserpine treatment on low-density lipoproteins in arterial wall and internal organs of rats. Journal of Cardiovascular Pharmacology 35:686-92.

Collins, A.R., Brown, J.E., Bogdanov, M., Cadet, J., Cooke, M., Douki, T., Dunster, C., Eakins, J., Epe, B., Evans, M., Farmer, P., Gedik, C.M., Halliwell, B., Herbert, K., Hofer, T., Hutchinson, R., Jenner, A., Jones, G.D.D., Kasai, H., Kelly, F., Lloret, A., Loft, S., Lunec, J., McEwan, M., Moller, L., Olinki, R., Podmore, I., Poulsen, H., Ravanat, J-L., Rees, J.F., Reetz, F., Shertzer, B., Spiegelhalder, B., Turesky, R., Tyrrell, R., Vina, J., Vinicombe, D., Weimann, A., de Wergifosse, B. and Woods, S.G. (2000) Comparison of different methods of measuring 8-oxoguanine as a marker of oxidative DNA damage. Free Radical Research 32, 333-341.

Pourzand C., Watkin R.D., Brown, J.E. and Tyrrell, R.M. (1999) Ultraviolet A radiation induces immediate release of iron in human skin fibroblasts: The role of ferritin. Proceedings of the National Academy of Sciences, USA 96:6751-6756.

Brown, J.E. and Rice-Evans, C.A. (1998) Luteolin-rich artichoke extract protects low-density lipoprotein from oxidation in vitro. Free Radical Research 29:247-255.

Brown, J.E., Khodr, H., Hider, R.C. and Rice-Evans, C.A. (1998) Structural-dependence of flavonoid interactions with copper ions: Implications for their antioxidant properties. Biochemical Journal 330:1173-1178.

Riemersma, R.A., Perkins, D., Brown, A.J. and Brown, J.E. (1994) Linoleic acid and coronary artery disease. American Journal of Clinical Nutrition 59:949-950.

Brown, J.E. and Riemersma, R.A. (1994) Effect of dietary cholesterol on delta-6-desaturase. Scottish Medical Journal 39:61.

Scott, N.A., Jennings, P.E., Brown, J.E. and Belch, J.J.F. (1991) Gliclazide: a general free radical scavenger. European Journal of Pharmacology 208:175-177.

Brown, J.E. and Wahle, K.W.J. (1990) Effect of fish oil and vitamin E supplementation on lipid peroxidation and whole blood aggregation in man. Clinica Chimica Acta 193:147-156.

Wahle, K.W.J. and Brown, J.E. (1990) Plasma lipid peroxidation and platelet aggregation during high intakes of fish oil fatty acids. Fett Wissenschaft Technologie 92:326-330.

Brown, J.E. and Wahle, K.W.J. (1989) Fish oil supplements, lipid peroxidation and platelet aggregation in man. Biochemical Society Transactions 17:493.

Collins, M.D., Brown, J.E. and Jones, D. (1988) Brachybacterium faecium gen. nov. sp. nov., a Coryneform bacterium from poultry deep litter. International Journal of Systematic Bacteriology 38:45-48.

Abstracts (posters and oral presentations)

Wahle K.W.J. and Brown, J.E. (1989) Plasma lipid peroxidation and vitamin E supplementation during high intakes of fish oil. In: Vitamin E symposium, Bochum, West Germany.

Brown, J.E., Jennings, P.E., Bridges, A.B., Scott, N. and Belch, J.J.F. (1990) Atherosclerosis, diabetes and free radicals. In: Abstracts of the 635th Meeting of the Biochemical Society, Aberdeen, Scotland.

Jankowski, J., Bridges, A., Scott, N., Brown, J.E. and Belch J.J.F. (1990) Circulating free radicals and peptic ulcer disease. Gut 31 (10) A1183-A1183.

Brown, J.E. and Riemersma, R.A. (1992) Coronary heart disease and Δ6-desaturase: Methodological aspects of Δ6-desaturase measurement. Scottish Lipid Discussion Group Meeting, Glasgow, Scotland, UK.

Brown, J.E. and Riemersma, R.A. (1993) The effects of dietary cholesterol and isolation stress on Δ6-desaturase in the rat. Scottish Lipid Discussion Group Meeting, St. Andrews, Scotland, UK.

Brown, J.E. and Riemersma, R.A. (1993) Effect of dietary cholesterol on Δ6-desaturase. Scottish Society for Experimental Medicine, Edinburgh, Scotland, UK.

Brown, J.E., Lindsay, R.M. and Riemersma, R.A. (1993) Altered Δ6-desaturase activity and fatty acid composition in liver and plasma in the spontaneously diabetic BB rat. International Society for the Study of Fatty Acids and Lipids, Lugano, Switzerland.

Brown, J.E., Lindsay, R.M. Baird, J.D., Riemersma, R.A. (1996) Reduced Δ6-desaturation of linoleic acid in insulin treated BB diabetic rats. British Diabetic Association - Medical and Scientific Section Spring Meeting, Dublin, Ireland.

Brown, J.E. and Rice-Evans, C. (1996) Flavonoid structure and antioxidant activity. VIII Biennial Meeting of the International for Free Radical Research, Barcelona, Spain.

Paganga, G., Brown, J.E. and Rice-Evans, C. (1996) Simultaneous determination of the major families of polyphenolic compounds in vegetables by HPLC. VIII Biennial Meeting of the International for Free Radical Research, Barcelona, Spain.

Brown, J.E. (1997) Structure-antioxidant activity relationships of flavonoids. Mini-Symposium on Phytoprotectants. The Rank Prize Funds, Grasmere, England.

Brown, J.E., Khodr, H., Hider, R.C., Rice-Evans, C.A. (1998) Structural dependence of flavonoid interactions with Cu(II) ions: Implications for their antioxidant properties. World Congress of the Oxygen Club of California: Oxidants and Antioxidants in Biology, Santa Barbara, CA, USA.

Brown, J.E. and Rice-Evans, C.A. (1999) Artichoke extract protects LDL from oxidation. Meeting of the Society of Medicinal Plant Research, Amsterdam, The Netherlands.

Brown, J.E. and Rice-Evans C.A. (2000) Structural determinants of antioxidant activities in anthocyanidins. Meeting of the Society for Free Radical Research, Liverpool, England.

Tyrrell, R.M, Pourzand, C.A., Brown J.E., Hejmadi, V., Kvam E., Ryter, S. and Watkin R. (2000) Iron and heme release as key factors in the response of skin cells to UVA radiation. World Congress of the Oxygen Club of California: Oxidants and Antioxidants in Biology, Santa Barbara, CA, USA.

Brown, J.E. (2001) Flavonoids - A natural class of metal chelators relevant to health. London's Chemistry, London, England.

Au, A and Brown, J.E. (2002) The role of glycosylation on the antioxidant properties of polyphenols. XIth Meeting of the Society for Free Radical Research International, Paris, France

Harmer, J. and Brown, J.E. (2003) Properties of cyanidin-3-O-glucoside and malvidin 3-O-glucoside in relation to their ability to prevent LDL oxidation at physiological concentrations. 4th Nutrition and Health Conference, London, UK.

Harmer, J. and Brown J.E. (2004) The modulation of anthocyanin antioxidant activity by albumin. Summer Meeting of the Society for Free Radical Research Europe, Lodz, Poland.

Rahimuddin, S., Brown, J.E., Howell N.K. and Khoja, S.M. (2004) Effect of Luteolin and its glucosides on the prevention of UVA-induced oxidative damage in human skin fibroblasts. The Second Saudi Science Conference, Jeddah, Saudi Arabia.

Brown, J.E. (2004) The effect of physiologically relevant concentrations of dietary anthocyanins on their ability to prevent LDL oxidation in the presence and absence of serum albumin. Nutrition Society Annual Summer Meeting, Dublin, Ireland.

Rahimuddin, S., Brown, J.E., Howell N.K. and Khoja, S.M. (2004) Effect of Luteolin and its glucosides on the prevention of UVA-induced oxidative damage in human skin fibroblasts. SBMS Festival of Research, University of Surrey, Guildford, UK.

Parry B.M., Brown J.E., S.M. Horton, J.M. Stilwell, D.B. Clarke, J.M. Lawrence, M. Raats, L. Storey and R.M. Rainsbury. (2005) Investigation of the phytoestrogen intake of group of postmenopausal women previously treated for breast cancer. Food Standards Agency Meeting, Gatwick, UK.

Stoupi S., Clifford M.N., Kuhnert N., Brown J.E. and Williamson G. (2006) Gut flora metabolism of flavan-3-ols. SBMS Festival of Research, University of Surrey, Guildford, UK.

Parry B.M., Brown J.E., S.M. Horton, J.M. Stilwell, D.B. Clarke, J.M. Lawrence, M. Raats, L. Storey and R.M. Rainsbury. (2006) Investigation of the phytoestrogen intake of group of postmenopausal women previously treated for breast cancer. Food Standards Agency Meeting, Slaley Hall, Hexham, UK.

Brown, J.E., J.W. Tong, B.M. Parry, S.M. Horton, J.M. Stilwell, D.B. Clarke, J.M. Lawrence, M. Raats, L. Storey and R.M. Rainsbury. (2006) Creation of a new phytoestrogen database for the assessment of dietary intakes of isoflavones, coumestans and lignans in a group of postmenopausal women previously treated for breast cancer. Soy and Health Conference, Düsseldorf, Germany.

Parry B.M., Brown J.E., S.M. Horton, J.M. Stilwell, D.B. Clarke, J.M. Lawrence, M. Raats, L. Storey and R.M. Rainsbury. (2007) Investigation of the phytoestrogen intake of group of postmenopausal women previously treated for breast cancer. Food Standards Agency Meeting, Slaley Hall, Hexham, UK.

Brown J.E., K. Chana, C. Mahende. (2007) Differences in the absorption and excretion of soy milk isoflavones in Oriental and Caucasian men. Nutrition Society Annual Meeting, Coleraine, N. Ireland

Stoupi S., Clifford M.N., Williamson G and Brown J.E. (2007) Gut flora metabolism of (-)epicatechin. SBMS Festival of Research, University of Surrey, Guildford, UK.

Jamil D., Brown J.E., Driscoll D., Howell N. (2007) Gas chromatographic (GC) and GC-MS analysis of volatile oil components of Thymbra spicata L. and Thymus syriaca Boiss. var syriaca. SBMS Festival of Research, University of Surrey, Guildford, UK.

Parry B.M., Lawrence J.M., Storey L., Brown J.E., Clarke D.B., Raats M., Horton S.M., Stilwell J.M., and Rainsbury R.M. (2007) Food choice and phytoestrogen consumption in women previously treated for post-menopausal breast cancer. WCRF and AICR Second Expert Launch Conference, Washington DC, USA.

Brown J.E., K. Chana, C. Mahende. (2007) Absorption and excretion of soy milk isoflavones differs between Oriental and Caucasian men. University of Surrey Festival of Research, November 2007, Guildford, Surrey, UK

Stoupi, S., Clifford, M.N., Williamson, G. and Brown, J.E. (2007) A comparison of the biotransformation of procyanidin B2 and (-)epicatechin by human colonic bacteria. 3rd International Conference on Polyphenols and Health, Kyoto, Japan.

Parry B.M., Lawrence J.M., Storey L., Brown J.E., Clarke D.B., Raats M., Horton S.M., Stilwell J.M., and Rainsbury R.M. (2008) Food choice and phytoestrogen consumption in women previously treated for post-menopausal breast cancer. Breast Cancer Research 2008, The Royal Society, London, UK.

Jamil D., Brown J.E., Driscoll D. Howell N.K. (2008) Composition and antioxidant properties of thyme and thymbra. FHMS Festival of Research, University of Surrey, Guildford, UK.

Mssallem-Al M, Driscoll D., Frost G., and Brown J.E. (2008) Carbohydrate bioavailability in vitro and in vivo. FHMS Festival of Research, University of Surrey, Guildford. UK.

Stoupi, S., Williamson G., Drynan J.W., Brown J.E., and Clifford M.N. (2008) A comparison of the biotransformation of (-)-epicatechin and procyanidin B2 by human colonic bacteria. FHMS Festival of Research, University of Surrey, Guildford. UK.

Brown, J.E., Cropp, E., Rizzo, V. (2009) Carotenoid content and antioxidant activity of fourteen tomato ketchups available in the UK. FHMS Festival of Research, University of Surrey, Guildford. UK.

Al-Mssallem, M., Frost G., Hampton S. and Brown J.E. (2009) A study of Hassawi rice in terms of its carbohydrate hydrolysis in vitro and glycaemic and insulinaemic indices in vivo. FHMS Festival of Research, University of Surrey, Guildford. UK.

Al-Mssallem, M., Frost G. and Brown J.E. (2009) Compositional analysis of Hassawi rice (Oryza sativa L.) and its associated glycaemic and insulinaemic indices. Nutrition Society Annual Meeting, Guildford, Surrey, UK.

Brown, J.E., Cropp, E. and Rizzo, V. (2009) Carotenoid content and antioxidant activity of fourteen tomato ketchups available in the UK. Nutrition Society Annual Meeting, Guildford, Surrey, UK.

Jamil, D.M., Brown J.E., Driscoll, D. and Howell, NK. (2009) Characterization and antioxidant activity of the volatile oils of Thymus Syriacus Boiss. var syriacus and Thymbra spicata L. grown wild in Kurdistan-Iraq. Nutrition Society Annual Meeting, Guildford, Surrey, UK.