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Dr Roberta Bonomo

Postgraduate Research Student


My research project


Roberta Bonomo, Guido Cavaletti, Debra Skene (2020)Metabolomics markers in Neurology: current knowledge and future perspectives for therapeutic targeting., In: Expert Review of Neurotherapeutics Taylor and Francis

Introduction: Metabolomics is an emerging approach providing new insights into the 7 metabolic changes and underlying mechanisms involved in the pathogenesis of 8 neurological disorders. 9 Areas covered: Here, we present an overview of the current knowledge of metabolic 10 profiling (metabolomics) to provide critical insight on the role of biochemical markers and metabolic alterations in neurological diseases. Expert opinion: Elucidation of characteristic metabolic alterations in neurological disorders is crucial for a better understanding of their pathogenesis, and for identifying potential biomarkers and drug targets. Nevertheless, discrepancies in diagnostic criteria, sample handling protocols, and analytical methods still affect the generalizability of current study results.