Professor Hardev Pandha
Professor of Medical Oncology
Academic and research departments
School of Biosciences and Medicine, Faculty of Health and Medical Sciences.Biography
Hardev Pandha is a clinician scientist and medical oncologist who graduated in medicine at the University of Birmingham. He trained in internal medicine and subsequently in medical oncology at the Royal Postgraduate Medical School at Hammersmith Hospital, London. He completed his PhD (Imperial College) in the Imperial Cancer Research Fund labs at the Hammersmith. He was a visiting fellow at Stanford University prior to completing his medical oncology training at the Royal Marsden Hospital, London. He was a senior lecturer in tumour immunology and medical oncology at St Georges, University of London in 2000 before being appointed Prof of Urological Oncology at the University of Surrey in 2006.
His areas of expertise include the management of patients with Urological cancers and malignant melanoma. He has a key interest in early phase clinical trials involving targeted agents and the translational aspects of novel therapies. His portfolio includes gene and viral therapy as well as immunotherapy and small molecule inhibitors. His laboratory interests reflect this and in particular a combination of novel and biological therapies with more conventional treatments. His lab team have evolved a robust infrastructure of patient sample procurement and biobanking for translational research.
Research
Research interests
- Tumour immunology
- Urological cancer
- Gene therapy
My publications
Highlights
- The Role of Circular RNAs in Pancreatic Ductal Adenocarcinoma and Biliary-Tract Cancers. Limb C, Liu DSK, Veno MT, Rees E, Krell J, Bagwan IN, Giovannetti E, Pandha H, Strobel O, Rockall TA, Frampton AE.Limb C, et al. Cancers (Basel). 2020 Nov 4;12(11):E3250.
- An integrative multi-omics analysis to identify candidate DNA methylation biomarkers related to prostate cancer risk. Wu L, Yang Y, Guo X, Shu XO, Cai Q, Shu X, Li B, Tao R, Wu C, Nikas JB, Sun Y, Zhu J, Roobol MJ, Giles GG, Brenner H, John EM, Clements J, Grindedal EM, Park JY, Stanford JL, Kote-Jarai Z, Haiman CA, Eeles RA, Zheng W, Long J; PRACTICAL consortium; CRUK Consortium; BPC3 Consortium; CAPS Consortium; PEGASUS Consortium.Wu L, et al. Nat Commun. 2020 Aug 6;11(1):3905.
- A Genetic Risk Score to Personalize Prostate Cancer Screening, Applied to Population Data. Huynh-Le MP, Fan CC, Karunamuni R, Walsh EI, Turner EL, Lane JA, Martin RM, Neal DE, Donovan JL, Hamdy FC, Parsons JK, Eeles RA, Easton DF, Kote-Jarai Z, Amin Al Olama A, Benlloch Garcia S, Muir K, Grönberg H, Wiklund F, Aly M, Schleutker J, Sipeky C, Tammela TL, Nordestgaard BG, Key TJ, Travis RC, Pharoah PDP, Pashayan N, Khaw KT, Thibodeau SN, McDonnell SK, Schaid DJ, Maier C, Vogel W, Luedeke M, Herkommer K, Kibel AS, Cybulski C, Wokolorczyk D, Kluzniak W, Cannon-Albright LA, Brenner H, Schöttker B, Holleczek B, Park JY, Sellers TA, Lin HY, Slavov CK, Kaneva RP, Mitev VI, Batra J, Clements JA, Spurdle AB, Teixeira MR, Paulo P, Maia S, Pandha H, Michael A, Mills IG, Andreassen OA, Dale AM, Seibert TM; Australian Prostate Cancer BioResource (APCB); PRACTICAL Consortium.Huynh-Le MP, et al. Cancer Epidemiol Biomarkers Prev. 2020 Sep;29(9):1731-1738.
- The effect of sample size on polygenic hazard models for prostate cancer. Karunamuni RA, Huynh-Le MP, Fan CC, Eeles RA, Easton DF, Kote-Jarai Z, Amin Al Olama A, Benlloch Garcia S, Muir K, Gronberg H, Wiklund F, Aly M, Schleutker J, Sipeky C, Tammela TLJ, Nordestgaard BG, Key TJ, Travis RC, Neal DE, Donovan JL, Hamdy FC, Pharoah P, Pashayan N, Khaw KT, Thibodeau SN, McDonnell SK, Schaid DJ, Maier C, Vogel W, Luedeke M, Herkommer K, Kibel AS, Cybulski C, Wokolorczyk D, Kluzniak W, Cannon-Albright L, Brenner H, Schöttker B, Holleczek B, Park JY, Sellers TA, Lin HY, Slavov C, Kaneva R, Mitev V, Batra J, Clements JA, Spurdle A; Australian Prostate Cancer BioResource (APCB), Teixeira MR, Paulo P, Maia S, Pandha H, Michael A, Mills IG, Andreassen OA, Dale AM, Seibert TM; PRACTICAL Consortium.Karunamuni RA, et al. Eur J Hum Genet. 2020 Oct;28(10):1467-1475.
- Genomic analysis of male puberty timing highlights shared genetic basis with hair colour and lifespan. Hollis B, Day FR, Busch AS, Thompson DJ, Soares ALG, Timmers PRHJ, Kwong A, Easton DF, Joshi PK, Timpson NJ; PRACTICAL Consortium; 23andMe Research Team, Ong KK, Perry JRB.Hollis B, et al.Nat Commun. 2020 Mar 24;11(1):1536.
- Modifying the Non-muscle Invasive Bladder Cancer Immune Microenvironment for Optimal Therapeutic Response. Annels NE, Simpson GR, Pandha H.Annels NE, et al. Front Oncol. 2020 Feb 18;10:175
- The PERK Inhibitor GSK2606414 Enhances Reovirus Infection in Head and Neck Squamous Cell Carcinoma via an ATF4-Dependent Mechanism. McLaughlin M, Pedersen M, Roulstone V, Bergerhoff KF, Smith HG, Whittock H, Kyula JN, Dillon MT, Pandha HS, Vile R, Melcher AA, Harrington KJ.McLaughlin M, et al. Mol Ther Oncolytics. 2020 Jan 17;16:238-249.
- Rationale and design of the POLEM trial: avelumab plus fluoropyrimidine-based chemotherapy as adjuvant treatment for stage III mismatch repair deficient or POLE exonuclease domain mutant colon cancer: a phase III randomised study. Lau D, Kalaitzaki E, Church DN, Pandha H, Tomlinson I, Annels N, Gerlinger M, Sclafani F, Smith G, Begum R, Crux R, Gillbanks A, Wordsworth S, Chau I, Starling N, Cunningham D, Dhillon T.Lau D, et al. ESMO Open. 2020 Feb;5(1):e000638.
- PBX3 in Cancer. Morgan R, Pandha HS.Morgan R, et al. Cancers (Basel). 2020 Feb 13;12(2):431.
- APOBEC3B-mediated corruption of the tumor cell immunopeptidome induces heteroclitic neoepitopes for cancer immunotherapy. Driscoll CB, Schuelke MR, Kottke T, Thompson JM, Wongthida P, Tonne JM, Huff AL, Miller A, Shim KG, Molan A, Wetmore C, Selby P, Samson A, Harrington K, Pandha H, Melcher A, Pulido JS, Harris R, Evgin L, Vile RG.Driscoll CB, et al.. Nat Commun. 2020 Feb 7;11(1):790.
- A Specific Blood Signature Reveals Higher Levels of S100A12: A Potential Bladder Cancer Diagnostic Biomarker Along With Urinary Engrailed-2 Protein Detection. Elamin AA, Klunkelfuß S, Kämpfer S, Oehlmann W, Stehr M, Smith C, Simpson GR, Morgan R, Pandha H, Singh M. Front Oncol. 2020 Jan 9;9:1484.
- The Open University's first one-day symposium on treatment-emergent neuroendocrine prostate cancer. Mather RL, Andrews H, Pandha H, Jachetti E, Micallef J, Wang Y, Crea F. Future Oncol. 2020 Feb;16(6):147-149.
Publications
Zaidi Shane, Diaz Rosa Maria, Kottke Tim, Evgin Laura, Shim Kevin G., Rommelfanger Diana, Boisgerault Nicolas, Selby Peter, Thompson Jill, Ilett Elizabeth, Coffey Matt, Pandha Hardev, Harrington Kevin, Melcher Alan, Vile Richard (2017)Subversion of NK-cell and TNFα Immune Surveillance Drives Tumor Recurrence, In: Cancer Immunology Research5(11)pp. 1029-1045 American Association for Cancer Research
Kostalas Marcos (2020)Evaluation of the effects of oncolytic vaccinia virus on colorectal liver metastases in cell lines and in organotypic cultures. University of Surrey
Rogers William (2020)Profiling and targeting HOX-PBX dimers in adult and paediatric glioblastoma as a novel therapy. University of Surrey
Horvath A, Simpson GR, Coffin RS, Mostafid H, Pandha H (2010)NOVEL INTRAVESICAL THERAPY FOR NON MUSCLE INVASIVE BLADDER CANCER USING A GENETICALLY MODIFIED ONCOLYTIC HERPES SIMPLEX VIRUS, In: EUR UROL SUPPL9(6)pp. 646-646
Guy M, Lophatonanon A, Muir K, Vinuela A, Brown AA, Freedman M, Conti DV, Easton D, Coetzee GA, Eeles RA, Kote-Jarai Z, Li Q, Al Olama AA, Dadaev T, Hazelett DJ, Leongamornlert D, Saunders EJ, Stephens S, Cieza-Borrella C, Southey MC, Whitmore I, Garcia SB, Giles GG, Fitzgerald L, Gronberg H, Wiklund F, Aly M, Henderson BE, Wahlfors T, Schumacher F, Haiman CA, Schleutker J, Tammela TL, Nordestgaard BG, Key TJ, Travis RC, Pharoah P, Neal DE, Donovan JL, Hamdy FC, Pashayan N, Khaw K-T, Stanford JL, Thibodeau SN, Mcdonnell SK, Luedeke M, Schaid DJ, Maier C, Vogel W, Herkommer K, Kibel AS, Cybulski C, Wokolorczyk D, Kluzniak W, Cannon-Albright L, Park JY, Brenner H, Butterbach K, Arndt V, Sellers T, Lin H-Y, Slavov C, Kaneva R, Mitev V, Batra J, Paulo P, Clements JA, Spurdle A, Teixeira MR, Maia S, Pandha H, Michael A, Kierzek A, Govindasami K (2015)Multiple novel prostate cancer susceptibility signals identified by fine-mapping of known risk loci among Europeans, In: HUMAN MOLECULAR GENETICS24(19)pp. 5589-5602 OXFORD UNIV PRESS
Daniels TR, Neacato II, Rodriguez JA, Pandha HS, Morgan R, Penichet ML (2010)Disruption of HOX activity leads to cell death that can be enhanced by the interference of iron uptake in malignant B cells, In: LEUKEMIA24(9)pp. 1555-1565 NATURE PUBLISHING GROUP
Heinemann L, Simpson GR, Annels NE, Vile R, Melcher A, Prestwich R, Harrington KJ, Pandha HS (2010)The Effect of Cell Cycle Synchronization on Tumor Sensitivity to Reovirus Oncolysis, In: MOLECULAR THERAPY18(12)pp. 2085-2093 NATURE PUBLISHING GROUP
Enting D, Iannitto ML, Pandha H, Chowdhury S, Hayday A (2015)Effects of Concomitant Therapies on gamma delta T Cell Responses to Zoledronate in Patients with Advanced Prostate Cancer, In: CLINICAL ONCOLOGY27(3)pp. E4-E4 ELSEVIER SCIENCE LONDON
Crabb SJ, Douglas J, Annels NE, Morgan R, Packham G, Pandha HS (2014)Engrailed-2 (EN2) protein expression and prognosis in bladder cancer following radical cystectomy (RC)., In: JOURNAL OF CLINICAL ONCOLOGY32(15)
Appleton ES, Turnbull S, Ralph C, West E, Scott K, Harrington K, Pandha H, Melcher A (2015)Talimogene laherparepvec in the treatment of melanoma, In: EXPERT OPINION ON BIOLOGICAL THERAPY15(10)pp. 1517-1530 TAYLOR & FRANCIS LTD
Donnelly OG, Errington-Mais F, Prestwich R, Harrington K, Pandha H, Vile R, Melcher AA (2011)Recent Clinical Experience With Oncolytic Viruses., In: Curr Pharm Biotechnol
Simpson GR, Ajaz M, Launchbury FA, Bolton G, Melcher AA, Harrington KJ, Au GG, Shafren DR, Pandha HS (2014)Major synergy between Coxsackievirus A21 (CAVATAK (TM)) and radiotherapy or chemotherapy in bladder cancer, In: HUMAN GENE THERAPY25(12)pp. A13-A13
Massuger LFAG, Fitzgerald LM, Cook LS, Cannon-Albright L, Hooning MJ, Pike MC, Bolla MK, Luedeke M, Teixeira MR, Goodman MT, Kar SP, Beesley J, Kote-Jarai ZA, Al Olama AA, Michailidou K, Tyrer J, Lawrenson K, Lindstrom S, Ramus SJ, Thompson DJ, Kibel AS, Dansonka-Mieszkowska A, Moisse M, Aly M, Rossing MA, Beckmann MW, Sanderson M, Southey MC, Jones M, Lush M, Hildebrandt MAT, Hou M-F, Whittemore AS, Michael A, Dieffenbach AK, Gentry-Maharaj A, Wolk A, Monteiro A, Peixoto A, Kierzek A, Rahman N, Schoemaker MJ, Garcia-Closas M, Bogdanova N, Le ND, Orr N, Wentzensen N, Pashayan N, Peterlongo P, Guenel P, Wu AH, Cox A, Rudolph A, Gonzalez-Neira A, Lindblom A, Swerdlow A, Ziogas A, Ekici AB, Broberg P, Brennan P, Paulo P, Webb PM, Fasching PA, Devilee P, Wang Q, Cai Q, Li Q, Kaneva R, Blomqvist C, Burwinkel B, Karlan BY, Nordestgaard BG, Phelan C, McLean C, Pearce CL, Vachon C, Cybulski C, Slavov C, Stephenson RA, Butzow R, Kopperud RK, Schmutzler RK, MacInnis RJ, Hoover RN, Winqvist R, Ness R, Milne RL, Travis RC, Hogdall CK, Stegmaier C, Maier C, Ambrosone CB, Teerlink CC, Kang D, Tessier DC, Schaid DJ, Stram DO, Cramer DW, Olson SH, Benlloch S, McDonnell SK, Tworoger SS, Maia SA, Berndt S, Lee SC, Teo S-H, Thibodeau SN, Bojesen SE, Pejovic T, Neal DE, Eccles D, Flesch-Janys D, Gapstur SM, Kjaer SK, Tammela TLJ, Doerk T, Bruening T, Wahlfors T, Key TJ, Edwards TL, Yannoukakos D, Edwards DRV, Wokozorczyk D, Levine DA, Sawyer EJ, Bandera EV, Poole EM, Goode EL, Khusnutdinova E, Hogdall E, Kosma V-M, Menon U, Hamann U, Mitev V, Setiawan VW, Kristensen V, Arndt V, Vogel W, Zheng W, Sieh W, Modugno F, Song F, Bruinsma F, Heitz F, Hamdy FC, Wiklund F, Giles GG, Olsson H, Wildiers H, Ulmer H-U, Gao Y-T, Blot WJ, Kluzniak W, Shu X-O, Schumacher F, Freedman ML, Berchuck A, Dunning AM, Salvesen HB, Pandha H, Risch HA, Darabi H, Nevanlinna H, Gronberg H, Brenner H, Brauch H, Anton-Culver H, Song H, Sellers TA, Simard J, Haiman CA, Spurdle A, Hunter DJ, Henderson BE, Kraft P, Chanock SJ, Couch FJ, Vergote I, Lim H-Y, McNeish I, Campbell I, Gronwald J, Lubinski J, Stanford JL, Bentez J, Doherty JA, Permuth JB, Chenevix-Trench G, Schmidt MK, Riggan M, Hall P, Gayther SA, Easton DF, Eeles R, Pharoah PDP, Lambrechts D, Dennis J, Chang-Claude J, Donovan JL, Schildkraut JM, Schleutker J, Hopper JL, Kupryjanczyk J, Park JY, Figueroa J, Clements JA, Pow-Sang J, Knight JA, Peto J, Cunningham JM, Batra J, Czene K, Lu KH, Herkommer K, Khaw K-T, Chen K, Matsuo K, Muir K, Offitt K, Moysich KB, Aittomaki K, Odunsi K, Kiemeney LA (2016)Genome-Wide Meta-Analyses of Breast, Ovarian, and Prostate Cancer Association Studies Identify Multiple New Susceptibility Loci Shared by at Least Two Cancer Types, In: CANCER DISCOVERY6(9)pp. 1052-1067 AMER ASSOC CANCER RESEARCH
De Paoli M, Perco P, Muehlberger I, Lukas A, Pandha H, Morgan R, Feng GJ, Marquette C (2015)Disease map-based biomarker selection and pre-validation for bladder cancer diagnostic, In: BIOMARKERS20(5)pp. 328-337 TAYLOR & FRANCIS LTD
Alharbi RA, Pettengell R, Pandha HS, Morgan R (2012)The role of HOX genes in normal hematopoiesis and acute leukemia., In: Leukemia Nature Publishing Group
Twigger K, Roulstone V, Kyula J, Karapanagiotou EM, Syrigos KN, Morgan R, White C, Bhide S, Nuovo G, Coffey M, Thompson B, Jebar A, Errington F, Melcher AA, Vile RG, Pandha HS, Harrington KJ (2012)Reovirus exerts potent oncolytic effects in head and neck cancer cell lines that are independent of signalling in the EGFR pathway., In: BMC Cancer12pp. 368-?
Patel Poulam M., Ottensmeier Christian H., Mulatero Clive, Lorigan Paul, Plummer Ruth, Pandha Hardev, Elsheikh Somaia, Hadjimichael Efthymios, Villasanti Naty, Adams Sally E., Cunnell Michelle, Metheringham Rachael L., Brentville Victoria A., Machado Lee, Daniels Ian, Gijon Mohamed, Hannaman Drew, Durrant Lindy G. (2018)Targeting gp100 and TRP-2 with a DNA vaccine: Incorporating T cell epitopes with a human IgG1 antibody induces potent T cell responses that are associated with favourable clinical outcome in a phase I/II trial, In: OncoImmunology7(6)e1433516pp. e1433516-1 Taylor & Francis
Bolton GC, Simpson GR, Coffey M, Harrington K, Morgan R, Annels N, Launchbury FA, Ajaz M, Pandha H (2014)Resistance to Oncolytic Reovirus is associated with high expression of Yes-Associated Protein-1 (YAP-1) in Head and Neck Cancer, In: HUMAN GENE THERAPY25(12)pp. A12-A13
Gore ME, Nutting CM, Pandha HS, Melcher AA, Vile RG, Harrington KJ (2008)T-cell responses to survivin in cancer patients undergoing radiation therapy, In: Clinical Cancer Research14(15)pp. 4883-4883
Middleton GW, Annels NE, Pandha HS (2012)Are we ready to start studies of Th17 cell manipulation as a therapy for cancer?, In: Cancer Immunol Immunother61(1)pp. 1-7
Ilett E, Kottke T, Donnelly O, Thompson J, Willmon C, Diaz R, Zaidi S, Coffey M, Selby P, Harrington K, Pandha H, Melcher A, Vile R (2014)Direct, Cytokine-Conditioned, In Vivo Cell Loading for Systemic Delivery of Oncolytic Viruses, In: MOLECULAR THERAPY22pp. S245-S245
Comins C, Simpson Guy, Rogers William, Relph Kate, Harrington K, Melcher A, Roulestone V, Kyula J, Pandha Hardev (2018)Synergistic anti-tumour effects of rapamycin and oncolytic reovirus, In: Cancer Gene Therapy25pp. 148-160 Nature Publishing Group
Kottke T, Donnelly O, Boisgerault N, Diaz R, Rommelfanger-Konkol D, Pulido J, Thompson J, Mukhopadhyay D, Knutson K, Behrens M, Kaspar R, Coffey M, Selby P, Harrington K, Melcher A, Pandha H, Vile R (2013)Tumor Relapse Is Associated with an Innate Immune Resistant Phenotype across Tumor and Treatment Types Which Can Be Targeted with Rational Second Line Therapies, In: MOLECULAR THERAPY21pp. S249-S249
Meyer B, Denyer M, Morgan R, Pandha H (2007)Cellular effects of phosphoramide mustard, the active metabolite of cyclophosphamide, on naturally-occuring human CD4(+) CD25(+) regulatory T cells, In: JOURNAL OF IMMUNOTHERAPY30(8)pp. 887-887
McGrath SE, Michael A, Pandha H, Morgan R (2013)Engrailed homeobox transcription factors as potential markers and targets in cancer., In: FEBS Lett587(6)pp. 549-554
Blanchard M, Shim KG, Grams MP, Rajani K, Diaz RM, Furutani KM, Thompson J, Olivier KR, Park SS, Markovic SN, Pandha H, Melcher A, Harrington K, Zaidi S, Vile R (2015)Definitive Management of Oligometastatic Melanoma in a Murine Model Using Combined Ablative Radiation Therapy and Viral Immunotherapy, In: INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS93(3)pp. 577-587 ELSEVIER SCIENCE INC
Annels NE, Simpson GR, Bokaee S, Riley C, Denyer M, Pandha H, Morgan R (2012)Modulation of Regulatory T Cells by Targeting The NFAT-FOXP3 Protein: Protein Interaction, In: JOURNAL OF IMMUNOTHERAPY35(9)pp. 775-775
Javed S, Morgan R, Hindley R, Bott S, Eden C, Pandha H, Langley S (2014)Urinary engrailed-2 levels in healthy volunteers, patients on active surveillance and following radical prostate cancer treatment, In: BJU INTERNATIONAL113pp. 43-44
Heinemann L, Kottke T, Vile R, Coffey MC, Harrington K, Melcher A, Pandha HS (2008)Synergistic Anti-Tumor Activity of Oncolytic Reovirus and Docetaxel in a PC-3 Prostate Cancer Mouse Model, In: JOURNAL OF IMMUNOTHERAPY31(9)pp. 951-952
Kottke T, Donnelly O, Ilett E, Thompson J, Diaz R, Coffey M, Selby P, Pandha H, Harrington K, Melcher A, Vile R (2013)In Vivo Expansion of a Recipient Population of Cell Carriers Allows for Highly Effective Systemic Delivery of Oncolytic Reovirus Even in the Presence of Neutralizing Antibody, In: MOLECULAR THERAPY21pp. S7-S7
Knight LA, McCavigan AM, Logan GE, Berge V, Sherif A, Pandha Hardev, Warren AY, Davidson C, Uprichard A, Blayney JK, Price B, Jellema GL, Svindland A, McDade SS, Eden CG, Foster C, Mills IG, Waugh DJ, Neal DE, Mason MD, Kay EW, Harkin DP, Watson RW, Clarke NW, Kennedy RD, Walker SM (2017)Molecular Subgroup of Primary Prostate Cancer Presenting with Metastatic Biology, In: European Urology72(4)pp. 509-518 Elsevier
Harrington K, Pandha H, D'Ambrosio C, Heenan S, Hyde N, Di Palma S, Nutting C, Relph K (2009)Indium-labelled Autologous Dendritic Cells Migrate to Local Lymph Nodes after Intratumoural Injection in Head and Neck Cancer Patients, In: CLINICAL ONCOLOGY21(4)pp. 363-364 ELSEVIER SCIENCE LONDON
Annels NE, Pandha H (2013)Immunotherapy, In: Prostate Cancer: A Comprehensive Perspectivepp. 925-934
Jennings VA, Ilett EJ, Scott KJ, West EJ, Vile R, Pandha H, Harrington K, Young A, Hall GD, Coffey M, Selby P, Errington-Mais F, Melcher AA (2014)Lymphokine-activated killer and dendritic cell carriage enhances oncolytic reovirus therapy for ovarian cancer by overcoming antibody neutralization in ascites, In: INTERNATIONAL JOURNAL OF CANCER134(5)pp. 1091-1101 WILEY-BLACKWELL
Verbeke CS, Hamdan S, Booth J, Pandha HS, Blair GE (2006)Limited expression of the Coxsackie and Adenovirus Receptor in pancreatic cancer may reduce suitability of adenoviral gene therapy, In: JOURNAL OF PATHOLOGY210pp. 2-2
Anesti A-M, Simpson GR, Price T, Pandha HS, Coffin RS (2010)Expression of RNA interference triggers from an oncolytic herpes simplex virus results in specific silencing in tumour cells in vitro and tumours in vivo, In: BMC CANCER10ARTN 4pp. ?-? BIOMED CENTRAL LTD
Enting D, Iannitto ML, Binda E, Eberl M, Pandha H, Hayday A (2013)Effects of concomitant therapies on gd T cell responses to zoledronate in patients with advanced prostate cancer, In: IMMUNOLOGY140pp. 69-69
Ismail M, Morgan R, Harrington K, Davies J, Pandha H (2009)Enhancing prostate cancer cryotherapy using tumour necrosis factor related apoptosis-inducing ligand (TRAIL) sensitisation in an in vitro cryotherapy model, In: CRYOBIOLOGY59(2)pp. 207-213 ACADEMIC PRESS INC ELSEVIER SCIENCE
Boisgerault N, Kottke T, Pulido J, Thompson J, Diaz RM, Rommelfanger-Konkol D, Embry A, Saenz D, Poeschla E, Pandha H, Harrington K, Melcher A, Selby P, Vile R (2013)Functional Cloning of Recurrence-specific Antigens Identifies Molecular Targets to Treat Tumor Relapse, In: MOLECULAR THERAPY21(8)pp. 1507-1516 NATURE PUBLISHING GROUP
Boisgerault N, Pulido J, Kottke T, Donnelly O, Celis E, Thompson J, Diaz R, Harrington K, Pandha H, Selby P, Melcher A, Vile R (2013)Tumor Recurrences Share Immunogenic Antigens across Both Tumor Types and Primary Treatments Which Can Be Therapeutically Targeted with VSV-cDNA Libraries, In: MOLECULAR THERAPY21pp. S152-S152
Killick E, Morgan R, Launchbury F, Bancroft E, Page E, Castro E, Kote-Jarai Z, Aprikian A, Blanco I, Clowes V, Domchek S, Douglas F, Eccles D, Evans DG, Harris M, Mitchell G, Kirk J, Lam J, Lindeman G, Pachter N, Selkirk C, Tucker K, Zgajnar J, Eeles R, Pandha H (2013)Role of Engrailed-2 (EN2) as a prostate cancer detection biomarker in genetically high risk men., In: Sci Rep3pp. 2059-?
Ismail M, Morgan R, Davies J, Pandha H (2008)Immunoregulatory effects of cryo-treated prostate cancer cells on human dendritic cells using a novel in vitro cryotherapy model, In: JOURNAL OF UROLOGY179(4)pp. 48-48
Errico MC, Felicetti F, Bottero L, Mattia G, Boe A, Felli N, Petrini M, Bellenghi M, Pandha HS, Calvaruso M, Tripodo C, Colombo MP, Morgan R, Care A (2013)The abrogation of the HOXB7/PBX2 complex induces apoptosis in melanoma through the miR-221&222-c-FOS pathway, In: INTERNATIONAL JOURNAL OF CANCER133(4)pp. 879-892 WILEY-BLACKWELL
Davies NM, Gaunt TR, Lewis SJ, Holly J, Donovan JL, Hamdy FC, Kemp JP, Eeles R, Easton D, Kote-Jarai Z, Al Olama AA, Benlloch S, Muir K, Giles GG, Wiklund F, Gronberg H, Haiman CA, Schleutker J, Pashayan N, Nordestgaard BG, Travis RC, Neal D, Khaw K-T, Stanford JL, Blot WJ, Thibodeau S, Maier C, Brenner H, Kibel AS, Cybulski C, Cannon-Albright L, Park J, Kaneva R, Batra J, Teixeira MR, Pandha H, Lathrop M, Smith GD, Martin RM (2015)The effects of height and BMI on prostate cancer incidence and mortality: a Mendelian randomization study in 20,848 cases and 20,214 controls from the PRACTICAL consortium, In: CANCER CAUSES & CONTROL26(11)pp. 1603-1616 SPRINGER
Ravaud A, Motzer RJ, Pandha H, Staehler M, George DJ, Pantuck A, Patel A, Gerletti P, Chen L, Patard J (2012)SUNITINIB TREATMENT OF RENAL ADJUVANT CANCER (S-TRAC): A RANDOMIZED, DOUBLE-BLIND, PHASE III STUDY OF SUNITINIB VS. PLACEBO IN SUBJECTS AT HIGH RISK OF RECURRENT RENAL CELL CARCINOMA (RCC), In: ANNALS OF ONCOLOGY23pp. 292-293
Michael A, Riley C, Bokaee S, Denyer M, Pandha HS, Annels NE (2011)EN2: A candidate antigen for the development of targeted therapies in ovarian cancer., In: JOURNAL OF CLINICAL ONCOLOGY29(15) AMER SOC CLINICAL ONCOLOGY
Shears L, Plowright L, Harrington K, Pandha HS, Morgan R (2008)Disrupting the Interaction Between HOX and PBX Causes Necrotic and Apoptotic Cell Death in the Renal Cancer Lines CaKi-2 and 769-P, In: J UROLOGY180(5)pp. 2196-2201 ELSEVIER SCIENCE INC
Michael A, McGrath S, Annels N, Denyer M, Morgan R, Pandha H (2015)Engrailed 2 protein (EN2) as a novel biomarker in epithelial ovarian cancer, In: EUROPEAN JOURNAL OF CANCER51pp. S91-S91
Kottke T, Donnelly O, Boisgerault N, Diaz R, Thompson J, Chester J, Pandha H, Harrington K, Melcher A, Vile R (2012)Characterization of the Mechanisms of Tumor Dormancy and Recurrence Following Front Line Immuno-, Viro- or Suicide Gene-, Therapy, In: MOLECULAR THERAPY20pp. S268-S268
Annels NE, Riley C, Bokaee S, Denyer M, Simpson GR, Pandha H (2010)EN2: A Novel Immunotherapeutic Target for Melanoma, In: J IMMUNOTHER33(8)pp. 891-891
Kelly Z, Pandha H, Morgan R, Michael A (2012)HXR9 AND PARP INHIBITION -A NOVEL THERAPEUTIC IN OVARIAN CANCER, In: ANNALS OF ONCOLOGY23pp. 325-325
Lord R, Nair S, Schache A, Spicer J, Somaihah N, Khoo V, Pandha H (2007)Low dose metronomic oral cyclophosphamide for hormone resistant prostate cancer: A phase II study, In: JOURNAL OF UROLOGY177(6)pp. 2136-2140 ELSEVIER SCIENCE INC
Donnelly O, Harrington K, Melcher A, Pandha H (2013)Live viruses to treat cancer, In: JOURNAL OF THE ROYAL SOCIETY OF MEDICINE106(8)pp. 310-314 ROYAL SOC MEDICINE PRESS LTD
Heinemann L, Simpson G, Harrington K, Melcher A, Coffey MC, Pandha HS (2008)Synergistic anti-tumour activity of oncolytic Reovirus and cisplatin in a B16.F10 mouse melanoma model, In: EJC SUPPLEMENTS6(12)pp. 99-99
Gabitass RF, Annels NE, Crawshaw J, Pandha HS, Middleton GW (2011)Use of gemcitabine- (Gem) and fluropyrimidine (FP)-based chemotherapy to reduce myeloid-derived suppressor cells (MDSCs) in pancreatic (PC) and esophagogastric cancer (EGC)., In: JOURNAL OF CLINICAL ONCOLOGY29(15) AMER SOC CLINICAL ONCOLOGY
Pulido J, Kottke T, Thompson J, Galivo F, Wongthida P, Diaz RM, Rommelfanger D, Ilett E, Pease L, Pandha H, Harrington K, Selby P, Melcher A, Vile R (2012)Using virally expressed melanoma cDNA libraries to identify tumor-associated antigens that cure melanoma, In: Nature Biotechnology30(4)pp. 337-343
Relph KL, Pandha H, Simpson GR, Melcher A, Harrington K (2016)Cancer immunotherapy via combining oncolytic virotherapy with chemotherapy: recent advances, In: Oncolytic Virotherapy2016(5)pp. 1-13 Dove Medical Press
Coffey M, Thompson B, De-Bono J, Pandha HS, Melcher A, Kaye S, Harrington KJ, Vidal L, Twigger K, White C (2005)Reovirus enhances radiation cytotoxicity in vitro and in vivo., In: CLINICAL CANCER RESEARCH11(24)pp. 9005S-9006S
Khankari NK, Murff HJ, Zeng C, Wen W, Eeles RA, Easton DF, Kote-Jarai Z, Al Olama AA, Benlloch S, Muir K, Giles GG, Wiklund F, Gronberg H, Haiman CA, Schleutker J, Pashayan N, Nordestgaard BG, Travis RC, Donovan JL, Khaw K, Stanford JL, Blot WJ, Thibodeau SN, Maier C, Kibel AS, Park J, Cybulski C, Cannon-Albright L, Brenner H, Kaneva R, Batra J, Teixeira MR, Pandha HS, Zheng W (2016)Polyunsaturated fatty acids and prostate cancer risk: a Mendelian randomization analysis from the PRACTICAL consortium, In: British Journal of Cancer Springer Nature
Pandha H, Rigg A, John J, Lemoine N (2007)Loss of expression of antigen-presenting molecules in human pancreatic cancer and pancreatic cancer cell lines, In: CLINICAL AND EXPERIMENTAL IMMUNOLOGY148(1)pp. 127-135 BLACKWELL PUBLISHING
Michael A, John J, Meyer B, Pandha H (2010)Activation and Genetic Modification of Human Monocyte-Derived Dendritic Cells using Attenuated Salmonella typhimurium, In: THESCIENTIFICWORLDJOURNAL10pp. 393-401 THESCIENTIFICWORLD LTD
Vidal L, Pandha H, Harrington K, Fong P, Shaw H, Barrett M, Leader D, White C, Kaye S, Twigger K, Coffey M, Thompson B, De-Bono J (2005)A phase I study of a wild-type reovirus (Reolysin) given intravenously to patients with advanced malignancies., In: CLINICAL CANCER RESEARCH11(24)pp. 9106S-9107S
Agrawal VK, Copeland KM, Barbachano Y, Rahim A, Seth R, White CL, Hingorani M, Nutting CM, Kelly M, Harris P, Pandha H, Melcher AA, Vile RG, Porter C, Harrington KJ (2009)Microvascular free tissue transfer for gene delivery: in vivo evaluation of different routes of plasmid and adenoviral delivery, In: GENE THERAPY16(1)pp. 78-92 NATURE PUBLISHING GROUP
Michael A, Syrigos K, Pandha H (2009)Prostate cancer chemotherapy in the era of targeted therapy, In: PROSTATE CANCER AND PROSTATIC DISEASES12(1)pp. 13-16 NATURE PUBLISHING GROUP
Hamdan S, Verbeke CS, Fox N, Booth J, Bottley G, Pandha HS, Blair GE (2011)The roles of cell surface attachment molecules and coagulation Factor X in adenovirus 5-mediated gene transfer in pancreatic cancer cells., In: Cancer Gene Ther18(7)pp. 478-488
Dalgleish A, Pandha H (2007)Tumor antigens as surrogate markers and targets for therapy and vaccines, In: Hampton GM, Sikora K (eds.), ADVANCES IN CANCER RESEARCH, VOL 9696pp. 175-190 ELSEVIER ACADEMIC PRESS INC
Errico MC, Felicetti F, Bottero L, Mattia G, Felli N, Petrini M, Bellenghi M, Pandha HS, Morgan R, Care A (2014)THE ABROGATION OF THE HOXB7/PBX2 COMPLEX INDUCES APOPTOSIS IN MELANOMA THROUGH THE MIR-221&222-c-FOS PATHWAY, In: ANTICANCER RESEARCH34(10)pp. 5895-5896 INT INST ANTICANCER RESEARCH
Røder Martin Andreas, Iversen Peter, Brenner Hermann, Cuk Katarina, Holleczek Bernd, Maier Christiane, Luedeke Manuel, Schnoeller Thomas, Kim Jeri, Logothetis Christopher J., John Esther M., Teixeira Manuel R., Paulo Paula, Cardoso Marta, De Ruyck Kim, Neuhausen Susan L., Steele Linda, Ding Yuan Chun, De Meerleer Gert, Ost Piet, Razack Azad, Lim Jasmine, Teo Soo-Hwang, Lin Daniel W., Kulis Tomislav, Newcomb Lisa F., Lessel Davor, Gamulin Marija, Kaneva Radka, Usmani Nawaid, Singhal Sandeep, Slavov Chavdar, Mitev Vanio, Van den Broeck Thomas, Parliament Matthew, Claessens Frank, Joniau Steven, Larkin Samantha, Townsend Paul A., Aukim-Hastie Claire, Dominguez Manuela Gago, Castelao Jose Esteban, Benlloch Sara, Schumacher Fredrick R., Al Olama Ali Amin, Berndt Sonja I., Ahmed Mahbubl, Saunders Edward J., Dadaev Tokhir, Leongamornlert Daniel, van Schaik Ron H. N., Martinez Maria Elena, Roobol Monique J., Jenster Guido, Menegaux Florence, Truong Thérèse, Koudou Yves Akoli, Xu Jianfeng, Khaw Kay-Tee, Brook Mark N., Anokian Ezequiel, Cieza-Borrella Clara, Goh Chee, Sheng Xin, Fachal Laura, Dennis Joe, Tyrer Jonathan, Muir Kenneth, Lophatananon Artitaya, Thibodeau Stephen N., Cannon-Albright Lisa, Pandha Hardev, Michael Agnieszka, McDonnell Shannon K., Schaid Daniel J., Lindstrom Sara, Turman Constance, Ma Jing, Tangen Catherine M., Stevens Victoria L., Gapstur Susan M., Carter Brian D., Goodman Phyllis J., Thompson Ian M., Batra Jyotsna, Chambers Suzanne, Canzian Federico, Hunter David J., Riboli Elio, Siddiq Afshan, Kolonel Laurence N., Le Marchand Loic, Hoover Robert N., Machiela Mitchell J., Cui Zuxi, Kraft Peter, Tilley Wayne, Moya Leire, Clements Judith, Horvath Lisa, Risbridger Gail P., Gronberg Henrik, Aly Markus, Nordström Tobias, Pharoah Paul, Pashayan Nora, Wiklund Fredrik, Amos Christopher I., Conti David V., Easton Douglas F., Chanock Stephen J., Henderson Brian E., Kote-Jarai Zsofia, Haiman Christopher A., Eeles Rosalind A., Auvinen Anssi, Schleutker Johanna, Tammela Teuvo L. J., Sipeky Csilla, Albanes Demetrius, Weinstein Stephanie, Wolk Alicja, Håkansson Niclas, West Catharine M. L., Giovannucci Edward, Dunning Alison M., Burnet Neil, Mucci Lorelei A., Andriole Gerald L., Cussenot Olivier, Cancel-Tassin Géraldine, Koutros Stella, Beane Freeman Laura E., Maehle Lovise, Sorensen Karina Dalsgaard, Orntoft Torben Falck, Borre Michael, Grindedal Eli Marie, Neal David E., Donovan Jenny L., Hamdy Freddie C., Hamilton Robert J., Martin Richard M., Travis Ruth C., Key Tim J., Fleshner Neil E., Finelli Antonio, Ingles Sue Ann, Stern Mariana C., Rosenstein Barry S., Zhang Hong-Wei, Kerns Sarah L., Ostrer Harry, Lu Yong-Jie, Feng Ninghan, Mao Xueying, Guo Xin, Wang Guomin, Sun Zan, Giles Graham G., Kibel Adam S., Southey Melissa C., MacInnis Robert J., FitzGerald Liesel M., Drake Bettina F., Vega Ana, Gómez-Caamaño Antonio, Szulkin Robert, Eklund Martin, Penney Kathryn L., Kogevinas Manolis, Llorca Javier, Castaño-Vinyals Gemma, Stampfer Meir, Park Jong Y., Sellers Thomas A., Lin Hui-Yi, Stanford Janet L., Ostrander Elaine A., Cybulski Cezary, Wokolorczyk Dominika, Lubinski Jan, Geybels Milan S., Nordestgaard Børge G., Nielsen Sune F., Weischer Maren, Bisbjerg Rasmus (2018)Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci, In: Nature Genetics50(7)pp. 928-936 Nature Publishing Group
Pandha HS, Protheroe A, Wylie J, Parker C, Chambers J, Bell S, Munzert G (2008)An open label phase II trial of BI 2536, a novel Plk1 inhibitor, in patients with metastatic hormone refractory prostate cancer (HRPC), In: JOURNAL OF CLINICAL ONCOLOGY26(15) AMER SOC CLINICAL ONCOLOGY
Hingorani M, White CL, Zaidi S, Merron A, Peerlinck I, Gore ME, Nutting CM, Pandha HS, Melcher AA, Vile RG, Vassaux G, Harrington KJ (2008)Radiation-mediated up-regulation of gene expression from replication-defective adenoviral vectors: Implications for sodium iodide symporter gene therapy, In: CLINICAL CANCER RESEARCH14(15)pp. 4915-4924 AMER ASSOC CANCER RESEARCH
Morgan R, Gray S, Gillett C, Tabi Z, Launchbury F, Spicer J, Harrington K, Pandha HS (2014)HOX TRANSCRIPTION FACTORS ARE POTENTIAL TARGETS AND MARKERS IN MALIGNANT MESOTHELIOMA, In: ANTICANCER RESEARCH34(10)pp. 6069-6071 INT INST ANTICANCER RESEARCH
Alamara C, Karapanagiotou EM, Tourkantonis I, Xyla V, Maurer CC, Lykourinas M, Pandha H, Syrigos KN (2008)Renal oncocytoma: a case report and short review of the literature., In: Eur J Intern Med19(7)pp. e67-e69
Lunt C, Barber N, Montgomery A, Kalsi V, Parker T, Michael A, Pandha H, Hindley R (2010)CYTOREDUCTIVE NEPHRECTOMY IN THE TYROKINASE INHIBITOR ERA, In: J ENDOUROL24pp. A303-A303 MARY ANN LIEBERT INC
Morgan R, Simpson G, Gray S, Gillett C, Tabi Z, Spicer J, Harrington KJ, Pandha HS (2016)HOX transcription factors are potential targets and markers in malignant mesothelioma, In: BMC CANCER16ARTN 85 BIOMED CENTRAL LTD
Ross ADM, Cook MG, Chong H, Hossain M, Pandha HS, Bennett DC (2013)Senescence evasion in melanoma progression: uncoupling of DNA-damage signaling from p53 activation and p21 expression, In: PIGMENT CELL & MELANOMA RESEARCH26(2) WILEY-BLACKWELL
Morgan R, Boxall A, Bhatt A, Bailey M, Hindley R, Langley S, Whitaker HC, Neal DE, Ismail M, Whitaker H, Annels N, Michael A, Pandha H (2011)Engrailed-2 (EN2): A Tumor Specific Urinary Biomarker for the Early Diagnosis of Prostate Cancer, In: CLINICAL CANCER RESEARCH17(5)pp. 1090-1098 AMER ASSOC CANCER RESEARCH
Quatan N, Meyer B, Bailey M, Pandha H (2006)Persistently high levels of immunosuppressive cytokines in patients after radical prostatectomy, In: PROSTATE CANCER AND PROSTATIC DISEASES9(4)pp. 420-425 NATURE PUBLISHING GROUP
Morgan Richard, Bryan RT, Javed S, Launchbury F, Zeegers MP, Cheng KK, James ND, Wallace DM, Hurst CD, Ward DG, Knowles MA, Pandha Hardev (2013)Expression of Engrailed-2 (EN2) protein in bladder cancer and its potential utility as a urinary diagnostic biomarker., In: Eur J Cancer Elsevier
Enting D, Lannitto ML, Pandha HS, Eberi M, Chowdhury S, Hayday AC (2014)Effects of concomitant therapies on gamma delta T-cell responses to zoledronate in patients with advanced prostate cancer, In: JOURNAL OF CLINICAL ONCOLOGY32(15)
Chowdhury S, Pandha H (2006)Targeting renal cell carcinoma, In: CLINICAL ONCOLOGY18(7)pp. 511-512 ELSEVIER SCIENCE LONDON
Kelly Z, Pandha H, Madhuri K, Morgan R, Michael A (2012)HOX GENE EXPRESSION IN OVARIAN CANCER, In: ANNALS OF ONCOLOGY23pp. 68-68
Zaidi S, Blanchard M, Shim K, Ilett E, Kottke T, Thompson J, Celis E, Harrington K, Pandha H, Selby P, Melcher A, Vile R (2014)Acquisition of Mutated BRAF Is as a Major Effector of Melanoma Recurrence Which Can Be Targeted By Immuno- or Chemo-Therapy, In: MOLECULAR THERAPY22pp. S245-S245
Roulstone V, Khan K, Pandha HS, Rudman S, Coffey M, Gill GM, Melcher AA, Vile R, Harrington KJ, de Bono J, Spicer J (2015)Phase I Trial of Cyclophosphamide as an Immune Modulator for Optimizing Oncolytic Reovirus Delivery to Solid Tumors, In: CLINICAL CANCER RESEARCH21(6)pp. 1305-1312 AMER ASSOC CANCER RESEARCH
Michael A, Relph K, Pandha H (2010)Emergence of potential biomarkers of response to anti-angiogenic anti-tumour agents., In: International Journal of Cancer127(6)pp. 1251-1258 Wiley-Blackwell
Donnelly OG, Errington-Mais F, Steele L, Hadac E, Jennings V, Scott K, Peach H, Phillips RM, Bond J, Pandha H, Harrington K, Vile R, Russell S, Selby P, Melcher AA (2011)Measles virus causes immunogenic cell death in human melanoma., In: Gene Ther
Derhovanessian E, Adams V, Haehnel K, Groeger A, Pandha H, Ward S, Pawelec G (2009)Pretreatment frequency of circulating IL-17(+)CD4(+) T-cells, but not Tregs, correlates with clinical response to whole-cell vaccination in prostate cancer patients, In: INTERNATIONAL JOURNAL OF CANCER125(6)pp. 1372-1379 WILEY-BLACKWELL
Ismail M, Bokaee S, Morgan R, Davies J, Harrington KJ, Pandha H (2009)Inhibition of the aquaporin 3 water channel increases the sensitivity of prostate cancer cells to cryotherapy (vol 100, pg 1889, 2009), In: BRITISH JOURNAL OF CANCER101(3)pp. 549-549 NATURE PUBLISHING GROUP
Pandha H, Birchall L, Meyer B, Wilson N, Relph K, Anderson C, Harrington K (2006)Antitumor effects of aminobisphosphonates on renal cell carcinoma cell lines, In: JOURNAL OF UROLOGY176(5)pp. 2255-2261 ELSEVIER SCIENCE INC
Comins C, Heinemann L, Harrington K, Melcher A, De Bono J, Pandha H (2008)Reovirus: Viral therapy for cancer 'as nature intended', In: CLINICAL ONCOLOGY20(7)pp. 548-554 ELSEVIER SCIENCE LONDON
Michael A, Kelly ZL, Moller-Levet CS, Pandha H, Morgan R (2014)HOX GENE EXPRESSION IN OVARIAN CANCER, In: ANTICANCER RESEARCH34(10)pp. 6058-6059 INT INST ANTICANCER RESEARCH
Kottke T, Hall G, Pulido J, Diaz RM, Thompson J, Chong H, Selby P, Coffey M, Pandha H, Chester J, Melcher A, Harrington K, Vile R (2010)Antiangiogenic cancer therapy combined with oncolytic virotherapy leads to regression of established tumors in mice, In: JOURNAL OF CLINICAL INVESTIGATION120(5)pp. 1551-1560 AMER SOC CLINICAL INVESTIGATION INC
Michael Agnieszka, Relph Kate, Annels Nicola, Pandha Hardev (2014)Prostate cancer vaccines., In: Expert Review of Vaccines12(3)pp. 253-262 Taylor & Francis
Comins C, Spicer J, Protheroe A, Roulstone V, Twigger K, White CM, Vile R, Melcher A, Coffey MC, Mettinger KL, Nuovo G, Cohn DE, Phelps M, Harrington KJ, Pandha HS (2010)REO-10: A Phase I Study of Intravenous Reovirus and Docetaxel in Patients with Advanced Cancer, In: CLINICAL CANCER RESEARCH16(22)pp. 5564-5572 AMER ASSOC CANCER RESEARCH
Müller Louise M. E., Holmes Matthew, Michael Joanne L., Scott Gina B., West Emma J., Scott Karen J., Parrish Christopher, Halliwell Kathryn, Stäble Sina, Jennings Victoria A., Cullen Matthew, McConnell Stewart, Langton Catherine, Tidswell Emma L., Shafren Darren, Samson Adel, Kelly Richard J., Harrington Kevin J., Pandha Hardev, Ralph Christy, Cook Gordon, Melcher Alan A., Errington-Mais Fiona (2019)Plasmacytoid dendritic cells orchestrate innate and adaptive anti-tumor immunity induced by oncolytic coxsackievirus A21, In: Journal for ImmunoTherapy of Cancer7164pp. 1-16 BMC
Kottke T, Errington F, Pulido J, Galivo F, Thompson J, Wongthida P, Diaz RM, Chong H, Ilett E, Chester J, Pandha H, Harrington K, Selby P, Melcher A, Vile R (2011)Broad antigenic coverage induced by vaccination with virus-based cDNA libraries cures established tumors., In: Nat Med17(7)pp. 854-859
Harrington KJ, Melcher A, Vassaux G, Pandha HS, Vile RG (2008)Exploiting synergies between radiation and oncolytic viruses, In: CURRENT OPINION IN MOLECULAR THERAPEUTICS10(4)pp. 362-370 THOMSON SCIENTIFIC
Balls G, Quatan N, Michael A, Lancashire L, Adams V, Hoffman B, Pfirschke C, Russell N, Whelan M, Pandha H (2007)Immunological response patterns correlate with clinical outcome after allogeneic vaccination in hormone resistant prostate cancer metastatic to bone, In: JOURNAL OF IMMUNOTHERAPY30(8)pp. 891-891
Qiao J, Wang H, Kottke T, White C, Twigger K, Diaz RM, Thompson J, Selby P, de Bono J, Melcher A, Pandha H, Coffey M, Vile R, Harrington K (2008)Cyclophosphamide facilitates antitumor efficacy against subcutaneous tumors following intravenous delivery of reovirus, In: CLINICAL CANCER RESEARCH14(1)pp. 259-269 AMER ASSOC CANCER RESEARCH
Ismail M, Ahmed S, Laing R, Nigam R, Langley S, Pandha H, Davies J (2007)Antibody immunity to prostate cancer specific antigen in the serum of patients having cryotherapy or brachytherapy treatment compared to healthy volunteers, In: BJU INTERNATIONAL99pp. 47-48
Plowright L, Harrington K, Pandha HS, Morgan R HOX transcription factors are potential therapeutic targets in non-small cell lung cancer, In: British Journal of Cancer Nature Publishing Group
Harris D, Vidal L, Melcher A, Newbold K, Anthony A, Karavasilis V, Agarwal R, White C, Twigger K, Coffey M, Mettinger K, Thompson B, Pandha H, De-Bono J, Harrington K (2007)A Phase I study to evaluate the feasibility, safety and biological effects of intratumoural administration of wild-type Reovirus (REOLYSIN (R)) in combination with radiation in patients with advanced malignancies., In: MOLECULAR CANCER THERAPEUTICS6(12)pp. 3458S-3458S AMER ASSOC CANCER RESEARCH
Relph KL, Harrington KJ, Pandha H (2005)Adenoviral strategies for the gene therapy of cancer, In: SEMINARS IN ONCOLOGY32(6)pp. 573-582 W B SAUNDERS CO
McGrath SE, Michael A, Morgan R, Pandha H (2013)EN2: a novel prostate cancer biomarker., In: Biomark Med7(6)pp. 893-901
Havranek EG, Labarthe M-C, Ward S, Anderson CJ, Whelan MA, Pandha H (2008)A novel murine model of allogeneic vaccination against renal cancer, In: BJU INTERNATIONAL101(9)pp. 1165-1169 BLACKWELL PUBLISHING
Yap TA, Brunetto A, Pandha H, Harrington K, de Bono JS (2008)Reovirus therapy in cancer: has the orphan virus found a home?, In: EXPERT OPINION ON INVESTIGATIONAL DRUGS17(12)pp. 1925-1935 INFORMA HEALTHCARE
Heinemann L, Relph KL, Simpson GR, Boxall A, Kottke T, Vile R, Melcher A, Prestwich R, Harrington KJ, Morgan R, Pandha HS (2011)Synergistic effects of oncolytic reovirus and docetaxel chemotherapy in prostate cancer., In: BMC Cancer11pp. 221-? Biomed Central
Daniels TR, Neacato II, Rodriguez JA, Pandha HS, Morgan R, Penichet ML (2014)TARGETING THE HOX TRANSCRIPTION FACTORS AND CD71 IN MULTIPLE MYELOMA, In: ANTICANCER RESEARCH34(10)pp. 6107-6108 INT INST ANTICANCER RESEARCH
Haycock P, Yu OH, Richards JB, Eeles R, Easton D, Kote-Jarai Z, Amin Al Olama A, Benlloch S, Muir K, Giles GG, MacInnis RJ, Wiklund F, Gronberg H, Haiman CA, Schleutker J, Nordestgaard BG, Travis RC, Neal D, Pashayan N, Thibodeau S, Khaw KT, Stanford JL, Blot WJ, Maier C, Kibel AS, Cybulski C, Cannon-Albright L, Brenner H, Park J, Micheal A, Kaneva R, Batra J, Teixeira MR, Pandha H, Smith GD, Lewis SJ, Martin RM, Perks CM, Bull CJ, Bonilla C, Holly JM, Davies N (2016)Blood lipids and prostate cancer: a Mendelian randomization analysis., In: Cancer medicine5(6)pp. 1125-1136
Vidal L, Pandha H, Spicer J, Harrington KJ, Allen S, Kaye S, Leader D, Coffey M, Thompson B, De-Bono J (2006)A phase I study of reolysin given intravenously to patients with advanced malignancies., In: JOURNAL OF CLINICAL ONCOLOGY24(18)pp. 136S-136S
Simpson GR, Horvath A, Harrington K, Coffin RS, Pandha H (2008)Combination of a fusogenic glycoprotein, pro-drug activation and oncolytic HSV as an intravesical therapy for superficial bladder cancer, In: EJC SUPPLEMENTS6(12)pp. 97-98
Papaetis GS, Karapanagiotou LM, Pandha H, Syrigos KN (2008)Targeted therapy for advanced renal cell cancer: Cytokines and beyond, In: CURRENT PHARMACEUTICAL DESIGN14(22)pp. 2229-2251 BENTHAM SCIENCE PUBL LTD
Morgan R, Fairfax B, Pandha HS (2006)Calcium insensitivity of FA-6, a cell line derived from a pancreatic cancer associated with humoral hypercalcemia, is mediated by the significantly reduced expression of the Calcium Sensitive Receptor transduction component p38 MAPK, In: MOLECULAR CANCER5ARTN 5pp. ?-? BIOMED CENTRAL LTD
Hingorani M, Spitzweg C, Vassaux G, Newbold K, Melcher A, Pandha H, Vile R, Harrington K (2010)The Biology of the Sodium Iodide Symporter and its Potential for Targeted Gene Delivery, In: CURR CANCER DRUG TAR10(2)pp. 242-267 BENTHAM SCIENCE PUBL LTD
Pandha H, Melcher A, Harrington K, Vile R (2009)Oncolytic Viruses: Time to Compare, Contrast, and Combine?, In: MOLECULAR THERAPY17(6)pp. 934-935 NATURE PUBLISHING GROUP
Horvath A, Simpson GR, Coffin RS, Mostafid AH, Pandha H (2011)Update on a novel intravesical therapy for non muscle invasive bladder cancer: Combination of a fusogenic glycoprotein, pro-drug activation and oncolytic herpes simplex virus, In: BRITISH JOURNAL OF SURGERY98(6)pp. E2-E2
Spicer J, Plunkett T, Somaiah N, Chan S, Kendall A, Bolunwu N, Pandha H (2005)Phase II study of oral capecitabine in patients with hormone-refractory prostate cancer, In: PROSTATE CANCER AND PROSTATIC DISEASES8(4)pp. 364-368 NATURE PUBLISHING GROUP
Pandha HS, Harrington KJ, Vile RG (2008)Poxviruses as immunomodulatory cancer therapeutics., In: Viral Therapy of Cancer
Pencavel T, Seth R, Hayes A, Melcher A, Pandha H, Vile R, Harrington KJ (2010)Locoregional intravascular viral therapy of cancer: precision guidance for Paris's arrow?, In: GENE THERAPY17(8)pp. 949-960 NATURE PUBLISHING GROUP
Koropouli E, Manolopoulus L, Pandha H, Syrigos KN (2009)The biological role of mTOR in the pathogenesis of solid tumors: An overview, In: Current Enzyme Inhibition5(1)pp. 51-65
Saunders EJ, Dadaev T, Leongamornlert DA, Olama AA, Benlloch S, Giles GG, Wiklund F, Grönberg H, Haiman CA, Schleutker J, Nordestgaard BG, Khaw KT, Travis RC, Neal D, Pasayan N, Stanford JL, Blot WJ, Thibodeau SN, Maier C, Kibel AS, Cybulski C, Kaneva R, Cannon-Albright L, Brenner H, Park JY, Batra J, Teixeira MR, Pandha H, Govindasami K, Muir K, Genetic Prostate Cancer Study Collaborators UK, Eeles RA, ProtecT Study Collaborators UK, Consortium PRACTICAL, Easton DF, Kote-Jarai Z (2016)Gene and pathway level analyses of germline DNA-repair gene variants and prostate cancer susceptibility using the iCOGS-genotyping array., In: British Journal of Cancer114pp. 945-952 Cancer Research UK
George D, Martini J-F, Staehler M, Motzer R, Magheli A, Escudier B, Gerletti P, Li S, Pantuck A, Casey M, Laguerre B, Pandha Hardev, Patel A, Lechuga M, Ravaud A (2018)Immune biomarkers predictive for disease-free survival with adjuvant sunitinib in high-risk locoregional renal cell carcinoma: from randomized phase III S-TRAC study, In: Clinical Cancer Research American Association for Cancer Research
Taylor AE, Martin RM, Kote-Jarai Z, Al Olama AA, Benlloch S, Muir K, Giles GG, Wiklund F, Gronberg H, Haiman CA, Schleutker J, Pashayan N, Nordestgaard BG, Travis RC, Neal D, Khaw KT, Blott W, Thibodeau S, Maier C, Kibel AS, Cybulski C, Kaneva R, Cannon‐Albright L, Brenner H, Park J, Batra J, Teixeira MR, Pandha HS, PRACTICAL Consortium ., Donovan J, Munafo MR (2016)Investigating the possible causal role of coffee consumption with prostate cancer risk and progression using Mendelian randomization analysis, In: International Journal of Cancer
Yap TA, Vidal L, Pandha H, Spicer J, Digue L, Coffey M, Thompson B, Kaye SB, Harrington KJ, De-Bono JS (2006)A phase I study of wild-type reovirus, which selectively replicates in cells expressing activated Ras, administered intravenously to patients with advanced cancer, In: EJC SUPPLEMENTS4(12)pp. 108-108 PERGAMON-ELSEVIER SCIENCE LTD
Prestwich RJ, Ilett EJ, Errington F, Diaz RM, Steele LP, Kottke T, Thompson J, Galivo F, Harrington KJ, Pandha HS, Selby PJ, Vile RG, Melcher AA (2009)Immune-Mediated Antitumor Activity of Reovirus Is Required for Therapy and Is Independent of Direct Viral Oncolysis and Replication, In: CLINICAL CANCER RESEARCH15(13)pp. 4374-4381 AMER ASSOC CANCER RESEARCH
White CL, Twigger KR, Vidal L, De Bono JS, Coffey M, Heinemann L, Morgan R, Merrick A, Errington F, Vile RG, Melcher AA, Pandha HS, Harrington KJ (2008)Characterization of the adaptive and innate immune response to intravenous oncolytic reovirus (Dearing type 3) during a phase I clinical trial, In: GENE THERAPY15(12)pp. 911-920 NATURE PUBLISHING GROUP
Roulstone Victoria, Seth Rohit, Halle Martin, Somaiah Navita, Boult Jessica K. R., Robinson Simon P., Pandha Hardev, Vile Richard G., Melcher Alan A., Harris Paul A., Harrington Kevin J., Kyula Joan N., Khan Aadil A., Paget James T., McLaughlin Martin, Wilkinson Michelle J., Pencavel Timothy, Mansfield David (2018)Genetically modified lentiviruses that preserve microvascular function protect against late radiation damage in normal tissues, In: Science Translational Medicine10(425) American Association for the Advancement of Science
Annels Nicola, Arif Mehreen, Simpson Guy, Denyer Mick, Moller-Levet Carla, Mansfield David, Butler Rachel, Shafren Darren, Au Gough, Knowles Margaret, Harrington Kevin, Vile Richard, Melcher Alan, Pandha Hardev (2018)Oncolytic Immunotherapy for Bladder Cancer Using Coxsackie A21 Virus, In: Molecular Therapy - Oncolytics9pp. 1-12 Elsevier
Prestwich RJ, Scott KJ, Brown J, Harnden P, Whelan P, Cartledge J, O'Donnell D, Pandha HS, Selby PJ, Banks RE, Merrick AE, Melcher AA (2009)The feasibility of establishing a programme of adjuvant autologous vaccination for renal cell carcinoma, In: BJU INTERNATIONAL103(6)pp. 740-746 WILEY-BLACKWELL PUBLISHING, INC
Hingorani M, White CL, Merron A, Peerlinck I, Gore ME, Slade A, Scott SD, Nutting CM, Pandha HS, Melcher AA, Vile RG, Vassaux G, Harrington KJ (2008)Inhibition of Repair of Radiation-Induced DNA Damage Enhances Gene Expression from Replication-Defective Adenoviral Vectors, In: CANCER RESEARCH68(23)pp. 9771-9778 AMER ASSOC CANCER RESEARCH
Hall K, Scott KJ, Pandha H, Rose A, Desborough M, Harrington K, Parrish C, Vile R, Coffey M, Bowen D, Errington-Mais F, Melcher AA (2012)Reovirus-mediated cytotoxicity and enhancement of innate immune responses against acute myeloid leukemia., In: Biores Open Access1(1)pp. 3-15
Ismail M, Morgan R, Davies J, Pandha H (2009)Inhibition of the aquaporin water channels (AQPs) increases the sensitivity of DU145 cells to cryotherapy, In: BJU INTERNATIONAL103pp. 21-21
Prestwich RJ, Harrington KJ, Pandha HS, Vile RG, Melcher AA, Errington F (2008)Oncolytic viruses: a novel form of immunotherapy, In: EXPERT REVIEW OF ANTICANCER THERAPY8(10)pp. 1581-1588 EXPERT REVIEWS
Eatock M, Valle J, Smith D, Wadsley J, Cunningham D, Pandha H, Neoptolemos JP, Billingham L, Middleton G, Annels NE, Shaw VE, Gabitass RF, Corrie P (2013)The effects of gemcitabine and capecitabine combination chemotherapy and of low-dose adjuvant GM-CSF on the levels of myeloid-derived suppressor cells in patients with advanced pancreatic cancer., In: Cancer Immunol Immunother
Morgan R, Boxall A, Harrington KJ, Simpson GR, Michael A, Pandha HS (2014)Targeting HOX transcription factors in prostate cancer, In: BMC UROLOGY14ARTN 1pp. ?-? BIOMED CENTRAL LTD
Alharbi RA, Pandha HS, Morgan R, Pettengell R (2013)The role of HOX genes in normal hematopoiesis and acute leukemia, In: Leukemia27(5)pp. 1000-1008
Ilett E, Kottke T, Donnelly O, Thompson J, Willmon C, Diaz R, Zaidi S, Coffey M, Selby P, Harrington K, Pandha H, Melcher A, Vile R (2014)Cytokine Conditioning Enhances Systemic Delivery and Therapy of an Oncolytic Virus, In: MOLECULAR THERAPY22(10)pp. 1851-1863 NATURE PUBLISHING GROUP
Karapanagiotou EM, Roulstone V, Twigger K, Ball M, Tanay M, Nutting C, Newbold K, Gore ME, Larkin J, Syrigos KN, Coffey M, Thompson B, Mettinger K, Vile RG, Pandha HS, Hall GD, Melcher AA, Chester J, Harrington KJ (2012)Phase I/II Trial of Carboplatin and Paclitaxel Chemotherapy in Combination with Intravenous Oncolytic Reovirus in Patients with Advanced Malignancies, In: CLINICAL CANCER RESEARCH18(7)pp. 2080-2089 AMER ASSOC CANCER RESEARCH
Roulstone V, Twigger K, Zaidi S, Pencavel T, Kyula JN, White C, McLaughlin M, Seth R, Karapanagiotou EM, Mansfield D, Coffey M, Nuovo G, Vile RG, Pandha HS, Melcher AA, Harrington KJ (2012)Synergistic cytotoxicity of oncolytic reovirus in combination with cisplatin-paclitaxel doublet chemotherapy., In: Gene Ther
Bonilla C, Lewis SJ, Martin RM, Donovan JL, Hamdy FC, Neal DE, Eeles R, Easton D, Kote-Jarai Z, Al Olama AA, Benlloch S, Muir K, Giles GG, Wiklund F, Gronberg H, Haiman CA, Schleutker J, Nordestgaard BG, Stanford JL, Travis RC, Pashayan N, Khaw KT, Blot WJ, Thibodeau S, Maier C, Kibel AS, Cybulski C, Cannon-Albright L, Batra J, Brenner H, Park J, Kaneva R, Teixeira MR, Pandha H, Lathrop M, Davey Smith G, Consortium PRACTICAL (2016)Pubertal development and prostate cancer risk: Mendelian randomization study in a population-based cohort., In: BMC Medicine14(1)pp. 66-76 BioMed Central
Simpson Guy, Michael Agnieszka, Pandha Hardev, Harrington KJ, Gillett C, Boxall A, Morgan Richard (2012)Targeting the HOX/PBX dimer in breast cancer, In: Breast Cancer Research and Treatment136(2)pp. 389-398 Springer Verlag
Simpson GR, Horvath A, Annels NE, Pencavel T, Metcalf S, Seth R, Peschard P, Price T, Coffin RS, Mostafid H, Melcher AA, Harrington KJ, Pandha HS (2012)Combination of a fusogenic glycoprotein, pro-drug activation and oncolytic HSV as an intravesical therapy for superficial bladder cancer, In: BRITISH JOURNAL OF CANCER106(3)pp. 496-507
McGrath Sophie Elena, Annels Nicola, Madhuri Thumuluru K, Taylor Anil, Butler-Manuel Simon A., Morgan Richard, Pandha Hardev, Michael Agnieszka (2018)A novel Biomarker in epithelial ovarian cancer, In: BMC Cancer18943 BMC
Adair RA, Scott KJ, Fraser S, Errington-Mais F, Pandha H, Coffey M, Selby P, Cook GP, Vile R, Harrington KJ, Toogood G, Melcher AA (2012)Cytotoxic and immune-mediated killing of human colorectal cancer by reovirus-loaded blood and liver mononuclear cells., In: Int J Cancer
Ilett EJ, Prestwich RJ, Kottke T, Errington F, Thompson JM, Harrington KJ, Pandha HS, Coffey M, Selby PJ, Vile RG, Melcher AA (2009)Dendritic cells and T cells deliver oncolytic reovirus for tumour killing despite pre-existing anti-viral immunity, In: GENE THERAPY16(5)pp. 689-699 NATURE PUBLISHING GROUP
Morgan R, Boxall A, Harrington KJ, Simpson GR, Gillett C, Michael A, Pandha HS (2012)Targeting the HOX/PBX dimer in breast cancer., In: Breast Cancer Res Treat136(2)pp. 389-398 Springer
Yap TA, White CL, Twigger K, Vile RG, Melcher A, Coffey M, Harrington KJ, DeBono JS, Vidal L, Pandha HS (2008)A Phase I Study of Intravenous Oncolytic Reovirus Type 3 Dearing in Patients with Advanced Cancer, In: CLINICAL CANCER RESEARCH14(21)pp. 7127-7137 AMER ASSOC CANCER RESEARCH
Prestwich RJ, Errington F, Steele LP, Ilett EJ, Morgan RSM, Harrington KJ, Pandha HS, Selby PJ, Vile RG, Melcher AA (2009)Reciprocal Human Dendritic Cell-Natural Killer Cell Interactions Induce Antitumor Activity Following Tumor Cell Infection by Oncolytic Reovirus, In: JOURNAL OF IMMUNOLOGY183(7)pp. 4312-4321 AMER ASSOC IMMUNOLOGISTS
Gogalic S, Sauer U, Doppler S, Heinzel A, Perco P, Lukas A, Simpson Guy, Pandha Hardev, Horvath A, Preininger C (2017)Validation of a protein panel for the non-invasive detection of recurrent non-muscle invasive bladder cancer, In: Biomarkers22(7)pp. 674-681 Taylor & Francis
Lophatananon Artitaya, Stewart-Brown Sarah, Kote-Jarai Zsofia, Olama Ali Amin Al, Garcia Sara Benlloch, Neal David E, Hamdy Freddie C, Donovan Jenny L, Giles Graham G, Fitzgerald Liesel M, Southey Melissa C, Pharoah Paul, Pashayan Nora, Gronberg Henrik, Wiklund Fredrik, Aly Markus, Stanford Janet L, Brenner Hermann, Lin Hui-Yi, Dieffenbach Aida K, Arndt Volker, Park Jong Y, Sellers Thomas, Slavov Chavdar, Kaneva Radka, Mitev Vanio, Batra Jyotsna, Spurdle Amanda, Wiklund Fredrik, Clements Judith A, Schleutker Johanna, Nordestgaard BØrge G, Travis Ruth C, Haiman Christopher A, Thibodeau Stephen N, Maier Christiane, Walther Vogel, Cannon-Albright Lisa, Blot William J, Kibel Adam S, Cybulski Cezary, Pandha Hardev, Teixeira Manuel R, Cook Margaret, Govindasami Koveela, Guy Michelle, Morgan Angela, Leongamornlert Daniel, Sawyer Emma J, Wilkinson Rosemary, Fisher Cyril, Saunders Edward J, Tymrakiewicz Malgorzata, Livni Naomi, Hazel Steve, Dadaev Tokhir, Marsden Gemma, Cox Angela, George Anne, Lane Athene, Davis Michael, Brown Paul, Pedersen John, Hopper John L, Johansson Jan-Erik, Karlsson Ami, Cavalli-Bjoerkman Carin, Adolfson Jan, Broms Michael, Stattin Paer, Kolb Suzanne, Stegmaier Christa, Zachariah Babu, Park Hyun, Radlein Selina, Haley James, Pow-Sang Julio, Rincon Maria, Vlahova Aleksandrina, Mitkova Atanaska, Kachakova Darina, Popov Elenko, Christova Svetlana, Dikov Tihomir, Malone Greg, Eckert Allison, Collins Angus, Wood Glenn, Alexander Kimberly, Kerr Kris, Kedda Mary-Anne, Srinivasan Srilakshmi, Turner Megan, Saunders Pamela, Heathcote Peter, Omara Tracy, Yeadon Trina, Lose Felicity, Eeles Rosalind A, Easton Douglas, Muir Kenneth (2017)Height, selected genetic markers and prostate cancer risk: results from the PRACTICAL consortium, In: British Journal of Cancer117(5)pp. 734-743 Cancer Research UK / Nature Publishing Group
Pandha H, Sorensen KD, Orntoft TF, Langley S, Hoyer S, Borre M, Morgan R (2012)Urinary engrailed-2 (EN2) levels predict tumour volume in men undergoing radical prostatectomy for prostate cancer., In: BJU Int110(6 Pt B)pp. E287-E292 Wiley-Blackwell
Harrington KJ, Vile RG, Melcher A, Chester J, Pandha HS (2010)Clinical trials with oncolytic reovirus: Moving beyond phase I into combinations with standard therapeutics, In: CYTOKINE & GROWTH FACTOR REVIEWS21(2-3)pp. 91-98 ELSEVIER SCI LTD
Prestwich RJ, Errington F, Diaz RM, Pandha HS, Harrington KJ, Melcher AA, Vile RG (2009)The Case of Oncolytic Viruses Versus the Immune System: Waiting on the Judgment of Solomon, In: HUMAN GENE THERAPY20(10)pp. 1119-1132 MARY ANN LIEBERT INC
Brunner C, Davies NM, Martin RM, Eeles R, Easton D, Kote-Jarai Z, Al Olama AA, Benlloch S, Muir K, Giles G, Wiklund F, Gronberg H, Haiman CA, Schleutker J, Nordestgaard BG, Travis RC, Neal D, Donovan J, Hamdy FC, Pashayan N, Thibodeau S, Khaw KT, Stanford JL, Blot WJ, Maier C, Kibel AS, Cybulski C, Cannon-Albright L, Brenner H, Teixeira MR, Park J, Kaneva R, Batra J, Pandha HS, PRACTICAL Consortium L, Zuccolo (2016)Alcohol Consumption and Prostate Cancer Incidence and Progression: a Mendelian Randomization Study, In: International Journal of Cancer
Tuan J, Pandha H, Corbishley C, Khoo V (2012)Basaloid carcinoma of the prostate: A literature review with case report, In: Indian Journal of Urology28(3)pp. 322-324
Harrington KJ, Karapanagiotou EM, Roulstone V, Twigger KR, White CL, Vidal L, Beirne D, Prestwich R, Newbold K, Ahmed M, Thway K, Nutting CM, Coffey M, Harris D, Vile RG, Pandha HS, DeBono JS, Melcher AA (2010)Two-Stage Phase I Dose-Escalation Study of Intratumoral Reovirus Type 3 Dearing and Palliative Radiotherapy in Patients with Advanced Cancers, In: CLINICAL CANCER RESEARCH16(11)pp. 3067-3077 AMER ASSOC CANCER RESEARCH
Boxall A, Middleton G, Bagwan I, Pandha H, Morgan R, Gray S, Metcalf S (2013)The chorio-allantoicmembrane (CAM) model for testing HOX gene antagonism in pancreatic cancer, In: CANCER RESEARCH73(8)
Anderson C, Relph K, Syrigos KN, Pandha H, Michael A, Politi E, Havranek E, Corbishley C, Karapanagiotou L (2007)Prognostic significance of erythropoietin expression in human renal cell carcinoma, In: BJU INTERNATIONAL100(2)pp. 291-294 BLACKWELL PUBLISHING
Gray S, Pandha HS, Michael A, Middleton G, Morgan R (2011)HOX genes in pancreatic development and cancer., In: JOP12(3)pp. 216-219
Kottke T, Boisgerault N, Diaz RM, Donnelly O, Melcher A, Rommelfanger-Konkol D, Pulido J, Thompson J, Mukhopadhyay D, Kaspar R, Coffey M, Pandha H, Harrington K, Selby P, Vile R (2013)Detecting and targeting tumor relapse by its resistance to innate effectors at early recurrence, In: NATURE MEDICINE19(12)pp. 1625-1631 NATURE PUBLISHING GROUP
Hingorani M, White CL, Zaidi S, Pandha HS, Melcher AA, Bhide SA, Nutting CM, Syrigos KN, Vile RG, Vassaux G, Harrington KJ (2010)Therapeutic Effect of Sodium Iodide Symporter Gene Therapy Combined With External Beam Radiotherapy and Targeted Drugs That Inhibit DNA Repair, In: MOLECULAR THERAPY18(9)pp. 1599-1605 NATURE PUBLISHING GROUP
Michael A, Coward J, Brown A, Barber N, Pandha H (2015)The Tolerability of Sunitinib in Elderly Patients with Metastatic Renal Cancer, In: CLINICAL ONCOLOGY27(6)pp. 371-372 ELSEVIER SCIENCE LONDON
Rudman SM, Comins C, Mukherji D, Coffey M, Mettinger K, Protheroe A, Harrington KJ, Pandha H, Spicer JF (2009)Results of a phase I study to evaluate the feasibility, safety, and biological effects of intravenous administration of wild-type reovirus with docetaxel to patients with advanced malignancies, In: JOURNAL OF CLINICAL ONCOLOGY27(15)
Coward JIG, Larbi ED, Pandha H, Michael A (2011)The effect of age on first-line sunitinib treatment in patients with renal cell carcinoma (RCC)., In: J Clin Oncol 29: 2011 (suppl; abstr e15096)
Harris PA, Harrington KJ, Seth R, Khan AA, Pencavel TD, Wilkinson MJ, Kyula JN, Simpson G, Pandha H, Melcher A, Vile R (2015)Adenovirally Delivered Enzyme Prodrug Therapy with Herpes Simplex Virus-Thymidine Kinase in Composite Tissue Free Flaps Shows Therapeutic Efficacy in Rat Models of Glioma, In: PLASTIC AND RECONSTRUCTIVE SURGERY135(2)pp. 475-487 LIPPINCOTT WILLIAMS & WILKINS
Ismail M, Morgan R, Harrington K, Davies J, Pandha H (2010)Immunoregulatory effects of freeze injured whole tumour cells on human dendritic cells using an in vitro cryotherapy model, In: CRYOBIOLOGY61(3)pp. 268-274 ACADEMIC PRESS INC ELSEVIER SCIENCE
Alonso-Camino V, Rajani K, Kottke T, Rommelfanger-Konkol D, Zaidi S, Thompson J, Pulido J, Ilett L, Selby P, Pandha H, Melcher A, Harrington K, Diaz R, Vile R (2014)The Profile of Tumor Antigens Which Can Be Targeted By Immunotherapy Depends Upon the Tumor's Anatomical Site, In: MOLECULAR THERAPY22pp. S200-S200
Karapanagiotou E, Pandha H, Hall G, Chester J, Melcher A, De Bono J, Gore M, Nutting C, Harrington K (2008)Phase I Trial of Oncolytic Reovirus (Reolysin) in Combination With Carboplatin/Paclitaxel in Patients With Advanced Solid Cancers, In: JOURNAL OF IMMUNOTHERAPY31(9)pp. 952-952
Michael A, Plowright L, Boxall A, Bhatt A, Di Palma S, Parker C, Pandha H (2010)Evaluation of EN2 as a urine-based biomarker for prostate cancer., In: J Clin Oncol 28, 2010 (suppl; abstr e15129)
Kelly Z, Moller-Levet Carla, McGrath S, Butler-Manuel S, Madhuri Thumuluru, Kierzek Andrzej, Pandha Hardev, Morgan Richard, Michael Agnieszka (2016)The prognostic significance of specific HOX gene expression patterns in ovarian cancer, In: International Journal of Cancer139(7)pp. 1608-1617 Wiley
Karapanagiotou E, Pandha HS, Hall G, Chester J, Melcher A, Coffey M, de Bono J, Gore ME, Nutting CM, Harrington KJ (2009)Phase I/II trial of oncolytic reovirus (Reolysin) in combination with carboplatin/paclitaxel in patients (pts) with advanced solid cancers, In: JOURNAL OF CLINICAL ONCOLOGY27(15)
Killick E, Morgan R, Launchbury F, Annels NE, Bancroft E, Page E, Castro E, Kote-Jarai Z, Eeles RA, Pandha HS (2012)Detecting prostate cancer in BRCA1 and BRCA2 mutation carriers: A role for EN2?, In: JOURNAL OF CLINICAL ONCOLOGY30(15)
Michael A, Zylstra J, Pandha H (2011)The sun study-a biobank of sequential blood samples from patients with prostate cancer, In: BRITISH JOURNAL OF SURGERY98pp. 50-50
Binda E, Perez SM, Pandha H, Eberl M, Hayday A (2010)Monitoring the immunological effects of bisphosphonates in different treatment scenarios, In: IMMUNOLOGY131pp. 117-117
Hu JC, Coffin RS, Graham NJ, Groves N, Guest PJ, Harrington KJ, James ND, Love CA, McNeish I, Medley LC, Michael A, Nutting CM, Pandha HS, Shorrock CA, Simpson J, Steiner J, Steven NM, Wright D, Coombes RC (2006)A phase I study of OncoVEXGM-CSF, a second-generation oncolytic herpes simplex virus expressing granulocyte macrophage colony-stimulating factor, In: Clin Cancer Res12(22)pp. 6737-6747
Prestwich RJ, Errington F, Ilett EJ, Morgan RSM, Scott KJ, Kottke T, Thompson J, Morrison EE, Harrington KJ, Pandha HS, Selby PJ, Vile RG, Melcher AA (2008)Tumor Infection by Oncolytic Reovirus Primes Adaptive Antitumor Immunity, In: CLINICAL CANCER RESEARCH14(22)pp. 7358-7366 AMER ASSOC CANCER RESEARCH
McGrath S, Annels NE, Madhuri TK, Haagsma B, Larbi ED, Pandha HS, Michael A (2012)Engrailed protein: A cancer-specific marker in epithelial ovarian cancer, In: JOURNAL OF CLINICAL ONCOLOGY30(15)
Ismail M, Morgan R, Davies J, Pandha H (2009)INHIBITION OF THE AQUAPORIN WATER CHANNELS INCREASES THE SENSITIVITY OF PROSTATE CANCER CELLS TO FREEZING INJURY., In: JOURNAL OF UROLOGY181(4)pp. 185-185
Weinstein S, Nemesure B, Carpten J, Leske C, Wu S-Y, Hennis A, Kibel AS, Rybicki BA, Neslund-Dudas C, Hsing AW, Al Olama AA, Kote-Jarai Z, Berndt SI, Conti DV, Schumacher F, Han Y, Saunders E, Benlloch S, Hazelett DJ, Wang Z, Leongamornlert D, Lindstrom S, Jugurnauth-Little S, Dadaev T, Tymrakiewicz M, Stram DO, Sheng X, Rand K, Wan P, Stram A, Pooler LC, Park K, Xia L, Tyrer J, Kolonel LN, Yeager M, Le Marchand L, Hoover RN, Machiela MJ, Burdette L, Chung CC, Hutchinson A, Yu K, Goh C, Ahmed M, Auvinen A, Govindasami K, Guy M, Tammela TLJ, Wahlfors T, Schleutker J, Visakorpi T, Leinonen KA, Xu J, Aly M, Key TJ, Chu L, Goodman PJ, Klein EA, Donovan J, Travis RC, Siddiq A, Spurdle A, Zheng SL, Batra J, Clements J, Teixeira MR, Paulo P, Maia S, Slavov C, Kaneva R, Mitev V, Kubo M, Canzian F, Khaw K-T, Takahashi A, Pharoah P, Pashayan N, Weischer M, Nordestgaard BG, Nielsen SF, Klarskov P, Seminara D, Witte JS, Casey G, Gillanders EM, Riboli E, Hamdy FC, Coetzee GA, Li Q, Freedman ML, Hunter DJ, McDonnell SK, Roder MA, Iversen P, Thibodeau SN, Schaid DJ, Stanford JL, Kolb S, Holt S, Southey M, Muir K, Gronberg H, Nea DE, Giles GG, Severi G, Cook MB, Nakagawa H, Wiklund F, Kraft P, Diver WR, Knudsen B, Coll AH, Gapstur SM, Stevens VL, Maier C, Luedeke M, Herkommer K, Rinckleb AE, Strom SS, Eeles RA, Chanock SJ, Henderson BE, Easton DF, Haiman CA, Tay E, Pettaway C, Yeboah ED, Tettey Y, Biritwum RB, Adjei AA, Truelove A, Niwa S, Choklcalingam AP, Cannon-Albright L, Cybulski C, Wokolorczyk D, Kluzniak W, Isaacs WB, Park J, Sellers T, Lin H-Y, Partin AW, Brenner H, Dieffenbach AK, Stegmaier C, Chen C, Penney KL, Giovannucci EL, Ma J, Stampfer M, Mucci L, John EM, Ingles SA, Kittles RA, Murphy AB, Blot W, Pandha H, Michael A, Kierzek AM, Signorello LB, Zheng W, Albanes D, Virtamo J (2014)A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer, In: NATURE GENETICS46(10)pp. 1103-1109 NATURE PUBLISHING GROUP
Morgan Richard, Plowright L, Harrington KJ, Michael Agnieszka, Pandha Hardev (2010)Targeting HOX and PBX transcription factors in ovarian cancer, In: BMC CANCER10ARTN 8pp. ?-? BIOMED CENTRAL LTD
Pandha Hardev, Simpson Guy, Melcher A, Prestwich R, Errington F, Coffey M, Harrington KJ, Morgan Richard, Heinemann Lucy (2009)Synergistic Effects of Oncolytic Reovirus and Cisplatin Chemotherapy in Murine Malignant Melanoma, In: Clinical Cancer Research15(19)pp. 6158-6166 American Association for Cancer Research
Ismail M, Bokaee S, Davies J, Harrington KJ, Pandha H (2009)Inhibition of the aquaporin 3 water channel increases the sensitivity of prostate cancer cells to cryotherapy, In: BRITISH JOURNAL OF CANCER100(12)pp. 1889-1895 NATURE PUBLISHING GROUP
Comins C, Spicer J, Protheroe A, Mukherji D, Coffey M, Thompson B, Harrington K, Pandha H (2008)A Phase I Study to Evaluate Systemic Wild-type Reovirus (REOLYSIN)(R) in Combination With Docetaxel in Patients With Advanced Malignancies, In: JOURNAL OF IMMUNOTHERAPY31(9)pp. 951-951
Karapanagiotou EM, Chester JD, Pandha HS, Gill GM, Coffey MC, Mettinger K, Harrington KJ (2010)A phase I/II study of oncolytic reovirus plus carboplatin/paclitaxel in patients with advanced solid cancers with emphasis on squamous cell carcinoma of the head and neck(SCCHN), In: JOURNAL OF CLINICAL ONCOLOGY28(15) AMER SOC CLINICAL ONCOLOGY
Roberts A, Serrano M, Vantourout P, Dieli F, Pandha H, Hayday AC (2010)Expansion of autologous human V gamma 9V delta 2 T cells ex vivo: potential for adoptive T cell therapy of prostate cancer, In: IMMUNOLOGY131pp. 119-119
Pandha S, Simpson GR, Horvath A, Coffin RS, Pencavel T, Harrington K (2011)Combination of a fusogenic glycoprotein, pro-drug activation and oncolytic HSV as an intravesical therapy for superficial bladder cancer (visualised by micro CT), In: BRITISH JOURNAL OF SURGERY98pp. 52-53
Gabitass RF, Annels NE, Pandha HS, Middleton AW (2010)Prevalence and prognostic significance of myeloid-derived suppressor cells and regulatory T cells in pancreatic and esophagogastric cancer, In: JOURNAL OF CLINICAL ONCOLOGY28(15) AMER SOC CLINICAL ONCOLOGY
Kyula JN, Khan AA, Mansfield D, Karapanagiotou EM, Mclaughlin M, Roulstone V, Zaidi S, Pencavel T, Touchefeu Y, Seth R, Chen NG, Yu YA, Zhang Q, Ajaz M, Melcher AA, Vile RG, Pandha HS, Szalay AA, Harrington KJ (2014)Synergistic cytotoxicity of radiation and oncolytic Lister strain vaccinia in V600D/EBRAF mutant melanoma depends on JNK and TNF-α signaling, In: Oncogene33(13)pp. 1700-1712
Kittles RA, Strom SS, Rybicki BA, Nemesure B, Isaacs WB, Zheng W, Pettaway CA, Yeboah ED, Tettey Y, Biritwum RB, Wallinder H, Signorello LB, Blot WJ, Tillmans L, Riska S, Wang L, Rinckleb A, Lubiski J, Stegmaier C, Pow-Sang J, Niwa S, Adjei AA, Tay E, Truelove A, Chokkalingam AP, John EM, Murphy AB, Signorello LB, Carpten J, Leske MC, Haley J, Park H, Radlein S, Rincon M, Zachariah B, Kachakova D, Popov E, Mitkova A, Vlahova A, Dikov T, Hsing AW, Wu S-Y, Hennis AJM, Neslund-Dudas C, Chu L, Goodman PJ, Klein EA, Witte JS, Casey G, Malone G, Christova S, Heathcote P, Wood G, Saunders K, Eckert A, Yeadon T, Kerr K, Blot WJ, Kaggwa S, Cook MB, Stram DO, Eeles RA, Easton D, Kote-Jarai Z, Al Olama AA, Benlloch S, Muir K, Kedda M-A, Collins A, Turner M, Srinivasan S, Gronberg H, Giles GG, Southey MC, Fitzgerald LM, Wiklund F, Aly M, Henderson BE, Schleutker J, Wahlfors T, Tammela TLJ, Henrique R, Alexander K, Omara T, Wu H, Pinto P, Santos J, Neal DE, Nordestgaard BG, Key TJ, Travis RC, Donovan JL, Hamdy FC, Pharoah P, Pashayan N, Khaw K-T, Thibodeau SN, Barros-Silva J, Stanford JL, McDonnell SK, Schaid DJ, Maier C, Vogel W, Luedeke M, Herkommer K, Kibel AS, Cybulski C, Teerlink C, Wokolorczyk D, Kluzniak W, Cannon-Albright L, Brenner H, Dieffenbach AK, Arndt V, Park JY, Sellers TA, Lin H-Y, Batra J, Slavov C, Kaneva R, Mitev V, Spurdle A, Clements JA, Teixeira MR, Pandha HS, Michael A, Conti DV, Paulo P, Maia S, Kierzek A, Albanes D, Berg C, Berndt SI, Campa D, Crawford ED, Diver WR, Hoover R, Gapstur SM, Gaziano JM, Giovannucci E, Hunter DJ, Johansson M, Kraft P, Le Marchand L, Lindstrom S, Navarro C, Stevens VL, Overvad K, Riboli E, Siddiq A, Trichopoulos D, Vineis P, Yeager M, Trynka G, Raychaudhuri S, Schumacher FR, Pasaniuc B, Price AL, Freedman ML, Haiman CA, Cook M, Guy M, Govindasami K, Leongamornlert D, Sawyer EJ, Dadaev T, Wilkinson R, Saunders EJ, Tymrakiewicz M, Morgan A, Fischer C, Hazel S, Hopper JL, Livni N, Lophatananon A, Pedersen J, Adolfson J, Stattin P, Johansson J-E, Cavalli-Bjoerkman C, Karlsson A, Broms M, Pomerantz M, Gusev A, Shi H, Kichaev G, Li F, Long HW, Ingles SA, Murtola T, Auvinen A, Kujala P, Maeaettaenen L, Taari K, Weischer M, Nielsen SF, Klarskov P, Roder A, Iversen P (2016)Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation, In: Nature Communications7
Ismail M, Kevin H, Morgan R, Davies J, Pandha H (2009)ENHANCING PROSTATE CANCER CRYOTHERAPY USING TUMOUR NECROSIS FACTOR RELATED APOPTOSIS-INDUCING LIGAND (TRAIL) SENSITISATION IN A NOVEL IN VITRO MODEL, In: JOURNAL OF UROLOGY181(4)pp. 189-190
Brend T, Kelly Z, Ajaz M, Morgan R, Pandha H, Short SC (2014)THERAPEUTIC POTENTIAL OF TARGETING HOX PROTEIN FUNCTION IN GLIOBLASTOMA, In: NEURO-ONCOLOGY16
Annels Nicola E, Mansfield David, Arif Mehreen, Ballesteros-Merino Carmen, Simpson Guy R, Denyer Mick, Sandhu Sarbjinder S, Melcher Alan, Harrington Kevin J, Davies BronwYn, Au Gough, Grose Mark, Bagwan Izhar N, Fox Bernard A., Vile Richard G, Mostafid Hugh, Shafren Darren, Pandha Hardev Viral targeting of non-muscle invasive bladder cancer and priming of anti-tumour immunity following intravesical Coxsackievirus A21, In: Clinical Cancer Research American Association for Cancer Research
Eisenberger MA, Hardy-Bessard A-C, Mourey L, Mainwaring PN, Ford D, Shapiro JD, Carles J, Ng S, Gil T, Alekseev B, Ivanov S, Facchini T, Legouffe E, Apolikhin O, Zhang W, Pandha HS, Beeker A, Karyakin O, Chadjaa M, De Bono JS (2012)Comparison of two doses of cabazitaxel plus prednisone in patients (pts) with metastatic castration-resistant prostate cancer (mCRPC) previously treated with a docetaxel (D)-containing regimen, In: JOURNAL OF CLINICAL ONCOLOGY30(15)
Rajani K, Parrish C, Kottke T, Thompson J, Zaidi S, Ilett L, Shim KG, Diaz R-M, Pandha H, Harrington K, Coffey M, Melcher A, Vile R (2016)Combination Therapy With Reovirus and Anti-PD-1 Blockade Controls Tumor Growth Through Innate and Adaptive Immune Responses, In: MOLECULAR THERAPY24(1)pp. 166-174 NATURE PUBLISHING GROUP
McGrath SE, Michael A, Morgan R, Pandha H (2015)EN2 in Prostate Cancer., In: Adv Clin Chem71pp. 47-76
Steele L, Errington F, Prestwich R, Ilett E, Harrington K, Pandha H, Coffey M, Selby P, Vile R, Melcher A (2011)Pro-inflammatory cytokine/chemokine production by reovirus treated melanoma cells is PKR/NF-kappa B mediated and supports innate and adaptive anti-tumour immune priming, In: MOLECULAR CANCER10ARTN 20 BIOMED CENTRAL LTD
Roulstone V, Pedersen M, Kyula J, Mansfield D, Khan AA, McEntee G, Wilkinson M, Karapanagiotou E, Coffey M, Marais R, Jebar A, Pandha H, Errington-Mais F, Melcher A, Vile R, McLaughlin M, Harrington KJ (2015)BRAF- and MEK-Targeted Small Molecule Inhibitors Exert Enhanced Antimelanoma Effects in Combination With Oncolytic Reovirus Through ER Stress, In: MOLECULAR THERAPY23(5)pp. 931-942 NATURE PUBLISHING GROUP
Alonso-Camino V, Rajani K, Kottke T, Rommelfanger-Konkol D, Zaidi S, Thompson J, Pulido J, Ilett E, Donnelly O, Selby P, Pandha H, Melcher A, Harrington K, Diaz RM, Vile R (2014)The Profile of Tumor Antigens Which Can be Targeted by Immunotherapy Depends Upon the Tumor's Anatomical Site, In: MOLECULAR THERAPY22(11)pp. 1936-1948 NATURE PUBLISHING GROUP
Rajani K, Shim K, Parrish C, Ilett L, Kottke T, Pulido J, Thompson J, Pandha H, Harrington K, Melcher A, Errington F, Diaz R, Coffey M, Zaidi S, Vile R (2015)Combination Therapy of Reovirus and PD-1 Blockade Effectively Establishes Tumor Control Via Innate and Adaptive Immune Responses, In: MOLECULAR THERAPY23pp. S30-S30
Michael A, Riley, C, Bokaee S, Denyer M, Pandha H, Annels N (2011)EN2: A candidate antigen for the development of targeted therapies in ovarian cancer., In: JCO(J Clin)
Gabitass RF, Annels NE, Stocken DD, Pandha HA, Middleton GW (2011)Elevated myeloid-derived suppressor cells in pancreatic, esophageal and gastric cancer are an independent prognostic factor and are associated with significant elevation of the Th2 cytokine interleukin-13., In: Cancer Immunol Immunother
Samson A, Scott K, Taggart D, West E, Wilson E, Nuovo G, Thomson S, Corns R, Mathew R, Fuller M, Kottke T, Thompson J, Ilett E, Cockle J, van Hille P, Appleton E, Sivakumar G, Polson E, Turnbull S, Migneco G, Rose A, Coffey M, Beirne D, Collinson F, Ralph C, Quezada S, Anthoney D, Twelves C, Furness A, Wurdak H, Errington-Mais F, Pandha Hardev, Harrington K, Selby P, Vile R, Melcher A, Griffin S, Stead L, Short S (2018)Intravenous Delivery of Oncolytic Reovirus to Brain Tumor Patients Immunologically Primes for Subsequent Checkpoint Blockade, In: Science Translational Medicine10(422)eaam7577 American Association for the Advancement of Science
Vile Richard G., Melcher Alan A., Errington-Mais Fiona, Jennings Victoria A., Scott Gina B., Rose Ailsa M.S., Reilly Katrina, Scott Karen J., Migneco Gemma, Keller Brian, Donnelly Oliver, Peach Howard, Dewar Donald, Harrington Kevin J., Pandha Hardev, Samson Adel Potentiating Oncolytic Virus-Induced Immune-Mediated Tumor Cell Killing Using Histone Deacetylase Inhibition, In: Molecular Therapy Elsevier
Pashayan N, Khaw K-T, Stanford JL, Thibodeau SN, McDonnell SK, Schaid DJ, Maier C, Vogel W, Luedeke M, Herkommer K, Kibel AS, Cybulski C, Brenner H, Lubinski J, Kluzniak W, Cannon-Albright L, Herrmann V, Holleczek B, Park JY, Sellers TA, Lim H-Y, Slavov C, Aly M, Szulkin R, Karlsson R, Whitington T, Gronberg H, Eeles RA, Easton DF, Teixeira MR, Kaneva RP, Mitev VI, Spurdle A, Paulo P, Maia S, Pandha H, Michael A, Kierzek A, Batra J, Muir K, Kote-Jarai Z, Al Olama AA, Benlloch S, Giles GG, Southey MC, FitzGerald LM, Henderson BE, Schumacher FR, Haiman CA, Berndt SI, Clements JA, Albanes D, Andriole GL, Chanock S, Gapstur SM, Giovannucci EL, Hunter DJ, Kraft P, Le Marchand L, Key TJ, Sipeky C, Tammela TLJ, Nordestgaard BG, Travis RC, Neal DE, Donovan JL, Hamdy FC, Pharoah PDP, Stampfer MJ, Ma J, Mondul AM, Penney KL, Stevens VL, Weinstein SJ, Trichopoulou A, Bueno-de-Mesquita BH, Tjonneland A, Cox DG, Wiklund F, Maehle L, Schleutker J, Lindstroem S (2015)Genome-Wide Association Study of Prostate Cancer-Specific Survival, In: CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION24(11)pp. 1796-1800 AMER ASSOC CANCER RESEARCH
Ismail MI, Bokaee S, Annels N, Davies J, Pandha H (2011)Predominance of CD8 T cell infiltration coincides with reciprocal reduction in regulatory T cells following prostate cryotherapy, In: BRITISH JOURNAL OF SURGERY98pp. 48-48
Larkin SET, Johnston HE, Jackson TR, Jamieson DG, Roumeliotis TI, Mockridge CI, Manousopoulou A, Papachristou EK, Brown MD, Clarke NW, Pandha HS, Townsend PA, Aukim-Hastie CL, Cragg MS, Garbis SD (2016)Detection of candidate biomarkers of prostate cancer progression in serum: a depletion-free 3D LC/MS quantitative proteomics pilot study, In: British Journal of Cancer Springer Nature
Plowright L, Harrington KJ, Pandha HS, Morgan R (2009)HOX transcription factors are potential therapeutic targets in non-small-cell lung cancer (targeting HOX genes in lung cancer), In: BRITISH JOURNAL OF CANCER100(3)pp. 470-475 NATURE PUBLISHING GROUP
Javed S, Pandha H, Morgan R, Bott S, Eden C, Langley S (2013)Urinary Engrailed-2 (EN2) levels and their correlation with tumour volume and pathological tumour stage in men undergoing radical prostatectomy for prostate cancer, In: BJU INTERNATIONAL111pp. 12-12
Donnelly O, Vile R, Pandha H, Harrington K, Melcher A (2012)The hitchhiker's guide to virotherapy., In: Oncotarget3(8)pp. 735-736
Mansfield D, Pencavel T, Kyula JN, Zaidi S, Roulstone V, Thway K, Karapanagiotou L, Khan AA, McLaughlin M, Touchefeu Y, Seth R, Melcher AA, Vile RG, Pandha HS, Harrington KJ (2012)Oncolytic Vaccinia virus and radiotherapy in head and neck cancer., In: Oral Oncol
John J, Ismail M, Riley C, Askham J, Morgan R, Melcher A, Pandha H (2010)Differential effects of Paclitaxel on dendritic cell function, In: BMC IMMUNOLOGY11ARTN 14 BIOMED CENTRAL LTD
Twigger K, Vidal L, White CL, De Bono JS, Bhide S, Coffey M, Thompson B, Vile RG, Heinemann L, Pandha HS, Errington F, Melcher AA, Harrington KJ (2008)Enhanced in vitro and in vivo cytotoxicity of combined reovirus and radiotherapy, In: CLINICAL CANCER RESEARCH14(3)pp. 912-923 AMER ASSOC CANCER RESEARCH
Plowright L, Shears L, Pandha H, Morgan R (2007)Disrupting the interaction between Hox and PBX causes apoptotic cell death and reduces in vivo proliferation of a non-small cell lung cancer model, In: MOLECULAR CANCER THERAPEUTICS6(12)pp. 3504S-3504S AMER ASSOC CANCER RESEARCH
Kelly ZL, Michael Agnieszka, Butler-Manuel S, Pandha Hardev, Morgan Richard (2011)HOX genes in ovarian cancer, In: Journal of Ovarian Research4(1) Springer
Motzer Robert J, Ravaud Alain, Patard Jean-Jacques, Pandha Hardev, George Daniel J, Patel Anup, Chang Yen-Hwa, Escudier Bernard, Donskov Frede, Magheli Ahmed, Breza Jan, Carteni Giacomo, Laguerre Brigitte, Tomczak Piotr, Gerletti Paola, Lechuga Mariajose, Lin Xun, Casey Michelle, Serfass Lucile, Pantuck Allan J, Staehler Michael (2017)Adjuvant Sunitinib for High-risk Renal Cell Carcinoma After Nephrectomy: Subgroup Analyses and Updated Overall Survival Results, In: European Urology73(1)pp. 62-68 Elsevier
Morgan R, Pandha HS Antagonism of HOX/PBX dimer formation blocks the in vivo proliferation of melanoma, In: Cancer Research67(12)pp. 5806-5813 American Association for Cancer Research
Vile R, Melcher A, Errington F, Steele L, Prestwich R, Harrington KJ, Pandha HS, Vidal L, de Bono J, Selby P, Coffey M (2008)Reovirus activates human dendritic cells to promote innate antitumor immunity, In: JOURNAL OF IMMUNOLOGY180(9)pp. 6018-6026 AMER ASSOC IMMUNOLOGISTS
Errington F, White CL, Twigger KR, Rose A, Scott K, Steele L, Ilett LJ, Prestwich R, Pandha HS, Coffey M, Selby P, Vile R, Harrington KJ, Melcher AA (2008)Inflammatory tumour cell killing by oncolytic reovirus for the treatment of melanoma, In: GENE THERAPY15(18)pp. 1257-1270 NATURE PUBLISHING GROUP
Horvath A, Simpson GR, Coffin RS, Mostafid H, Pandha H (2009)NOVEL INTRAVESICAL THERAPY FOR NON MUSCLE INVASIVE BLADDER CANCER: COMBINATION OF A FUSOGENIC GLYCOPROTEIN, PRO-DRUG ACTIVATION AND ONCOLYTIC HERPES SIMPLEX VIRUS, In: EUR UROL SUPPL8(4)pp. 196-196 ELSEVIER SCIENCE BV
Comins C, Simpson GR, Relph K, Harrington KJ, Melcher A, Pandha H (2013)Reoviral Therapy for Cancer: Strategies for Improving Antitumor Efficacy Using Radio- and Chemotherapypp. 185-198
Pandha H, Pawelec G (2015)Immune checkpoint targeting as anti-cancer immunotherapy: promises, questions, challenges and the need for predictive biomarkers at ASCO 2015, In: CANCER IMMUNOLOGY IMMUNOTHERAPY64(9)pp. 1071-1074 SPRINGER
Zaidi S, Blanchard M, Shim K, Ilett E, Rajani K, Parrish C, Boisgerault N, Kottke T, Thompson J, Celis E, Pulido J, Selby P, Vile R, Pandha H, Melcher A, Harrington K (2015)Mutated BRAF Emerges as a Major Effector of Recurrence in a Murine melanoma Model After Treatment With Immunomodulatory Agents, In: MOLECULAR THERAPY23(5)pp. 845-856 NATURE PUBLISHING GROUP
De Paoli M, Gogalic S, Sauer U, Preininger C, Pandha HS, Simpson G, Horvath A, Marquette C (2016)Multi-platform biomarker discovery for bladder cancer recurrence diagnosis, In: Disease Markers4591910 Hindawi Publishing Corporation
Whitaker Hayley, Connell Shea P., Yazbek-Hanna Marcelino, McCarthy Frank, Hurst Rachel, Webb Martyn, Curley Helen, Walker Helen, Mills Rob, Patil Dattatraya, Ball Richard Y., Sanda Martin G., Pellegrini Kathryn L., Perry Antoinette S., Schalken Jack, Pandha Hardev, Whitaker Hayley, Dennis Nening, Stuttle Christine, Brewer Daniel S., Mills Ian G., Guldvik Ingrid, Parker Chris, Cooper Colin S., Clark Jeremy, Bapat Bharati, Bristow Rob, Doll Andreas, Clark Jeremy, Neal David, Cooper Colin, Leung Hing, Mills Ian, Olivan Mireia, Pandha Hardev, Perry Antoinette, Parker Chris, Sanda Martin, Schalken Jack (2019)A four-group urine risk classifier for predicting outcomes in patients with prostate cancer, In: BJU International Wiley
Adair RA, Roulstone V, Scott KJ, Morgan R, Nuovo GJ, Fuller M, Beirne D, West EJ, Jennings VA, Rose A, Kyula J, Fraser S, Dave R, Pandha H, Anthoney DA, Merrick A, Prestwich R, Aldouri A, Donnelly O, Coffey M, Selby P, Vile R, Toogood G, Harrington K, Melcher AA (2012)Cell carriage, delivery, and selective replication of an oncolytic virus in tumor in patients., In: Sci Transl Med4(138)pp. 138ra77-?
Seibert Tyler M, Fan Chun Chieh, Wang Yunpeng, Zuber Verena, Karunamuni Roshan, Parsons J Kellogg, Eeles Rosalind A, Easton Douglas F, Kote-Jarai ZSofia, Al Olama Ali Amin, Garcia Sara Benlloch, Muir Kenneth, Schleutker Johanna, Grönberg Henrik, Wiklund Fredrik, Aly Markus, Sipeky Csilla, Tammela Teuvo LJ, Nordestgaard Børge G, Nielsen Sune F, Weischer Maren, Key Tim J, Bisbjerg Rasmus, Røder M Andreas, Iversen Peter, Travis Ruth C, Neal David E, Donovan Jenny L, Hamdy Freddie C, Pharoah Paul, Pashayan Nora, Luedeke Manuel, Khaw Kay-Tee, Maier Christiane, Vogel Walther, Herkommer Kathleen, Kibel Adam S, Cybulski Cezary, Wokolorczyk Dominika, Kluzniak Wojciech, Saum Kai-Uwe, Cannon-Albright Lisa, Brenner Hermann, Cuk Katarina, Park Jong Y, Sellers Thomas A, Slavov Chavdar, Kaneva Radka, Mitev Vanio, Batra Jyotsna, Paulo Paula, Clements Judith A, Spurdle Amanda, Teixeira Manuel R, Maia Sofia, Pandha Hardev, Michael Agnieszka, Kierzek Andrzej, Karow David S, Mills Ian G, Andreassen Ole A, Dale Anders M (2018)Polygenic hazard score to guide screening for aggressive prostate cancer: development and validation in large scale cohorts, In: BMJ360j5757pp. 1-7 BMJ Publishing Group
Pharoah P, Pashayan N, Khaw K-T, Stanford JL, Thibodeau SN, McDonnell SK, Schaid DJ, Maier C, Vogel W, Luedeke M, Herkommer K, Kibel AS, Cybulski C, Lubinski J, Kluzniak W, Cannon-Albright L, Brenner H, Butterbach K, Stegmaier C, Park JY, Kaneva R, Sellers T, Lim H-Y, Slavov C, Mitev V, Batra J, Clements JA, Spurdle A, Teixeira MR, Paulo P, Kierzek A, Maia S, Pandha H, Michael A, Gronberg H, Wiklund F, Aly M, Szulkin R, Whitington T, Eklund M, Eeles RA, Benlloch S, Easton D, Kote-Jarai Z, Al Olama AA, Muir K, Giles GG, Southey MC, Fitzgerald LM, Henderson BE, Schumacher F, Tammela TLJ, Haiman CA, Schleutker J, Wahlfors T, Nordestgaard BG, Key TJ, Travis RC, Neal DE, Donovan JL, Hamdy FC (2015)Prediction of Individual Genetic Risk to Prostate Cancer Using a Polygenic Score, In: PROSTATE75(13)pp. 1467-1474 WILEY-BLACKWELL
Jebar A, West E, Scott K, Thomson S, Corns R, Coffey MC, Rose A, Nuovo G, Ryan M, Errington-Mais F, Ralph C, Twelves C, Griffin S, Harrington KJ, Pandha HS, Donnely O, Selby PJ, Vile R, Short S, Melcher A (2014)Oncolytic wild-type reovirus infection in brain tumors following intravenous administration in patients., In: JOURNAL OF CLINICAL ONCOLOGY32(15)
Melcher AA, Pandha HS, Harrington KJ, White CL, Menghistu T, Twigger KR, Searle PF, Bhide SA, Vile RG (2008)Escherichia coli nitroreductase plus CB1954 enhances the effect of radiotherapy in vitro and in vivo, In: GENE THERAPY15(6)pp. 424-433 NATURE PUBLISHING GROUP
Vogelzang NJ, Beer TM, Bartunkova J, Kuklk R, Miller K, Oh WK, Oudard S, Pandha HS, Sartor AO, Spisek R, Borgstein NG, Gerritsen WR (2015)Autologous dendritic cell vaccination (DCVAC/PCa) added to docetaxel chemotherapy in a double-blind, randomized phase III trial (VIABLE) in men with advanced (mCRPC) prostate cancer., In: JOURNAL OF CLINICAL ONCOLOGY33(15)
Ravaud A, Motzer RJ, Pandha Hardev S., George DJ, Pantuck AJ, Patel A, Chang YH, Escudier B, Donskov F, Magheli A, Carteni G, Laguerre B, Tomczak P, Breza J, Gerletti P, Lechuga M, Lin X, Martini JF, Patard JJ, Ramaswamy K, Casey M, Staehler M (2016)Adjuvant Sunitinib in High-Risk Renal-Cell Carcinoma after Nephrectomy, In: New England Journal of Medicine375pp. 2246-2254 Massachusetts Medical Society
Errington F, Harrington KJ, Pandha HS, Selby P, Melcher A, Prestwich RJ (2008)Oncolytic viruses: do they have a role in anti-cancer therapy?, In: Clin Med Oncol2pp. 83-96
Jebar A, Bentham M, Errington-Mais F, Scott K, Peckham-Cooper A, Dave R, Toogood G, Swinson D, Ralph C, Anthoney A, Coffey M, Harrington K, Pandha H, Vile R, Selby P, Melcher A, Griffin S (2014)Combined anti-viral and anti-tumour therapy for virus-associated liver cancer, In: HUMAN GENE THERAPY25(12)pp. A27-A27
Ilett EJ, Barcena M, Errington-Mais F, Griffin S, Harrington KJ, Pandha HS, Coffey M, Selby PJ, Limpens RWAL, Mommaas M, Hoeben RC, Vile RG, Melcher AA (2011)Internalization of Oncolytic Reovirus by Human Dendritic Cell Carriers Protects the Virus from Neutralization, In: CLINICAL CANCER RESEARCH17(9)pp. 2767-2776 AMER ASSOC CANCER RESEARCH
Bonilla C, Lewis SJ, Rowlands M, Gaunt TR, Davey Smith G, Gunnell D, Palmer T, Donovan JL, Hamdy FC, Neal DE, Eeles R, Easton D, Kote-Jarai Z, Giles GG, Al Olama AA, Benlloch S, Muir K, Wiklund F, Gronberg H, Haiman CA, Schleutker J, Nordestgaard BG, Travis RC, Blot WJ, Pashayan N, Khaw K, Stanford JL, Thibodeau S, Maier C, Kibel AS, Cybulski C, Cannon-Albright L, Brenner H, Teixeira MR, Park J, Kaneva R, Batra J, Pandha HS, PRACTICAL consortium M, Lathrop RM, Martin JMP, Holly (2016)Assessing the role of insulin-like growth factors and binding proteins in prostate cancer using Mendelian randomization: genetic variants as instruments for circulating levels, In: International Journal of Cancer139(7)pp. 1520-1533
de Bono JS, Piulats JM, Pandha HS, Petrylak DP, Saad F, Aparicio LMA, Sandhu SK, Fong P, Gillessen S, Hudes GR, Wang T, Scranton J, Pollak MN (2014)Phase II Randomized Study of Figitumumab plus Docetaxel and Docetaxel Alone with Crossover for Metastatic Castration-Resistant Prostate Cancer, In: CLINICAL CANCER RESEARCH20(7)pp. 1925-1934 AMER ASSOC CANCER RESEARCH
Zhao Fang, Olkhov-Mitsel Ekaterina, Kamdar Shivani, Jeyapala Renu, Garcia Julia, Hurst Rachel, Hanna Marcelino Yazbek, Mills Robert, Tuzova Alexandra V., O’Reilly Eve, Kelly Sarah, Cooper Colin, Brewer Daniel, Bapat Bharati, Perry Antoinette S., Clark Jeremy, Fleshner Neil, Parker Chris, Cooper Colin, Bapat Bharati, Bristow Rob, Mills Ian, Pandha Hardev, Whitaker Hayley, Perry Antoinette, Neal David, Olivan Mireia, Leung Hing, Sanda Martin, Schalken Jack (2018)A urine-based DNA methylation assay, ProCUrE, to identify clinically significant prostate cancer, In: Clinical Epigenetics10147pp. 1-12
Pchejetski D, Cutress R, Murray N, Michael A, Annels NE, Falgari G, Simpson GR, Denyer M, McGrath SE, Killick E, Eeles R, Stebbing J, Pandha H (2014)Spontaneous antibodies against Engrailed-2 (EN2) protein in patients with prostate cancer, In: CLINICAL AND EXPERIMENTAL IMMUNOLOGY177(2)pp. 428-438 WILEY-BLACKWELL
Bensen Jeanette T, Kogevinas Manolis, Penney Kathryn L, Park Jong Y, Stanford Janet L, Cybulski Cezary, Nordestgaard Børge G, Brenner Hermann, Maier Christiane, Kim Jeri, Teixeira Manuel R, Neuhausen Susan L, De Ruyck Kim, Razack Azad, Newcomb Lisa F, Lessel Davor, Kaneva Radka, Usmani Nawaid, Roobol Monique J, Claessens Frank, Townsend Paul A, Dominguez Manuela G, Menegaux Florence, Khaw Kay-Tee, Cannon-Albright Lisa A, Pandha Hardev, Thibodeau Stephen N, Easton Douglas F, Schaid Daniel J, Wiklund Fredrik, Chanock Stephen J, Eeles Rosalind A, Kote-Jarai Zsofia, Conti David V, Haiman Christopher A, Dadaev Tokhir, Matejcic Marco, Saunders Edward J, Al Olama Ali Amin, Brook Mark N, Wang Kan, Sheng Xin, Schumacher Fredrick R, Ingles Sue A, Govindasami Koveela, Benlloch Sara, Berndt Sonja I, Albanes Demetrius, Gapstur Susan M, Koutros Stella, Muir Kenneth, Stevens Victoria L, Tangen Catherine M, Batra Jyotsna, Clements Judith, Gronberg Henrik, Pashayan Nora, Mucci Lorelei, Schleutker Johanna, Wolk Alicja, West Catharine, Kraft Peter, Cancel-Tassin Géraldine, Sorensen Karina D, Maehle Lovise, Grindedal Eli M, Strom Sara S, Travis Ruth C, Neal David E, Hamdy Freddie C, Donovan Jenny L, Hamilton Robert J, Rosenstein Barry, Lu Yong-Jie, Giles Graham G, Kibel Adam S, Vega Ana (2018)Germline variation at 8q24 and prostate cancer risk in men of European ancestry, In: Nature Communications94616 Nature Research