Dr Gerardo Aquino

Research Fellow in Mathematical Biology



Dr. Gerardo Aquino is a research associate in the Mathematical Biology group led by Andrea Rocco working on stochastic dynamics in cell differentiation, single receptor and cooperative receptors models of cell sensing, using information theory, bayesian inference and both equilibrium and non-equilibrium statistical mechanics approaches. His main research interests fall within the broad areas of decision making in single cells and modelling complex systems in physics and biology.

Research interests

Research collaborations


  • L. Vibert, G. Aquino, A. Rocco and R. KelshAn ongoing role for Wnt signalling in dierentiating melanocytes in vivo.(accepted forpublication on Pigment Cell & Melanoma Research (2016).)
  • G. Aquino,N. Wingreen, R. G. EndresKnow the single-receptor sensing limit? Think again.Journal of Statistical Physics, Nov. 2015 (available online).
  • G. Aquino*, M. ZapotockyInformation transfer through a signaling module with feedback: a perturbative approachBiosystems, 136, 66-72 (2015)
  • G. Micali, G. Aquino, D. Richards, R. G. EndresAccurate encoding and decoding by single cells: amplitude versus frequency modulationPLoS Comp. Bio. 11(6): e1004222 (2015).
  • G. Aquino, L. Tweedy. D. Heindrich, R.G. EndresMemory improves precision of cell sensing in fluctuating environments Sci. Rep. 4, 588 (2014).
  • M. Bologna, G. Aquino*Weakly driven diffusion in nonergodic regime: an analytical solution.Eur. Phys. J. B 87, 15 (2014).
  • G. Aquino**, S. Pageon, K. Lagrue, K. Kohler, R. G. Endres, D. DavisDynamics of Natural Killer cell receptor by quantitative analysis of photoswitchableprotein. Biophys. J. 105, 1-10 (2013).
  • G. Aquino*, M. Bologna, P. Grigolini, B. J. WestTransmission of information between complex systems: 1/f resonance.Phys. Rev. E 83, 051130 (2011).
  • G. Aquino*, D. Clausnitzer, S. Tollis and R.G. EndresOptimal receptor-cluster size determined by intrinsic and extrinsic noise.Phys. Rev. E 83, 021914 (2011).
  • G. Aquino* and R.G. EndresIncreased accuracy of ligand sensing by receptor diffusion on cell surface.Phys. Rev. E 82, 041902 (2010).
  • G. Aquino* and R. G. EndresIncreased accuracy of ligand sensing by receptor internalizationPhys. Rev. E 81, 021909 (2010).
  • G. Aquino*, M. Bologna, P. Grigolini, B. J. WestBeyond the death of linear response theory:1/f optimal information transport.Phys. Rev. Lett. 105, 040601 (2010).
  • G. Aquino, M. Bologna and H. CalistoAn exact analytical solution for generalized growth models driven by dichotomic noise.Europhys. Lett. 89, 50012 (2010).
  • P. Grigolini, G. Aquino, M. Bologna, M. Lukovic and B. J. WestA theory of 1/f-noise in human cognition.Physica A:Statistical Mechanics and its Applications 388, 4192-4204 (2009).
  • G. Aquino* and F. GiraldiEntanglement entropy and determination of an unknown quantum state.Phys. Rev. A, 78, 062115 (2008).
  • G. Aquino*, A. Allahverdyan, Th. M. NieuwenhuizenMemory eects in the standard model for glasses.Phys. Rev. Lett. 101, 015901, (2008) arXiv:0710.2650
  • G. Aquino*, P. Grigolini, B. J. WestLinear Response and Fluctuation Dissipation Theorem in non-Poissonian Renewal Processes.Europhys. Lett. 80 , 10002 (2007).
  • G. Aquino*, L. Leuzzi, Th. M. NieuwenhuizenKovacs effect in a fragile glass model. Phys. Rev. B 73, 094205 (2006).
  • G. Aquino*, L. Palatella, P. GrigoliniAbsorption and Emission in the non-Poissonian case: The theoretical challenge posed by renewal aging.Braz. J. of Phys. 2b, p. 418-424 (2005)
  • P. Allegrini, G. Aquino*, P. Grigolini, L. Palatella, A. Rosa, B. J. West:Correlation functions and Generalized Master Equation of arbitrary age.Phys. Rev. E 71, 066109 (2005).
  • G. Aquino*, L. Palatella , P. Grigolini:Absorption and emission in the non-Poissonian case.Phys. Rev. Lett. 93, 050601 (2004).
  • G. Aquino*, M. Bologna, P. Grigolini, B. J. West:Aging and rejuvination with fractional derivatives. Phys. Rev. E 70, 036105 (2004).
  • P. Allegrini, G. Aquino*, P. Grigolini, L. Palatella, A. Rosa:Generalized master equation via aging continuous-time random walks.Phys. Rev. E 68, 056123 (2003)
  • G. Aquino*, N.Scafetta, P.Grigolini:Sporadic randomness, Maxwell's demon and the Poincare' recurrence times.Chaos, Solitons and Fractals 12, 2023 (2001).Proceedings
  • G. Aquino and B. MehmaniSimultaneous measurement of non-commuting observables., Proceedings of the workshopBeyond the Quantum" T. M. Nieuwenhuizen, V. Spicka eds., World Scienti c,Singapore, 2007, pp. 115-124.
  • G. Aquino*, L. Leuzzi, Th. M. NieuwenhuizenKovacs eect in solvable model glasses.Luxembourg 14-25 Sep 2005, J. Phys.: Conf. Ser. 40, 50-58 (2006).P. Allegrini, G. Aquino, M. Bologna et al.Decoherence, wave function collapses, non-ordinary statistical mechanics and the sec-ond principle. AIP Conf. Proceedings 643 pp. 72-76. November 20, 2002.