My general research interests are focused on applying molecular biology techniques to investigate Mycobacterium tuberculosis pathogenesis. Specifically, the identification of essential metabolic pathways and a more complete understanding of how mycobacteria detect and respond to their environment may identify novel drug targets to treat tuberculosis, the cause of 1.4 million deaths worldwide in 2012.
More specifically, my research interests are aimed at understanding nitrogen metabolism in M. tuberculosis. Nitrogen is an essential element for bacterial growth yet the nitrogen sources available to M. tuberculosis in vivo and the metabolic pathways used by the pathogen to assimilate nitrogen and survive in the host are unknown. A more comprehensive understanding of these essential processes could help identify novel drug targets to treat tuberculosis.
- Lecturer MSc Medical Microbiology (EuroMasters), University of Surrey
- Final Year Undergraduate Research Project Supervisor, BSc Biomedical Science, University of Surrey
- External Lecturer, MSc Medical Microbiology, London School of Hygiene & Tropical Medicine (LSHTM)
- External Lecturer, BSc Biomedical Science, Royal Veterinary College, London
- Lecturer, BSc Biology & BSc Infection & Immunity, Imperial College London
- Member of the Royal Society of Chemistry
- Member of the Society for General Microbiology
- NEBOSH National General Certificate in Occupational Safety and Health (Level 3)
- Introductory Certificate in Management (Level 3), Chartered Management Institute
- Royal Society of Chemistry Chartered Chemist (CChem)
Most recent publication:
• Williams, KJ; Jenkins, VA; Barton, GR; Bryant WB; Krishnan, N; Robertson BD. (2015). Deciphering the metabolic response of Mycobacterium tuberculosis to nitrogen stress. Mol Micro 97(6):1142-57