Section of Metabolic Medicine, Food & Macronutrients
The Section of Metabolic Medicine, Food and Macronutrients researches the metabolic origins and prevention of disease.
An overall aim of the Section is to increase understanding of the aetiology and metabolic basis of chronic degenerative diseases, such as cardiovascular disease and diabetes, and to produce evidence for the health benefits of therapeutic, diet and lifestyle strategies to reduce disease risk.
Professor Bruce Griffin researches the impact of diet and lifestyle factors on lipid and lipoprotein metabolism in relation to cardiovascular health. His interest is in understanding the mechanisms that underlie the origins and prevention of cardio-metabolic risk, and specifically, the roles of dietary fatty acids, cholesterol, carbohydrates and sugars.
Professor Margot Umpleby has an extensive track record in using stable isotopes for the study of human metabolism. Her research aims to understand the mechanisms that lead to insulin resistance and abnormalities in fatty acid and lipoprotein metabolism in diabetes, obesity, metabolic syndrome and non-alcoholic fatty liver disease.
Dr Denise Robertson has a research interest in the role of diet and lifestyle in the prevention and treatment of chronic diseases, such as type 2 diabetes, with a special interest in the role of dietary fibres and gastrointestinal metabolism.
Dr Barbara Fielding is an expert in lipid metabolism and in using stable isotopes as tracers of metabolism in studies from bench to bedside. These studies further our understanding of the interaction between macronutrients, exercise, therapeutic agents and basic metabolic pathways in health and disease.