Lampros Stergioulas

Professor Lampros Stergioulas


Professor in Business Analytics
+44 (0)1483 686327
02 MS 02
3-4:30pm Tuesday; 3-4:30pm Wednesday

Biography

Biography

Lampros Stergioulas is Professor in Business Analytics at the University of Surrey. He has studied Informatics and Physics in his first degree and received M.Sc. and Ph.D. in Electrical Engineering from the University of Liverpool, UK. He has published over 150 scientific publications and has supervised and examined numerous PhD dissertations in information systems and computer science. He has held many national and EU Grants in information systems, human-centred communications and computing, medical and health informatics, information processing, and intelligent systems. He has been principal investigator in numerous EU projects, including UNIVERSAL (FP5), TIME2LEARN (FP5), PROLEARN (FP6), BASE2 (FP6), HoTEL, OpenScout, iCOPER and ODS, and Coordinator of the e-Start, TEL-Map, DYRECT, and CRe-AM European research projects.

Research interests

Business Analytics, Strategic Planning, Data-driven Management, Digital Entrepreneurship, Information Systems, System Modeling and Simulation

Research collaborations

RESEARCH PROJECTS

https://designscapes.eu/

https://vac4eu.org/

http://www.opendiscoveryspace.eu

http://www.advance-vaccines.eu/

 

Teaching

MSc Business Analytics

My publications

Publications

Naseer A, Stergioulas L (2009) Convergence of grids and web services: Current challenges and future directions, Proceedings of the International Conference on Management of Emergent Digital EcoSystems, MEDES '09 pp. 290-294
Fully-converged Grids and Web Services (WSs) can lead to the development of a new infrastructure that would offer a more powerful set of networking capabilities and features. On one hand, this convergence was favourably looked at, with the expectation of providing better technical solutions to highly complex business problems while, on the other hand, it was seen as an impossible task, bearing considerable risk and presenting many challenges along the way, resulting in a permanent rift between the two paradigms, Grids and WSs. This paper presents an overview of the past and ongoing efforts towards realizing this convergence, its potential benefits and the risks involved and measures to avoid them. Furthermore, we argue that if this convergence is unsuccessful, with future WSs moving away from Grid-oriented principles and implementations, the concept of Grids might fade gradually away, giving way to the competing technologies. The Grid paradigm however offers certain advantages and is in this sense irreplaceable. Faced with the prospects of non-convergence and consequent demise, in order to achieve a viable Grid infrastructure, Grids need to maintain their identity by providing application-oriented, real-world enterprise solutions to business applications. Grid technology would need more and more to be applied in a practical and efficient way to real use cases, to demonstrate its comparative advantage over other competing technologies. In order to fully exploit the potential of WSs, Grid technology needs to come out from its internal tussle of definitions, standards, etc. which has been a major set-back for the future of Grids, not only in the past but also at present, and move forward faster in terms of its implementation in real-world enterprise use cases and applications. Copyright 2009 ACM.
Qazi SA, Stergioulas LK (2006) Higher order nested wigner distributions: Properties and applications, IEEE Transactions on Signal Processing 54 (12) pp. 4662-4674
The concept of Wigner distribution (WD) is extended to higher-order nested Wigner distributions. The nested ambiguity function (NAF) is also derived naturally by employing the known interrelation between the WD and the ambiguity function (AF). These distributions are obtained by nesting a function within itself a number of times. The definitions of these,new multidimensional distributions are given in analogy to the standard first-order 2-D distributions in both temporal/spatial and spectral forms and follow the definitions of quartic distributions presented in [21] and [22]. Some important properties are derived and discussed, including interrelationships between the various representations, marginals, correlations, and uncertainties, as well as their geometrical characteristics. The second-order nested Wigner distribution (NWD) is used to showcase the power of such distributions in potential application areas, such as signal estimation, signal separation, and radar signal analysis. For such signal processing tasks, it is demonstrated that the NWDs can be successful in situations where the standard 2-D distributions have proved to be inadequate. © 2006 IEEE.
Xydopoulos G, Stergioulas LK (2011) Evaluating health information system interventions using analytical and modeling methods, Proceedings of the European, Mediterranean and Middle Eastern Conference on Information Systems - Informing Responsible Management: Sustainability in Emerging Economies, EMCIS 2011 pp. 252-259
In recent years the value of the use of evaluation methods in all aspects of economic sectors, including the field of health care, has been increasingly recognized. The thrust of this paper is to explore the potential use of a) Cost-Benefit Analysis and b) Simulation and Modeling methods in estimating the value of Health Information System (HIS) projects. These methods were chosen for consideration as the most appropriate, primarily because CBA can measure delivered value of HIS interventions by weighting cost and benefits and identifying what is more socially desirable, while Simulation and Modeling tools can be used to estimate the future value of health care changes concerning HIS. The paper discusses these two families of methods, their evaluation potential is analyzed, and arguments for and against the use of each method are presented. Finally, methodological considerations and limitations are discussed and areas for future research are suggested.
Naseer A, Stergioulas LK (2007) Combining web services and grid services: Practical approaches and implications to resource discovery, pp. 298-317
Web technologies have played a significant role in supporting the global sharing of Internet resources and thereby improving communications. On another front, Grids hold the promise to provide global interoperability and interconnectivity at a level considered impossible a few decades ago. In practice, there is not much difference between the existing Grid and Web infrastructures; in fact, a Grid infrastructure could be built by making minor modifications to a Web infrastructure. The implementation of Web-based Grids or a partially-Gridified Web is one of the potential solutions to Grid infrastructure problems. This can be done by sharing Grid services across the Grid infrastructure, effectively using the underlying Web services as vehicles or transporters of these services. The chapter discusses Grid services as another type of Grid resources, examines possible ways to integrate Grid services and Web services, and explores how this will support Grid resource discovery. It is argued that Grids should be developed using the underlying Web infrastructure and Grid services could be integrated with Web services using inheritance techniques to produce Grid-supported Web services. Furthermore, this approach seems to deal effectively with the problems of resource discovery in such partially-Gridified Web environments. An earlier version of this work has been presented in Naseer and Stergioulas (2006a). © 2008, IGI Global.
Mohammad Y, Stergioulas L (2010) Building an information security strategy for EHR: guidelines for assessing the current situation., Conf Proc IEEE Eng Med Biol Soc 2010 pp. 3919-3922
This paper is looking at electronic health record (EHR) systems and their information security strategy. It focuses on the first step of building an information security strategy which is analysing the current situation of an EHR system. This research is based on different research methods applied to different EHR systems. In this paper we define eight elements that can be used as guidelines for how best to assess the current situation of any EHR system.
Kamtsiou V, Naeve A, Stergioulas L, Pappa D (2006) Future visions of technology-enhanced professional learning, Proceedings - Sixth International Conference on Advanced Learning Technologies, ICALT 2006 2006 pp. 542-543
The paper presents future visions of technology-enhanced professional learning as expressed in a panEuropean roadmapping activity. The paper introduces a new approach to developing a roadmap for technology-enhanced professional learning. Interesting findings from the first phase, which identified the future visions are presented. © 2006 IEEE.
Fryan LB, Stergioulas L (2011) Critical success factors for the adoption of eLearning in the kingdom of Saudi Arabia educational institutions, Proceedings of the European Conference on Games-based Learning 1 pp. 63-72
In recent years, Electronic Learning (eLearning) has gained interest and has been widely adopted and acknowledged; it is integrated in many institutions' educational systems. Owing to the major transformation of traditional educational system in the Kingdom of Saudi Arabia (KSA), most of higher educational institutions are currently switching to eLearning system and the rest are expected to switch in the near future. Nowadays there is a universal need to investigate such Critical Success Factors (CSFs) that have significant impact on the adoption of eLearning. The aim of this paper is to identify and prioritise, in order of their importance, the Critical Success Factors (CSFs) for the adoption of eLearning in educational institutions of the Kingdom of Saudi Arabia (KSA). Therefore, the chosen area of research for this paper holds importance in terms of considering the CSFs before and during the adoption of eLearning process especially at this time when KSA is ready to prepare for this educational reform. Although the significance of eLearning cannot be denied and its impact on the improvement of the traditional educational system is well-recognised, there are still gaps reported in the literature for the adoption of eLearning. In order to fully realise the potential of eLearning and understand the challenges in its adoption, it is imperative to identify the CSFs that affect the adoption of eLearning in KSA educational institutions. In order to do so, this paper identifies key success factors that affect the adoption of eLearning through extensive analyses of case studies and the existing literature. For the case study analysis, five KSA educational institutions are investigated through interviews and questionnaires; for the purpose of literature review, data is collected from different resources such as journals, books, conferences papers, newspaper articles, magazines, etc. The research gap is identified so as to highlight the importance of this research. Additionally, the features and benefits of eLearning are discussed and the CSFs for eLearning adoption are identified and presented in a table with respective categorisations. The interpretive, qualitative data analysis methods are used, and findings are presented in tables and figures. Findings show that of the total 52 CSFs identified, 25% were highlighted only through interviews and survey questionnaires and were not found in the existing literature.
Markazi SA, Stergioulas LK, Ramchurn A, Bunce D (2007) Latency corrected wavelet filtering of the P300 event-related potential in young and old adults, Proceedings of the 3rd International IEEE EMBS Conference on Neural Engineering pp. 582-586
The purpose of this study was to apply a nonlinear wavelet denoising Alter to the extraction of transient evoked related potentials (ERPs) from background EEG. The study introduces a new method for Altering the P300, an ERP component evoked by performing a given cognitive task, in this case, a two-choice reaction time task. The method employed latency correction of the ERPs in the time domain, followed by noise-masking in the wavelet domain. With this filtering method, the P300 component was accurately localized in both time and scale. Wilcoxon tests verified the statistical significance of P300 peak amplitude differences (p
Hu J, Wang Z, Gao H, Stergioulas LK (2012) Robust H ? sliding mode control for discrete time-delay systems with stochastic nonlinearities, Journal of the Franklin Institute 349 (4) pp. 1459-1479
This paper is concerned with the robust H? sliding mode control (SMC) problem for a general class of discrete time-delay uncertain systems with stochastic nonlinearities. The time-varying delay is unknown with given lower and upper bounds, and the stochastic nonlinearities are described by statistical means. The purpose of the problem addressed is to integrate the SMC method with the H? technique such that, for all admissible parameter uncertainty, unmatched stochastic nonlinearities, time-varying delay and unmatched external disturbance, the closed-loop system is asymptotically mean-square stable while achieving a prescribed disturbance attenuation level. Sufficient conditions are presented to ensure the desired performance of the system dynamics in the specified sliding surface by solving a semi-definite programming problem. Moreover, a discrete-time SMC law is synthesized to ensure the reaching condition. A simulation example is given to illustrate the validity of the proposed SMC scheme. © 2011 The Franklin Institute. Published by Elsevier Ltd. All rights reserved.
Kuljis J, Paul RJ, Stergioulas LK (2007) Can health care benefit from modeling and simulation methods in the same way as business and manufacturing has?, Proceedings - Winter Simulation Conference pp. 1449-1453
It has been increasingly recognized that the application of simulation methods can be instrumental in addressing the multi-faceted challenges health care is facing at present and more importantly in the future. But the application of these methods seems not to be as widespread as in other sectors, where such methods when used as part of their core operation, reap significant benefits. This paper examines the potential use of modeling and simulation in health care, drawing the parallels and marking the mismatches from the business and manufacturing world. Methods from the latter sectors will be reviewed with the intention to assess their potential usefulness to healthcare. To focus this discussion, we propose and discuss seven axes of differentiation: patient fear of death; medical practitioners (for example approach to healing, investigation by experimentation and finance); healthcare support staff; health care managers; political influence and control; 'society's view'; and utopia.
Nunome H, Lake M, Georgakis A, Stergioulas LK (2006) Impact phase kinematics of instep kicking in soccer, Journal of Sports Sciences 24 (1) pp. 11-22
The purpose of this study was to capture the lower limb kinematics before during and after ball impact of soccer kicking by examining the influence of both sampling rate and smoothing procedures. Nine male soccer players performed maximal instep kicks and the three-dimensional leg movements were captured at 1000 Hz. Angular and linear velocities and accelerations were determined using four different processing approaches: processed using a modified version of a time-frequency filtering algorithm (WGN), smoothed by a second-order low-pass Butterworth filter at 200 Hz cut-off (BWF), re-sampled at 250 Hz without smoothing (RSR) and re-sampled at 250 Hz but filtered by the same Butterworth filter at 10 Hz cut-off (RSF). The WGN approach appeared to establish representative kinematics, whereas the other procedures failed to remove noisy oscillation from the baseline of signal (BWF), lost the peaks of rapid changes (RSR) or produced totally distorted movement patterns (RSF). The results indicate that the procedures used by some previous studies may have been insufficient to adequately capture the lower limb motion near ball impact. We propose a new time-frequency filtering technique as a better way to smooth data whose frequency content varies dramatically. © 2006 Taylor & Francis.
Naseer A, Stergioulas LK (2010) Web-services-based resource discovery model and service deployment on healthgrids, IEEE Transactions on Information Technology in Biomedicine 14 (3) pp. 838-845
HealthGrids represent the next generation of advanced healthcare IT and hold the promise to untangle complex healthcare-data problems by integrating health information systems and healthcare entities. Healthcare could benefit from a new delivery approach using HealthGrids to better meet the biomedical and health-related needs. Specialized services are needed to provide unified discovery of and ubiquitous access to available HealthGrid resources. The different types of services available on HealthGrids are classified into two levels, the operational-level services and the management-level services. This paper takes a fresh approach to address the problems of resource discovery in HealthGrids based on Web services (WS) and WS technologies and proposes a WS-based resource discovery model. © 2006 IEEE.
Ezz I, Loureiro-Koechlin C, Stergioulas L (2012) An investigation of the use of simulation tools in management education, Proceedings - Winter Simulation Conference
This paper investigates the use of simulation tools for business education, including Management School education and managerial training. The paper provides an overview of the need for non-traditional tools for learning, and the importance of simulation in learning. A particular focus is placed on the need for openness of these tools, aiming to promote their use and re-use. These needs were confirmed by the results of a brief study on simulation tools. An example of open simulation content provision is given by the OpenScout portal, which provides access to open educational resources in the area of management education and training. OpenScout offers a collection of resources from multiple sources located in different European countries. Initial experience from this initiative of collecting open simulation content demonstrated the limited availability of such type of resources. © 2012 IEEE.
Kamtsiou V, Koskinen T, Naeve A, Pappa D, Stergioulas L (2006) A glimpse at the future of technology enhanced-professional learning: Trends, scenarios and visions, CEUR Workshop Proceedings 213 pp. 39-52
The paper presents future visions of technology enhanced professional learning as expressed in a pan-European roadmapping activity. A new approach is introduced and employed to develop a roadmap for technology enhanced professional learning. Interesting findings from the first phase, which identified the future visions are presented and their analysis using conceptual mapping is proposed.
Qazi S, Georgakis A, Stergioulas LK, Shikh-Bahaei M (2007) Interference suppression in the Wigner distribution using fractional fourier transformation and signal synthesis, IEEE Transactions on Signal Processing 55 (6 II) pp. 3150-3154
A novel method for the suppression of cross terms in the time-frequency domain is introduced. First, interference is identified using a fractional Fourier transform-based technique. Then, auto-terms are detected, synthesized, and subtracted from the original signal. The process is repeated until all signal components are extracted. Finally, the Wigner distributions of pure auto-terms are superimposed to yield a high readability representation. © 2007 IEEE.
Pappa D, Telonis P, Stergioulas LK (2006) Management of medicines information for patient safety, Journal of Telemedicine and Telecare 12 (SUPPL. 1)
Ensuring patient safety in the management of medicines requires the efficient collection, administration, analysis and distribution of huge amounts of data from different sources. This requires the development of generic methods and tools for tasks such as: (1) data mining and semantics-based inference; (2) integration of heterogeneous scientific information databases relating to drugs and diseases; (3) terminology and coding issues; (4) adverse drug events and signal detection; and (5) networking and security. Collaborative research and development will be required to develop coordinated health care information services. Easy access to high-quality information will provide better health care and increased cost efficiency.
Jahangirian M, Taylor SJE, Eatock J, Stergioulas LK, Taylor PM (2014) Causal study of low stakeholder engagement in healthcare simulation projects, Journal of the Operational Research Society
Serif T, Ghinea G, Stergioulas L, Chen SY, Tiropanis T, Tsekeridou S (2009) Satellite-based delivery of educational content to geographically isolated communities: A service based approach, Personal and Ubiquitous Computing 13 (3) pp. 229-241
Enabling learning for members of geographically isolated communities presents benefits in terms of promoting regional development and cost savings for governments and companies. However, notwithstanding recent advances in e-Learning, from both technological and pedagogical perspectives, there are very few, if any, recognised methodologies for user-led design of satellite-based e-learning infrastructures. In this paper, we present a methodology for designing a satellite and wireless based network infrastructure and learning services to support distance learning for such isolated communities. This methodology entails (a) the involvement of community members in the development of targeted learning services from an early stage, and (b) a service-oriented approach to learning solution deployment. Results show, that, while the technological premises of distance learning can be accommodated by hybrid satellite/wireless infrastructures, this has to be complemented with (a) high-quality audio-visual educational material, and (b) the opportunity for community members to interact with other community members either as groups (common-room oriented scenarios) or individuals (home-based scenarios), thus providing an impetus for learner engagement in both formal and informal activities. © pringer-Verlag London Limited 2007.
Mohammad Y, Stergioulas L (2011) The NPfiT strategy for information security of care record service, Proceedings of the European, Mediterranean and Middle Eastern Conference on Information Systems - Informing Responsible Management: Sustainability in Emerging Economies, EMCIS 2011 pp. 237-251
The National Programme for IT in England doesn't have a one-document strategy for its information security of the Care Records Service, which is the national EHR system. This paper provides a comprehensive understanding of the information security strategy of England's EHR system by presenting its different information security issues such as consent mechanisms, access control, sharing level, and related legal and regulations documents.
Yusof MM, Papazafeiropoulou A, Paul RJ, Stergioulas LK (2008) Investigating evaluation frameworks for health information systems, International Journal of Medical Informatics 77 (6) pp. 377-385
Background and purpose: Evaluation of health information systems (HIS) enables the assessment of the extent to which HIS are fulfilling their objectives in supporting the services of healthcare delivery. This paper presents an overview of evaluation in health informatics and information systems. Methods: Literature review on discourses, dimensions and methods of HIS and IS evaluation. A critical appraisal of selected HIS and IS evaluation frameworks is undertaken in order to identify HIS evaluation dimensions and measures. The frameworks are compared based on their inclusion of human, organizational and technological factors. Results: We found that an increasing number of evaluation studies deal with two distinct trends of HIS: one considers human and organizational issues and the other is concerned with the employment of a subjectivist approach. Our review indicates that current evaluation methods complement each other in that they evaluate different aspects of HIS and they can be improved upon. Conclusions: Evaluation is complex; it is easy to measure many things but not necessarily the right ones. Nevertheless, it is possible to consider, a HIS evaluation framework with more comprehensive and specific measures that would incorporate technological, human and organizational issues to facilitate HIS evaluation. © 2007 Elsevier Ireland Ltd. All rights reserved.
Boultadakis GE, Kalognomos GK, Karakasiliotis AV, Frangos PV, Stergioulas LK (2009) A comparative study of bilinear time-frequency transforms of isar signals for air target imaging, Elektronika ir Elektrotechnika (4) pp. 87-92
In this paper a comparative study of bilinear time-frequency (TF) transforms for Inverse Synthetic Aperture Radar (ISAR) imaging is presented. Following a concise presentation of the ISAR imaging method used in this work, as well as of the theory of the bilinear TF transforms involved in our numerical simulations, extended numerical results are presented for a reference simulated radar target and for various noise conditions. The constructed ISAR images are presented and analyzed quantitatively using an entropy cost function criterion, while corresponding run-time considerations have also been taken into account. As a result, it appears that the Smoothed Pseudo Wigner-Ville (SPWV) distribution provides us with images of superior quality. Furthermore, the analysis of the results demonstrates the usefulness of bilinear TF methods in ISAR imaging and showcases the relative performance advantages and disadvantages of the various distributions. Ill. 7, bibl. 22 (in English; summaries in English, Russian and Lithuanian).
Jahangirian M, Eldabi T, Naseer A, Stergioulas LK, Young T (2010) Simulation in manufacturing and business: A review, European Journal of Operational Research 203 (1) pp. 1-13
This paper reports the results of a review of simulation applications published within peer-reviewed literature between 1997 and 2006 to provide an up-to-date picture of the role of simulation techniques within manufacturing and business. The review is characterised by three factors: wide coverage, broad scope of the simulation techniques, and a focus on real-world applications. A structured methodology was followed to narrow down the search from around 20,000 papers to 281. Results include interesting trends and patterns. For instance, although discrete event simulation is the most popular technique, it has lower stakeholder engagement than other techniques, such as system dynamics or gaming. This is highly correlated with modelling lead time and purpose. Considering application areas, modelling is mostly used in scheduling. Finally, this review shows an increasing interest in hybrid modelling as an approach to cope with complex enterprise-wide systems. © 2009 Elsevier B.V. All rights reserved.
Yusof MM, Stergioulas L, Zugic J (2007) Health information systems adoption: findings from a systematic review., Stud Health Technol Inform 129 (Pt 1) pp. 262-266
Earlier evaluation studies on Health Information Systems (HIS) adoption have highlighted a large number of adoption problems that were attributed to the lack of fit between technology, human and organisation factors. Lessons can be learned from these evaluation studies by identifying the most important factors of HIS adoption. In order to study the adoption issue, a qualitative systematic review has been performed using a recently introduced framework, known as HOT-fit (Human, Organisation and Technology fit). The paper identifies and highlights the following critical adoption factors: technology (ease of use, system usefulness, system flexibility, time efficiency, information accessibility and relevancy); human (user training, user perception, user roles, user skills, clarity of system purpose, user involvement); organisation (leadership and support, clinical process, user involvement, internal communication, inter organisational system, as well as the fit between them. The findings can be used to guide future system development and inform relevant decision making.
Hu J, Wang Z, Gao H, Stergioulas LK (2012) Robust sliding mode control for discrete stochastic systems with mixed time delays, randomly occurring uncertainties, and randomly occurring nonlinearities, IEEE Transactions on Industrial Electronics 59 (7) pp. 3008-3015
This paper investigates the robust sliding mode control (SMC) problem for a class of uncertain nonlinear stochastic systems with mixed time delays. Both the sectorlike nonlinearities and the norm-bounded uncertainties enter into the system in random ways, and such randomly occurring uncertainties and randomly occurring nonlinearities obey certain mutually uncorrelated Bernoulli distributed white noise sequences. The mixed time delays consist of both the discrete and the distributed delays. The time-varying delays are allowed in state. By employing the idea of delay fractioning and constructing a new Lyapunov-Krasovskii functional, sufficient conditions are established to ensure the stability of the system dynamics in the specified sliding surface by solving a certain semidefinite programming problem. A full-state feedback SMC law is designed to guarantee the reaching condition. A simulation example is given to demonstrate the effectiveness of the proposed SMC scheme. © 2012 IEEE.
Hu J, Wang Z, Gao H, Stergioulas LK (2012) Probability-guaranteed H? finite-horizon filtering for a class of nonlinear time-varying systems with sensor saturations, Systems and Control Letters 61 (4) pp. 477-484
In this paper, the probability-guaranteed H? finite-horizon filtering problem is investigated for a class of nonlinear time-varying systems with uncertain parameters and sensor saturations. The system matrices are functions of mutually independent stochastic variables that obey uniform distributions over known finite ranges. Attention is focused on the construction of a time-varying filter such that the prescribed H? performance requirement can be guaranteed with probability constraint. By using the difference linear matrix inequalities (DLMIs) approach, sufficient conditions are established to guarantee the desired performance of the designed finite-horizon filter. The time-varying filter gains can be obtained in terms of the feasible solutions of a set of DLMIs that can be recursively solved by using the semi-definite programming method. A computational algorithm is specifically developed for the addressed probability-guaranteed H? finite-horizon filtering problem. Finally, a simulation example is given to illustrate the effectiveness of the proposed filtering scheme. © 2012 Elsevier B.V. All rights reserved.
Zou L, Wang Z, Stergioulas LK (2014) State estimation for a class of complex networks with event-triggered transmission scheme, ICAC 2014 - Proceedings of the 20th International Conference on Automation and Computing: Future Automation, Computing and Manufacturing pp. 289-294
© 2014 Chinese Automation and Computing Society in the UK-CACS.In this paper, the state estimation problem is investigated for a class of complex networks with the event-triggered transmission scheme. Different from the periodically triggered communication, the measurement from the sensors is transmitted to the estimator only when the so-called "event-triggered condition" is satisfied in the event-triggered transmission scheme, thereby reducing the unnecessary network traffic between the sensors and the estimator. Attention is focused on the analysis and design of the estimator subject to the predetermined event-triggered transmission scheme such that the estimation error is bounded in mean square. Sufficient conditions are obtained for the existence of admissible estimators. The desired estimator gain matrices is derived via solving a convex problem based on Lyapunov theory combined with the stochastic analysis approach. A numerical example is given to illustrate the effectiveness of the results.
Mohammad Y, Stergioulas L (2010) Building an information security strategy for EHR: Guidelines for assessing the current situation, 2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10 pp. 3919-3922
This paper is looking at electronic health record (EHR) systems and their information security strategy. It focuses on the first step of building an information security strategy which is analysing the current situation of an EHR system. This research is based on different research methods applied to different EHR systems. In this paper we define eight elements that can be used as guidelines for how best to assess the current situation of any EHR system. © 2010 IEEE.
Stergioulas LK, Loureiro-Koechlin C (2011) Exploring metadata standards for competence descriptions in the business & management domain, Proceedings of the European, Mediterranean and Middle Eastern Conference on Information Systems - Informing Responsible Management: Sustainability in Emerging Economies, EMCIS 2011 pp. 727-733
This paper explores the development and use of competency metadata standards. As there has recently been a surge of a number of standards to address the challenge of representing competencies and there is a rising need to develop a common methodology, as well as methods and tools for developing, reusing, adapting, integrating such standards, this research is now becoming important and timely. We explore this within the context of the OpenScout project, which is building a federation of repositories with content in the areas of business and management. Thus this study is limited to metadata standards for competencies in the business and management fields, but it is aimed that the lessons from this domain can transfer to other fields and will inform the wider debate on the development and use of such standards. The paper revisits a set of standards for competence descriptions and provides recommendations as to which standard would suit better the nature of the repository, the requirements of stakeholders, and the Open Content resources. In particular, the paper proposes an adaptation and extension of the IEEE-RCD model, employing an application profiling approach, and taking into account the granularity of the European Qualifications Framework and the requirements of Open Content resources.
Naseer A, Stergioulas LK (2006) Discovering HealthGrid services, Proceedings - 2006 IEEE International Conference on Services Computing, SCC 2006 pp. 301-306
HealthGrids represent the next generation of advanced healthcare IT and hold the promise to resolve complex healthcare problems by integrating health information systems and healthcare entities. Healthcare could benefit from a new delivery approach using HealthGrids to better meet the bio-medical and health-related needs. Specialized services are needed to provide unified discovery of and ubiquitous access to available HealthGrid resources. This paper identifies different types of services available on HealthGrids and classifies them into two-levels, the Operational Level and the Management Level. © 2006 IEEE.
Markazi SA, Qazi S, Stergioulas LS, Ramchurn A, Bunce D (2006) Wavelet filtering of the P300 component in event-related potentials, Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings pp. 1719-1722
This paper presents an application of wavelet filtering to single-trial P300 component analysis. The objective of this study is to introduce a new method for analyzing the P300 component, when performing a given cognitive task, in this case, a two-choice reaction time task. The discrete wavelet transform with Daubechies wavelet is employed to detect the presence of P300 in individual trials. Wavelet filtering is applied to remove noise and unwanted frequency components from discrete wavelet transform (DWT) coefficients based on prior knowledge of event-related potentials (ERPs). The filtering mask is computed from the grand-average of wavelet coefficients over all participants. With this filtering, the P300 component is accurately localized in both time and scale. The findings suggest the procedure to have considerable potential for the analysis of time-series data in the behavioral neurosciences. © 2006 IEEE.
Abbasi M, Stergioulas LK, El-Haddadeh R, Kretschmer M, Pitsilis V, Tsiolis I, Zagkos D, Hatziefremidis A (2008) Interoperability and testing in broadband satellite networks, 10th International Workshop on Signal Processing for Space Communications, SPSC 2008
By combining satellite and terrestrial (wireless) technologies, full coverage and high capacity can be achieved for true broadband services. The interoperability of such diverse networks imposes a number of challenges regarding service provision and management. The end-to-end quality of service (QoS) management implies that features such as service scalability between different networks have to be available. On the other hand, wireless QoS capabilities provide a promising diversity for a wide range of seamless applications. However, differences in QoS properties between both the wired and the wireless applications have a considerable effect on the quality level as well as platform and application dimensions of network interoperability. This paper examines the so-called interoperability requirements in integrated uses of satellite communication technology together with terrestrial (wireless) network technology for seamless delivery of broadband services (using ISABEL and CLIX e-learning applications) in rural and remote areas. This is demonstrated with an example of two educational, real-time and recorded, eLearning services. ©2008 IEEE.
Ghinea G, Stergioulas L, Chen S, Tiropanis T, Tsekeridou S (2009) Special issue on "Ubiquitous e-learning solutions over heterogeneous networks", Personal and Ubiquitous Computing 13 (3) pp. 179-180
Abd-Elaziz A, Ezz I, Papazafeiropoulou A, Paul R, Stergioulas L (2011) Investigating the critical success factors and infrastructure of knowledge management for open innovation adoption: The case of GlaxoSmithKline (GSK) in Egypt, Proceedings of the Annual Hawaii International Conference on System Sciences pp. 4022-4031
During the past few years organizations are moving towards the adoption of open innovation models to make use both internal and external knowledge. Recent efforts concerning open innovation involve building portfolio of relationships and networks that provide access to technology, information and knowledge. For successful open innovation implementation knowledge management (KM) strategies adopting its frameworks are important. This study investigates the critical success factors for the underlying KM frameworks in developing countries. The case of GlaxoSmithKline (GSK) has been investigated as one of the few examples of KM initiatives in Egypt. A comparison of GSK's critical success factors of its KM framework between the cases of its headquarters and its Egyptian branch, resulted in identifying a set of factors that have been customized for GSK Egypt specifically. We further argue that these newly identified, additional factors, could serve as lessons learnt for others. © 2012 IEEE.
Yusof MM, Kuljis J, Papazafeiropoulou A, Stergioulas LK (2008) An evaluation framework for Health Information Systems: human, organization and technology-fit factors (HOT-fit), International Journal of Medical Informatics 77 (6) pp. 386-398
Background and purpose: The realization of Health Information Systems (HIS) requires rigorous evaluation that addresses technology, human and organization issues. Our review indicates that current evaluation methods evaluate different aspects of HIS and they can be improved upon. A new evaluation framework, human, organization and technology-fit (HOT-fit) was developed after having conducted a critical appraisal of the findings of existing HIS evaluation studies. HOT-fit builds on previous models of IS evaluation-in particular, the IS Success Model and the IT-Organization Fit Model. This paper introduces the new framework for HIS evaluation that incorporates comprehensive dimensions and measures of HIS and provides a technological, human and organizational fit. Methods: Literature review on HIS and IS evaluation studies and pilot testing of developed framework. The framework was used to evaluate a Fundus Imaging System (FIS) of a primary care organization in the UK. The case study was conducted through observation, interview and document analysis. Results: The main findings show that having the right user attitude and skills base together with good leadership, IT-friendly environment and good communication can have positive influence on the system adoption. Conclusions: Comprehensive, specific evaluation factors, dimensions and measures in the new framework (HOT-fit) are applicable in HIS evaluation. The use of such a framework is argued to be useful not only for comprehensive evaluation of the particular FIS system under investigation, but potentially also for any Health Information System in general. © 2007 Elsevier Ireland Ltd. All rights reserved.
Serif T, Stergioulas L, Ghinea G, Moatsos M, Makropoulos C, Tsekeridou S, Tiropanis T (2006) Satellite-enabled interactive educations scenarios and systems architectures, Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) 4227 LNCS pp. 411-423
There are specific sectors of the economy that can benefit from satellite-based tele-education. Areas, such as maritime and agriculture, share common needs for both broadband connectivity at remote geographical areas that cannot otherwise be covered, and for innovative content for tele-education purposes. Furthermore, each area has special requirements with regard to the type of content to be delivered. In this paper we propose a set of architectural designs and case scenarios that will realise such interactive end-to-end education systems based on satellite communications. Services requirements in this setting are also identified and discussed. © Springer-Verlag Berlin Heidelberg 2006.
Thayaparan T, Frangos P, Stankovic L, Stergioulas L, Lazarov AD (2008) Editorial: Signal processing techniques for ISAR and feature extraction, IET Signal Processing 2 (3) pp. 189-191
Yusof MM, Stergioulas L, Zugic J (2007) Health information systems adoption: findings from a systematic review., Medinfo. MEDINFO 12 (Pt 1) pp. 262-266
Earlier evaluation studies on Health Information Systems (HIS) adoption have highlighted a large number of adoption problems that were attributed to the lack of fit between technology, human and organisation factors. Lessons can be learned from these evaluation studies by identifying the most important factors of HIS adoption. In order to study the adoption issue, a qualitative systematic review has been performed using a recently introduced framework, known as HOT-fit (Human, Organisation and Technology fit). The paper identifies and highlights the following critical adoption factors: technology (ease of use, system usefulness, system flexibility, time efficiency, information accessibility and relevancy); human (user training, user perception, user roles, user skills, clarity of system purpose, user involvement); organisation (leadership and support, clinical process, user involvement, internal communication, inter organisational system, as well as the fit between them. The findings can be used to guide future system development and inform relevant decision making.
Naseer A, Eldabi T, Jahangirian M, Stergioulas L (2008) Potential applications of simulation modelling techniques in healthcare: Lessons learned from aerospace & military, Proceedings of the European and Mediterranean Conference on Information Systems, EMCIS 2008
The Aerospace and Military areas are to do with complex missions and situations. Modelling and Simulation (M&S) has been applied in many areas of defence ranging from space sciences, satellite engineering to multi-warfare (air warfare, undersea warfare), air & missile defence, acquisition, tactical military trainings & exercises, national security analysis and strategic decision making & planning, etc. The application of simulation modelling techniques in healthcare would improve the provision of healthcare services; however, their application has been much relatively feeble in the healthcare sector as compared to the defence sector. This paper presents results from a systematic literature survey on applications of modelling simulation techniques in the Aerospace & Military. The knowledge gained or lessons learned from the survey were finally used to analyze the potential applications of the simulation modelling techniques to the healthcare sector. Results show that in the defence sector, Distributed Simulation has now become a widely adopted technique. However, System Dynamics (SD) and Discrete Event Simulation (DSE) have also gained relative attention. From this survey it becomes clear that various simulation modelling techniques are useful for specific purposes and have potential applications in the healthcare sector.
Pappa DD, Stergioulas LK, Telonis P (2009) The role of knowledge management in the pharmaceutical enterprise, International Journal of Technology Management 47 (1-3) pp. 127-144
In the knowledge intensive pharmaceutical sector, novelty and value are essential for corporate success. This paper discusses the requirements for, and the role of, effective Knowledge Management, as a means for business optimisation and improvement in terms of performance and competitiveness. The various types of knowledge resources are identified and major issues for both explicit/informational and tacit/behavioural assets are discussed. It is argued that the key challenges for the future are underpinned by the rapidly increasing need for more effective communication, either between systems or between people. Intelligent information processing and improved knowledge transfer and sharing are called for. Copyright © 2009 Inderscience Enterprises Ltd.
Naseer A, Stergioulas LK (2009) HealthGrids in health informatics: A taxonomy, pp. 124-143
Healthcare is a vast domain encapsulating not only multiple sub-domains or sub-sectors but also many diverse operations and logistics within each sub-sector. This diversity needs to be handled in a systematic and well-characterized manner in order to maintain consistency of various healthcare tasks. Integration of health information systems within each healthcare sub-sectors is crucial for ubiquitous access and sharing of information. The emerging technology of HealthGrids holds the promise to successfully integrate health information systems and various healthcare entities onto a common, globally shared and easily accessible platform. Many different types of HealthGrids exist but there lacks a taxonomy to classify them into a hierarchical order. This chapter presents a well-characterized taxonomy of different types of HealthGrid and classifies them into four major types, namely BioGrid, MediGrid, PharmaGrid and CareGrid. Each of these HealthGrids possesses dedicated features and functionalities. The proposed taxonomy serves to better understand the realtionship among various HealthGrid types and would lay a basis for future research. © 2010, IGI Global.
Yusof MM, Paul RJ, Stergioulas LK (2006) Towards a framework for health information systems, Proceedings of the Annual Hawaii International Conference on System Sciences 5
The evaluation of Health Information Systems (HIS) is crucial to ensure their effective implementation and positive impact on healthcare delivery. A review of HIS evaluation studies was carried out which indicated that the improvement of current methods is required. In order to satisfy this requirement, a new framework is introduced for the evaluation of Information Systems (IS) in healthcare settings. The proposed HOT-fit framework (Human, Organization and Technology-fit) was developed after having critically appraised the existing findings of HIS evaluation studies. It also builds on previous models of IS evaluation, in particular, the IS Success Model and the IT-Organization Fit Model. HOT-fit incorporates the concept of fit between technology, human and organization. The paper outlined the proposed methodology of a Fundus Imaging Systems in a primary care in the UK. The framework can be potentially used as a tool to conduct better and comprehensive HIS evaluation. © 2006 IEEE.
Hu J, Wang Z, Niu Y, Stergioulas LK (2012) H ? sliding mode observer design for a class of nonlinear discrete time-delay systems: A delay-fractioning approach, International Journal of Robust and Nonlinear Control 22 (16) pp. 1806-1826
In this paper, the H ? sliding mode observer (SMO) design problem is investigated for a class of nonlinear discrete time-delay systems. The nonlinear descriptions quantify the maximum possible derivations from a linear model, and the system states are allowed to be immeasurable. Attention is focused on the design of a discrete-time SMO such that the asymptotic stability as well as the H ? performance requirement of the error dynamics can be guaranteed in the presence of nonlinearities, time delay and external disturbances. Firstly, a discrete-time discontinuous switched term is proposed to make sure that the reaching condition holds. Then, by constructing a new Lyapunov-Krasovskii functional based on the idea of 'delay fractioning' and by introducing some appropriate free-weighting matrices, a sufficient condition is established to guarantee the desired performance of the error dynamics in the specified sliding mode surface by solving a minimization problem. Finally, an illustrative example is given to show the effectiveness of the designed SMO design scheme. Copyright © 2011 John Wiley & Sons, Ltd. Copyright © 2011 John Wiley & Sons, Ltd.
Fakhimi M, Anagnostou A, Stergioulas L, Taylor SJE (2014) A hybrid agent-based and Discrete Event Simulation approach for sustainable strategic planning and simulation analytics, Proceedings - Winter Simulation Conference 2015-January pp. 1573-1584
© 2014 IEEE.Modern healthcare reforms are required to be financially, environmentally and socially sustainable in order to address the additional constraints of financial resources shrinkage, pressure to reduce the environmental impacts and demand for improving the quality of healthcare services. Decision makers face the challenge of balancing all three aspects when planning. However, implementing such an approach, particularly in healthcare, is not a trivial task. Modeling & simulation is a valuable tool for studying complex systems. This paper investigates the application of a hybrid approach that combines Agent-based Modeling & Simulation (ABMS) and Discrete-Event Simulation (DES) for analyzing sustainable planning strategies for Emergency Medical Services. The paper presents a case study that shows how combined ABMS and DES models can support strategic planning and simulation analytics, respectively. The generated data from the ABMS is fed to the DES model in order to analyze the different strategies and the preliminary results are promising.
Markazi SA, Qazi S, Stergioulas LS, Ramchurn A, Bunce D (2006) Wavelet filtering of the P300 component in event-related potentials., Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference pp. 1719-1722
This paper presents an application of wavelet filtering to single-trial P300 component analysis. The objective of this study is to introduce a new method for analyzing the P300 component, when performing a given cognitive task, in this case, a two-choice reaction time task. The discrete wavelet transform with Daubechies wavelet is employed to detect the presence of P300 in individual trials. Wavelet filtering is applied to remove noise and unwanted frequency components from discrete wavelet transform (DWT) coefficients based on prior knowledge of event-related potentials (ERPs). The filtering mask is computed from the grand-average of wavelet coefficients over all participants. With this filtering, the P300 component is accurately localized in both time and scale. The findings suggest the procedure to have considerable potential for the analysis of time-series data in the behavioral neurosciences.
Abbasi M, Stergioulas LK, Kretschmer M, Pitsilis V, Khalid Z, Khan N (2008) Heterogeneous satellite-terrestrial technologies: Quality of service and availability testing, Proceedings - 4th IEEE International Conference on Emerging Technologies 2008, ICET 2008 pp. 138-145
Due to rapid and constant evolution of wireless communication technologies, standards, protocols, applications, and systems, it is hard to rely on personal experience to make their selection, design and deployment. Testing helps to determine actual performance and limitations of technologies. Testing is also important to avoid the financial and reputation losses of the company as well as to ensure uninterrupted flow of the information for essential services such as healthcare, airports, railways, and military services. Testing covers many aspects of a communications network, including interoperability, conformance, performance and availability. The end-to-end quality of service management implies that features such as service scalability between different networks have to be available. However, wireless QoS requirements are very diverse due to its seamless applications, and moreover, , differences in QoS properties between both wired and wireless applications have a considerable effect on the level of user service quality as well as platform and application dimensions of network interoperability. The aim of this paper is to establish the network performance and availability requirements for the integrated use of satellite communication technology together with terrestrial network technology in a particular, niche application area, namely the seamless delivery of educational services in rural and remote areas. The suggested testing programme aims to identify the performance and availability issues for the operation of heterogeneous satellite-terrestrial network technologies.
Jahangirian M, Naseer A, Stergioulas L, Young T, Eldabi T, Brailsford S, Patel B, Harper P (2012) Simulation in health-care: Lessons from other sectors, Operational Research 12 (1) pp. 45-55
This paper compares the results of broad-range literature reviews over the period 1997-2006 on the application of simulation in three sectors: commerce, defence, and health-care. The main purpose of these reviews is to see whether there are lessons to learn from the first two sectors to be applied in the health-care sector. Results of our reviews show that, simulation has been commonly used in the three sectors; however, there is clear evidence of lack of consistency in the level of implementation. More specifically, healthcare lags behind the other two sectors, particularly in terms of stakeholder engagement and, consequently, in terms of implementation of simulation outcomes. This paper provides key insights into some challenges in applying simulation methods in healthcare, whilst presenting an up-to-date "big picture" of simulation in three main sectors from an academic point of view. © 2010 Springer-Verlag.
Fryan LB, Stergioulas L (2013) An investigation into best practices for e-learning implementation in higher education, CEUR Workshop Proceedings 1093 pp. 20-29
e-Learning has become an inevitable part of the modern education system, which deserves attention and investigation. This research aims to build a framework for best practice-in-context in the use and implementation of elearning tools, technology and systems in higher education (HE). The main contribution of this research is to provide a comprehensive framework that will potentially lead to the successful implementations of e-learning in HE. This paper reports on the limitations of existing frameworks and provides an overview of the research.
Naseer A, Stergioulas LK, Hammoud S, Li M (2008) Grid-based semantic integration and dissemination of medical information, 3rd International Conference on Digital Information Management, ICDIM 2008 pp. 272-278
Healthcare data and medical information need to be seamlessly accessible and available at all times to the various healthcare stakeholders. Inability to share, integrate and access critical healthcare information is a challenge for the healthcare IT. Moreover, semantic interoperability of health-related heterogeneous data sources is a challenging issue and HealthGrids are expected to address this challenge in a systematic manner. This paper proposes a new architecture: ASIDS (Architecture for Semantic Integration of Data Sources), that could be a potential candidate for solving the challenge of semantic interoperability of geographically distributed heterogeneous data sources. ASIDS has three main components that are loosely coupled (through interfaces) in a distributed manner. This architecture sets the basis for future research in terms of implementing a HealthGrid application in real environments. ©2008 IEEE.
Stergioulas L, Abassi M, Xydopoulos G, Fakhimi M, Margineanu R, Rifon LA, Iglesias MJF (2014) Evaluating E-learning platforms for schools: Use and usability, user acceptance, and impact on learning, Proceedings - IEEE 14th International Conference on Advanced Learning Technologies, ICALT 2014 pp. 19-21
© 2014 IEEE.Usability is widely acknowledged in the ICT-related literature as one of the most important factors that can directly affect the overall acceptance and success of any ICT application, tool, software, and platform. Ensuring usability is one of the main challenges of e-learning system developers. This paper describes two case studies designed to (i) evaluate the usability and (ii) assess the impact on school learning of the newly designed ODS Portal. The paper presents the development of the testing/evaluation methodology, the evaluation exercise, and the analysis of the results from an extensive 'use and usability' evaluation of the Open Discovery Space educational online platform.
Jahangirian M, Eldabi T, Garg L, Jun GT, Naseer A, Patel B, Stergioulas L, Young T (2011) A rapid review method for extremely large corpora of literature: Applications to the domains of modelling, simulation, and management, International Journal of Information Management 31 (3) pp. 234-243
While literature reviews with a large-scale scope are nowadays becoming a staple element of modern research practice, there are many challenges in taking on such an endeavour, yet little evidence of previous studies addressing these challenges exists. This paper introduces a practical and efficient review framework for extremely large corpora of literature, refined by five parallel implementations within a multi-disciplinary project aiming to map out the research and practice landscape of modelling, simulation, and management methods, spanning a variety of sectors of application where such methods have made a significant impact. Centred on searching and screening techniques along with the use of some emerging IT-assisted analytic and visualisation tools, the proposed framework consists of four key methodological elements to deal with the scale of the reviews, namely: (a) an incremental and iterative review structure, (b) a 3-stage screening phase including filtering, sampling and sifting, (c) use of visualisation tools, and (d) reference chasing (both forward and backward). Five parallel implementations of systematically conducted literature search and screening yielded a total initial search result of 146 087 papers, ultimately narrowed down to a final set of 1383 papers which was manageable within the limited time and other constraints of this research work. © 2010 Elsevier Ltd. All rights reserved.
Fakhimi M, Stergioulas L, Mustafee N, Eldabi T (2013) A review of literature in modeling approaches for sustainable development, Proceedings of the 2013 Winter Simulation Conference - Simulation: Making Decisions in a Complex World, WSC 2013 pp. 282-290
Modeling & Simulation (M&S) studies have been widely used in industry to gain insights into existing or proposed systems of interest. The majority of these studies focus on productivity-related measures to evaluate system' performance. However, this predominant focus on productivity may need to change since sustainability has become an increasingly important consideration in managerial discourse on organizational development. In this paper, the authors review and argue for a hybrid/mixed method approach towards modeling for sustainability; they present a review of literature with the aim of providing a synthesized view of M&S approaches which have previously been used to model sustainability; this study also explores the specific characteristics of sustainability in order to investigate the challenges in developing models for sustainability and to analyze what seems to be a holy grail for modelers. © 2013 IEEE.
Hu J, Wang Z, Gao H, Stergioulas LK (2012) Extended Kalman filtering with stochastic nonlinearities and multiple missing measurements, Automatica 48 (9) pp. 2007-2015
In this paper, the extended Kalman filtering problem is investigated for a class of nonlinear systems with multiple missing measurements over a finite horizon. Both deterministic and stochastic nonlinearities are included in the system model, where the stochastic nonlinearities are described by statistical means that could reflect the multiplicative stochastic disturbances. The phenomenon of measurement missing occurs in a random way and the missing probability for each sensor is governed by an individual random variable satisfying a certain probability distribution over the interval [0,1]. Such a probability distribution is allowed to be any commonly used distribution over the interval [0,1] with known conditional probability. The aim of the addressed filtering problem is to design a filter such that, in the presence of both the stochastic nonlinearities and multiple missing measurements, there exists an upper bound for the filtering error covariance. Subsequently, such an upper bound is minimized by properly designing the filter gain at each sampling instant. It is shown that the desired filter can be obtained in terms of the solutions to two Riccati-like difference equations that are of a form suitable for recursive computation in online applications. An illustrative example is given to demonstrate the effectiveness of the proposed filter design scheme. © 2012 Elsevier Ltd. All rights reserved.
Stergioulas Lampros, Abbasi Munir, Vassilopoulou P (2017) Technology roadmap for the Creative Industries, Creative Industries Journal 10 (1) pp. 40-58 Intellect
This paper discusses the findings of research conducted between 2013 and 2016, which concerned the development of technology roadmaps for the Creative Industries. The roadmap presented in this paper was built based on input from communities of creative and Information and Communication Technologies (ICT) experts collected during the consultation and validation phases of the research. It provides a synthesis of challenges and recommendations from the five creative sectors examined by the project ? Architecture, Art, Design, Games, Media and e-Publishing ? and proposes research directions for the development of desired future technologies, by highlighting innovative future developments in the Creative Industries, while also assessing their technology maturity in the short, medium and longer terms. By rating the desired technologies as ?present? (1?2 years), ?possible? (2--5 years), or ?probable? (5?10 years or beyond), the roadmap gives orientation towards the development of new technologies and related business models and skills and provides guidance for informed policy-making. The paper thus aims at enabling stakeholders ? creators, professionals, SMEs, creative groups, creative communities, associations, organisations and institutions, as well as governments and policy makers ? to maximise their benefit and the societal value from the new emerging technology landscape in the Creative Industries.
Pharmacovigilance has attracted enormous attention over recent decades. At present, the increasing datafication combined with the growing knowledge elicitation capabilities of key technology innovations, present pharmacovigilance with enormous opportunities to improve its effectiveness and widen its scope. With change being a continuous process, for pharmacovigilance this represents an era of ?Digital Darwinism?, during which new directions are opening fast and new challenges emerge, as to how the sector adapts in order to draw benefit. Current efforts and initiatives, aimed at addressing existing barriers and at enhancing the practical applications of new science and technology, are fragmented and disjoint, and thus are not adequate to provide an effective response to challenges. This research proposes a new paradigm for collaborative, information-driven innovation in pharmacovigilance and develops a Reference Framework, in order to (a) deepen the collective understanding of how a principled, collaborative and balanced medicines safety data ecosystem can be organised, (b) guide stakeholders towards the optimisation of pharmacovigilance and (c) provide useful reference points for the ongoing research and development process in the field. The Knowledge Discovery Cube (KDC) Framework provides the means for continual analysis, and for managing technology adoption in an informed and intentional manner. A variety of sources informed the research work. The resulting deliberations draw on the findings and conclusions of scholarly research, guidelines, policy documents and reports, and other resources from within and outside the field of health and life sciences, as well as on relevant theories. The developed framework was operationalised and validated in the context of vaccine safety monitoring.